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Items: 1 to 50 of 125

1.

Metabolomics should be deployed in identification and characterization of gene-edited crops.

Fraser PD, Aharoni A, Hall RD, Huang S, Giovannoni JJ, Sonnewald U, Fernie AR.

Plant J. 2020 Jan 10. doi: 10.1111/tpj.14679. [Epub ahead of print]

PMID:
31923321
2.

Metabolite database for root, tuber and banana crops to facilitate modern breeding in understudied crops.

Price EJ, Drapal M, Perez-Fons L, Amah D, Bhattacharjee R, Heider B, Rouard M, Swennen R, Becerra Lopez-Lavalle LA, Fraser PD.

Plant J. 2019 Dec 17. doi: 10.1111/tpj.14649. [Epub ahead of print]

PMID:
31845400
3.

Cassava Metabolomics and Starch Quality.

Rosado-Souza L, David LC, Drapal M, Fraser PD, Hofmann J, Klemens PAW, Ludewig F, Neuhaus HE, Obata T, Perez-Fons L, Schlereth A, Sonnewald U, Stitt M, Zeeman SC, Zierer W, Fernie AR.

Curr Protoc Plant Biol. 2019 Dec;4(4):e20102. doi: 10.1002/cppb.20102.

PMID:
31834991
4.

A metabolomics characterisation of natural variation in the resistance of cassava to whitefly.

Perez-Fons L, Bohorquez-Chaux A, Irigoyen ML, Garceau DC, Morreel K, Boerjan W, Walling LL, Becerra Lopez-Lavalle LA, Fraser PD.

BMC Plant Biol. 2019 Nov 27;19(1):518. doi: 10.1186/s12870-019-2107-1.

5.

The subcellular localization of two isopentenyl diphosphate isomerases in rice suggests a role for the endoplasmic reticulum in isoprenoid biosynthesis.

Jin X, Baysal C, Gao L, Medina V, Drapal M, Ni X, Sheng Y, Shi L, Capell T, Fraser PD, Christou P, Zhu C.

Plant Cell Rep. 2020 Jan;39(1):119-133. doi: 10.1007/s00299-019-02479-x. Epub 2019 Nov 2.

PMID:
31679061
6.

Determination of carotenoids in sweet potato (Ipomoea batatas L., Lam) tubers: Implications for accurate provitamin A determination in staple sturdy tuber crops.

Drapal M, Fraser PD.

Phytochemistry. 2019 Nov;167:112102. doi: 10.1016/j.phytochem.2019.112102. Epub 2019 Aug 26.

PMID:
31466009
7.

Metabolite Profiling: A Tool for the Biochemical Characterisation of Mycobacterium sp.

Drapal M, Fraser PD.

Microorganisms. 2019 May 25;7(5). pii: E148. doi: 10.3390/microorganisms7050148. Review.

8.

Natural Variation in CCD4 Promoter Underpins Species-Specific Evolution of Red Coloration in Citrus Peel.

Zheng X, Zhu K, Sun Q, Zhang W, Wang X, Cao H, Tan M, Xie Z, Zeng Y, Ye J, Chai L, Xu Q, Pan Z, Xiao S, Fraser PD, Deng X.

Mol Plant. 2019 Sep 2;12(9):1294-1307. doi: 10.1016/j.molp.2019.04.014. Epub 2019 May 16.

PMID:
31102783
9.

Metabolite profiling characterises chemotypes of Musa diploids and triploids at juvenile and pre-flowering growth stages.

Drapal M, de Carvalho EB, Rouard M, Amah D, Sardos J, Van den Houwe I, Brown A, Roux N, Swennen R, Fraser PD.

Sci Rep. 2019 Mar 15;9(1):4657. doi: 10.1038/s41598-019-41037-z.

10.

Carotenoid biosynthesis and sequestration in red chilli pepper fruit and its impact on colour intensity traits.

Berry HM, Rickett DV, Baxter CJ, Enfissi EMA, Fraser PD.

J Exp Bot. 2019 May 9;70(10):2637-2650. doi: 10.1093/jxb/erz086.

11.

