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Items: 1 to 50 of 110

1.

The Epstein-Barr Virus BMRF1 Protein Activates Transcription and Inhibits the DNA Damage Response by Binding NuRD.

Salamun SG, Sitz J, De La Cruz-Herrera CF, Yockteng-Melgar J, Marcon E, Greenblatt J, Fradet-Turcotte A, Frappier L.

J Virol. 2019 Aug 28. pii: JVI.01070-19. doi: 10.1128/JVI.01070-19. [Epub ahead of print]

PMID:
31462557
2.

Identification of ARKL1 as a Negative Regulator of Epstein-Barr Virus Reactivation.

Siddiqi UZ, Vaidya AS, Li X, Marcon E, Tsao SW, Greenblatt J, Frappier L.

J Virol. 2019 Jul 24. pii: JVI.00989-19. doi: 10.1128/JVI.00989-19. [Epub ahead of print]

PMID:
31341047
3.

USP7 Regulates Cytokinesis through FBXO38 and KIF20B.

Georges A, Coyaud E, Marcon E, Greenblatt J, Raught B, Frappier L.

Sci Rep. 2019 Feb 25;9(1):2724. doi: 10.1038/s41598-019-39368-y.

4.

Epstein-Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity.

Cheng AZ, Yockteng-Melgar J, Jarvis MC, Malik-Soni N, Borozan I, Carpenter MA, McCann JL, Ebrahimi D, Shaban NM, Marcon E, Greenblatt J, Brown WL, Frappier L, Harris RS.

Nat Microbiol. 2019 Jan;4(1):78-88. doi: 10.1038/s41564-018-0284-6. Epub 2018 Nov 12.

5.

Identification and Characterization of USP7 Targets in Cancer Cells.

Georges A, Marcon E, Greenblatt J, Frappier L.

Sci Rep. 2018 Oct 26;8(1):15833. doi: 10.1038/s41598-018-34197-x.

6.

A genome-wide screen of Epstein-Barr virus proteins that modulate host SUMOylation identifies a SUMO E3 ligase conserved in herpesviruses.

De La Cruz-Herrera CF, Shire K, Siddiqi UZ, Frappier L.

PLoS Pathog. 2018 Jul 6;14(7):e1007176. doi: 10.1371/journal.ppat.1007176. eCollection 2018 Jul.

7.

A Screen for Epstein-Barr Virus Proteins That Inhibit the DNA Damage Response Reveals a Novel Histone Binding Protein.

Ho TH, Sitz J, Shen Q, Leblanc-Lacroix A, Campos EI, Borozan I, Marcon E, Greenblatt J, Fradet-Turcotte A, Jin DY, Frappier L.

J Virol. 2018 Jun 29;92(14). pii: e00262-18. doi: 10.1128/JVI.00262-18. Print 2018 Jul 15.

8.

Correction for Borozan et al., "Analysis of Epstein-Barr Virus Genomes and Expression Profiles in Gastric Adenocarcinoma".

Borozan I, Zapatka M, Frappier L, Ferretti V.

J Virol. 2018 Apr 27;92(10). pii: e00330-18. doi: 10.1128/JVI.00330-18. Print 2018 May 15. No abstract available.

9.

Expression of flavivirus capsids enhance the cellular environment for viral replication by activating Akt-signalling pathways.

Airo AM, Urbanowski MD, Lopez-Orozco J, You JH, Skene-Arnold TD, Holmes C, Yamshchikov V, Malik-Soni N, Frappier L, Hobman TC.

Virology. 2018 Mar;516:147-157. doi: 10.1016/j.virol.2018.01.009. Epub 2018 Jan 19.

10.

Analysis of Epstein-Barr Virus Genomes and Expression Profiles in Gastric Adenocarcinoma.

Borozan I, Zapatka M, Frappier L, Ferretti V.

J Virol. 2018 Jan 2;92(2). pii: e01239-17. doi: 10.1128/JVI.01239-17. Print 2018 Jan 15. Erratum in: J Virol. 2018 Apr 27;92 (10 ):.

11.
12.

