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Items: 42


Nucleome Dynamics during Retinal Development.

Norrie JL, Lupo MS, Xu B, Al Diri I, Valentine M, Putnam D, Griffiths L, Zhang J, Johnson D, Easton J, Shao Y, Honnell V, Frase S, Miller S, Stewart V, Zhou X, Chen X, Dyer MA.

Neuron. 2019 Aug 21. pii: S0896-6273(19)30686-5. doi: 10.1016/j.neuron.2019.08.002. [Epub ahead of print]


RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity.

Orozco SL, Daniels BP, Yatim N, Messmer MN, Quarato G, Chen-Harris H, Cullen SP, Snyder AG, Ralli-Jain P, Frase S, Tait SWG, Green DR, Albert ML, Oberst A.

Cell Rep. 2019 Aug 27;28(9):2275-2287.e5. doi: 10.1016/j.celrep.2019.07.077.


Corrigendum to "Metabolic switching in pluripotent stem cells reorganizes energy metabolism and subcellular organelles" [379 (2019) 55-64].

O'Reilly C, Cho JH, Qi Q, Peters JL, Fukuda Y, Frase S, Peng J, Schuetz JD, Cheng Y, Yoon SO, Han MJ.

Exp Cell Res. 2019 Aug 1;381(1):163. doi: 10.1016/j.yexcr.2019.05.002. Epub 2019 May 9. No abstract available.


Metabolic switching in pluripotent stem cells reorganizes energy metabolism and subcellular organelles.

O'Reilly C, Cho JH, Qi Q, Peters JL, Fukuda Y, Frase S, Peng J, Schuetz JD, Cheng Y, Yoon SO, Han MJ.

Exp Cell Res. 2019 Jun 1;379(1):55-64. doi: 10.1016/j.yexcr.2019.03.028. Epub 2019 Mar 25. Erratum in: Exp Cell Res. 2019 Aug 1;381(1):163.


SIL1, the endoplasmic-reticulum-localized BiP co-chaperone, plays a crucial role in maintaining skeletal muscle proteostasis and physiology.

Ichhaporia VP, Kim J, Kavdia K, Vogel P, Horner L, Frase S, Hendershot LM.

Dis Model Mech. 2018 May 10;11(5). pii: dmm033043. doi: 10.1242/dmm.033043.


Retinal Cell Type DNA Methylation and Histone Modifications Predict Reprogramming Efficiency and Retinogenesis in 3D Organoid Cultures.

Wang L, Hiler D, Xu B, AlDiri I, Chen X, Zhou X, Griffiths L, Valentine M, Shirinifard A, Sablauer A, Thiagarajan S, Barabas ME, Zhang J, Johnson D, Frase S, Dyer MA.

Cell Rep. 2018 Mar 6;22(10):2601-2614. doi: 10.1016/j.celrep.2018.01.075.


Antidepressants Rescue Stress-Induced Disruption of Synaptic Plasticity via Serotonin Transporter-Independent Inhibition of L-Type Calcium Channels.

Normann C, Frase S, Haug V, von Wolff G, Clark K, Münzer P, Dorner A, Scholliers J, Horn M, Vo Van T, Seifert G, Serchov T, Biber K, Nissen C, Klugbauer N, Bischofberger J.

Biol Psychiatry. 2018 Jul 1;84(1):55-64. doi: 10.1016/j.biopsych.2017.10.008. Epub 2017 Oct 19.


The autophagy-inducing kinases, ULK1 and ULK2, regulate axon guidance in the developing mouse forebrain via a noncanonical pathway.

Wang B, Iyengar R, Li-Harms X, Joo JH, Wright C, Lavado A, Horner L, Yang M, Guan JL, Frase S, Green DR, Cao X, Kundu M.

Autophagy. 2018;14(5):796-811. doi: 10.1080/15548627.2017.1386820. Epub 2017 Dec 24.


The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis.

