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Items: 42

1.

Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by improving the magnitude and quality of cytotoxic T cells.

Foy SP, Mandl SJ, dela Cruz T, Cote JJ, Gordon EJ, Trent E, Delcayre A, Breitmeyer J, Franzusoff A, Rountree RB.

Cancer Immunol Immunother. 2016 May;65(5):537-49. doi: 10.1007/s00262-016-1816-7. Epub 2016 Mar 10.

2.

Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice.

Foy SP, Sennino B, dela Cruz T, Cote JJ, Gordon EJ, Kemp F, Xavier V, Franzusoff A, Rountree RB, Mandl SJ.

PLoS One. 2016 Feb 24;11(2):e0150084. doi: 10.1371/journal.pone.0150084. eCollection 2016.

3.

Elucidating immunologic mechanisms of PROSTVAC cancer immunotherapy.

Mandl SJ, Rountree RB, Dela Cruz TB, Foy SP, Cote JJ, Gordon EJ, Trent E, Delcayre A, Franzusoff A.

J Immunother Cancer. 2014 Oct 14;2(1):34. doi: 10.1186/s40425-014-0034-0. eCollection 2014.

4.

Mutation-specific control of BCR-ABL T315I positive leukemia with a recombinant yeast-based therapeutic vaccine in a murine model.

Bui MR, Hodson V, King T, Leopold D, Dai S, Fiolkoski V, Oakes S, Duke R, Apelian D, Franzusoff A, DeGregori J.

Vaccine. 2010 Aug 23;28(37):6028-35. doi: 10.1016/j.vaccine.2010.06.085. Epub 2010 Jul 7.

5.

Concurrent vaccination with two distinct vaccine platforms targeting the same antigen generates phenotypically and functionally distinct T-cell populations.

Boehm AL, Higgins J, Franzusoff A, Schlom J, Hodge JW.

Cancer Immunol Immunother. 2010 Mar;59(3):397-408. doi: 10.1007/s00262-009-0759-7. Epub 2009 Sep 16.

6.

Human dendritic cell maturation and activation by a heat-killed recombinant yeast (Saccharomyces cerevisiae) vector encoding carcinoembryonic antigen.

Remondo C, Cereda V, Mostböck S, Sabzevari H, Franzusoff A, Schlom J, Tsang KY.

Vaccine. 2009 Feb 11;27(7):987-94. doi: 10.1016/j.vaccine.2008.12.002. Epub 2008 Dec 25.

7.

Vaccination with a recombinant Saccharomyces cerevisiae expressing a tumor antigen breaks immune tolerance and elicits therapeutic antitumor responses.

Wansley EK, Chakraborty M, Hance KW, Bernstein MB, Boehm AL, Guo Z, Quick D, Franzusoff A, Greiner JW, Schlom J, Hodge JW.

Clin Cancer Res. 2008 Jul 1;14(13):4316-25. doi: 10.1158/1078-0432.CCR-08-0393.

8.

Recombinant Saccharomyces cerevisiae (yeast-CEA) as a potent activator of murine dendritic cells.

Bernstein MB, Chakraborty M, Wansley EK, Guo Z, Franzusoff A, Mostböck S, Sabzevari H, Schlom J, Hodge JW.

Vaccine. 2008 Jan 24;26(4):509-21. Epub 2007 Dec 3.

PMID:
18155327
9.

Generation of a prophylactic melanoma vaccine using whole recombinant yeast expressing MART-1.

Riemann H, Takao J, Shellman YG, Hines WA, Edwards CK 3rd, Franzusoff A, Norris DA, Fujita M.

Exp Dermatol. 2007 Oct;16(10):814-22. Erratum in: Exp Dermatol. 2008 Apr;17(4):372. Franzusoff, Alex [added].

PMID:
17845213
10.

Whole recombinant yeast-based immunotherapy induces potent T cell responses targeting HCV NS3 and Core proteins.

