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Items: 37

1.

Klotho: An Elephant in Aging Research.

Cheikhi A, Barchowsky A, Sahu A, Shinde SN, Pius A, Clemens ZJ, Li H, Kennedy CA, Hoeck JD, Franti M, Ambrosio F.

J Gerontol A Biol Sci Med Sci. 2019 Jun 18;74(7):1031-1042. doi: 10.1093/gerona/glz061.

PMID:
30843026
2.

GDF11 Decreases Pressure Overload-Induced Hypertrophy, but Can Cause Severe Cachexia and Premature Death.

Harper SC, Johnson J, Borghetti G, Zhao H, Wang T, Wallner M, Kubo H, Feldsott EA, Yang Y, Joo Y, Gou X, Sabri AK, Gupta P, Myzithras M, Khalil A, Franti M, Houser SR.

Circ Res. 2018 Nov 9;123(11):1220-1231. doi: 10.1161/CIRCRESAHA.118.312955.

3.

Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration.

Sahu A, Mamiya H, Shinde SN, Cheikhi A, Winter LL, Vo NV, Stolz D, Roginskaya V, Tang WY, St Croix C, Sanders LH, Franti M, Van Houten B, Rando TA, Barchowsky A, Ambrosio F.

Nat Commun. 2018 Nov 19;9(1):4859. doi: 10.1038/s41467-018-07253-3.

4.

GDF11 Treatment Attenuates the Recovery of Skeletal Muscle Function After Injury in Older Rats.

Zhou Y, Sharma N, Dukes D, Myzithras MB, Gupta P, Khalil A, Kahn J, Ahlberg JS, Hayes DB, Franti M, Criswell T.

AAPS J. 2017 Mar;19(2):431-437. doi: 10.1208/s12248-016-0024-x. Epub 2016 Dec 6.

PMID:
27924614
5.

High-Throughput Small Interfering RNA Screening Identifies Phosphatidylinositol 3-Kinase Class II Alpha as Important for Production of Human Cytomegalovirus Virions.

Polachek WS, Moshrif HF, Franti M, Coen DM, Sreenu VB, Strang BL.

J Virol. 2016 Aug 26;90(18):8360-71. doi: 10.1128/JVI.01134-16. Print 2016 Sep 15.

6.

Differential Binding Activity of TGF-β Family Proteins to Select TGF-β Receptors.

Khalil AM, Dotimas H, Kahn J, Lamerdin JE, Hayes DB, Gupta P, Franti M.

J Pharmacol Exp Ther. 2016 Sep;358(3):423-30. doi: 10.1124/jpet.116.232322. Epub 2016 Jun 23.

PMID:
27340210
7.

Discovery of Potent, Orally Bioavailable Inhibitors of Human Cytomegalovirus.

Fader L, Brault M, Desjardins J, Dansereau N, Lamorte L, Tremblay S, Bilodeau F, Bordeleau J, Duplessis M, Gorys V, Gillard J, Gleason JL, James C, Joly MA, Kuhn C, Llinas-Brunet M, Luo L, Morency L, Morin S, Parisien M, Poirier M, Thibeault C, Trinh T, Sturino C, Srivastava S, Yoakim C, Franti M.

ACS Med Chem Lett. 2016 Mar 1;7(5):525-30. doi: 10.1021/acsmedchemlett.6b00064. eCollection 2016 May 12.

8.

Is Growth Differentiation Factor 11 a Realistic Therapeutic for Aging-Dependent Muscle Defects?

Harper SC, Brack A, MacDonnell S, Franti M, Olwin BB, Bailey BA, Rudnicki MA, Houser SR.

Circ Res. 2016 Apr 1;118(7):1143-50; discussion 1150. doi: 10.1161/CIRCRESAHA.116.307962.

9.

Crystal structure of human GDF11.

Padyana AK, Vaidialingam B, Hayes DB, Gupta P, Franti M, Farrow NA.

