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Items: 8

1.

A comparison of the expression and metabolizing activities of phase I and II enzymes in freshly isolated human lung parenchymal cells and cryopreserved human hepatocytes.

Somers GI, Lindsay N, Lowdon BM, Jones AE, Freathy C, Ho S, Woodrooffe AJ, Bayliss MK, Manchee GR.

Drug Metab Dispos. 2007 Oct;35(10):1797-805. Epub 2007 Jul 12.

PMID:
17627976
2.

Antitumour activity of XR5944 in vitro and in vivo in combination with 5-fluorouracil and irinotecan in colon cancer cell lines.

Harris SM, Mistry P, Freathy C, Brown JL, Charlton PA.

Br J Cancer. 2005 Feb 28;92(4):722-8.

3.

Regulation of apoptosis by peroxisome proliferators.

Roberts RA, Michel C, Coyle B, Freathy C, Cain K, Boitier E.

Toxicol Lett. 2004 Apr 1;149(1-3):37-41. Review.

PMID:
15093246
4.

Design and synthesis of new templates derived from pyrrolopyrimidine as selective multidrug-resistance-associated protein inhibitors in multidrug resistance.

Wang S, Wan NC, Harrison J, Miller W, Chuckowree I, Sohal S, Hancox TC, Baker S, Folkes A, Wilson F, Thompson D, Cocks S, Farmer H, Boyce A, Freathy C, Broadbridge J, Scott J, Depledge P, Faint R, Mistry P, Charlton P.

J Med Chem. 2004 Mar 11;47(6):1339-50.

PMID:
14998324
5.

Early drug safety evaluation: biomarkers, signatures, and fingerprints.

Roberts R, Cain K, Coyle B, Freathy C, Leonard JF, Gautier JC.

Drug Metab Rev. 2003 Nov;35(4):269-75. Review.

PMID:
14705860
6.

Characterization of the transforming growth factor-beta 1-induced apoptotic transcriptome in FaO hepatoma cells.

Coyle B, Freathy C, Gant TW, Roberts RA, Cain K.

J Biol Chem. 2003 Feb 21;278(8):5920-8. Epub 2002 Dec 17.

7.

Liver toxicity and apoptosis: role of TGF-beta1, cytochrome c and the apoptosome.

Cain K, Freathy C.

Toxicol Lett. 2001 Mar 31;120(1-3):307-15. Review.

PMID:
11323189

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