Aldiri I, Xu B, Wang L, Chen X, Hiler D, Griffiths L, Valentine M, Shirinifard A, Thiagarajan S, Sablauer A, Barabas ME, Zhang J, Johnson D, Frase S, Zhou X, Easton J, Zhang J, Mardis ER, Wilson RK, Downing JR, Dyer MA; St. Jude Children’s Research Hospital—Washington University Pediatric Cancer Genome Project.

Neuron. 2017 May 3;94(3):550-568.e10. doi: 10.1016/j.neuron.2017.04.022.


Excess coenzyme A reduces skeletal muscle performance and strength in mice overexpressing human PANK2.

Corbin DR, Rehg JE, Shepherd DL, Stoilov P, Percifield RJ, Horner L, Frase S, Zhang YM, Rock CO, Hollander JM, Jackowski S, Leonardi R.

Mol Genet Metab. 2017 Apr;120(4):350-362. doi: 10.1016/j.ymgme.2017.02.001. Epub 2017 Feb 3.


IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.

Man SM, Karki R, Sasai M, Place DE, Kesavardhana S, Temirov J, Frase S, Zhu Q, Malireddi RKS, Kuriakose T, Peters JL, Neale G, Brown SA, Yamamoto M, Kanneganti TD.

Cell. 2016 Oct 6;167(2):382-396.e17. doi: 10.1016/j.cell.2016.09.012. Epub 2016 Sep 29.


The severity of hereditary porphyria is modulated by the porphyrin exporter and Lan antigen ABCB6.

Fukuda Y, Cheong PL, Lynch J, Brighton C, Frase S, Kargas V, Rampersaud E, Wang Y, Sankaran VG, Yu B, Ney PA, Weiss MJ, Vogel P, Bond PJ, Ford RC, Trent RJ, Schuetz JD.

Nat Commun. 2016 Aug 10;7:12353. doi: 10.1038/ncomms12353.


Msh2 deficiency leads to dysmyelination of the corpus callosum, impaired locomotion, and altered sensory function in mice.

Diouf B, Devaraju P, Janke LJ, Fan Y, Frase S, Eddins D, Peters JL, Kim J, Pei D, Cheng C, Zakharenko SS, Evans WE.

Sci Rep. 2016 Aug 1;6:30757. doi: 10.1038/srep30757.


Alix-mediated assembly of the actomyosin-tight junction polarity complex preserves epithelial polarity and epithelial barrier.

Campos Y, Qiu X, Gomero E, Wakefield R, Horner L, Brutkowski W, Han YG, Solecki D, Frase S, Bongiovanni A, d'Azzo A.

Nat Commun. 2016 Jun 23;7:11876. doi: 10.1038/ncomms11876.


DOCK2 confers immunity and intestinal colonization resistance to Citrobacter rodentium infection.

Liu Z, Man SM, Zhu Q, Vogel P, Frase S, Fukui Y, Kanneganti TD.

Sci Rep. 2016 Jun 13;6:27814. doi: 10.1038/srep27814.


Sequential Engagement of Distinct MLKL Phosphatidylinositol-Binding Sites Executes Necroptosis.

Quarato G, Guy CS, Grace CR, Llambi F, Nourse A, Rodriguez DA, Wakefield R, Frase S, Moldoveanu T, Green DR.

Mol Cell. 2016 Feb 18;61(4):589-601. doi: 10.1016/j.molcel.2016.01.011. Epub 2016 Feb 4.


Apoptosis-Inducing-Factor-Dependent Mitochondrial Function Is Required for T Cell but Not B Cell Function.

Milasta S, Dillon CP, Sturm OE, Verbist KC, Brewer TL, Quarato G, Brown SA, Frase S, Janke LJ, Perry SS, Thomas PG, Green DR.

Immunity. 2016 Jan 19;44(1):88-102. doi: 10.1016/j.immuni.2015.12.002. Epub 2016 Jan 12.


Apoptosome activation, an important molecular instigator in 6-mercaptopurine induced Leydig cell death.