Acta Crystallogr F Struct Biol Commun. 2016 Mar;72(Pt 3):160-4. doi: 10.1107/S2053230X16001588. Epub 2016 Feb 16.

10.

Development of an ultra-sensitive Simoa assay to enable GDF11 detection: a comparison across bioanalytical platforms.

Myzithras M, Li H, Bigwarfe T, Waltz E, Gupta P, Low S, Hayes DB, MacDonnell S, Ahlberg J, Franti M, Roberts S.

Bioanalysis. 2016 Mar;8(6):511-8. doi: 10.4155/bio.16.17. Epub 2016 Feb 26.

PMID:
26917343
11.

GDF11 does not rescue aging-related pathological hypertrophy.

Smith SC, Zhang X, Zhang X, Gross P, Starosta T, Mohsin S, Franti M, Gupta P, Hayes D, Myzithras M, Kahn J, Tanner J, Weldon SM, Khalil A, Guo X, Sabri A, Chen X, MacDonnell S, Houser SR.

Circ Res. 2015 Nov 6;117(11):926-32. doi: 10.1161/CIRCRESAHA.115.307527. Epub 2015 Sep 17.

12.

RNASEK Is a V-ATPase-Associated Factor Required for Endocytosis and the Replication of Rhinovirus, Influenza A Virus, and Dengue Virus.

Perreira JM, Aker AM, Savidis G, Chin CR, McDougall WM, Portmann JM, Meraner P, Smith MC, Rahman M, Baker RE, Gauthier A, Franti M, Brass AL.

Cell Rep. 2015 Aug 4;12(5):850-63. doi: 10.1016/j.celrep.2015.06.076. Epub 2015 Jul 23.

13.

Development of a high-throughput human cytomegalovirus quantitative PCR cell-based assay.

Tremblay S, Dansereau N, Balsitis S, Franti M, Lamorte L.

J Virol Methods. 2014 Jan;195:67-71. doi: 10.1016/j.jviromet.2013.09.008. Epub 2013 Oct 4.

PMID:
24100066
14.

Neutralizing antibodies are unable to inhibit direct viral cell-to-cell spread of human cytomegalovirus.

Jacob CL, Lamorte L, Sepulveda E, Lorenz IC, Gauthier A, Franti M.

Virology. 2013 Sep;444(1-2):140-7. doi: 10.1016/j.virol.2013.06.002. Epub 2013 Jul 9.

15.

Phosphatidylinositol 4-kinase III beta is essential for replication of human rhinovirus and its inhibition causes a lethal phenotype in vivo.

Spickler C, Lippens J, Laberge MK, Desmeules S, Bellavance É, Garneau M, Guo T, Hucke O, Leyssen P, Neyts J, Vaillancourt FH, Décor A, O'Meara J, Franti M, Gauthier A.

Antimicrob Agents Chemother. 2013 Jul;57(7):3358-68. doi: 10.1128/AAC.00303-13. Epub 2013 May 6.

16.

Vectored co-delivery of human cytomegalovirus gH and gL proteins elicits potent complement-independent neutralizing antibodies.

Loomis RJ, Lilja AE, Monroe J, Balabanis KA, Brito LA, Palladino G, Franti M, Mandl CW, Barnett SW, Mason PW.

Vaccine. 2013 Jan 30;31(6):919-26. doi: 10.1016/j.vaccine.2012.12.009. Epub 2012 Dec 14.

PMID:
23246547
17.

Elicitation of neutralizing antibodies directed against CD4-induced epitope(s) using a CD4 mimetic cross-linked to a HIV-1 envelope glycoprotein.

Dey AK, Burke B, Sun Y, Sirokman K, Nandi A, Hartog K, Lian Y, Geonnotti AR, Montefiori D, Franti M, Martin G, Carfi A, Kessler P, Martin L, Srivastava IK, Barnett SW.

PLoS One. 2012;7(1):e30233. doi: 10.1371/journal.pone.0030233. Epub 2012 Jan 24.