The road to astaxanthin production in tomato fruit reveals plastid and metabolic adaptation resulting in an unintended high lycopene genotype with delayed over-ripening properties.

Enfissi EMA, Nogueira M, D'Ambrosio C, Stigliani AL, Giorio G, Misawa N, Fraser PD.

Plant Biotechnol J. 2019 Aug;17(8):1501-1513. doi: 10.1111/pbi.13073. Epub 2019 Feb 1.

12.

Metabolic diversity in sweet potato (Ipomoea batatas, Lam.) leaves and storage roots.

Drapal M, Rossel G, Heider B, Fraser PD.

Hortic Res. 2019 Jan 1;6:2. doi: 10.1038/s41438-018-0075-5. eCollection 2019.

13.

SLAF-Based Construction of a High-Density Genetic Map and Its Application in QTL Mapping of Carotenoids Content in Citrus Fruit.

Zheng X, Tang Y, Ye J, Pan Z, Tan M, Xie Z, Chai L, Xu Q, Fraser PD, Deng X.

J Agric Food Chem. 2019 Jan 23;67(3):994-1002. doi: 10.1021/acs.jafc.8b05176. Epub 2019 Jan 10.

PMID:
30589260
14.

Construction of a fusion enzyme for astaxanthin formation and its characterisation in microbial and plant hosts: A new tool for engineering ketocarotenoids.

Nogueira M, Enfissi EMA, Welsch R, Beyer P, Zurbriggen MD, Fraser PD.

Metab Eng. 2019 Mar;52:243-252. doi: 10.1016/j.ymben.2018.12.006. Epub 2018 Dec 20.

15.

Capturing Biochemical Diversity in Cassava ( Manihot esculenta Crantz) through the Application of Metabolite Profiling.

Drapal M, Barros de Carvalho E, Ovalle Rivera TM, Becerra Lopez-Lavalle LA, Fraser PD.

J Agric Food Chem. 2019 Jan 23;67(3):986-993. doi: 10.1021/acs.jafc.8b04769. Epub 2019 Jan 9.

16.

Characterization of CRISPR Mutants Targeting Genes Modulating Pectin Degradation in Ripening Tomato.

Wang D, Samsulrizal NH, Yan C, Allcock NS, Craigon J, Blanco-Ulate B, Ortega-Salazar I, Marcus SE, Bagheri HM, Perez Fons L, Fraser PD, Foster T, Fray R, Knox JP, Seymour GB.

Plant Physiol. 2019 Feb;179(2):544-557. doi: 10.1104/pp.18.01187. Epub 2018 Nov 20.

17.

Effect of diflufenican on total carotenoid and phytoene production in carrot suspension-cultured cells.

Miras-Moreno B, Pedreño MA, Fraser PD, Sabater-Jara AB, Almagro L.

Planta. 2019 Jan;249(1):113-122. doi: 10.1007/s00425-018-2966-y. Epub 2018 Aug 6.

PMID:
30083808
18.

The assessment of changes to the nontuberculous mycobacterial metabolome in response to anti-TB drugs.

Drapal M, Wheeler PR, Fraser PD.

FEMS Microbiol Lett. 2018 Aug 1;365(15). doi: 10.1093/femsle/fny153.

PMID:
29945244
19.

Carotenoid profiling of yams: Clarity, comparisons and diversity.

Price EJ, Bhattacharjee R, Lopez-Montes A, Fraser PD.

Food Chem. 2018 Sep 1;259:130-138. doi: 10.1016/j.foodchem.2018.03.066. Epub 2018 Mar 27.

PMID:
29680035
20.
21.

Detection and Enhancement of Ketocarotenoid Accumulation in the Newly Isolated Sarcinoid Green Microalga Chlorosarcinopsis PY02.

Cherdchukeattisak P, Fraser PD, Purton S, Brocklehurst TW.

Biology (Basel). 2018 Feb 12;7(1). pii: E17. doi: 10.3390/biology7010017.

22.

Metabolite profiling of yam (Dioscorea spp.) accessions for use in crop improvement programmes.

Price EJ, Bhattacharjee R, Lopez-Montes A, Fraser PD.

