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Items: 44


Results from an American pilot survey among Scleroderma Clinical Trials Consortium members on capillaroscopy use and how to best implement nailfold capillaroscopy training.

Snow MH, Saketkoo LA, Frech TM, Stever JR, Lebedoff N, Herrick AL, Cutolo M, Smith V.

Clin Exp Rheumatol. 2019 Apr 5. [Epub ahead of print] No abstract available.


Presence of Antitopoisomerase I Antibody Alone May Not Be Sufficient for the Diagnosis of Systemic Sclerosis.

Tebo AE, Schmidt RL, Frech TM.

J Rheumatol. 2019 Apr;46(4):440-442. doi: 10.3899/jrheum.180503. Epub 2019 Mar 1. No abstract available.


Factors Influencing Raynaud Condition Score Diary Outcomes in Systemic Sclerosis.

Pauling JD, Reilly E, Smith T, Frech TM.

J Rheumatol. 2019 Mar 1. pii: jrheum.180818. doi: 10.3899/jrheum.180818. [Epub ahead of print]


Patient-reported outcome instruments for assessing Raynaud's phenomenon in systemic sclerosis: A SCTC Vascular Working Group Report.

Pauling JD, Frech TM, Hughes M, Gordon JK, Domsic RT, Anderson ME, Ingegnoli F, McHugh NJ, Johnson SR, Hudson M, Boin F, Ong VH, Matucci-Cerinic M, Altorok N, Scolnik M, Nikpour M, Shah A, Pope JE, Khanna D, Herrick AL.

J Scleroderma Relat Disord. 2018 Oct;3(3):249-252. doi: 10.1177/2397198318774307. Epub 2018 May 24.


Amniotic membrane dressings: an effective therapy for SSc-related wounds.

Frech TM, McNeill C, Lebiedz-Odrobina D, Lewis G.

Rheumatology (Oxford). 2019 Apr 1;58(4):734-736. doi: 10.1093/rheumatology/key410. No abstract available.


Implications of endothelial shear stress on systemic sclerosis vasculopathy and treatment.

Frech TM, Machin DR, Murtaugh MA, Stoddard GJ, Bloom SI, Phibbs JV, Donato AJ.

Clin Exp Rheumatol. 2018 Jul-Aug;36 Suppl 113(4):175-182. Epub 2018 Sep 20. Review.


Determinants of health-related quality of life in a multinational systemic sclerosis inception cohort.

Morrisroe K, Hudson M, Baron M, de Vries-Bouwstra J, Carreira PE, Wuttge DM, Wang M, Frech TM, Stevens W, Proudman SM, Nikpour M; International Systemic Sclerosis Inception Cohort (INSYNC) collaboration.

Clin Exp Rheumatol. 2018 Jul-Aug;36 Suppl 113(4):53-60. Epub 2018 Aug 31.


Evolving symptoms of Raynaud's phenomenon in systemic sclerosis are associated with physician and patient-reported assessments of disease severity.

Pauling JD, Reilly E, Smith T, Frech TM.

Arthritis Care Res (Hoboken). 2018 Aug 21. doi: 10.1002/acr.23729. [Epub ahead of print]


Attenuated nitric oxide bioavailability in systemic sclerosis: Evidence from the novel assessment of passive leg movement.

Clifton HL, Machin DR, Groot HJ, Frech TM, Donato AJ, Richardson RS, Wray DW.

Exp Physiol. 2018 Oct;103(10):1412-1424. doi: 10.1113/EP086991. Epub 2018 Aug 18.


Can Routine Use of Patient-Reported Outcomes Help Guide Systemic Sclerosis Chronic Disease Care?

Frech TM, Hess R, Biber J, Young J, Hardman A, Weeks H, Peterson KA, Scholand MB.

J Clin Rheumatol. 2018 Aug;24(5):272-274. doi: 10.1097/RHU.0000000000000715. No abstract available.


Multinational Qualitative Research Study Exploring the Patient Experience of Raynaud's Phenomenon in Systemic Sclerosis.

Pauling JD, Domsic RT, Saketkoo LA, Almeida C, Withey J, Jay H, Frech TM, Ingegnoli F, Dures E, Robson J, McHugh NJ, Herrick AL, Matucci-Cerinic M, Khanna D, Hewlett S.

Arthritis Care Res (Hoboken). 2018 Sep;70(9):1373-1384. doi: 10.1002/acr.23475. Epub 2018 Aug 16.


Implementation of an advance directive focus in a Chronic Multi-Organ Rare Disease Clinic.

Elorreaga N, Allred D, Ortiz G, McNeill C, Scholand MB, Frech TM.