18.

Identification of broad-spectrum antiviral compounds and assessment of the druggability of their target for efficacy against respiratory syncytial virus (RSV).

Bonavia A, Franti M, Pusateri Keaney E, Kuhen K, Seepersaud M, Radetich B, Shao J, Honda A, Dewhurst J, Balabanis K, Monroe J, Wolff K, Osborne C, Lanieri L, Hoffmaster K, Amin J, Markovits J, Broome M, Skuba E, Cornella-Taracido I, Joberty G, Bouwmeester T, Hamann L, Tallarico JA, Tommasi R, Compton T, Bushell SM.

Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6739-44. doi: 10.1073/pnas.1017142108. Epub 2011 Apr 18.

19.

Mutations at positions 186 and 194 in the HA gene of the 2009 H1N1 pandemic influenza virus improve replication in cell culture and eggs.

Suphaphiphat P, Franti M, Hekele A, Lilja A, Spencer T, Settembre E, Palmer G, Crotta S, Tuccino AB, Keiner B, Trusheim H, Balabanis K, Sackal M, Rothfeder M, Mandl CW, Dormitzer PR, Mason PW.

Virol J. 2010 Jul 14;7:157. doi: 10.1186/1743-422X-7-157.

20.

Human RNA polymerase I-driven reverse genetics for influenza a virus in canine cells.

Suphaphiphat P, Keiner B, Trusheim H, Crotta S, Tuccino AB, Zhang P, Dormitzer PR, Mason PW, Franti M.

J Virol. 2010 Apr;84(7):3721-5. doi: 10.1128/JVI.01925-09. Epub 2010 Jan 13.

21.

Structural and immunogenicity studies of a cleaved, stabilized envelope trimer derived from subtype A HIV-1.

Kang YK, Andjelic S, Binley JM, Crooks ET, Franti M, Iyer SP, Donovan GP, Dey AK, Zhu P, Roux KH, Durso RJ, Parsons TF, Maddon PJ, Moore JP, Olson WC.

Vaccine. 2009 Aug 13;27(37):5120-32. doi: 10.1016/j.vaccine.2009.06.037. Epub 2009 Jun 28.

22.

Relationship of HIV-1 and SIV envelope glycoprotein trimer occupation and neutralization.

Crooks ET, Jiang P, Franti M, Wong S, Zwick MB, Hoxie JA, Robinson JE, Moore PL, Binley JM.

Virology. 2008 Aug 1;377(2):364-78. doi: 10.1016/j.virol.2008.04.045. Epub 2008 Jun 9.

23.

Purified, proteolytically mature HIV type 1 SOSIP gp140 envelope trimers.

Iyer SP, Franti M, Krauchuk AA, Fisch DN, Ouattara AA, Roux KH, Krawiec L, Dey AK, Beddows S, Maddon PJ, Moore JP, Olson WC.

AIDS Res Hum Retroviruses. 2007 Jun;23(6):817-28.

PMID:
17604546
24.

A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120.

Crooks ET, Moore PL, Franti M, Cayanan CS, Zhu P, Jiang P, de Vries RP, Wiley C, Zharkikh I, Schülke N, Roux KH, Montefiori DC, Burton DR, Binley JM.

Virology. 2007 Sep 30;366(2):245-62. Epub 2007 Jun 19.

25.

A comparative immunogenicity study in rabbits of disulfide-stabilized, proteolytically cleaved, soluble trimeric human immunodeficiency virus type 1 gp140, trimeric cleavage-defective gp140 and monomeric gp120.

Beddows S, Franti M, Dey AK, Kirschner M, Iyer SP, Fisch DC, Ketas T, Yuste E, Desrosiers RC, Klasse PJ, Maddon PJ, Olson WC, Moore JP.

Virology. 2007 Apr 10;360(2):329-40. Epub 2006 Nov 28.

26.