Metabolomics. 2017;13(11):144. doi: 10.1007/s11306-017-1279-7. Epub 2017 Oct 14.

23.

Engineering of tomato for the sustainable production of ketocarotenoids and its evaluation in aquaculture feed.

Nogueira M, Enfissi EMA, Martínez Valenzuela ME, Menard GN, Driller RL, Eastmond PJ, Schuch W, Sandmann G, Fraser PD.

Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):10876-10881. doi: 10.1073/pnas.1708349114. Epub 2017 Sep 25.

24.

Creating plant molecular factories for industrial and nutritional isoprenoid production.

Nogueira M, Enfissi EM, Almeida J, Fraser PD.

Curr Opin Biotechnol. 2018 Feb;49:80-87. doi: 10.1016/j.copbio.2017.08.002. Epub 2017 Aug 29. Review.

PMID:
28837945
25.

The Formation and Sequestration of Nonendogenous Ketocarotenoids in Transgenic Nicotiana glauca.

Mortimer CL, Misawa N, Perez-Fons L, Robertson FP, Harada H, Bramley PM, Fraser PD.

Plant Physiol. 2017 Mar;173(3):1617-1635. doi: 10.1104/pp.16.01297. Epub 2017 Jan 30.

26.

Identification of metabolites associated with water stress responses in Solanum tuberosum L. clones.

Drapal M, Farfan-Vignolo ER, Gutierrez OR, Bonierbale M, Mihovilovich E, Fraser PD.

Phytochemistry. 2017 Mar;135:24-33. doi: 10.1016/j.phytochem.2016.12.003. Epub 2016 Dec 10.

PMID:
27964835
27.

The regulation of carotenoid formation in tomato fruit.

Enfissi EM, Nogueira M, Bramley PM, Fraser PD.

Plant J. 2017 Feb;89(4):774-788. doi: 10.1111/tpj.13428. Epub 2017 Feb 7.

28.

Rapid identification of causal mutations in tomato EMS populations via mapping-by-sequencing.

Garcia V, Bres C, Just D, Fernandez L, Tai FW, Mauxion JP, Le Paslier MC, Bérard A, Brunel D, Aoki K, Alseekh S, Fernie AR, Fraser PD, Rothan C.

Nat Protoc. 2016 Dec;11(12):2401-2418. doi: 10.1038/nprot.2016.143. Epub 2016 Nov 3.

PMID:
27809315
29.

Corrigendum: Genetic improvement of tomato by targeted control of fruit softening.

Uluisik S, Chapman NH, Smith R, Poole M, Adams G, Gillis RB, Besong TM, Sheldon J, Stiegelmeyer S, Perez L, Samsulrizal N, Wang D, Fisk ID, Yang N, Baxter C, Rickett D, Fray R, Blanco-Ulate B, Powell AL, Harding SE, Craigon J, Rose JK, Fich EA, Sun L, Domozych DS, Fraser PD, Tucker GA, Grierson D, Seymour GB.

Nat Biotechnol. 2016 Oct 11;34(10):1072. doi: 10.1038/nbt1016-1072d. No abstract available.

PMID:
27727231
30.

Metabolite profiling of Phycomyces blakesleeanus carotene mutants reveals global changes across intermediary metabolism.

Alcalde E, Fraser PD.

Microbiology. 2016 Nov;162(11):1963-1971. doi: 10.1099/mic.0.000376. Epub 2016 Oct 4.

PMID:
27707428
31.

Engineered maize as a source of astaxanthin: processing and application as fish feed.

Breitenbach J, Nogueira M, Farré G, Zhu C, Capell T, Christou P, Fleck G, Focken U, Fraser PD, Sandmann G.

Transgenic Res. 2016 Dec;25(6):785-793. Epub 2016 Aug 12.

PMID:
27520497
32.

Genetic modification of tomato with the tobacco lycopene β-cyclase gene produces high β-carotene and lycopene fruit.

Ralley L, Schuch W, Fraser PD, Bramley PM.

Z Naturforsch C J Biosci. 2016 Sep 1;71(9-10):295-301. doi: 10.1515/znc-2016-0102.