Haller AA, Lauer GM, King TH, Kemmler C, Fiolkoski V, Lu Y, Bellgrau D, Rodell TC, Apelian D, Franzusoff A, Duke RC.

Vaccine. 2007 Feb 9;25(8):1452-63. Epub 2006 Nov 10.

PMID:
17098335
11.

TGF-beta2 inhibition augments the effect of tumor vaccine and improves the survival of animals with pre-established brain tumors.

Liu Y, Wang Q, Kleinschmidt-DeMasters BK, Franzusoff A, Ng KY, Lillehei KO.

J Neurooncol. 2007 Jan;81(2):149-62. Epub 2006 Aug 29.

PMID:
16941073
12.

Yeasts encoding tumour antigens in cancer immunotherapy.

Franzusoff A, Duke RC, King TH, Lu Y, Rodell TC.

Expert Opin Biol Ther. 2005 Apr;5(4):565-75. Review.

PMID:
15934834
13.

Mutation-selective tumor remission with Ras-targeted, whole yeast-based immunotherapy.

Lu Y, Bellgrau D, Dwyer-Nield LD, Malkinson AM, Duke RC, Rodell TC, Franzusoff A.

Cancer Res. 2004 Aug 1;64(15):5084-8.

14.

Fas ligand-dependent suppression of autoimmunity via recruitment and subsequent termination of activated T cells.

Modiano JF, Sun J, Lang J, Vacano G, Patterson D, Chan D, Franzusoff A, Gianani R, Meech SJ, Duke R, Bellgrau D.

Clin Immunol. 2004 Jul;112(1):54-65.

PMID:
15207782
15.

Epidermal growth factor receptor mediates silibinin-induced cytotoxicity in a rat glioma cell line.

Qi L, Singh RP, Lu Y, Agarwal R, Harrison GS, Franzusoff A, Glode LM.

Cancer Biol Ther. 2003 Sep-Oct;2(5):526-31.

PMID:
14614320
16.

Cell surface expression of the HIV-1 envelope glycoproteins is directed from intracellular CTLA-4-containing regulated secretory granules.

Miranda LR, Schaefer BC, Kupfer A, Hu Z, Franzusoff A.

Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8031-6.

17.

Furin proteolytically processes the heparin-binding region of extracellular superoxide dismutase.

Bowler RP, Nicks M, Olsen DA, Thøgersen IB, Valnickova Z, Højrup P, Franzusoff A, Enghild JJ, Crapo JD.

J Biol Chem. 2002 May 10;277(19):16505-11. Epub 2002 Feb 22.

18.

Whole recombinant yeast vaccine activates dendritic cells and elicits protective cell-mediated immunity.

Stubbs AC, Martin KS, Coeshott C, Skaates SV, Kuritzkes DR, Bellgrau D, Franzusoff A, Duke RC, Wilson CC.

Nat Med. 2001 May;7(5):625-9.

PMID:
11329066
19.

Sec7p directs the transitions required for yeast Golgi biogenesis.

Deitz SB, Rambourg A, Képès F, Franzusoff A.

Traffic. 2000 Feb;1(2):172-83.

20.

Morphogenesis and dynamics of the yeast Golgi apparatus.

Morin-Ganet MN, Rambourg A, Deitz SB, Franzusoff A, Képès F.

Traffic. 2000 Jan;1(1):56-68.

21.
22.

Genetic interactions in yeast between Ypt GTPases and Arf guanine nucleotide exchangers.

Jones S, Jedd G, Kahn RA, Franzusoff A, Bartolini F, Segev N.

Genetics. 1999 Aug;152(4):1543-56.

23.

Endocytic delivery of intramolecularly quenched substrates and inhibitors to the intracellular yeast Kex2 protease1.

Henkel MK, Pott G, Henkel AW, Juliano L, Kam CM, Powers JC, Franzusoff A.

Biochem J. 1999 Jul 15;341 ( Pt 2):445-52.

24.

An N-end rule destabilization mutant reveals pre-Golgi requirements for Sec7p in yeast membrane traffic.

