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Items: 1 to 50 of 101

1.

Assessment of rosacea symptom severity by genome-wide association study and expression analysis highlights immuno-inflammatory and skin pigmentation genes.

Aponte JL, Chiano MN, Yerges-Armstrong LM, Hinds DA, Tian C, Gupta A, Guo C, Fraser DJ, Freudenberg JM, Rajpal DK, Ehm MG, Waterworth DM.

Hum Mol Genet. 2018 May 16. doi: 10.1093/hmg/ddy184. [Epub ahead of print]

PMID:
29771307
2.

Evaluating a 5-year metal contamination remediation and the biomonitoring potential of a freshwater gastropod along the Xiangjiang River, China.

Li D, Pi J, Zhang T, Tan X, Fraser DJ.

Environ Sci Pollut Res Int. 2018 May 16. doi: 10.1007/s11356-018-2263-0. [Epub ahead of print]

PMID:
29770938
3.

Genetic diversity of small populations: Not always "doom and gloom"?

Fraser DJ.

Mol Ecol. 2017 Dec;26(23):6499-6501. doi: 10.1111/mec.14371.

PMID:
29243868
4.

A critical assessment of estimating census population size from genetic population size (or vice versa) in three fishes.

Yates MC, Bernos TA, Fraser DJ.

Evol Appl. 2017 Jul 4;10(9):935-945. doi: 10.1111/eva.12496. eCollection 2017 Oct.

5.

The evolutionary consequences of habitat fragmentation: Body morphology and coloration differentiation among brook trout populations of varying size.

Zastavniouk C, Weir LK, Fraser DJ.

Ecol Evol. 2017 Jul 27;7(17):6850-6862. doi: 10.1002/ece3.3229. eCollection 2017 Sep.

6.

MicroRNAs as biomarkers in chronic kidney disease.

Wonnacott A, Bowen T, Fraser DJ.

Curr Opin Nephrol Hypertens. 2017 Nov;26(6):460-466. doi: 10.1097/MNH.0000000000000356. Review.

PMID:
28806192
7.

Characterisation of the HLA-DRB1*07:01 biomarker for lapatinib-induced liver toxicity during treatment of early-stage breast cancer patients with lapatinib in combination with trastuzumab and/or taxanes.

Spraggs CF, Parham LR, Briley LP, Warren L, Williams LS, Fraser DJ, Jiang Z, Aziz Z, Ahmed S, Demetriou G, Mehta A, Jackson N, Byrne J, Andersson M, Toi M, Harris L, Gralow J, Zujewski JA, Crescenzo R, Armour A, Perez E, Piccart M.

Pharmacogenomics J. 2018 May 22;18(3):480-486. doi: 10.1038/tpj.2017.39. Epub 2017 Aug 8.

PMID:
28786423
8.

Current practice in total-body irradiation: results of a Canada-wide survey.

Studinski RCN, Fraser DJ, Samant RS, MacPherson MS.

Curr Oncol. 2017 Jun;24(3):181-186. doi: 10.3747/co.24.3484. Epub 2017 Jun 27.

9.

Telomere length profiles in primary human peritoneal mesothelial cells are consistent with senescence.

Lopez-Anton M, Rudolf A, Baird DM, Roger L, Jones RE, Witowski J, Fraser DJ, Bowen T.

Mech Ageing Dev. 2017 Jun;164:37-40. doi: 10.1016/j.mad.2017.03.010. Epub 2017 Apr 1.

PMID:
28373051
10.

Machine-learning algorithms define pathogen-specific local immune fingerprints in peritoneal dialysis patients with bacterial infections.

Zhang J, Friberg IM, Kift-Morgan A, Parekh G, Morgan MP, Liuzzi AR, Lin CY, Donovan KL, Colmont CS, Morgan PH, Davis P, Weeks I, Fraser DJ, Topley N, Eberl M.

Kidney Int. 2017 Jul;92(1):179-191. doi: 10.1016/j.kint.2017.01.017. Epub 2017 Mar 17.

11.

Peritoneal macrophage heterogeneity is associated with different peritoneal dialysis outcomes.

Liao CT, Andrews R, Wallace LE, Khan MW, Kift-Morgan A, Topley N, Fraser DJ, Taylor PR.

