Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 288

1.

Author Correction: Niche stiffness underlies the ageing of central nervous system progenitor cells.

Segel M, Neumann B, Hill MFE, Weber IP, Viscomi C, Zhao C, Young A, Agley CC, Thompson AJ, Gonzalez GA, Sharma A, Holmqvist S, Rowitch DH, Franze K, Franklin RJM, Chalut KJ.

Nature. 2019 Sep;573(7773):E3. doi: 10.1038/s41586-019-1552-1.

PMID:
31462780
2.

Niche stiffness underlies the ageing of central nervous system progenitor cells.

Segel M, Neumann B, Hill MFE, Weber IP, Viscomi C, Zhao C, Young A, Agley CC, Thompson AJ, Gonzalez GA, Sharma A, Holmqvist S, Rowitch DH, Franze K, Franklin RJM, Chalut KJ.

Nature. 2019 Sep;573(7772):130-134. doi: 10.1038/s41586-019-1484-9. Epub 2019 Aug 15. Erratum in: Nature. 2019 Aug 29;:.

PMID:
31413369
3.

Neuronal vulnerability and multilineage diversity in multiple sclerosis.

Schirmer L, Velmeshev D, Holmqvist S, Kaufmann M, Werneburg S, Jung D, Vistnes S, Stockley JH, Young A, Steindel M, Tung B, Goyal N, Bhaduri A, Mayer S, Engler JB, Bayraktar OA, Franklin RJM, Haeussler M, Reynolds R, Schafer DP, Friese MA, Shiow LR, Kriegstein AR, Rowitch DH.

Nature. 2019 Sep;573(7772):75-82. doi: 10.1038/s41586-019-1404-z. Epub 2019 Jul 17.

PMID:
31316211
4.

Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelination.

Rivera FJ, de la Fuente AG, Zhao C, Silva ME, Gonzalez GA, Wodnar R, Feichtner M, Lange S, Errea O, Priglinger E, O'Sullivan A, Romanelli P, Jadasz JJ, Brachtl G, Greil R, Tempfer H, Traweger A, Bátiz LF, Küry P, Couillard-Despres S, Franklin RJM, Aigner L.

Glia. 2019 Aug;67(8):1510-1525. doi: 10.1002/glia.23624. Epub 2019 Apr 30.

5.

Pericytes Favor Oligodendrocyte Fate Choice in Adult Neural Stem Cells.

Silva ME, Lange S, Hinrichsen B, Philp AR, Reyes CR, Halabi D, Mansilla JB, Rotheneichner P, Guzman de la Fuente A, Couillard-Despres S, Bátiz LF, Franklin RJM, Aigner L, Rivera FJ.

Front Cell Neurosci. 2019 Mar 27;13:85. doi: 10.3389/fncel.2019.00085. eCollection 2019.

6.

Diversity in the oligodendrocyte lineage: Plasticity or heterogeneity?

Foerster S, Hill MFE, Franklin RJM.

Glia. 2019 Oct;67(10):1797-1805. doi: 10.1002/glia.23607. Epub 2019 Apr 10. Review.

PMID:
30968471
7.

SUMOylation promotes survival and integration of neural stem cell grafts in ischemic stroke.

Bernstock JD, Peruzzotti-Jametti L, Leonardi T, Vicario N, Ye D, Lee YJ, Maric D, Johnson KR, Mou Y, Van Den Bosch A, Winterbone M, Friedman GK, Franklin RJM, Hallenbeck JM, Pluchino S.

EBioMedicine. 2019 Apr;42:214-224. doi: 10.1016/j.ebiom.2019.03.035. Epub 2019 Mar 21.

8.

Transforming growth factor-beta renders ageing microglia inhibitory to oligodendrocyte generation by CNS progenitors.

Baror R, Neumann B, Segel M, Chalut KJ, Fancy SPJ, Schafer DP, Franklin RJM.

Glia. 2019 Jul;67(7):1374-1384. doi: 10.1002/glia.23612. Epub 2019 Mar 12.

