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Items: 1 to 50 of 124

1.

Antiviral Hammerhead Ribozymes Are Effective for Developing Transgenic Suppression of Chikungunya Virus in Aedes aegypti Mosquitoes.

Mishra P, Furey C, Balaraman V, Fraser MJ.

Viruses. 2016 Jun 10;8(6). pii: E163. doi: 10.3390/v8060163.

2.

Suppression of the Arboviruses Dengue and Chikungunya Using a Dual-Acting Group-I Intron Coupled with Conditional Expression of the Bax C-Terminal Domain.

Carter JR, Taylor S, Fraser TS, Kucharski CA, Dawson JL, Fraser MJ Jr.

PLoS One. 2015 Nov 18;10(11):e0139899. doi: 10.1371/journal.pone.0139899. eCollection 2015.

3.

Targeted glycoengineering extends the protein N-glycosylation pathway in the silkworm silk gland.

Mabashi-Asazuma H, Sohn BH, Kim YS, Kuo CW, Khoo KH, Kucharski CA, Fraser MJ Jr, Jarvis DL.

Insect Biochem Mol Biol. 2015 Oct;65:20-7. doi: 10.1016/j.ibmb.2015.07.004. Epub 2015 Jul 8.

4.

Disruption of dengue virus transmission by mosquitoes.

Franz AW, Balaraman V, Fraser MJ Jr.

Curr Opin Insect Sci. 2015 Apr 1;8:88-96.

5.

Trans-splicing group I intron targeting hepatitis C virus IRES mediates cell death upon viral infection in Huh7.5 cells.

Nawtaisong P, Fraser ME, Carter JR, Fraser MJ Jr.

Virology. 2015 Jul;481:223-34. doi: 10.1016/j.virol.2015.02.023. Epub 2015 Apr 7.

6.

Effective suppression of dengue virus using a novel group-I intron that induces apoptotic cell death upon infection through conditional expression of the Bax C-terminal domain.

Carter JR, Keith JH, Fraser TS, Dawson JL, Kucharski CA, Horne KM, Higgs S, Fraser MJ Jr.

Virol J. 2014 Jun 13;11:111. doi: 10.1186/1743-422X-11-111.

7.

Design and analysis of hammerhead ribozyme activity against an artificial gene target.

Carter JR, Nawtaisong P, Balaraman V, Fraser MJ Jr.

Methods Mol Biol. 2014;1103:57-66. doi: 10.1007/978-1-62703-730-3_5.

8.

A novel dengue virus detection method that couples DNAzyme and gold nanoparticle approaches.

Carter JR, Balaraman V, Kucharski CA, Fraser TS, Fraser MJ Jr.

Virol J. 2013 Jun 28;10:201. doi: 10.1186/1743-422X-10-201.

9.

Steroidogenic enzyme expression in the human fetal liver and potential role in the endocrinology of pregnancy.

O'Shaughnessy PJ, Monteiro A, Bhattacharya S, Fraser MJ, Fowler PA.

Mol Hum Reprod. 2013 Mar;19(3):177-87. doi: 10.1093/molehr/gas059. Epub 2012 Nov 29.

PMID:
23197595
10.

Silkworms transformed with chimeric silkworm/spider silk genes spin composite silk fibers with improved mechanical properties.

Teulé F, Miao YG, Sohn BH, Kim YS, Hull JJ, Fraser MJ Jr, Lewis RV, Jarvis DL.

Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):923-8. doi: 10.1073/pnas.1109420109. Epub 2012 Jan 3.

11.

Insect transgenesis: current applications and future prospects.

Fraser MJ Jr.

Annu Rev Entomol. 2012;57:267-89. doi: 10.1146/annurev.ento.54.110807.090545. Review.

PMID:
22149266
12.

Targeting of highly conserved Dengue virus sequences with anti-Dengue virus trans-splicing group I introns.

Carter JR, Keith JH, Barde PV, Fraser TS, Fraser MJ Jr.

BMC Mol Biol. 2010 Nov 15;11:84. doi: 10.1186/1471-2199-11-84.

13.

Intramolecular integration assay validates integrase phi C31 and R4 potential in a variety of insect cells.

Chompoosri J, Fraser T, Rongsriyam Y, Komalamisra N, Siriyasatien P, Thavara U, Tawatsin A, Fraser MJ Jr.

Southeast Asian J Trop Med Public Health. 2009 Nov;40(6):1235-53.

PMID:
20578458
14.