PMID:
27487494
33.

Genetic improvement of tomato by targeted control of fruit softening.

Uluisik S, Chapman NH, Smith R, Poole M, Adams G, Gillis RB, Besong TM, Sheldon J, Stiegelmeyer S, Perez L, Samsulrizal N, Wang D, Fisk ID, Yang N, Baxter C, Rickett D, Fray R, Blanco-Ulate B, Powell AL, Harding SE, Craigon J, Rose JK, Fich EA, Sun L, Domozych DS, Fraser PD, Tucker GA, Grierson D, Seymour GB.

Nat Biotechnol. 2016 Sep;34(9):950-2. doi: 10.1038/nbt.3602. Epub 2016 Jul 25.

PMID:
27454737
34.

Antioxidant compounds and their bioaccessibility in tomato fruit and puree obtained from a DETIOLATED-1 (DET-1) down-regulated genetically modified genotype.

Talens P, Mora L, Bramley PM, Fraser PD.

Food Chem. 2016 Dec 15;213:735-741. doi: 10.1016/j.foodchem.2016.06.079. Epub 2016 Jun 23.

PMID:
27451242
35.

Metabolite profiling of Dioscorea (yam) species reveals underutilised biodiversity and renewable sources for high-value compounds.

Price EJ, Wilkin P, Sarasan V, Fraser PD.

Sci Rep. 2016 Jul 7;6:29136. doi: 10.1038/srep29136.

36.

Metabolite analysis of Mycobacterium species under aerobic and hypoxic conditions reveals common metabolic traits.

Drapal M, Wheeler PR, Fraser PD.

Microbiology. 2016 Aug;162(8):1456-1467. doi: 10.1099/mic.0.000325. Epub 2016 Jun 15.

PMID:
27312482
37.

Metabolic engineering of astaxanthin biosynthesis in maize endosperm and characterization of a prototype high oil hybrid.

Farré G, Perez-Fons L, Decourcelle M, Breitenbach J, Hem S, Zhu C, Capell T, Christou P, Fraser PD, Sandmann G.

Transgenic Res. 2016 Aug;25(4):477-89. doi: 10.1007/s11248-016-9943-7. Epub 2016 Mar 1.

PMID:
26931320
38.

Standards for plant synthetic biology: a common syntax for exchange of DNA parts.

Patron NJ, Orzaez D, Marillonnet S, Warzecha H, Matthewman C, Youles M, Raitskin O, Leveau A, Farré G, Rogers C, Smith A, Hibberd J, Webb AA, Locke J, Schornack S, Ajioka J, Baulcombe DC, Zipfel C, Kamoun S, Jones JD, Kuhn H, Robatzek S, Van Esse HP, Sanders D, Oldroyd G, Martin C, Field R, O'Connor S, Fox S, Wulff B, Miller B, Breakspear A, Radhakrishnan G, Delaux PM, Loqué D, Granell A, Tissier A, Shih P, Brutnell TP, Quick WP, Rischer H, Fraser PD, Aharoni A, Raines C, South PF, Ané JM, Hamberger BR, Langdale J, Stougaard J, Bouwmeester H, Udvardi M, Murray JA, Ntoukakis V, Schäfer P, Denby K, Edwards KJ, Osbourn A, Haseloff J.

New Phytol. 2015 Oct;208(1):13-9. doi: 10.1111/nph.13532. Epub 2015 Jul 14. Erratum in: New Phytol. 2016 Jan;209(2):885.

39.

Product stability and sequestration mechanisms in Solanum tuberosum engineered to biosynthesize high value ketocarotenoids.

Mortimer CL, Misawa N, Ducreux L, Campbell R, Bramley PM, Taylor M, Fraser PD.

Plant Biotechnol J. 2016 Jan;14(1):140-52. doi: 10.1111/pbi.12365. Epub 2015 Apr 2.

40.

Optimising ketocarotenoid production in potato tubers: effect of genetic background, transgene combinations and environment.

Campbell R, Morris WL, Mortimer CL, Misawa N, Ducreux LJ, Morris JA, Hedley PE, Fraser PD, Taylor MA.