Ann Palliat Med. 2017 Dec;6(Suppl 2):S206-S208. doi: 10.21037/apm.2017.08.06. Epub 2017 Aug 31.


Gastrointestinal and Hepatic Disease in Systemic Sclerosis.

Frech TM, Mar D.

Rheum Dis Clin North Am. 2018 Feb;44(1):15-28. doi: 10.1016/j.rdc.2017.09.002. Review.


Patient acceptable symptom state in scleroderma: results from the tocilizumab compared with placebo trial in active diffuse cutaneous systemic sclerosis.

Arnold MB, Khanna D, Denton CP, van Laar JM, Frech TM, Anderson ME, Baron M, Chung L, Fierlbeck G, Lakshminarayanan S, Allanore Y, Riemekasten G, Steen V, Müller-Ladner U, Spotswood H, Burke L, Siegel J, Jahreis A, Furst DE, Pope JE.

Rheumatology (Oxford). 2018 Jan 1;57(1):152-157. doi: 10.1093/rheumatology/kex396.


Safety and efficacy of subcutaneous tocilizumab in systemic sclerosis: results from the open-label period of a phase II randomised controlled trial (faSScinate).

Khanna D, Denton CP, Lin CJF, van Laar JM, Frech TM, Anderson ME, Baron M, Chung L, Fierlbeck G, Lakshminarayanan S, Allanore Y, Pope JE, Riemekasten G, Steen V, Müller-Ladner U, Spotswood H, Burke L, Siegel J, Jahreis A, Furst DE.

Ann Rheum Dis. 2018 Feb;77(2):212-220. doi: 10.1136/annrheumdis-2017-211682. Epub 2017 Oct 24.


Acute oral tetrahydrobiopterin administration ameliorates endothelial dysfunction in systemic sclerosis.

Machin DR, Clifton HL, Richardson RS, Wray DW, Donato AJ, Frech TM.

Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 106(4):167-172. Epub 2017 Sep 14.


Oesophageal disease in systemic sclerosis: does heritability play a role?

Frech TM, Fakoya L, Gawron AJ, Wong J, Scholand MB, Sawitzke A, Peterson K.

Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 106(4):86-88. Epub 2017 Oct 2.


Automated Measurement of Microvascular Function Reveals Dysfunction in Systemic Sclerosis: A Cross-sectional Study.

Machin DR, Gates PE, Vink H, Frech TM, Donato AJ.

J Rheumatol. 2017 Nov;44(11):1603-1611. doi: 10.3899/jrheum.170120. Epub 2017 Sep 15.


Patient participation in patient-reported outcome instrument development in systemic sclerosis.

Pauling JD, Frech TM, Domsic RT, Hudson M.

Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 106(4):184-192. Epub 2017 May 2. Review.


Chronic Multiorgan Rare Disease: The Role of the Nurse Practitioner as a Leader of the Healthcare Team.

Allred D, Frech TM, McComber C, Peterson K, Ortiz G, McNeill C, Broadbent L, Elorreaga N, Miller T, Scholand MB.

J Med Pract Manage. 2017 May-Jun;32(6):413-416.


Reliability and Validity of the Tender and Swollen Joint Counts and the Modified Rodnan Skin Score in Early Diffuse Cutaneous Systemic Sclerosis: Analysis from the Prospective Registry of Early Systemic Sclerosis Cohort.

Gordon JK, Girish G, Berrocal VJ, Zhang M, Hatzis C, Assassi S, Bernstein EJ, Domsic RT, Hant FN, Hinchcliff M, Schiopu E, Steen VD, Frech TM, Khanna D.

J Rheumatol. 2017 Jun;44(6):791-794. doi: 10.3899/jrheum.160654. Epub 2017 Mar 15.


Utility of B-type natriuretic peptides in the assessment of patients with systemic sclerosis-associated pulmonary hypertension in the PHAROS registry.

Chung L, Fairchild RM, Furst DE, Li S, Alkassab F, Bolster MB, Csuka ME, Derk CT, Domsic RT, Fischer A, Frech TM, Gomberg-Maitland M, Gordon JK, Hinchcliff M, Hsu V, Hummers LK, Khanna D, Medsger TAJ, Molitor JA, Preston IR, Schiopu E, Shapiro L, Hant F, Silver R, Simms R, Varga J, Steen VD, Zamanian RT.

Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 106(4):106-113. Epub 2016 Nov 10.


Exercise-induced brachial artery blood flow and vascular function is impaired in systemic sclerosis.

Machin DR, Clifton HL, Garten RS, Gifford JR, Richardson RS, Wray DW, Frech TM, Donato AJ.