9.

Toxin-Based Models to Investigate Demyelination and Remyelination.

McMurran CE, Zhao C, Franklin RJM.

Methods Mol Biol. 2019;1936:377-396. doi: 10.1007/978-1-4939-9072-6_21.

PMID:
30820910
10.

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes.

Hammond TR, Dufort C, Dissing-Olesen L, Giera S, Young A, Wysoker A, Walker AJ, Gergits F, Segel M, Nemesh J, Marsh SE, Saunders A, Macosko E, Ginhoux F, Chen J, Franklin RJM, Piao X, McCarroll SA, Stevens B.

Immunity. 2019 Jan 15;50(1):253-271.e6. doi: 10.1016/j.immuni.2018.11.004. Epub 2018 Nov 21.

PMID:
30471926
11.

A Subpopulation of Foxj1-Expressing, Nonmyelinating Schwann Cells of the Peripheral Nervous System Contribute to Schwann Cell Remyelination in the Central Nervous System.

Ma D, Wang B, Zawadzka M, Gonzalez G, Wu Z, Yu B, Rawlins EL, Franklin RJM, Zhao C.

J Neurosci. 2018 Oct 24;38(43):9228-9239. doi: 10.1523/JNEUROSCI.0585-18.2018. Epub 2018 Sep 18.

12.

Injury-induced perivascular niche supports alternative differentiation of adult rodent CNS progenitor cells.

Ulanska-Poutanen J, Mieczkowski J, Zhao C, Konarzewska K, Kaza B, Pohl HB, Bugajski L, Kaminska B, Franklin RJ, Zawadzka M.

Elife. 2018 Sep 17;7. pii: e30325. doi: 10.7554/eLife.30325.

13.

Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity.

Schirmer L, Möbius W, Zhao C, Cruz-Herranz A, Ben Haim L, Cordano C, Shiow LR, Kelley KW, Sadowski B, Timmons G, Pröbstel AK, Wright JN, Sin JH, Devereux M, Morrison DE, Chang SM, Sabeur K, Green AJ, Nave KA, Franklin RJ, Rowitch DH.

Elife. 2018 Sep 11;7. pii: e36428. doi: 10.7554/eLife.36428.

14.

Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo.

Reuberson J, Horsley H, Franklin RJ, Ford D, Neuss J, Brookings D, Huang Q, Vanderhoydonck B, Gao LJ, Jang MY, Herdewijn P, Ghawalkar A, Fallah-Arani F, Khan AR, Henshall J, Jairaj M, Malcolm S, Ward E, Shuttleworth L, Lin Y, Li S, Louat T, Waer M, Herman J, Payne A, Ceska T, Doyle C, Pitt W, Calmiano M, Augustin M, Steinbacher S, Lammens A, Allen R.

J Med Chem. 2018 Aug 9;61(15):6705-6723. doi: 10.1021/acs.jmedchem.8b00521. Epub 2018 Jul 19.

PMID:
29952567
15.

Clinical implications of myelin regeneration in the central nervous system.

McMurran CE, Kodali S, Young A, Franklin RJ.

Expert Rev Neurother. 2018 Feb;18(2):111-123. doi: 10.1080/14737175.2018.1421458. Epub 2018 Jan 3. Review.

PMID:
29285954
16.

Clemastine rescues myelination defects and promotes functional recovery in hypoxic brain injury.

Cree BAC, Niu J, Hoi KK, Zhao C, Caganap SD, Henry RG, Dao DQ, Zollinger DR, Mei F, Shen YA, Franklin RJM, Ullian EM, Xiao L, Chan JR, Fancy SPJ.

Brain. 2018 Jan 1;141(1):85-98. doi: 10.1093/brain/awx312.

17.

Regenerating CNS myelin - from mechanisms to experimental medicines.

Franklin RJM, Ffrench-Constant C.

Nat Rev Neurosci. 2017 Nov 16;18(12):753-769. doi: 10.1038/nrn.2017.136. Review.