Plant Sci. 2015 May;234:27-37. doi: 10.1016/j.plantsci.2015.01.014. Epub 2015 Feb 7.

PMID:
25804807
41.

Annotation and functional assignment of the genes for the C30 carotenoid pathways from the genomes of two bacteria: Bacillus indicus and Bacillus firmus.

Steiger S, Perez-Fons L, Cutting SM, Fraser PD, Sandmann G.

Microbiology. 2015 Jan;161(Pt 1):194-202. doi: 10.1099/mic.0.083519-0. Epub 2014 Oct 17.

PMID:
25326460
42.

The application of metabolite profiling to Mycobacterium spp.: determination of metabolite changes associated with growth.

Drapal M, Perez-Fons L, Wheeler PR, Fraser PD.

J Microbiol Methods. 2014 Nov;106:23-32. doi: 10.1016/j.mimet.2014.07.037. Epub 2014 Aug 7.

PMID:
25108291
43.

Transcript and metabolite profiling for the evaluation of tobacco tree and poplar as feedstock for the bio-based industry.

Ruprecht C, Tohge T, Fernie A, Mortimer CL, Kozlo A, Fraser PD, Funke N, Cesarino I, Vanholme R, Boerjan W, Morreel K, Burgert I, Gierlinger N, Bulone V, Schneider V, Stockero A, Navarro-Aviñó J, Pudel F, Tambuyser B, Hygate J, Bumstead J, Notley L, Persson S.

J Vis Exp. 2014 May 16;(87). doi: 10.3791/51393. Erratum in: J Vis Exp. 2016 Jun 30;(112):. [Corrected from Navarro, Juan Pedro] [Corrected to Navarro-Aviñó, Juan.].

44.

Natural products – learning chemistry from plants.

Staniek A, Bouwmeester H, Fraser PD, Kayser O, Martens S, Tissier A, van der Krol S, Wessjohann L, Warzecha H.

Biotechnol J. 2014 Mar;9(3):326-36. doi: 10.1002/biot.201300059. Review.

PMID:
24677691
45.

A genome-wide metabolomic resource for tomato fruit from Solanum pennellii.

Perez-Fons L, Wells T, Corol DI, Ward JL, Gerrish C, Beale MH, Seymour GB, Bramley PM, Fraser PD.

Sci Rep. 2014 Jan 24;4:3859. doi: 10.1038/srep03859.

46.

Degradation of LIM domain-binding protein three during processing of Spanish dry-cured ham.

Gallego M, Mora L, Fraser PD, Aristoy MC, Toldrá F.

Food Chem. 2014 Apr 15;149:121-8. doi: 10.1016/j.foodchem.2013.10.076. Epub 2013 Oct 25.

PMID:
24295685
47.

Subchromoplast sequestration of carotenoids affects regulatory mechanisms in tomato lines expressing different carotenoid gene combinations.

Nogueira M, Mora L, Enfissi EM, Bramley PM, Fraser PD.

Plant Cell. 2013 Nov;25(11):4560-79. doi: 10.1105/tpc.113.116210. Epub 2013 Nov 18.

48.

Natural products - modifying metabolite pathways in plants.

Staniek A, Bouwmeester H, Fraser PD, Kayser O, Martens S, Tissier A, van der Krol S, Wessjohann L, Warzecha H.

Biotechnol J. 2013 Oct;8(10):1159-71. doi: 10.1002/biot.201300224. Epub 2013 Sep 17. Review.

PMID:
24092673
49.

Development and optimisation of a label-free quantitative proteomic procedure and its application in the assessment of genetically modified tomato fruit.

Mora L, Bramley PM, Fraser PD.

Proteomics. 2013 Jun;13(12-13):2016-30. doi: 10.1002/pmic.201200480.

PMID:
23616442
50.

Carotenoids and tocopherols in yellow and red raspberries.

Carvalho E, Fraser PD, Martens S.

Food Chem. 2013 Aug 15;139(1-4):744-52. doi: 10.1016/j.foodchem.2012.12.047. Epub 2013 Jan 16.

PMID:
23561169

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