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Items: 15


B-cell depletion reveals a role for antibodies in the control of chronic HIV-1 infection.

Huang KH, Bonsall D, Katzourakis A, Thomson EC, Fidler SJ, Main J, Muir D, Weber JN, Frater AJ, Phillips RE, Pybus OG, Goulder PJ, McClure MO, Cooke GS, Klenerman P.

Nat Commun. 2010 Oct 19;1:102. doi: 10.1038/ncomms1100.


HLA-associated clinical progression correlates with epitope reversion rates in early human immunodeficiency virus infection.

Duda A, Lee-Turner L, Fox J, Robinson N, Dustan S, Kaye S, Fryer H, Carrington M, McClure M, McLean AR, Fidler S, Weber J, Phillips RE, Frater AJ; SPARTAC Trial Investigators.

J Virol. 2009 Feb;83(3):1228-39. doi: 10.1128/JVI.01545-08. Epub 2008 Nov 19.


Effective T-cell responses select human immunodeficiency virus mutants and slow disease progression.

Frater AJ, Brown H, Oxenius A, G√ľnthard HF, Hirschel B, Robinson N, Leslie AJ, Payne R, Crawford H, Prendergast A, Brander C, Kiepiela P, Walker BD, Goulder PJ, McLean A, Phillips RE.

J Virol. 2007 Jun;81(12):6742-51. Epub 2007 Apr 4.


Passive sexual transmission of human immunodeficiency virus type 1 variants and adaptation in new hosts.

Frater AJ, Edwards CT, McCarthy N, Fox J, Brown H, Milicic A, Mackie N, Pillay T, Drijfhout JW, Dustan S, Clarke JR, Holmes EC, Zhang HT, Pfafferott K, Goulder PJ, McClure MO, Weber J, Phillips RE, Fidler S.

J Virol. 2006 Jul;80(14):7226-34.


Performance of two commercially available sequence-based HIV-1 genotyping systems for the detection of drug resistance against HIV type 1 group M subtypes.

Beddows S, Galpin S, Kazmi SH, Ashraf A, Johargy A, Frater AJ, White N, Braganza R, Clarke J, McClure M, Weber JN.

J Med Virol. 2003 Jul;70(3):337-42.


Mutagenically separated PCR assay for rapid detection of M41L and K70R zidovudine resistance mutations in CRF01_AE (subtype E) human immunodeficiency virus type 1.

Myint L, Ariyoshi K, Yan H, Frater AJ, Auwanit W, Pathipvanith P, Yamada K, Matsuda M, Chiba T, Fujita K, McClure M, Weber JN, Sugiura W.

Antimicrob Agents Chemother. 2002 Dec;46(12):3861-8.


Comparative response of African HIV-1-infected individuals to highly active antiretroviral therapy.

Frater AJ, Dunn DT, Beardall AJ, Ariyoshi K, Clarke JR, McClure MO, Weber JN.

AIDS. 2002 May 24;16(8):1139-46.


Adenovirus-mediated overexpression of extracellular superoxide dismutase improves endothelial dysfunction in a rat model of hypertension.

Fennell JP, Brosnan MJ, Frater AJ, Hamilton CA, Alexander MY, Nicklin SA, Heistad DD, Baker AH, Dominiczak AF.

Gene Ther. 2002 Jan;9(2):110-7.


Differential susceptibility of retroviruses to nucleoside analogues.

Rosenblum LL, Patton G, Grigg AR, Frater AJ, Cain D, Erlwein O, Hill CL, Clarke JR, McClure MO.

Antivir Chem Chemother. 2001 Mar;12(2):91-7.


Impact of baseline polymorphisms in RT and protease on outcome of highly active antiretroviral therapy in HIV-1-infected African patients.

Frater AJ, Beardall A, Ariyoshi K, Churchill D, Galpin S, Clarke JR, Weber JN, McClure MO.

AIDS. 2001 Aug 17;15(12):1493-502.


Simple detection of point mutations associated with HIV-1 drug resistance.

Frater AJ, Chaput CC, Beddows S, Weber JN, McClure MO.

J Virol Methods. 2001 Apr;93(1-2):145-56.


HIV-1 resistance genotyping by sequencing produces inconsistent results for mixed viral populations.

Frater AJ, Chaput CC, Weber JN, McClure MO.

AIDS. 2000 Jul 7;14(10):1473-5. No abstract available.


Glutamic acid decarboxylase T lymphocyte responses associated with susceptibility or resistance to type I diabetes: analysis in disease discordant human twins, non-obese diabetic mice and HLA-DQ transgenic mice.

Boyton RJ, Lohmann T, Londei M, Kalbacher H, Halder T, Frater AJ, Douek DC, Leslie DG, Flavell RA, Altmann DM.

Int Immunol. 1998 Dec;10(12):1765-76.


Immune responsiveness in mutant mice lacking T-cell receptor alpha beta+ cells.

Chandler P, Frater AJ, Douek DC, Viney JL, Kay G, Owen MJ, Hayday AC, Simpson E, Altmann DM.

Immunology. 1995 Aug;85(4):531-7.


The T cell response of HLA-DR transgenic mice to human myelin basic protein and other antigens in the presence and absence of human CD4.

Altmann DM, Douek DC, Frater AJ, Hetherington CM, Inoko H, Elliott JI.

J Exp Med. 1995 Mar 1;181(3):867-75.

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