Use of the piggyBac transposon to create HIV-1 gag transgenic insect cell lines for continuous VLP production.

Lynch AG, Tanzer F, Fraser MJ, Shephard EG, Williamson AL, Rybicki EP.

BMC Biotechnol. 2010 Mar 31;10:30. doi: 10.1186/1472-6750-10-30.

15.

Effective suppression of Dengue fever virus in mosquito cell cultures using retroviral transduction of hammerhead ribozymes targeting the viral genome.

Nawtaisong P, Keith J, Fraser T, Balaraman V, Kolokoltsov A, Davey RA, Higgs S, Mohammed A, Rongsriyam Y, Komalamisra N, Fraser MJ Jr.

Virol J. 2009 Jun 4;6:73. doi: 10.1186/1743-422X-6-73.

16.

piggyBac is an effective tool for functional analysis of the Plasmodium falciparum genome.

Balu B, Chauhan C, Maher SP, Shoue DA, Kissinger JC, Fraser MJ Jr, Adams JH.

BMC Microbiol. 2009 May 7;9:83. doi: 10.1186/1471-2180-9-83.

17.

Examining the relative activity of several dicistrovirus intergenic internal ribosome entry site elements in uninfected insect and mammalian cell lines.

Carter JR, Fraser TS, Fraser MJ Jr.

J Gen Virol. 2008 Dec;89(Pt 12):3150-5. doi: 10.1099/vir.0.2008/003921-0.

PMID:
19008405
18.

Rebound of a coal tar creosote plume following partial source zone treatment with permanganate.

Thomson NR, Fraser MJ, Lamarche C, Barker JF, Forsey SP.

J Contam Hydrol. 2008 Nov 14;102(1-2):154-71. doi: 10.1016/j.jconhyd.2008.07.001. Epub 2008 Jul 11.

PMID:
18757111
19.

Mutational analysis of highly conserved aspartate residues essential to the catalytic core of the piggyBac transposase.

Keith JH, Schaeper CA, Fraser TS, Fraser MJ Jr.

BMC Mol Biol. 2008 Aug 11;9:73. doi: 10.1186/1471-2199-9-73.

20.

Analysis of the piggyBac transposase reveals a functional nuclear targeting signal in the 94 c-terminal residues.

Keith JH, Fraser TS, Fraser MJ Jr.

BMC Mol Biol. 2008 Aug 11;9:72. doi: 10.1186/1471-2199-9-72.

21.

Post-integration stability of piggyBac in Aedes aegypti.

Sethuraman N, Fraser MJ Jr, Eggleston P, O'Brochta DA.

Insect Biochem Mol Biol. 2007 Sep;37(9):941-51. Epub 2007 May 17.

22.

piggyBac transposon mediated transgenesis of the human blood fluke, Schistosoma mansoni.

Morales ME, Mann VH, Kines KJ, Gobert GN, Fraser MJ Jr, Kalinna BH, Correnti JM, Pearce EJ, Brindley PJ.

FASEB J. 2007 Nov;21(13):3479-89. Epub 2007 Jun 22.

PMID:
17586730
23.

High efficiency germ-line transformation of mosquitoes.

Lobo NF, Clayton JR, Fraser MJ, Kafatos FC, Collins FH.

Nat Protoc. 2006;1(3):1312-7.

PMID:
17406416
24.

Active integration: new strategies for transgenesis.

Shinohara ET, Kaminski JM, Segal DJ, Pelczar P, Kolhe R, Ryan T, Coates CJ, Fraser MJ, Handler AM, Yanagimachi R, Moisyadi S.

Transgenic Res. 2007 Jun;16(3):333-9. Epub 2007 Mar 6.

26.

Interplasmid transposition demonstrates piggyBac mobility in vertebrate species.

Lobo NF, Fraser TS, Adams JA, Fraser MJ Jr.

Genetica. 2006 Sep-Nov;128(1-3):347-57.

PMID:
17028963
27.

High-efficiency transformation of Plasmodium falciparum by the lepidopteran transposable element piggyBac.

Balu B, Shoue DA, Fraser MJ Jr, Adams JH.

Proc Natl Acad Sci U S A. 2005 Nov 8;102(45):16391-6. Epub 2005 Oct 31.

28.

piggyBac internal sequences are necessary for efficient transformation of target genomes.

Li X, Harrell RA, Handler AM, Beam T, Hennessy K, Fraser MJ Jr.

