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Humulene Diepoxides from the Australian Arid Zone Herb Dysphania: Assignment of Aged Hops Constituents.

Tan YP, Agnew-Francis KA, Hofmann J, Savchenko AI, Lafontaine SR, Boyle GM, Bernhardt PV, Fraser JA, Shellhammer TH, Williams CM.

Chemistry. 2020 Feb 3;26(7):1653-1660. doi: 10.1002/chem.201904420. Epub 2020 Jan 21.


hASH1 nuclear localization persists in neuroendocrine transdifferentiated prostate cancer cells, even upon reintroduction of androgen.

Fraser JA, Sutton JE, Tazayoni S, Bruce I, Poole AV.

Sci Rep. 2019 Dec 13;9(1):19076. doi: 10.1038/s41598-019-55665-y.


Regulatory Mechanism of the Atypical AP-1-Like Transcription Factor Yap1 in Cryptococcus neoformans.

So YS, Maeng S, Yang DH, Kim H, Lee KT, Yu SR, Tenor JL, Giri VK, Toffaletti DL, Arras S, Fraser JA, Perfect JR, Bahn YS.

mSphere. 2019 Nov 20;4(6). pii: e00785-19. doi: 10.1128/mSphere.00785-19.


amdS as a dominant recyclable marker in Cryptococcus neoformans.

Erpf PE, Stephenson CJ, Fraser JA.

Fungal Genet Biol. 2019 Oct;131:103241. doi: 10.1016/j.fgb.2019.103241. Epub 2019 Jun 17.


A Comparison of Stool Enteropathogen Detection by Semiquantitative PCR in Adults With Acute Travelers' Diarrhea Before and 3 Weeks After Successful Antibiotic Treatment.

Tisdale MD, Tribble DR, Telu K, Fraser JA, Connor P, Philip C, Odundo E, Reyes F, Simons MP, Swierczewski B, Lizewski S, Liu J, Houpt E, Riddle MS, Lalani T.

Open Forum Infect Dis. 2019 Apr 26;6(5):ofz187. doi: 10.1093/ofid/ofz187. eCollection 2019 May.


MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.

Coll RC, Hill JR, Day CJ, Zamoshnikova A, Boucher D, Massey NL, Chitty JL, Fraser JA, Jennings MP, Robertson AAB, Schroder K.

Nat Chem Biol. 2019 Jun;15(6):556-559. doi: 10.1038/s41589-019-0277-7. Epub 2019 May 13.


Ion channel gating in cardiac ryanodine receptors from the arrhythmic RyR2-P2328S mouse.

Salvage SC, Gallant EM, Beard NA, Ahmad S, Valli H, Fraser JA, Huang CL, Dulhunty AF.

J Cell Sci. 2019 May 21;132(10). pii: jcs229039. doi: 10.1242/jcs.229039.


Severe sequential visual loss in MS co-diagnosis of Leber's hereditary optic neuropathy.

Riccio PM, Fraser JA, Lee DH, Morrow SA.

Can J Ophthalmol. 2019 Apr;54(2):e69-e70. doi: 10.1016/j.jcjo.2018.06.020. Epub 2018 Aug 30. No abstract available.


The application of Lempel-Ziv and Titchener complexity analysis for equine telemetric electrocardiographic recordings.

Alexeenko V, Fraser JA, Dolgoborodov A, Bowen M, Huang CL, Marr CM, Jeevaratnam K.

Sci Rep. 2019 Feb 22;9(1):2619. doi: 10.1038/s41598-019-38935-7.


Quantitation of Purines from Pigeon Guano and Implications for Cryptococcus neoformans Survival During Infection.

Chitty JL, Edwards DJ, Robertson AAB, Butler MS, Duley JA, Cooper MA, Fraser JA.

Mycopathologia. 2019 Apr;184(2):273-281. doi: 10.1007/s11046-018-0315-0. Epub 2019 Feb 1.


Stereotactic radiotherapy for presumed oculomotor nerve schwannoma masquerading as "ophthalmoplegic migraine".

Abo-Shasha R, Bauman GS, Fraser JA.

Can J Ophthalmol. 2018 Oct;53(5):e167-e168. doi: 10.1016/j.jcjo.2017.12.014. Epub 2018 Mar 7. No abstract available.


Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profiles.

Kummari LK, Butler MS, Furlong E, Blundell R, Nouwens A, Silva AB, Kappler U, Fraser JA, Kobe B, Cooper MA, Robertson AAB.

Bioorg Med Chem. 2018 Nov 1;26(20):5408-5419. doi: 10.1016/j.bmc.2018.09.004. Epub 2018 Sep 5.


Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections.

Garcia MD, Chua SMH, Low YS, Lee YT, Agnew-Francis K, Wang JG, Nouwens A, Lonhienne T, Williams CM, Fraser JA, Guddat LW.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):E9649-E9658. doi: 10.1073/pnas.1809422115. Epub 2018 Sep 24.