Changes in the Maintenance of Certification (MOC) process have not gone far enough.

Frappier L.

R I Med J (2013). 2016 Oct 4;99(10):9. No abstract available.

PMID:
27706269
13.

Identification of RNF168 as a PML nuclear body regulator.

Shire K, Wong AI, Tatham MH, Anderson OF, Ripsman D, Gulstene S, Moffat J, Hay RT, Frappier L.

J Cell Sci. 2016 Feb 1;129(3):580-91. doi: 10.1242/jcs.176446. Epub 2015 Dec 16.

14.

EBNA1.

Frappier L.

Curr Top Microbiol Immunol. 2015;391:3-34. doi: 10.1007/978-3-319-22834-1_1. Review.

PMID:
26428370
15.

Flavivirus Infection Impairs Peroxisome Biogenesis and Early Antiviral Signaling.

You J, Hou S, Malik-Soni N, Xu Z, Kumar A, Rachubinski RA, Frappier L, Hobman TC.

J Virol. 2015 Dec;89(24):12349-61. doi: 10.1128/JVI.01365-15. Epub 2015 Sep 30.

16.

Correction for Malik-Soni and Frappier, Proteomic Profiling of EBNA1-Host Protein Interactions in Latent and Lytic Epstein-Barr Virus Infections.

Malik-Soni N, Frappier L.

J Virol. 2015 Sep;89(17):9143. doi: 10.1128/JVI.01581-15. No abstract available.

17.

Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.

Marcon E, Jain H, Bhattacharya A, Guo H, Phanse S, Pu S, Byram G, Collins BC, Dowdell E, Fenner M, Guo X, Hutchinson A, Kennedy JJ, Krastins B, Larsen B, Lin ZY, Lopez MF, Loppnau P, Miersch S, Nguyen T, Olsen JB, Paduch M, Ravichandran M, Seitova A, Vadali G, Vogelsang MS, Whiteaker JR, Zhong G, Zhong N, Zhao L, Aebersold R, Arrowsmith CH, Emili A, Frappier L, Gingras AC, Gstaiger M, Paulovich AG, Koide S, Kossiakoff AA, Sidhu SS, Wodak SJ, Gräslund S, Greenblatt JF, Edwards AM.

Nat Methods. 2015 Aug;12(8):725-31. doi: 10.1038/nmeth.3472. Epub 2015 Jun 29.

PMID:
26121405
18.

Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7.

Pfoh R, Lacdao IK, Georges AA, Capar A, Zheng H, Frappier L, Saridakis V.

PLoS Pathog. 2015 Jun 5;11(6):e1004950. doi: 10.1371/journal.ppat.1004950. eCollection 2015 Jun.

19.

Proteomics methods for discovering viral-host interactions.

Georges AA, Frappier L.

Methods. 2015 Nov 15;90:21-7. doi: 10.1016/j.ymeth.2015.05.001. Epub 2015 May 7. Review.

PMID:
25959231
20.

Regulation of herpesvirus reactivation by host microRNAs.

Frappier L.

J Virol. 2015 Mar;89(5):2456-8. doi: 10.1128/JVI.03413-14. Epub 2014 Dec 24. Review.

21.

Epstein-Barr virus EBNA1 protein regulates viral latency through effects on let-7 microRNA and dicer.

Mansouri S, Pan Q, Blencowe BJ, Claycomb JM, Frappier L.

J Virol. 2014 Oct;88(19):11166-77. doi: 10.1128/JVI.01785-14. Epub 2014 Jul 16.

22.

Identification of herpesvirus proteins that contribute to G1/S arrest.

Paladino P, Marcon E, Greenblatt J, Frappier L.

J Virol. 2014 Apr;88(8):4480-92. doi: 10.1128/JVI.00059-14. Epub 2014 Feb 5.

23.

Nucleophosmin contributes to the transcriptional activation function of the Epstein-Barr virus EBNA1 protein.

Malik-Soni N, Frappier L.

J Virol. 2014 Feb;88(4):2323-6. doi: 10.1128/JVI.02521-13. Epub 2013 Nov 27.