Potent antiviral synergy between monoclonal antibody and small-molecule CCR5 inhibitors of human immunodeficiency virus type 1.

Murga JD, Franti M, Pevear DC, Maddon PJ, Olson WC.

Antimicrob Agents Chemother. 2006 Oct;50(10):3289-96.

27.

Construction and characterization of soluble, cleaved, and stabilized trimeric Env proteins based on HIV type 1 Env subtype A.

Beddows S, Kirschner M, Campbell-Gardener L, Franti M, Dey AK, Iyer SP, Maddon PJ, Paluch M, Master A, Overbaugh J, VanCott T, Olson WC, Moore JP.

AIDS Res Hum Retroviruses. 2006 Jun;22(6):569-79.

PMID:
16796532
28.

Characterizing anti-HIV monoclonal antibodies and immune sera by defining the mechanism of neutralization.

Crooks ET, Moore PL, Richman D, Robinson J, Crooks JA, Franti M, Schülke N, Binley JM.

Hum Antibodies. 2005;14(3-4):101-13.

29.

Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1.

Moore PL, Crooks ET, Porter L, Zhu P, Cayanan CS, Grise H, Corcoran P, Zwick MB, Franti M, Morris L, Roux KH, Burton DR, Binley JM.

J Virol. 2006 Mar;80(5):2515-28.

30.

Evaluating the immunogenicity of a disulfide-stabilized, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1.

Beddows S, Schülke N, Kirschner M, Barnes K, Franti M, Michael E, Ketas T, Sanders RW, Maddon PJ, Olson WC, Moore JP.

J Virol. 2005 Jul;79(14):8812-27.

31.

Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1.

Labrijn AF, Poignard P, Raja A, Zwick MB, Delgado K, Franti M, Binley J, Vivona V, Grundner C, Huang CC, Venturi M, Petropoulos CJ, Wrin T, Dimitrov DS, Robinson J, Kwong PD, Wyatt RT, Sodroski J, Burton DR.

J Virol. 2003 Oct;77(19):10557-65.

32.

Heterogeneity of envelope molecules expressed on primary human immunodeficiency virus type 1 particles as probed by the binding of neutralizing and nonneutralizing antibodies.

Poignard P, Moulard M, Golez E, Vivona V, Franti M, Venturini S, Wang M, Parren PW, Burton DR.

J Virol. 2003 Jan;77(1):353-65.

33.

Immune reactivity of human sera to the glycoprotein B of human herpesvirus 7.

Franti M, Aubin JT, De Saint-Maur G, Kosuge H, Yamanishi K, Gautheret-Dejean A, Garbarg-Chenon A, Huraux JM, Agut H.

J Clin Microbiol. 2002 Jan;40(1):44-51.

34.

Genetic polymorphism of human herpesvirus-7 among human populations.

Franti M, Gessain A, Darlu P, Gautheret-Dejean A, Kosuge H, Mauclère P, Aubin JT, Gurtsevitch V, Yamanishi K, Agut H.

J Gen Virol. 2001 Dec;82(Pt 12):3045-50.

PMID:
11714982
35.

Human herpesvirus-6 and human herpesvirus-7 in the bone marrow from healthy subjects.

Gautheret-Dejean A, Dejean O, Vastel L, Kerboull M, Aubin JT, Franti M, Agut H.

Transplantation. 2000 Apr 27;69(8):1722-3.

PMID:
10836387
36.

Preferential associations of alleles of three distinct genes argue for the existence of two prototype variants of human herpesvirus 7.

Franti M, Aubin JT, Gautheret-Dejean A, Malet I, Cahour A, Huraux JM, Agut H.

J Virol. 1999 Nov;73(11):9655-8.

37.

Definition and distribution analysis of glycoprotein B gene alleles of human herpesvirus 7.

Franti M, Aubin JT, Poirel L, Gautheret-Dejean A, Candotti D, Huraux JM, Agut H.

J Virol. 1998 Nov;72(11):8725-30.

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