Chronic Myelomonocytic Leukemia Mimicking Invasive Fungal Rhinosinusitis.

Climans SA, Cecchini MJ, Hsia CC, Bondy LC, Shkrum MJ, Roth KE, Fraser JA.

Can J Neurol Sci. 2018 Sep;45(5):596-598. doi: 10.1017/cjn.2018.320. No abstract available.


Hoarseness of unclear origin may be a sign of cerebrovascular disease and herald impending recurrent brainstem stroke.

Fraser JA.

CMAJ. 2018 Sep 10;190(36):E1088. doi: 10.1503/cmaj.70005. No abstract available.


Comparison of stool collection and storage on Whatman FTA Elute cards versus frozen stool for enteropathogen detection using the TaqMan Array Card PCR assay.

Lalani T, Tisdale MD, Liu J, Mitra I, Philip C, Odundo E, Reyes F, Simons MP, Fraser JA, Hutley E, Connor P, Swierczewski BE, Houpt E, Tribble DR, Riddle MS.

PLoS One. 2018 Aug 30;13(8):e0202178. doi: 10.1371/journal.pone.0202178. eCollection 2018.


Valsalva-triggered pseudotumor cerebri syndrome: Case series and pathogenetic implications.

Chan TLH, Kim DD, Sharma M, Lee DH, Fraser JA.

Neurology. 2018 Aug 21;91(8):e746-e750. doi: 10.1212/WNL.0000000000006048. Epub 2018 Jul 18.


Peripapillary Hyperreflective Ovoid Mass-Like Structures: Is It Optic Disc Drusen or Not?: Response.

Malmqvist L, Bursztyn L, Costello F, Digre K, Fraser JA, Fraser C, Katz B, Lawlor M, Petzold A, Sibony P, Warner J, Wegener M, Wong S, Hamann S.

J Neuroophthalmol. 2018 Dec;38(4):568-570. doi: 10.1097/WNO.0000000000000674. No abstract available.


Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators.

Hommel B, Mukaremera L, Cordero RJB, Coelho C, Desjardins CA, Sturny-Leclère A, Janbon G, Perfect JR, Fraser JA, Casadevall A, Cuomo CA, Dromer F, Nielsen K, Alanio A.

PLoS Pathog. 2018 May 18;14(5):e1006982. doi: 10.1371/journal.ppat.1006982. eCollection 2018 May.


Silver nanoparticles promote the emergence of heterogeneic human neutrophil sub-populations.

Fraser JA, Kemp S, Young L, Ross M, Prach M, Hutchison GR, Malone E.

Sci Rep. 2018 May 14;8(1):7506. doi: 10.1038/s41598-018-25854-2.


Exploring the meaning and practice of self-care among palliative care nurses and doctors: a qualitative study.

Mills J, Wand T, Fraser JA.

BMC Palliat Care. 2018 Apr 18;17(1):63. doi: 10.1186/s12904-018-0318-0.


Effect of Treating Acute Optic Neuritis With Bioequivalent Oral vs Intravenous Corticosteroids: A Randomized Clinical Trial.

Morrow SA, Fraser JA, Day C, Bowman D, Rosehart H, Kremenchutzky M, Nicolle M.

JAMA Neurol. 2018 Jun 1;75(6):690-696. doi: 10.1001/jamaneurol.2018.0024.


Progressive multifocal leukoencephalopathy during ixazomib-based chemotherapy.

Sawicki CP, Climans SA, Hsia CC, Fraser JA.

Curr Oncol. 2018 Feb;25(1):e99-e102. doi: 10.3747/co.25.3674. Epub 2018 Feb 28.


The Long History of the Diverse Roles of Short ORFs: sPEPs in Fungi.

Erpf PE, Fraser JA.

Proteomics. 2018 May;18(10):e1700219. doi: 10.1002/pmic.201700219. Epub 2018 May 4. Review.


The beer and biofuels laboratory: A report on implementing and supporting a large, interdisciplinary, yeast-focused course-based undergraduate research experience.

Pedwell RK, Fraser JA, Wang JTH, Clegg JK, Chartres JD, Rowland SL.

Biochem Mol Biol Educ. 2018 May;46(3):213-222. doi: 10.1002/bmb.21111. Epub 2018 Jan 31.


Examining self-care, self-compassion and compassion for others: a cross-sectional survey of palliative care nurses and doctors.

Mills J, Wand T, Fraser JA.

Int J Palliat Nurs. 2018 Jan 2;24(1):4-11. doi: 10.12968/ijpn.2018.24.1.4.


Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic.

Arras SDM, Ormerod KL, Erpf PE, Espinosa MI, Carpenter AC, Blundell RD, Stowasser SR, Schulz BL, Tanurdzic M, Fraser JA.