24.

Identification of a novel protein interaction motif in the regulatory subunit of casein kinase 2.

Cao JY, Shire K, Landry C, Gish GD, Pawson T, Frappier L.

Mol Cell Biol. 2014 Jan;34(2):246-58. doi: 10.1128/MCB.00968-13. Epub 2013 Nov 11.

25.

A role for USP7 in DNA replication.

Jagannathan M, Nguyen T, Gallo D, Luthra N, Brown GW, Saridakis V, Frappier L.

Mol Cell Biol. 2014 Jan;34(1):132-45. doi: 10.1128/MCB.00639-13. Epub 2013 Nov 4.

26.

A cancer-associated Epstein-Barr virus variant with epithelial tropism.

Frappier L.

Trends Microbiol. 2013 Dec;21(12):616-7. doi: 10.1016/j.tim.2013.10.007. Epub 2013 Oct 29.

PMID:
24183509
27.

A role for the nucleosome assembly proteins TAF-Iβ and NAP1 in the activation of BZLF1 expression and Epstein-Barr virus reactivation.

Mansouri S, Wang S, Frappier L.

PLoS One. 2013 May 14;8(5):e63802. doi: 10.1371/journal.pone.0063802. Print 2013.

28.

Ubiquitin-specific protease 7 is a regulator of ubiquitin-conjugating enzyme UbE2E1.

Sarkari F, Wheaton K, La Delfa A, Mohamed M, Shaikh F, Khatun R, Arrowsmith CH, Frappier L, Saridakis V, Sheng Y.

J Biol Chem. 2013 Jun 7;288(23):16975-85. doi: 10.1074/jbc.M113.469262. Epub 2013 Apr 19.

29.

Contributions of Epstein-Barr nuclear antigen 1 (EBNA1) to cell immortalization and survival.

Frappier L.

Viruses. 2012 Sep;4(9):1537-47. doi: 10.3390/v4091537. Epub 2012 Sep 13. Review.

30.

EBNA1 and host factors in Epstein-Barr virus latent DNA replication.

Frappier L.

Curr Opin Virol. 2012 Dec;2(6):733-9. doi: 10.1016/j.coviro.2012.09.005. Epub 2012 Sep 30. Review.

PMID:
23031715
31.

Interactions of the human MCM-BP protein with MCM complex components and Dbf4.

Nguyen T, Jagannathan M, Shire K, Frappier L.

PLoS One. 2012;7(4):e35931. doi: 10.1371/journal.pone.0035931. Epub 2012 Apr 23.

32.

Proteomic profiling of EBNA1-host protein interactions in latent and lytic Epstein-Barr virus infections.

Malik-Soni N, Frappier L.

J Virol. 2012 Jun;86(12):6999-7002. doi: 10.1128/JVI.00194-12. Epub 2012 Apr 11. Erratum in: J Virol. 2015 Sep;89(17):9143.

33.

Functions of the Epstein-Barr virus EBNA1 protein in viral reactivation and lytic infection.

Sivachandran N, Wang X, Frappier L.

J Virol. 2012 Jun;86(11):6146-58. doi: 10.1128/JVI.00013-12. Epub 2012 Apr 4.

34.

The MCM-associated protein MCM-BP is important for human nuclear morphology.

Jagannathan M, Sakwe AM, Nguyen T, Frappier L.

J Cell Sci. 2012 Jan 1;125(Pt 1):133-43. doi: 10.1242/jcs.089938. Epub 2012 Jan 16.

35.

The Epstein-Barr Virus EBNA1 Protein.

Frappier L.

Scientifica (Cairo). 2012;2012:438204. doi: 10.6064/2012/438204. Epub 2012 Dec 19. Review.

36.

Role of EBNA1 in NPC tumourigenesis.

Frappier L.

Semin Cancer Biol. 2012 Apr;22(2):154-61. doi: 10.1016/j.semcancer.2011.12.002. Epub 2011 Dec 22. Review.

PMID:
22206863
37.

Proteomic profiling of the human cytomegalovirus UL35 gene products reveals a role for UL35 in the DNA repair response.

