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Items: 7


Mycoplasma Clearance and Risk Analysis in a Model Bioprocess: Robustness with Respect to Mycoplasma Species.

Faison T, Wang J, Johnson S, Brown M, Chiang MJ, Dolan S, Breuning C, Velugula-Yellela SR, Lute S, Fratz-Berilla EJ, Brorson K.

PDA J Pharm Sci Technol. 2019 Sep 13. pii: pdajpst.2018.009613. doi: 10.5731/pdajpst.2018.009613. [Epub ahead of print]


Impacts of intentional mycoplasma contamination on CHO cell bioreactor cultures.

Fratz-Berilla EJ, Faison T, Kohnhorst CL, Velugula-Yellela SR, Powers DN, Brorson K, Agarabi C.

Biotechnol Bioeng. 2019 Dec;116(12):3242-3252. doi: 10.1002/bit.27161. Epub 2019 Sep 11.


Real-time quantification and supplementation of bioreactor amino acids to prolong culture time and maintain antibody product quality.

Powers DN, Wang Y, Fratz-Berilla EJ, Velugula-Yellela SR, Chavez B, Angart P, Trunfio N, Yoon S, Agarabi C.

Biotechnol Prog. 2019 Nov;35(6):e2894. doi: 10.1002/btpr.2894. Epub 2019 Aug 28.


Differential effects of bioreactor process variables and purification on the human recombinant lysosomal enzyme β-glucuronidase produced from Chinese hamster ovary cells.

Parhiz H, Ketcham SA, Zou G, Ghosh B, Fratz-Berilla EJ, Ashraf M, Ju T, Madhavarao CN.

Appl Microbiol Biotechnol. 2019 Aug;103(15):6081-6095. doi: 10.1007/s00253-019-09889-7. Epub 2019 Jun 7.


Purification and Analytics of a Monoclonal Antibody from Chinese Hamster Ovary Cells Using an Automated Microbioreactor System.

Velugula-Yellela SR, Powers DN, Angart P, Faustino A, Faison T, Kohnhorst C, Fratz-Berilla EJ, Agarabi CD.

J Vis Exp. 2019 May 1;(147). doi: 10.3791/58947.


An improved purification method for the lysosomal storage disease protein β-glucuronidase produced in CHO cells.

Fratz-Berilla EJ, Ketcham SA, Parhiz H, Ashraf M, Madhavarao CN.

Protein Expr Purif. 2017 Dec;140:28-35. doi: 10.1016/j.pep.2017.07.011. Epub 2017 Jul 19.


Isoniazid inhibits human erythroid 5-aminolevulinate synthase: Molecular mechanism and tolerance study with four X-linked protoporphyria patients.

Fratz-Berilla EJ, Breydo L, Gouya L, Puy H, Uversky VN, Ferreira GC.

Biochim Biophys Acta Mol Basis Dis. 2017 Feb;1863(2):428-439. doi: 10.1016/j.bbadis.2016.11.011. Epub 2016 Nov 10.

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