Morgan JA, Lynch J, Panetta JC, Wang Y, Frase S, Bao J, Zheng J, Opferman JT, Janke L, Green DM, Chemaitilly W, Schuetz JD.

Sci Rep. 2015 Nov 18;5:16488. doi: 10.1038/srep16488.


Maternal bile acid transporter deficiency promotes neonatal demise.

Zhang Y, Li F, Wang Y, Pitre A, Fang ZZ, Frank MW, Calabrese C, Krausz KW, Neale G, Frase S, Vogel P, Rock CO, Gonzalez FJ, Schuetz JD.

Nat Commun. 2015 Sep 29;6:8186. doi: 10.1038/ncomms9186.


The ABCC4 membrane transporter modulates platelet aggregation.

Cheepala SB, Pitre A, Fukuda Y, Takenaka K, Zhang Y, Wang Y, Frase S, Pestina T, Gartner TK, Jackson C, Schuetz JD.

Blood. 2015 Nov 12;126(20):2307-19. doi: 10.1182/blood-2014-08-595942. Epub 2015 Sep 24.


Outer Hair Cell Lateral Wall Structure Constrains the Mobility of Plasma Membrane Proteins.

Yamashita T, Hakizimana P, Wu S, Hassan A, Jacob S, Temirov J, Fang J, Mellado-Lagarde M, Gursky R, Horner L, Leibiger B, Leijon S, Centonze VE, Berggren PO, Frase S, Auer M, Brownell WE, Fridberger A, Zuo J.

PLoS Genet. 2015 Sep 9;11(9):e1005500. doi: 10.1371/journal.pgen.1005500. eCollection 2015 Sep.


Quantification of Retinogenesis in 3D Cultures Reveals Epigenetic Memory and Higher Efficiency in iPSCs Derived from Rod Photoreceptors.

Hiler D, Chen X, Hazen J, Kupriyanov S, Carroll PA, Qu C, Xu B, Johnson D, Griffiths L, Frase S, Rodriguez AR, Martin G, Zhang J, Jeon J, Fan Y, Finkelstein D, Eisenman RN, Baldwin K, Dyer MA.

Cell Stem Cell. 2015 Jul 2;17(1):101-15. doi: 10.1016/j.stem.2015.05.015.


Widespread mitochondrial depletion via mitophagy does not compromise necroptosis.

Tait SW, Oberst A, Quarato G, Milasta S, Haller M, Wang R, Karvela M, Ichim G, Yatim N, Albert ML, Kidd G, Wakefield R, Frase S, Krautwald S, Linkermann A, Green DR.

Cell Rep. 2013 Nov 27;5(4):878-85. doi: 10.1016/j.celrep.2013.10.034. Epub 2013 Nov 21.


Deletion of MCL-1 causes lethal cardiac failure and mitochondrial dysfunction.

Wang X, Bathina M, Lynch J, Koss B, Calabrese C, Frase S, Schuetz JD, Rehg JE, Opferman JT.

Genes Dev. 2013 Jun 15;27(12):1351-64. doi: 10.1101/gad.215855.113.


Susceptibility of avian influenza viruses of the N6 subtype to the neuraminidase inhibitor oseltamivir.

Stoner TD, Krauss S, Turner JC, Seiler P, Negovetich NJ, Stallknecht DE, Frase S, Govorkova EA, Webster RG.

Antiviral Res. 2012 Mar;93(3):322-9. doi: 10.1016/j.antiviral.2011.12.013. Epub 2012 Jan 10.


Retinoblastoma (Rb) regulates laminar dendritic arbor reorganization in retinal horizontal neurons.

Martins RA, Davis D, Kerekes R, Zhang J, Bayazitov IT, Hiler D, Karakaya M, Frase S, Gleason S, Zakharenko SS, Johnson DA, Dyer MA.

Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21111-6. doi: 10.1073/pnas.1108141108. Epub 2011 Dec 12.


Real-time ophthalmoscopic findings of superselective intraophthalmic artery chemotherapy in a nonhuman primate model.