Kidney Int. 2017 May;91(5):1088-1103. doi: 10.1016/j.kint.2016.10.030. Epub 2017 Jan 5.

12.

Limited variability in upper thermal tolerance among pure and hybrid populations of a cold-water fish.

Wells ZR, McDonnell LH, Chapman LJ, Fraser DJ.

Conserv Physiol. 2016 Dec 15;4(1):cow063. eCollection 2016.

13.

Striking Phenotypic Variation yet Low Genetic Differentiation in Sympatric Lake Trout (Salvelinus namaycush).

Marin K, Coon A, Carson R, Debes PV, Fraser DJ.

PLoS One. 2016 Sep 28;11(9):e0162325. doi: 10.1371/journal.pone.0162325. eCollection 2016.

14.

Unconventional Human T Cells Accumulate at the Site of Infection in Response to Microbial Ligands and Induce Local Tissue Remodeling.

Liuzzi AR, Kift-Morgan A, Lopez-Anton M, Friberg IM, Zhang J, Brook AC, Roberts GW, Donovan KL, Colmont CS, Toleman MA, Bowen T, Johnson DW, Topley N, Moser B, Fraser DJ, Eberl M.

J Immunol. 2016 Sep 15;197(6):2195-207. doi: 10.4049/jimmunol.1600990. Epub 2016 Aug 15.

15.

Spatiotemporal relationship between adult census size and genetic population size across a wide population size gradient.

Bernos TA, Fraser DJ.

Mol Ecol. 2016 Sep;25(18):4472-87. doi: 10.1111/mec.13790. Epub 2016 Sep 6.

PMID:
27483203
16.

IL-10 differentially controls the infiltration of inflammatory macrophages and antigen-presenting cells during inflammation.

Liao CT, Rosas M, Davies LC, Giles PJ, Tyrrell VJ, O'Donnell VB, Topley N, Humphreys IR, Fraser DJ, Jones SA, Taylor PR.

Eur J Immunol. 2016 Sep;46(9):2222-32. doi: 10.1002/eji.201646528. Epub 2016 Jul 28.

17.

Are heritability and selection related to population size in nature? Meta-analysis and conservation implications.

Wood JL, Yates MC, Fraser DJ.

Evol Appl. 2016 Apr 3;9(5):640-57. doi: 10.1111/eva.12375. eCollection 2016 Jun. Review.

18.

MicroRNAs in Diabetic Nephropathy: From Biomarkers to Therapy.

Simpson K, Wonnacott A, Fraser DJ, Bowen T.

Curr Diab Rep. 2016 Mar;16(3):35. doi: 10.1007/s11892-016-0724-8. Review.

19.

Addressing Peritoneal Dialysis: In Vitro PD Models, In Vivo Rodent PD Model, Clinical Biobanks, and Underutilization of PD.

Beelen RH, Fraser DJ, Rutherford P, Witowski J.

Biomed Res Int. 2016;2016:4964316. doi: 10.1155/2016/4964316. Epub 2016 Jan 3. No abstract available.

20.

MicroRNA-21 (miR-21) expression in hypothermic machine perfusate may be predictive of early outcomes in kidney transplantation.

Khalid U, Ablorsu E, Szabo L, Jenkins RH, Bowen T, Chavez R, Fraser DJ.

Clin Transplant. 2016 Feb;30(2):99-104. doi: 10.1111/ctr.12679. Epub 2016 Jan 5.

PMID:
26660281
21.

A Localized Ischemic Preconditioning Regimen Increases Tumor Necrosis Factor α Expression in a Rat Model of Kidney Ischemia-Reperfusion Injury.

Khalid U, Jenkins RH, Pino-Chavez G, Bowen T, Fraser DJ, Chavez R.

Exp Clin Transplant. 2015 Dec;13(6):535-42.

22.

HLA-B*57:01 Confers Susceptibility to Pazopanib-Associated Liver Injury in Patients with Cancer.

Xu CF, Johnson T, Wang X, Carpenter C, Graves AP, Warren L, Xue Z, King KS, Fraser DJ, Stinnett S, Briley LP, Mitrica I, Spraggs CF, Nelson MR, Tada H, du Bois A, Powles T, Kaplowitz N, Pandite LN.

Clin Cancer Res. 2016 Mar 15;22(6):1371-7. doi: 10.1158/1078-0432.CCR-15-2044. Epub 2015 Nov 6.