Sci Rep. 2017 Dec 20;7(1):17918. doi: 10.1038/s41598-017-18106-2.


Multivariable prediction model for suspected giant cell arteritis: development and validation.

Ing EB, Lahaie Luna G, Toren A, Ing R, Chen JJ, Arora N, Torun N, Jakpor OA, Fraser JA, Tyndel FJ, Sundaram AN, Liu X, Lam CT, Patel V, Weis E, Jordan D, Gilberg S, Pagnoux C, Ten Hove M.

Clin Ophthalmol. 2017 Nov 22;11:2031-2042. doi: 10.2147/OPTH.S151385. eCollection 2017.


Antimicrobial Octapeptin C4 Analogues Active against Cryptococcus Species.

Chitty JL, Butler MS, Suboh A, Edwards DJ, Cooper MA, Fraser JA, Robertson AAB.

Antimicrob Agents Chemother. 2018 Jan 25;62(2). pii: e00986-17. doi: 10.1128/AAC.00986-17. Print 2018 Feb.


The Optic Disc Drusen Studies Consortium Recommendations for Diagnosis of Optic Disc Drusen Using Optical Coherence Tomography.

Malmqvist L, Bursztyn L, Costello F, Digre K, Fraser JA, Fraser C, Katz B, Lawlor M, Petzold A, Sibony P, Warner J, Wegener M, Wong S, Hamann S.

J Neuroophthalmol. 2018 Sep;38(3):299-307. doi: 10.1097/WNO.0000000000000585.


Preferential activation of HIF-2α adaptive signalling in neuronal-like cells in response to acute hypoxia.

Martín-Aragón Baudel MAS, Rae MT, Darlison MG, Poole AV, Fraser JA.

PLoS One. 2017 Oct 2;12(10):e0185664. doi: 10.1371/journal.pone.0185664. eCollection 2017.


Pro-arrhythmic atrial phenotypes in incrementally paced murine Pgc1β-/- hearts: effects of age.

Valli H, Ahmad S, Fraser JA, Jeevaratnam K, Huang CL.

Exp Physiol. 2017 Dec 1;102(12):1619-1634. doi: 10.1113/EP086589. Epub 2017 Oct 29.


Importance of Resolving Fungal Nomenclature: the Case of Multiple Pathogenic Species in the Cryptococcus Genus.

Hagen F, Lumbsch HT, Arsic Arsenijevic V, Badali H, Bertout S, Billmyre RB, Bragulat MR, Cabañes FJ, Carbia M, Chakrabarti A, Chaturvedi S, Chaturvedi V, Chen M, Chowdhary A, Colom MF, Cornely OA, Crous PW, Cuétara MS, Diaz MR, Espinel-Ingroff A, Fakhim H, Falk R, Fang W, Herkert PF, Ferrer Rodríguez C, Fraser JA, Gené J, Guarro J, Idnurm A, Illnait-Zaragozi MT, Khan Z, Khayhan K, Kolecka A, Kurtzman CP, Lagrou K, Liao W, Linares C, Meis JF, Nielsen K, Nyazika TK, Pan W, Pekmezovic M, Polacheck I, Posteraro B, de Queiroz Telles F Filho, Romeo O, Sánchez M, Sampaio A, Sanguinetti M, Sriburee P, Sugita T, Taj-Aldeen SJ, Takashima M, Taylor JW, Theelen B, Tomazin R, Verweij PE, Wahyuningsih R, Wang P, Boekhout T.

mSphere. 2017 Aug 30;2(4). pii: e00238-17. doi: 10.1128/mSphere.00238-17. eCollection 2017 Jul-Aug.


A fluorogenic C. neoformans reporter strain with a robust expression of m-cherry expressed from a safe haven site in the genome.

Upadhya R, Lam WC, Maybruck BT, Donlin MJ, Chang AL, Kayode S, Ormerod KL, Fraser JA, Doering TL, Lodge JK.

Fungal Genet Biol. 2017 Nov;108:13-25. doi: 10.1016/j.fgb.2017.08.008. Epub 2017 Sep 12.


Prevention and recognition of abusive head trauma: training for healthcare professionals in Vietnam.

Fraser JA, Flemington T, Doan TND, Hoang MTV, Doan TLB, Ha MT.

Acta Paediatr. 2017 Oct;106(10):1608-1616. doi: 10.1111/apa.13977. Epub 2017 Aug 11.


Dento-corneal aberrant regeneration as evidence of V2 innervation of the inferior human cornea.

Bery A, Fraser JA.

Neurology. 2017 Jul 18;89(3):302-303. doi: 10.1212/WNL.0000000000004122. Epub 2017 Jun 14. No abstract available.