PMID:
29142295
18.

Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination.

De La Fuente AG, Lange S, Silva ME, Gonzalez GA, Tempfer H, van Wijngaarden P, Zhao C, Di Canio L, Trost A, Bieler L, Zaunmair P, Rotheneichner P, O'Sullivan A, Couillard-Despres S, Errea O, Mäe MA, Andrae J, He L, Keller A, Bátiz LF, Betsholtz C, Aigner L, Franklin RJM, Rivera FJ.

Cell Rep. 2017 Aug 22;20(8):1755-1764. doi: 10.1016/j.celrep.2017.08.007.

19.

LncRNA GAS5 inhibits microglial M2 polarization and exacerbates demyelination.

Sun D, Yu Z, Fang X, Liu M, Pu Y, Shao Q, Wang D, Zhao X, Huang A, Xiang Z, Zhao C, Franklin RJ, Cao L, He C.

EMBO Rep. 2017 Oct;18(10):1801-1816. doi: 10.15252/embr.201643668. Epub 2017 Aug 14.

20.

Do Not Adjust Your Mind: The Fault Is in Your Glia.

Franklin RJM, Bullmore ET.

Cell Stem Cell. 2017 Aug 3;21(2):155-156. doi: 10.1016/j.stem.2017.07.005.

21.

Recruitment of endogenous CNS stem cells for regeneration in demyelinating disease.

Murphy NA, Franklin RJM.

Prog Brain Res. 2017;231:135-163. doi: 10.1016/bs.pbr.2016.12.013. Epub 2017 Feb 23. Review.

PMID:
28554395
22.

Erratum to: Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination.

Syed YA, Zhao C, Mahad D, Möbius W, Altmann F, Foss F, González GA, Sentürk A, Acker-Palmer A, Lubec G, Lilley K, Franklin RJM, Nave KA, Kotter MRN.

Acta Neuropathol. 2017 Jul;134(1):167-168. doi: 10.1007/s00401-017-1712-z. No abstract available.

PMID:
28484846
23.

Mechanical Strain Promotes Oligodendrocyte Differentiation by Global Changes of Gene Expression.

Jagielska A, Lowe AL, Makhija E, Wroblewska L, Guck J, Franklin RJM, Shivashankar GV, Van Vliet KJ.

Front Cell Neurosci. 2017 Apr 20;11:93. doi: 10.3389/fncel.2017.00093. eCollection 2017.

24.

Efficient Remyelination Requires DNA Methylation.

Moyon S, Ma D, Huynh JL, Coutts DJC, Zhao C, Casaccia P, Franklin RJM.

eNeuro. 2017 Mar 30;4(2). pii: ENEURO.0336-16.2017. doi: 10.1523/ENEURO.0336-16.2017. eCollection 2017 Mar-Apr.

25.

Regulatory T cells promote myelin regeneration in the central nervous system.

Dombrowski Y, O'Hagan T, Dittmer M, Penalva R, Mayoral SR, Bankhead P, Fleville S, Eleftheriadis G, Zhao C, Naughton M, Hassan R, Moffat J, Falconer J, Boyd A, Hamilton P, Allen IV, Kissenpfennig A, Moynagh PN, Evergren E, Perbal B, Williams AC, Ingram RJ, Chan JR, Franklin RJM, Fitzgerald DC.

Nat Neurosci. 2017 May;20(5):674-680. doi: 10.1038/nn.4528. Epub 2017 Mar 13.

26.

Subependymal Zone-Derived Oligodendroblasts Respond to Focal Demyelination but Fail to Generate Myelin in Young and Aged Mice.

Kazanis I, Evans KA, Andreopoulou E, Dimitriou C, Koutsakis C, Karadottir RT, Franklin RJM.

Stem Cell Reports. 2017 Mar 14;8(3):685-700. doi: 10.1016/j.stemcr.2017.01.007. Epub 2017 Feb 9.

27.