Am J Physiol Heart Circ Physiol. 2016 Dec 1;311(6):H1375-H1381. doi: 10.1152/ajpheart.00547.2016. Epub 2016 Sep 30.


Understanding empirical therapeutics in systemic sclerosis gastrointestinal tract disease.

Frech TM.

Rheumatology (Oxford). 2017 Feb;56(2):176-177. doi: 10.1093/rheumatology/kew322. Epub 2016 Sep 27. No abstract available.


Orofacial manifestations of systemic sclerosis.

Veale BJ, Jablonski RY, Frech TM, Pauling JD.

Br Dent J. 2016 Sep 23;221(6):305-10. doi: 10.1038/sj.bdj.2016.678.


Safety and efficacy of subcutaneous tocilizumab in adults with systemic sclerosis (faSScinate): a phase 2, randomised, controlled trial.

Khanna D, Denton CP, Jahreis A, van Laar JM, Frech TM, Anderson ME, Baron M, Chung L, Fierlbeck G, Lakshminarayanan S, Allanore Y, Pope JE, Riemekasten G, Steen V, Müller-Ladner U, Lafyatis R, Stifano G, Spotswood H, Chen-Harris H, Dziadek S, Morimoto A, Sornasse T, Siegel J, Furst DE.

Lancet. 2016 Jun 25;387(10038):2630-2640. doi: 10.1016/S0140-6736(16)00232-4. Epub 2016 May 5. Erratum in: Lancet. 2018 Apr 7;391(10128):1356.


Eosinophilic Esophagitis in Two Patients with Systemic Sclerosis.

Frech TM, Boynton K, Downs-Kelly E, Jones B, Kriesel JD, Peterson K.

Case Rep Rheumatol. 2016;2016:6410421. doi: 10.1155/2016/6410421. Epub 2016 Jan 20.


Genetic susceptibility loci of idiopathic interstitial pneumonia do not represent risk for systemic sclerosis: a case control study in Caucasian patients.

Wu M, Assassi S, Salazar GA, Pedroza C, Gorlova OY, Chen WV, Charles J, Taing ML, Liao K, Wigley FM, Hummers LK, Shah AA, Hinchcliff M, Khanna D, Schiopu E, Phillips K, Furst DE, Steen V, Baron M, Hudson M, Zhou X, Pope J, Jones N, Docherty P, Khalidi NA, Robinson D, Simms RW, Silver RM, Frech TM, Fessler BJ, Fritzler MJ, Molitor JA, Segal BM, Movahedian M, Martín J, Varga J, Mayes MD.

Arthritis Res Ther. 2016 Jan 20;18:20. doi: 10.1186/s13075-016-0923-3.


Sublingual Abnormalities in Systemic Sclerosis.

Frech TM, Pauling JD, Murtaugh MA, Kendall K, Domsic RT.

J Clin Rheumatol. 2016 Jan;22(1):19-21. doi: 10.1097/RHU.0000000000000339.


Primary care assessment of capillaroscopy abnormalities in patients with Raynaud's phenomenon.

Overbury R, Murtaugh MA, Fischer A, Frech TM.

Clin Rheumatol. 2015 Dec;34(12):2135-40. doi: 10.1007/s10067-015-3062-3. Epub 2015 Sep 23.


Protective role of interleukin-6 in systemic sclerosis gastrointestinal tract involvement: case report and review of the literature.

Frech TM, Hudson M.

Clin Exp Rheumatol. 2015 Jul-Aug;33(4 Suppl 91):S179-81. Epub 2015 Sep 1. Review.


Cardiac metabolomics and autopsy in a patient with early diffuse systemic sclerosis presenting with dyspnea: a case report.

Frech TM, Revelo MP, Ryan JJ, Shah AA, Gordon J, Domsic R, Hant F, Assassi S, Shanmugam VK, Hinchcliff M, Steen V, Khanna D, Bernstein EJ, Cox J, Luem N, Drakos S.

J Med Case Rep. 2015 Jun 10;9:136. doi: 10.1186/s13256-015-0587-7.


Antinuclear antibody-negative systemic sclerosis.

Salazar GA, Assassi S, Wigley F, Hummers L, Varga J, Hinchcliff M, Khanna D, Schiopu E, Phillips K, Furst DE, Steen V, Baron M, Hudson M, Taillefer SS, Pope J, Jones N, Docherty P, Khalidi NA, Robinson D, Simms RW, Silver RM, Frech TM, Fessler BJ, Molitor JA, Fritzler MJ, Segal BM, Al-Kassab F, Perry M, Yang J, Zamanian S, Reveille JD, Arnett FC, Pedroza C, Mayes MD.

