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Items: 25

1.

Predicting sporadic Alzheimer's disease progression via inherited Alzheimer's disease-informed machine-learning.

Franzmeier N, Koutsouleris N, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, Duering M, Dichgans M, Levin J, Gordon BA, Lim YY, Masters CL, Rossor M, Fox NC, O'Connor A, Chhatwal J, Salloway S, Danek A, Hassenstab J, Schofield PR, Morris JC, Bateman RJ; Alzheimer's disease neuroimaging initiative (ADNI); Dominantly Inherited Alzheimer Network (DIAN), Ewers M.

Alzheimers Dement. 2020 Feb 11. doi: 10.1002/alz.12032. [Epub ahead of print]

PMID:
32043733
2.

Functional brain architecture is associated with the rate of tau accumulation in Alzheimer's disease.

Franzmeier N, Neitzel J, Rubinski A, Smith R, Strandberg O, Ossenkoppele R, Hansson O, Ewers M; Alzheimer’s Disease Neuroimaging Initiative (ADNI).

Nat Commun. 2020 Jan 17;11(1):347. doi: 10.1038/s41467-019-14159-1.

3.

Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease.

Ewers M, Franzmeier N, Suárez-Calvet M, Morenas-Rodriguez E, Caballero MAA, Kleinberger G, Piccio L, Cruchaga C, Deming Y, Dichgans M, Trojanowski JQ, Shaw LM, Weiner MW, Haass C; Alzheimer’s Disease Neuroimaging Initiative.

Sci Transl Med. 2019 Aug 28;11(507). pii: eaav6221. doi: 10.1126/scitranslmed.aav6221.

PMID:
31462511
4.

Connectomics and molecular imaging in neurodegeneration.

Bischof GN, Ewers M, Franzmeier N, Grothe MJ, Hoenig M, Kocagoncu E, Neitzel J, Rowe JB, Strafella A, Drzezga A, van Eimeren T; MINC faculty.

Eur J Nucl Med Mol Imaging. 2019 Dec;46(13):2819-2830. doi: 10.1007/s00259-019-04394-5. Epub 2019 Jul 11.

PMID:
31292699
5.

Left frontal connectivity attenuates the adverse effect of entorhinal tau pathology on memory.

Neitzel J, Franzmeier N, Rubinski A, Ewers M; Alzheimer's Disease Neuroimaging Initiative (ADNI).

Neurology. 2019 Jul 23;93(4):e347-e357. doi: 10.1212/WNL.0000000000007822. Epub 2019 Jun 24.

PMID:
31235661
6.

The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory.

Franzmeier N, Rubinski A, Neitzel J, Ewers M; Alzheimer’s Disease Neuroimaging Initiative (ADNI).

Nat Commun. 2019 Apr 16;10(1):1766. doi: 10.1038/s41467-019-09564-5.

7.

The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.

Franzmeier N, Ren J, Damm A, Monté-Rubio G, Boada M, Ruiz A, Ramirez A, Jessen F, Düzel E, Rodríguez Gómez O, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, Buerger K, Levin J, Duering M, Dichgans M, Suárez-Calvet M, Haass C, Gordon BA, Lim YY, Masters CL, Janowitz D, Catak C, Wolfsgruber S, Wagner M, Milz E, Moreno-Grau S, Teipel S, Grothe MJ, Kilimann I, Rossor M, Fox N, Laske C, Chhatwal J, Falkai P, Perneczky R, Lee JH, Spottke A, Boecker H, Brosseron F, Fliessbach K, Heneka MT, Nestor P, Peters O, Fuentes M, Menne F, Priller J, Spruth EJ, Franke C, Schneider A, Westerteicher C, Speck O, Wiltfang J, Bartels C, Araque Caballero MÁ, Metzger C, Bittner D, Salloway S, Danek A, Hassenstab J, Yakushev I, Schofield PR, Morris JC, Bateman RJ, Ewers M.

Mol Psychiatry. 2019 Mar 21. doi: 10.1038/s41380-019-0404-6. [Epub ahead of print]

8.

Functional connectivity associated with tau levels in ageing, Alzheimer's, and small vessel disease.

Franzmeier N, Rubinski A, Neitzel J, Kim Y, Damm A, Na DL, Kim HJ, Lyoo CH, Cho H, Finsterwalder S, Duering M, Seo SW, Ewers M; Alzheimer’s Disease Neuroimaging Initiative.

Brain. 2019 Apr 1;142(4):1093-1107. doi: 10.1093/brain/awz026.

PMID:
30770704
9.

Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology.