Wilson MW, Jackson JS, Phillips BX, Buchanan J, Frase S, Wang F, Steinle JJ, Stewart CF, Mandrell TD, Haik BG, Williams JS.

Arch Ophthalmol. 2011 Nov;129(11):1458-65. doi: 10.1001/archophthalmol.2011.330.


Preclinical models for neuroblastoma: establishing a baseline for treatment.

Teitz T, Stanke JJ, Federico S, Bradley CL, Brennan R, Zhang J, Johnson MD, Sedlacik J, Inoue M, Zhang ZM, Frase S, Rehg JE, Hillenbrand CM, Finkelstein D, Calabrese C, Dyer MA, Lahti JM.

PLoS One. 2011 Apr 29;6(4):e19133. doi: 10.1371/journal.pone.0019133.


Cells previously identified as retinal stem cells are pigmented ciliary epithelial cells.

Cicero SA, Johnson D, Reyntjens S, Frase S, Connell S, Chow LM, Baker SJ, Sorrentino BP, Dyer MA.

Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6685-90. doi: 10.1073/pnas.0901596106. Epub 2009 Apr 3.


Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity.

Johnson NC, Dillard ME, Baluk P, McDonald DM, Harvey NL, Frase SL, Oliver G.

Genes Dev. 2008 Dec 1;22(23):3282-91. doi: 10.1101/gad.1727208.


Differentiated horizontal interneurons clonally expand to form metastatic retinoblastoma in mice.

Ajioka I, Martins RA, Bayazitov IT, Donovan S, Johnson DA, Frase S, Cicero SA, Boyd K, Zakharenko SS, Dyer MA.

Cell. 2007 Oct 19;131(2):378-90.


Neuronal differentiation and synaptogenesis in retinoblastoma.

Johnson DA, Zhang J, Frase S, Wilson M, Rodriguez-Galindo C, Dyer MA.

Cancer Res. 2007 Mar 15;67(6):2701-11.


Overexpression of apolipoprotein A-IV enhances lipid secretion in IPEC-1 cells by increasing chylomicron size.

Lu S, Yao Y, Cheng X, Mitchell S, Leng S, Meng S, Gallagher JW, Shelness GS, Morris GS, Mahan J, Frase S, Mansbach CM, Weinberg RB, Black DD.

J Biol Chem. 2006 Feb 10;281(6):3473-83. Epub 2005 Dec 7.


Functional and morphological assessment of age-related changes in the choroid and outer retina in pigeons.

Fitzgerald ME, Tolley E, Frase S, Zagvazdin Y, Miller RF, Hodos W, Reiner A.

Vis Neurosci. 2001 Mar-Apr;18(2):299-317.


Anterior stromal micropuncture electron microscopic changes in the rabbit cornea.

Judge D, Payant J, Frase S, Wood TO.

Cornea. 1990 Apr;9(2):152-60.


Isolation and characterization of a mucosal triacylglycerol pool undergoing hydrolysis.

Tipton AD 4th, Frase S, Mansbach CM 2nd.

Am J Physiol. 1989 Dec;257(6 Pt 1):G871-8.


Intraenterocyte distribution of absorbed lipid and effects of phosphatidylcholine.

Parlier RD, Frase S, Mansbach CM 2nd.

Am J Physiol. 1989 Feb;256(2 Pt 1):G349-55.


Isolation of the early phase of chylomicron formation in intestinal epithelial cells of rats.

Turner MW, Frase S, Mansbach CM 2nd.

Biochimie. 1988 Sep;70(9):1263-8.


Dietary supplementation with Pluronic L-81 modifies hepatic secretion of very low density lipoproteins in the rat.

Manowitz NR, Tso P, Drake DS, Frase S, Sabesin SM.

J Lipid Res. 1986 Feb;27(2):196-207.


Accumulation of nascent lipoproteins in rat hepatic golgi during induction of fatty liver by orotic acid.

Sabesin SM, Frase S, Ragland JB.

Lab Invest. 1977 Aug;37(2):127-35. No abstract available.


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