Wolf J, Nicks M, Deitz S, van Tuinen E, Franzusoff A.

Biochem Biophys Res Commun. 1998 Feb 4;243(1):191-8.

PMID:
9473503
25.

Isolation of the human PC6 gene encoding the putative host protease for HIV-1 gp160 processing in CD4+ T lymphocytes.

Miranda L, Wolf J, Pichuantes S, Duke R, Franzusoff A.

Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):7695-700.

26.

The putative membrane anchor protein for yeast Sec7p recruitment.

Wolf JR, Lasher RS, Franzusoff A.

Biochem Biophys Res Commun. 1996 Jul 5;224(1):126-33.

PMID:
8694799
27.

Human ARF4 expression rescues sec7 mutant yeast cells.

Deitz SB, Wu C, Silve S, Howell KE, Melançon P, Kahn RA, Franzusoff A.

Mol Cell Biol. 1996 Jul;16(7):3275-84.

28.

A role for CD95 ligand in preventing graft rejection.

Bellgrau D, Gold D, Selawry H, Moore J, Franzusoff A, Duke RC.

Nature. 1995 Oct 19;377(6550):630-2. Erratum in: Nature 1998 Jul 9;394(6689):133.

PMID:
7566174
29.

Biochemical and genetic definition of the cellular protease required for HIV-1 gp160 processing.

Franzusoff A, Volpe AM, Josse D, Pichuantes S, Wolf JR.

J Biol Chem. 1995 Feb 17;270(7):3154-9.

30.
31.

Beauty and the yeast: compartmental organization of the secretory pathway.

Franzusoff A.

Semin Cell Biol. 1992 Oct;3(5):309-24. Review.

PMID:
1457775
32.

Characterization of the Saccharomyces Golgi complex through the cell cycle by immunoelectron microscopy.

Preuss D, Mulholland J, Franzusoff A, Segev N, Botstein D.

Mol Biol Cell. 1992 Jul;3(7):789-803.

33.

Immuno-isolation of Sec7p-coated transport vesicles from the yeast secretory pathway.

Franzusoff A, Lauzé E, Howell KE.

Nature. 1992 Jan 9;355(6356):173-5.

PMID:
1729652
34.

Vesicle budding: insights from cell-free assays.

Melançon P, Franzusoff A, Howell KE.

Trends Cell Biol. 1991 Dec;1(6):165-71.

PMID:
14731860
35.

Analysis of polypeptide transit through yeast secretory pathway.

Franzusoff A, Rothblatt J, Schekman R.

Methods Enzymol. 1991;194:662-74. No abstract available.

PMID:
2005814
36.

Localization of components involved in protein transport and processing through the yeast Golgi apparatus.

Franzusoff A, Redding K, Crosby J, Fuller RS, Schekman R.

J Cell Biol. 1991 Jan;112(1):27-37.

37.
38.

SEC7 encodes an unusual, high molecular weight protein required for membrane traffic from the yeast Golgi apparatus.

Achstetter T, Franzusoff A, Field C, Schekman R.

J Biol Chem. 1988 Aug 25;263(24):11711-7.

39.
40.

Insulinomimetic homology of concanavalin A.

Franzusoff AJ.

Med Hypotheses. 1983 Mar;10(3):223-8.

PMID:
6348492
41.

Uptake and phosphorylation of 2-deoxy-D-glucose by wild-type and single-kinase strains of Saccharomyces cerevisiae.

Franzusoff A, Cirillo VP.

Biochim Biophys Acta. 1982 Jun 14;688(2):295-304.

PMID:
7049241
42.

Alterations in glucose metabolism and its stimulation by insulin in isolated adipose cells during the development of genetic obesity in the Zucker fatty rat.

Cushman SW, Zarnowski MJ, Franzusoff AJ, Salans LB.

Metabolism. 1978 Dec;27(12 Suppl 2):1930-40. No abstract available.

PMID:
723642

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