Insect Mol Biol. 2005 Jan;14(1):17-30.

PMID:
15663772
29.

An investigation of a possible role for mitochondrial nuclease in apoptosis.

Meng XW, Fraser MJ, Ireland CM, Feller JM, Ziegler JB.

Apoptosis. 1998 Dec;3(6):395-405.

PMID:
14646472
30.

Molecular evolutionary analysis of the widespread piggyBac transposon family and related "domesticated" sequences.

Sarkar A, Sim C, Hong YS, Hogan JR, Fraser MJ, Robertson HM, Collins FH.

Mol Genet Genomics. 2003 Nov;270(2):173-80. Epub 2003 Aug 29.

PMID:
12955498
31.

Germ line transformation of the yellow fever mosquito, Aedes aegypti, mediated by transpositional insertion of a piggyBac vector.

Lobo NF, Hua-Van A, Li X, Nolen BM, Fraser MJ Jr.

Insect Mol Biol. 2002 Apr;11(2):133-9.

PMID:
11966878
32.

The minimum internal and external sequence requirements for transposition of the eukaryotic transformation vector piggyBac.

Li X, Lobo N, Bauser CA, Fraser MJ Jr.

Mol Genet Genomics. 2001 Oct;266(2):190-8.

PMID:
11683259
33.
34.

Caspase-3-dependent and caspase-3-independent pathways leading to chromatin DNA fragmentation in HL-60 cells.

Meng XW, Fraser MJ, Feller JM, Ziegler JB.

Apoptosis. 2000 Feb;5(1):61-7.

PMID:
11227493
35.

Caspase-3 activates endo-exonuclease: further evidence for a role of the nuclease in apoptosis.

Meng XW, Fraser MJ, Feller JM, Ziegler JB.

Apoptosis. 2000 Jun;5(3):243-54.

PMID:
11225846
36.

The piggyBac element is capable of precise excision and transposition in cells and embryos of the mosquito, Anopheles gambiae.

Grossman GL, Rafferty CS, Fraser MJ, Benedict MQ.

Insect Biochem Mol Biol. 2000 Oct;30(10):909-14. Erratum in: Insect Biochem Mol Biol 2002 Apr;32(4):487.

PMID:
10899457
37.
38.
39.

Isolation and characterization of LMC, a novel lymphocyte and monocyte chemoattractant human CC chemokine, with myelosuppressive activity.

Youn BS, Zhang S, Broxmeyer HE, Antol K, Fraser MJ Jr, Hangoc G, Kwon BS.

Biochem Biophys Res Commun. 1998 Jun 18;247(2):217-22.

PMID:
9642106
40.

The lepidopteran transposon vector, piggyBac, mediates germ-line transformation in the Mediterranean fruit fly.

Handler AM, McCombs SD, Fraser MJ, Saul SH.

Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7520-5.

41.

Analysis of the cis-acting DNA elements required for piggyBac transposable element excision.

Elick TA, Lobo N, Fraser MJ Jr.

Mol Gen Genet. 1997 Aug;255(6):605-10.

PMID:
9323364
42.

Endo-exonuclease of human leukaemic cells: evidence for a role in apoptosis.

Fraser MJ, Tynan SJ, Papaioannou A, Ireland CM, Pittman SM.

J Cell Sci. 1996 Sep;109 ( Pt 9):2343-60.

45.
47.

A novel chemokine, macrophage inflammatory protein-related protein-2, inhibits colony formation of bone marrow myeloid progenitors.

Youn BS, Jang IK, Broxmeyer HE, Cooper S, Jenkins NA, Gilbert DJ, Copeland NG, Elick TA, Fraser MJ Jr, Kwon BS.

J Immunol. 1995 Sep 1;155(5):2661-7.

PMID:
7650394
48.

Assay for movement of Lepidopteran transposon IFP2 in insect cells using a baculovirus genome as a target DNA.

Fraser MJ, Cary L, Boonvisudhi K, Wang HG.

Virology. 1995 Aug 20;211(2):397-407.

49.

Endo-exonucleases: enzymes involved in DNA repair and cell death?

Fraser MJ.

Bioessays. 1994 Oct;16(10):761-6. Review.

PMID:
7980480
50.

Cloning and sequence analysis of a p40 structural protein gene of Helicoverpa zea nuclear polyhedrosis virus.

Ma SW, Corsaro BG, Klebba PE, Fraser MJ.

Virology. 1993 Jan;192(1):224-33.

PMID:
8517018

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