Salsman J, Jagannathan M, Paladino P, Chan PK, Dellaire G, Raught B, Frappier L.

J Virol. 2012 Jan;86(2):806-20. doi: 10.1128/JVI.05442-11. Epub 2011 Nov 9.

38.
39.

Contributions of the Epstein-Barr virus EBNA1 protein to gastric carcinoma.

Sivachandran N, Dawson CW, Young LS, Liu FF, Middeldorp J, Frappier L.

J Virol. 2012 Jan;86(1):60-8. doi: 10.1128/JVI.05623-11. Epub 2011 Oct 19.

40.

Epstein-Barr virus nuclear antigen 1 replication and segregation functions in nasopharyngeal carcinoma cell lines.

Sivachandran N, Thawe NN, Frappier L.

J Virol. 2011 Oct;85(19):10425-30. doi: 10.1128/JVI.05293-11. Epub 2011 Jul 27.

41.

Nuclear body formation and PML body remodeling by the human cytomegalovirus protein UL35.

Salsman J, Wang X, Frappier L.

Virology. 2011 Jun 5;414(2):119-29. doi: 10.1016/j.virol.2011.03.013. Epub 2011 Apr 13.

42.

Gene expression control by protein deubiquitinases.

Frappier L, Verrijzer CP.

Curr Opin Genet Dev. 2011 Apr;21(2):207-13. doi: 10.1016/j.gde.2011.02.005. Epub 2011 Mar 14. Review.

PMID:
21411309
43.

The herpesvirus associated ubiquitin specific protease, USP7, is a negative regulator of PML proteins and PML nuclear bodies.

Sarkari F, Wang X, Nguyen T, Frappier L.

PLoS One. 2011 Jan 31;6(1):e16598. doi: 10.1371/journal.pone.0016598.

44.

Nucleolar targeting of the fbw7 ubiquitin ligase by a pseudosubstrate and glycogen synthase kinase 3.

Welcker M, Larimore EA, Frappier L, Clurman BE.

Mol Cell Biol. 2011 Mar;31(6):1214-24. doi: 10.1128/MCB.01347-10. Epub 2011 Jan 10.

45.

Viral disruption of promyelocytic leukemia (PML) nuclear bodies by hijacking host PML regulators.

Frappier L.

Virulence. 2011 Jan-Feb;2(1):58-62. Epub 2011 Jan 1.

PMID:
21217204
46.

MCM-BP regulates unloading of the MCM2-7 helicase in late S phase.

Nishiyama A, Frappier L, Méchali M.

Genes Dev. 2011 Jan 15;25(2):165-75. doi: 10.1101/gad.614411. Epub 2010 Dec 31.

47.

USP7/HAUSP promotes the sequence-specific DNA binding activity of p53.

Sarkari F, Sheng Y, Frappier L.

PLoS One. 2010 Sep 27;5(9):e13040. doi: 10.1371/journal.pone.0013040.

48.

Epstein-Barr virus nuclear antigen 1 Hijacks the host kinase CK2 to disrupt PML nuclear bodies.

Sivachandran N, Cao JY, Frappier L.

J Virol. 2010 Nov;84(21):11113-23. doi: 10.1128/JVI.01183-10. Epub 2010 Aug 18.

49.

Further insight into substrate recognition by USP7: structural and biochemical analysis of the HdmX and Hdm2 interactions with USP7.

Sarkari F, La Delfa A, Arrowsmith CH, Frappier L, Sheng Y, Saridakis V.

J Mol Biol. 2010 Oct 8;402(5):825-37. doi: 10.1016/j.jmb.2010.08.017. Epub 2010 Aug 14.

PMID:
20713061
50.

Mitotic chromosome interactions of Epstein-Barr nuclear antigen 1 (EBNA1) and human EBNA1-binding protein 2 (EBP2).

Nayyar VK, Shire K, Frappier L.

J Cell Sci. 2009 Dec 1;122(Pt 23):4341-50. doi: 10.1242/jcs.060913. Epub 2009 Nov 3.

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