Semin Arthritis Rheum. 2015 Jun;44(6):680-6. doi: 10.1016/j.semarthrit.2014.11.006. Epub 2014 Nov 28.


Informatics can identify systemic sclerosis (SSc) patients at risk for scleroderma renal crisis.

Redd D, Frech TM, Murtaugh MA, Rhiannon J, Zeng QT.

Comput Biol Med. 2014 Oct;53:203-5. doi: 10.1016/j.compbiomed.2014.07.022. Epub 2014 Aug 7.


Parental influence on systemic sclerosis.

Frech TM, Pimentel R, Mineau G, Sawitzke A, Penmetsa G, Wong J.

Arthritis Care Res (Hoboken). 2015 Feb;67(2):310-2.


Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis.

Mayes MD, Bossini-Castillo L, Gorlova O, Martin JE, Zhou X, Chen WV, Assassi S, Ying J, Tan FK, Arnett FC, Reveille JD, Guerra S, Teruel M, Carmona FD, Gregersen PK, Lee AT, López-Isac E, Ochoa E, Carreira P, Simeón CP, Castellví I, González-Gay MÁ; Spanish Scleroderma Group, Zhernakova A, Padyukov L, Alarcón-Riquelme M, Wijmenga C, Brown M, Beretta L, Riemekasten G, Witte T, Hunzelmann N, Kreuter A, Distler JH, Voskuyl AE, Schuerwegh AJ, Hesselstrand R, Nordin A, Airó P, Lunardi C, Shiels P, van Laar JM, Herrick A, Worthington J, Denton C, Wigley FM, Hummers LK, Varga J, Hinchcliff ME, Baron M, Hudson M, Pope JE, Furst DE, Khanna D, Phillips K, Schiopu E, Segal BM, Molitor JA, Silver RM, Steen VD, Simms RW, Lafyatis RA, Fessler BJ, Frech TM, Alkassab F, Docherty P, Kaminska E, Khalidi N, Jones HN, Markland J, Robinson D, Broen J, Radstake TR, Fonseca C, Koeleman BP, Martin J.

Am J Hum Genet. 2014 Jan 2;94(1):47-61. doi: 10.1016/j.ajhg.2013.12.002.


Treatment of early diffuse systemic sclerosis skin disease.

Frech TM, Shanmugam VK, Shah AA, Assassi S, Gordon JK, Hant FN, Hinchcliff ME, Steen V, Khanna D, Kayser C, Domsic RT.

Clin Exp Rheumatol. 2013 Mar-Apr;31(2 Suppl 76):166-71. Epub 2013 Jul 23. Review.


Understanding itch in systemic sclerosis in order to improve patient quality of life.

Frech TM, Baron M.

Clin Exp Rheumatol. 2013 Mar-Apr;31(2 Suppl 76):81-8. Epub 2013 Jul 22. Review.


Peripheral neuropathy: a complication of systemic sclerosis.

Frech TM, Smith G, Reily M, Chamberlain J, Murtaugh MA, Penrod J, Battistone MJ, Stults BM.

Clin Rheumatol. 2013 Jun;32(6):885-8. doi: 10.1007/s10067-013-2206-6. Epub 2013 Feb 13.


Nutritional status and gastrointestinal symptoms in systemic sclerosis patients.

Murtaugh MA, Frech TM.

Clin Nutr. 2013 Feb;32(1):130-5. doi: 10.1016/j.clnu.2012.06.005. Epub 2012 Jul 4.


Vascular leak is a central feature in the pathogenesis of systemic sclerosis.

Frech TM, Revelo MP, Drakos SG, Murtaugh MA, Markewitz BA, Sawitzke AD, Li DY.

J Rheumatol. 2012 Jul;39(7):1385-91. doi: 10.3899/jrheum.111380. Epub 2012 Jun 1.


The prevalence and clinical correlates of an auscultatory gap in systemic sclerosis patients.

Frech TM, Penrod J, Battistone MJ, Sawitzke AD, Stults BM.

Int J Rheumatol. 2012;2012:590845. doi: 10.1155/2012/590845. Epub 2012 Feb 16.


Probiotics for the treatment of systemic sclerosis-associated gastrointestinal bloating/ distention.

Frech TM, Khanna D, Maranian P, Frech EJ, Sawitzke AD, Murtaugh MA.

Clin Exp Rheumatol. 2011 Mar-Apr;29(2 Suppl 65):S22-5. Epub 2011 May 12.


The utility of nutraceuticals in the treatment of osteoarthritis.

Frech TM, Clegg DO.

Curr Rheumatol Rep. 2007 Apr;9(1):25-30. Review.


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