Purine Acquisition and Synthesis by Human Fungal Pathogens.

Chitty JL, Fraser JA.

Microorganisms. 2017 Jun 8;5(2). pii: E33. doi: 10.3390/microorganisms5020033. Review.


Cryptococcus neoformans ADS lyase is an enzyme essential for virulence whose crystal structure reveals features exploitable in antifungal drug design.

Chitty JL, Blake KL, Blundell RD, Koh YQAE, Thompson M, Robertson AAB, Butler MS, Cooper MA, Kappler U, Williams SJ, Kobe B, Fraser JA.

J Biol Chem. 2017 Jul 14;292(28):11829-11839. doi: 10.1074/jbc.M117.787994. Epub 2017 May 30.


Palliative care professionals' care and compassion for self and others: a narrative review.

Mills J, Wand T, Fraser JA.

Int J Palliat Nurs. 2017 May 2;23(5):219-229. doi: 10.12968/ijpn.2017.23.5.219. Review.


RE: Traber et al.: Enhanced depth imaging optical coherence tomography of optic nerve head drusen: a comparison of cases with and without visual field loss (Ophthalmology. 2017;124:66-73).

Malmqvist L, Fraser C, Fraser JA, Lawlor M, Hamann S.

Ophthalmology. 2017 Jun;124(6):e55-e56. doi: 10.1016/j.ophtha.2017.01.007. No abstract available.


Sirtuins in the phylum Basidiomycota: A role in virulence in Cryptococcus neoformans.

Arras SDM, Chitty JL, Wizrah MSI, Erpf PE, Schulz BL, Tanurdzic M, Fraser JA.

Sci Rep. 2017 Apr 21;7:46567. doi: 10.1038/srep46567.


Calcium-dependent Nedd4-2 upregulation mediates degradation of the cardiac sodium channel Nav1.5: implications for heart failure.

Luo L, Ning F, Du Y, Song B, Yang D, Salvage SC, Wang Y, Fraser JA, Zhang S, Ma A, Wang T.

Acta Physiol (Oxf). 2017 Sep;221(1):44-58. doi: 10.1111/apha.12872. Epub 2017 Apr 6.


Selective Extraocular Muscle Atrophy Secondary to Chronic Oculomotor Denervation.

Szigiato AA, Lee DH, Fraser JA.

JAMA Ophthalmol. 2017 Feb 9;135(2):e164664. doi: 10.1001/jamaophthalmol.2016.4664. Epub 2017 Feb 9. No abstract available.


The 2.0 Å X-ray structure for yeast acetohydroxyacid synthase provides new insights into its cofactor and quaternary structure requirements.

Lonhienne T, Garcia MD, Fraser JA, Williams CM, Guddat LW.

PLoS One. 2017 Feb 8;12(2):e0171443. doi: 10.1371/journal.pone.0171443. eCollection 2017.


Optic Neuritis in Guillain-Barre Syndrome.

Dayal AM, Kimpinski K, Fraser JA.

Can J Neurol Sci. 2017 Jul;44(4):449-451. doi: 10.1017/cjn.2016.452. Epub 2017 Feb 1. No abstract available.


Self-Care in Palliative Care Nursing and Medical Professionals: A Cross-Sectional Survey.

Mills J, Wand T, Fraser JA.

J Palliat Med. 2017 Jun;20(6):625-630. doi: 10.1089/jpm.2016.0470. Epub 2017 Jan 16.


GMP Synthase Is Required for Virulence Factor Production and Infection by Cryptococcus neoformans.

Chitty JL, Tatzenko TL, Williams SJ, Koh YQ, Corfield EC, Butler MS, Robertson AA, Cooper MA, Kappler U, Kobe B, Fraser JA.

J Biol Chem. 2017 Feb 17;292(7):3049-3059. doi: 10.1074/jbc.M116.767533. Epub 2017 Jan 6.


Quantitative evaluation of vision-related and health-related quality of life after endoscopic transsphenoidal surgery for pituitary adenoma.

Wolf A, Coros A, Bierer J, Goncalves S, Cooper P, Van Uum S, Lee DH, Proulx A, Nicolle D, Fraser JA, Rotenberg BW, Duggal N.

J Neurosurg. 2017 Aug;127(2):409-416. doi: 10.3171/2016.7.JNS16200. Epub 2016 Oct 7.


Teaching Video NeuroImages: Video-ophthalmoscopy: Nystagmus from the inside.

Fraser JA.

Neurology. 2016 Oct 25;87(17):e210. No abstract available.


Abducens neuromyotonia: a delayed neuro-ophthalmic complication of cranial radiation.

Khimdas S, Fraser JA.

Can J Ophthalmol. 2016 Oct;51(5):e157-e158. doi: 10.1016/j.jcjo.2016.05.020. Epub 2016 Aug 1. No abstract available.


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