Unexpected central role of the androgen receptor in the spontaneous regeneration of myelin.

Bielecki B, Mattern C, Ghoumari AM, Javaid S, Smietanka K, Abi Ghanem C, Mhaouty-Kodja S, Ghandour MS, Baulieu EE, Franklin RJ, Schumacher M, Traiffort E.

Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14829-14834. doi: 10.1073/pnas.1614826113. Epub 2016 Dec 7.

28.

MRI measurements of reporter-mediated increases in transmembrane water exchange enable detection of a gene reporter.

Schilling F, Ros S, Hu DE, D'Santos P, McGuire S, Mair R, Wright AJ, Mannion E, Franklin RJ, Neves AA, Brindle KM.

Nat Biotechnol. 2017 Jan;35(1):75-80. doi: 10.1038/nbt.3714. Epub 2016 Dec 5.

29.

Electric Signals Regulate the Directional Migration of Oligodendrocyte Progenitor Cells (OPCs) via β1 Integrin.

Zhu B, Nicholls M, Gu Y, Zhang G, Zhao C, Franklin RJ, Song B.

Int J Mol Sci. 2016 Nov 22;17(11). pii: E1948.

30.

Axonal plasticity underpins the functional recovery following surgical decompression in a rat model of cervical spondylotic myelopathy.

Dhillon RS, Parker J, Syed YA, Edgley S, Young A, Fawcett JW, Jeffery ND, Franklin RJ, Kotter MR.

Acta Neuropathol Commun. 2016 Aug 23;4(1):89. doi: 10.1186/s40478-016-0359-7.

31.

CNS Remyelination and the Innate Immune System.

McMurran CE, Jones CA, Fitzgerald DC, Franklin RJ.

Front Cell Dev Biol. 2016 May 3;4:38. doi: 10.3389/fcell.2016.00038. eCollection 2016. Review.

32.

Erratum to: Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination.

Syed YA, Zhao C, Mahad D, Möbius W, Altmann F, Foss F, González GA, Sentürk A, Acker-Palmer A, Lubec G, Lilley K, Franklin RJ, Nave KA, Kotter MR.

Acta Neuropathol. 2016 Jul;132(1):157. No abstract available.

33.

Developmental Origin of Oligodendrocyte Lineage Cells Determines Response to Demyelination and Susceptibility to Age-Associated Functional Decline.

Crawford AH, Tripathi RB, Richardson WD, Franklin RJM.

Cell Rep. 2016 Apr 26;15(4):761-773. doi: 10.1016/j.celrep.2016.03.069. Epub 2016 Apr 14.

34.

Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage.

Moyon S, Huynh JL, Dutta D, Zhang F, Ma D, Yoo S, Lawrence R, Wegner M, John GR, Emery B, Lubetzki C, Franklin RJM, Fan G, Zhu J, Dupree JL, Casaccia P.

Cell Rep. 2016 Apr 26;15(4):748-760. doi: 10.1016/j.celrep.2016.03.060. Epub 2016 Apr 14.

35.

Pre-Existing Mature Oligodendrocytes Do Not Contribute to Remyelination following Toxin-Induced Spinal Cord Demyelination.

Crawford AH, Tripathi RB, Foerster S, McKenzie I, Kougioumtzidou E, Grist M, Richardson WD, Franklin RJ.

Am J Pathol. 2016 Mar;186(3):511-6. doi: 10.1016/j.ajpath.2015.11.005. Epub 2016 Jan 7.

36.

Pioglitazone regulates myelin phagocytosis and multiple sclerosis monocytes.

Natrajan MS, Komori M, Kosa P, Johnson KR, Wu T, Franklin RJ, Bielekova B.

Ann Clin Transl Neurol. 2015 Oct 27;2(12):1071-84. doi: 10.1002/acn3.260. eCollection 2015 Dec.

37.

Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination.

Syed YA, Zhao C, Mahad D, Möbius W, Altmann F, Foss F, González GA, Sentürk A, Acker-Palmer A, Lubec G, Lilley K, Franklin RJM, Nave KA, Kotter MRN.