23.

Peritoneal Dialysis Fluid and Some of Its Components Potentiate Fibrocyte Differentiation.

Herlihy SE, Starke HE, Lopez-Anton M, Cox N, Keyhanian K, Fraser DJ, Gomer RH.

Perit Dial Int. 2016 Jul-Aug;36(4):367-73. doi: 10.3747/pdi.2014.00284. Epub 2015 Oct 22.

24.

Stabilization of Urinary MicroRNAs by Association with Exosomes and Argonaute 2 Protein.

Beltrami C, Clayton A, Newbury LJ, Corish P, Jenkins RH, Phillips AO, Fraser DJ, Bowen T.

Noncoding RNA. 2015 Sep 14;1(2):151-166. doi: 10.3390/ncrna1020151.

25.
26.

Population size is weakly related to quantitative genetic variation and trait differentiation in a stream fish.

Wood JL, Tezel D, Joyal D, Fraser DJ.

Evolution. 2015 Sep;69(9):2303-18. doi: 10.1111/evo.12733. Epub 2015 Aug 20.

PMID:
26207947
27.

Does human-induced hybridization have long-term genetic effects? Empirical testing with domesticated, wild and hybridized fish populations.

Harbicht A, Wilson CC, Fraser DJ.

Evol Appl. 2014 Dec;7(10):1180-91. doi: 10.1111/eva.12199. Epub 2014 Aug 27.

28.

Does source population size affect performance in new environments?

Yates MC, Fraser DJ.

Evol Appl. 2014 Sep;7(8):871-82. doi: 10.1111/eva.12181. Epub 2014 Jul 9. Review.

29.

Relationship of habitat variability to population size in a stream fish.

Wood JL, Belmar-Lucero S, Hutchings IJ, Fraser DJ.

Ecol Appl. 2014 Jul;24(5):1085-100.

PMID:
25154098
30.

Acute kidney injury: a paradigm for miRNA regulation of the cell cycle.

Khalid U, Bowen T, Fraser DJ, Jenkins RH.

Biochem Soc Trans. 2014 Aug;42(4):1219-23. doi: 10.1042/BST20140093. Review.

PMID:
25110028
31.

Population size, habitat fragmentation, and the nature of adaptive variation in a stream fish.

Fraser DJ, Debes PV, Bernatchez L, Hutchings JA.

Proc Biol Sci. 2014 Sep 7;281(1790). pii: 20140370. doi: 10.1098/rspb.2014.0370.

32.

Interleukin-6 in renal disease and therapy.

Jones SA, Fraser DJ, Fielding CA, Jones GW.

Nephrol Dial Transplant. 2015 Apr;30(4):564-74. doi: 10.1093/ndt/gfu233. Epub 2014 Jul 10. Review.

PMID:
25011387
33.

Evolutionary hypotheses for a constraint to life-history resilience in depleted Salmo salar populations.

Fraser DJ.

J Fish Biol. 2014 Jul;85(1):119-31. doi: 10.1111/jfb.12379. Epub 2014 Apr 28.

PMID:
24766616
34.

The transcription factor Gata6 links tissue macrophage phenotype and proliferative renewal.

Rosas M, Davies LC, Giles PJ, Liao CT, Kharfan B, Stone TC, O'Donnell VB, Fraser DJ, Jones SA, Taylor PR.

Science. 2014 May 9;344(6184):645-648. doi: 10.1126/science.1251414. Epub 2014 Apr 24.

35.

miR-192 induces G2/M growth arrest in aristolochic acid nephropathy.

Jenkins RH, Davies LC, Taylor PR, Akiyama H, Cumbes B, Beltrami C, Carrington CP, Phillips AO, Bowen T, Fraser DJ.

Am J Pathol. 2014 Apr;184(4):996-1009. doi: 10.1016/j.ajpath.2013.12.028. Epub 2014 Feb 5.

PMID:
24508230
36.

The between-population genetic architecture of growth, maturation, and plasticity in Atlantic salmon.

Debes PV, Fraser DJ, Yates M, Hutchings JA.

Genetics. 2014 Apr;196(4):1277-91. doi: 10.1534/genetics.114.161729. Epub 2014 Jan 28.

37.