Suárez-Calvet M, Morenas-Rodríguez E, Kleinberger G, Schlepckow K, Araque Caballero MÁ, Franzmeier N, Capell A, Fellerer K, Nuscher B, Eren E, Levin J, Deming Y, Piccio L, Karch CM, Cruchaga C, Shaw LM, Trojanowski JQ, Weiner M, Ewers M, Haass C; Alzheimer’s Disease Neuroimaging Initiative.

Mol Neurodegener. 2019 Jan 10;14(1):1. doi: 10.1186/s13024-018-0301-5.

10.

CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline.

Suárez-Calvet M, Capell A, Araque Caballero MÁ, Morenas-Rodríguez E, Fellerer K, Franzmeier N, Kleinberger G, Eren E, Deming Y, Piccio L, Karch CM, Cruchaga C, Paumier K, Bateman RJ, Fagan AM, Morris JC, Levin J, Danek A, Jucker M, Masters CL, Rossor MN, Ringman JM, Shaw LM, Trojanowski JQ, Weiner M, Ewers M, Haass C; Dominantly Inherited Alzheimer Network; Alzheimer's Disease Neuroimaging Initiative.

EMBO Mol Med. 2018 Dec;10(12). pii: e9712. doi: 10.15252/emmm.201809712.

11.

Correspondence Between Resting-State and Episodic Memory-Task Related Networks in Elderly Subjects.

Simon-Vermot L, Taylor ANW, Araque Caballero MÀ, Franzmeier N, Buerger K, Catak C, Janowitz D, Kambeitz-Ilankovic LM, Ertl-Wagner B, Duering M, Ewers M.

Front Aging Neurosci. 2018 Nov 8;10:362. doi: 10.3389/fnagi.2018.00362. eCollection 2018.

12.

White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease.

Araque Caballero MÁ, Suárez-Calvet M, Duering M, Franzmeier N, Benzinger T, Fagan AM, Bateman RJ, Jack CR, Levin J, Dichgans M, Jucker M, Karch C, Masters CL, Morris JC, Weiner M, Rossor M, Fox NC, Lee JH, Salloway S, Danek A, Goate A, Yakushev I, Hassenstab J, Schofield PR, Haass C, Ewers M.

Brain. 2018 Oct 1;141(10):3065-3080. doi: 10.1093/brain/awy229.

13.

Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance.

Stern Y, Arenaza-Urquijo EM, Bartrés-Faz D, Belleville S, Cantilon M, Chetelat G, Ewers M, Franzmeier N, Kempermann G, Kremen WS, Okonkwo O, Scarmeas N, Soldan A, Udeh-Momoh C, Valenzuela M, Vemuri P, Vuoksimaa E; Reserve, Resilience and Protective Factors PIA Empirical Definitions and Conceptual Frameworks Workgroup.

Alzheimers Dement. 2018 Sep 14. pii: S1552-5260(18)33491-5. doi: 10.1016/j.jalz.2018.07.219. [Epub ahead of print] Review.

PMID:
30222945
14.

Multisensory integration processing during olfactory-visual stimulation-An fMRI graph theoretical network analysis.

Ripp I, Zur Nieden AN, Blankenagel S, Franzmeier N, Lundström JN, Freiherr J.

Hum Brain Mapp. 2018 Sep;39(9):3713-3727. doi: 10.1002/hbm.24206. Epub 2018 May 7.

PMID:
29736907
15.

The left frontal cortex supports reserve in aging by enhancing functional network efficiency.

Franzmeier N, Hartmann J, Taylor ANW, Araque-Caballero MÁ, Simon-Vermot L, Kambeitz-Ilankovic L, Bürger K, Catak C, Janowitz D, Müller C, Ertl-Wagner B, Stahl R, Dichgans M, Duering M, Ewers M.

Alzheimers Res Ther. 2018 Mar 6;10(1):28. doi: 10.1186/s13195-018-0358-y.

16.

Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease.

Franzmeier N, Düzel E, Jessen F, Buerger K, Levin J, Duering M, Dichgans M, Haass C, Suárez-Calvet M, Fagan AM, Paumier K, Benzinger T, Masters CL, Morris JC, Perneczky R, Janowitz D, Catak C, Wolfsgruber S, Wagner M, Teipel S, Kilimann I, Ramirez A, Rossor M, Jucker M, Chhatwal J, Spottke A, Boecker H, Brosseron F, Falkai P, Fliessbach K, Heneka MT, Laske C, Nestor P, Peters O, Fuentes M, Menne F, Priller J, Spruth EJ, Franke C, Schneider A, Kofler B, Westerteicher C, Speck O, Wiltfang J, Bartels C, Araque Caballero MÁ, Metzger C, Bittner D, Weiner M, Lee JH, Salloway S, Danek A, Goate A, Schofield PR, Bateman RJ, Ewers M.