Multidisciplinary population monitoring when demographic data are sparse: a case study of remote trout populations.

Fraser DJ, Calvert AM, Bernatchez L, Coon A.

Ecol Evol. 2013 Dec;3(15):4954-69. doi: 10.1002/ece3.871. Epub 2013 Nov 8.

38.
39.

Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation.

Davies LC, Rosas M, Jenkins SJ, Liao CT, Scurr MJ, Brombacher F, Fraser DJ, Allen JE, Jones SA, Taylor PR.

Nat Commun. 2013;4:1886. doi: 10.1038/ncomms2877.

40.

Multigenerational hybridisation and its consequences for maternal effects in Atlantic salmon.

Debes PV, Fraser DJ, McBride MC, Hutchings JA.

Heredity (Edinb). 2013 Sep;111(3):238-47. doi: 10.1038/hdy.2013.43. Epub 2013 May 8.

41.

Kinship analysis of brook trout Salvelinus fontinalis during their breeding migration.

Meli A, Fraser DJ.

J Fish Biol. 2013 May;82(5):1514-22. doi: 10.1111/jfb.12082.

PMID:
23639151
42.

Effective/census population size ratio estimation: a compendium and appraisal.

Palstra FP, Fraser DJ.

Ecol Evol. 2012 Sep;2(9):2357-65. doi: 10.1002/ece3.329. Epub 2012 Jul 25.

43.

MicroRNAs, transforming growth factor beta-1, and tissue fibrosis.

Bowen T, Jenkins RH, Fraser DJ.

J Pathol. 2013 Jan;229(2):274-85. doi: 10.1002/path.4119. Epub 2012 Nov 29. Review.

PMID:
23042530
44.

Concurrent habitat and life history influences on effective/census population size ratios in stream-dwelling trout.

Belmar-Lucero S, Wood JL, Scott S, Harbicht AB, Hutchings JA, Fraser DJ.

Ecol Evol. 2012 Mar;2(3):562-73. doi: 10.1002/ece3.196.

45.

Analysis of urinary microRNAs in chronic kidney disease.

Beltrami C, Clayton A, Phillips AO, Fraser DJ, Bowen T.

Biochem Soc Trans. 2012 Aug;40(4):875-9. doi: 10.1042/BST20120090. Review.

PMID:
22817751
46.

Pleiotropy of microRNA-192 in the kidney.

Jenkins RH, Martin J, Phillips AO, Bowen T, Fraser DJ.

Biochem Soc Trans. 2012 Aug;40(4):762-7. doi: 10.1042/BST20120085. Review.

PMID:
22817730
47.

Differences in transcription levels among wild, domesticated, and hybrid Atlantic salmon (Salmo salar) from two environments.

Debes PV, Normandeau E, Fraser DJ, Bernatchez L, Hutchings JA.

Mol Ecol. 2012 Jun;21(11):2574-87. doi: 10.1111/j.1365-294X.2012.05567.x. Epub 2012 Apr 23.

PMID:
22519555
48.

Deep resequencing unveils genetic architecture of ADIPOQ and identifies a novel low-frequency variant strongly associated with adiponectin variation.

Warren LL, Li L, Nelson MR, Ehm MG, Shen J, Fraser DJ, Aponte JL, Nangle KL, Slater AJ, Woollard PM, Hall MD, Topp SD, Yuan X, Cardon LR, Chissoe SL, Mooser V, Morris AD, Palmer CN, Perry JR, Frayling TM, Whittaker JC, Waterworth DM.

Diabetes. 2012 May;61(5):1297-301. doi: 10.2337/db11-0985. Epub 2012 Mar 8.

49.

Transforming growth factor β1 represses proximal tubular cell microRNA-192 expression through decreased hepatocyte nuclear factor DNA binding.

Jenkins RH, Martin J, Phillips AO, Bowen T, Fraser DJ.

Biochem J. 2012 Apr 15;443(2):407-16. doi: 10.1042/BJ20111861.

PMID:
22264233
50.

Post-transcriptional regulation of Transforming Growth Factor Beta-1 by microRNA-744.

Martin J, Jenkins RH, Bennagi R, Krupa A, Phillips AO, Bowen T, Fraser DJ.

PLoS One. 2011;6(10):e25044. doi: 10.1371/journal.pone.0025044. Epub 2011 Oct 4.

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