Brain. 2018 Apr 1;141(4):1186-1200. doi: 10.1093/brain/awy008.

17.

Free water determines diffusion alterations and clinical status in cerebral small vessel disease.

Duering M, Finsterwalder S, Baykara E, Tuladhar AM, Gesierich B, Konieczny MJ, Malik R, Franzmeier N, Ewers M, Jouvent E, Biessels GJ, Schmidt R, de Leeuw FE, Pasternak O, Dichgans M.

Alzheimers Dement. 2018 Jun;14(6):764-774. doi: 10.1016/j.jalz.2017.12.007. Epub 2018 Feb 16.

18.

Functional brain network architecture may route progression of Alzheimer's disease pathology.

Franzmeier N, Dyrba M.

Brain. 2017 Dec 1;140(12):3077-3080. doi: 10.1093/brain/awx304. No abstract available.

PMID:
29194505
19.

Resting-State Connectivity of the Left Frontal Cortex to the Default Mode and Dorsal Attention Network Supports Reserve in Mild Cognitive Impairment.

Franzmeier N, Göttler J, Grimmer T, Drzezga A, Áraque-Caballero MA, Simon-Vermot L, Taylor ANW, Bürger K, Catak C, Janowitz D, Müller C, Duering M, Sorg C, Ewers M.

Front Aging Neurosci. 2017 Aug 7;9:264. doi: 10.3389/fnagi.2017.00264. eCollection 2017.

20.

Left Frontal Hub Connectivity during Memory Performance Supports Reserve in Aging and Mild Cognitive Impairment.

Franzmeier N, Hartmann JC, Taylor ANW, Araque Caballero MÁ, Simon-Vermot L, Buerger K, Kambeitz-Ilankovic LM, Ertl-Wagner B, Mueller C, Catak C, Janowitz D, Stahl R, Dichgans M, Duering M, Ewers M.

J Alzheimers Dis. 2017;59(4):1381-1392. doi: 10.3233/JAD-170360.

21.

Left frontal cortex connectivity underlies cognitive reserve in prodromal Alzheimer disease.

Franzmeier N, Duering M, Weiner M, Dichgans M, Ewers M; Alzheimer's Disease Neuroimaging Initiative (ADNI).

Neurology. 2017 Mar 14;88(11):1054-1061. doi: 10.1212/WNL.0000000000003711. Epub 2017 Feb 10.

22.

Robust Detection of Impaired Resting State Functional Connectivity Networks in Alzheimer's Disease Using Elastic Net Regularized Regression.

Teipel SJ, Grothe MJ, Metzger CD, Grimmer T, Sorg C, Ewers M, Franzmeier N, Meisenzahl E, Klöppel S, Borchardt V, Walter M, Dyrba M.

Front Aging Neurosci. 2017 Jan 4;8:318. doi: 10.3389/fnagi.2016.00318. eCollection 2016.

23.

Cognitive reserve moderates the association between functional network anti-correlations and memory in MCI.

Franzmeier N, Buerger K, Teipel S, Stern Y, Dichgans M, Ewers M; Alzheimer's Disease Neuroimaging Initiative (ADNI).

Neurobiol Aging. 2017 Feb;50:152-162. doi: 10.1016/j.neurobiolaging.2016.11.013. Epub 2016 Dec 1.

PMID:
28017480
24.

Resting-state global functional connectivity as a biomarker of cognitive reserve in mild cognitive impairment.

Franzmeier N, Caballero MÁA, Taylor ANW, Simon-Vermot L, Buerger K, Ertl-Wagner B, Mueller C, Catak C, Janowitz D, Baykara E, Gesierich B, Duering M, Ewers M; Alzheimer’s Disease Neuroimaging Initiative.

Brain Imaging Behav. 2017 Apr;11(2):368-382. doi: 10.1007/s11682-016-9599-1.

PMID:
27709513
25.

Tract-specific white matter hyperintensities disrupt neural network function in Alzheimer's disease.

Taylor ANW, Kambeitz-Ilankovic L, Gesierich B, Simon-Vermot L, Franzmeier N, Araque Caballero MÁ, Müller S, Hesheng L, Ertl-Wagner B, Bürger K, Weiner MW, Dichgans M, Duering M, Ewers M; Alzheimer's Disease Neuroimaging Initiative (ADNI).

Alzheimers Dement. 2017 Mar;13(3):225-235. doi: 10.1016/j.jalz.2016.06.2358. Epub 2016 Jul 16.

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