Acta Neuropathol. 2016 Feb;131(2):281-298. doi: 10.1007/s00401-015-1521-1. Epub 2015 Dec 19. Erratum in: Acta Neuropathol. 2016 Jul;132(1):157. Acta Neuropathol. 2017 Jul;134(1):167-168.

38.

Vitamin D receptor-retinoid X receptor heterodimer signaling regulates oligodendrocyte progenitor cell differentiation.

de la Fuente AG, Errea O, van Wijngaarden P, Gonzalez GA, Kerninon C, Jarjour AA, Lewis HJ, Jones CA, Nait-Oumesmar B, Zhao C, Huang JK, ffrench-Constant C, Franklin RJ.

J Cell Biol. 2015 Dec 7;211(5):975-85. doi: 10.1083/jcb.201505119.

39.

Neuronal expression of pathological tau accelerates oligodendrocyte progenitor cell differentiation.

Ossola B, Zhao C, Compston A, Pluchino S, Franklin RJ, Spillantini MG.

Glia. 2016 Mar;64(3):457-71. doi: 10.1002/glia.22940. Epub 2015 Nov 18.

40.

Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination.

Natrajan MS, de la Fuente AG, Crawford AH, Linehan E, Nuñez V, Johnson KR, Wu T, Fitzgerald DC, Ricote M, Bielekova B, Franklin RJ.

Brain. 2015 Dec;138(Pt 12):3581-97. doi: 10.1093/brain/awv289. Epub 2015 Oct 12.

41.

Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors.

Gautier HO, Evans KA, Volbracht K, James R, Sitnikov S, Lundgaard I, James F, Lao-Peregrin C, Reynolds R, Franklin RJ, Káradóttir RT.

Nat Commun. 2015 Oct 6;6:8518. doi: 10.1038/ncomms9518.

42.

Discovery of a novel neuroprotectant, BHDPC, that protects against MPP+/MPTP-induced neuronal death in multiple experimental models.

Chong CM, Ma D, Zhao C, Franklin RJ, Zhou ZY, Ai N, Li C, Yu H, Hou T, Sa F, Lee SM.

Free Radic Biol Med. 2015 Dec;89:1057-66. doi: 10.1016/j.freeradbiomed.2015.08.013. Epub 2015 Sep 28.

PMID:
26415025
43.

Sox2 Sustains Recruitment of Oligodendrocyte Progenitor Cells following CNS Demyelination and Primes Them for Differentiation during Remyelination.

Zhao C, Ma D, Zawadzka M, Fancy SP, Elis-Williams L, Bouvier G, Stockley JH, de Castro GM, Wang B, Jacobs S, Casaccia P, Franklin RJ.

J Neurosci. 2015 Aug 19;35(33):11482-99. doi: 10.1523/JNEUROSCI.3655-14.2015. Erratum in: J Neurosci. 2017 Sep 20;37(38):9345.

44.

Astrocyte Activation via Stat3 Signaling Determines the Balance of Oligodendrocyte versus Schwann Cell Remyelination.

Monteiro de Castro G, Deja NA, Ma D, Zhao C, Franklin RJ.

Am J Pathol. 2015 Sep;185(9):2431-40. doi: 10.1016/j.ajpath.2015.05.011. Epub 2015 Jul 17.

45.

Regenerative Medicines for Remyelination: From Aspiration to Reality.

Franklin RJ.

Cell Stem Cell. 2015 Jun 4;16(6):576-7. doi: 10.1016/j.stem.2015.05.010.

46.

Glia Disease and Repair-Remyelination.

Franklin RJ, Goldman SA.

Cold Spring Harb Perspect Biol. 2015 May 18;7(7):a020594. doi: 10.1101/cshperspect.a020594. Review.

47.

Fibroblast growth factor signaling in oligodendrocyte-lineage cells facilitates recovery of chronically demyelinated lesions but is redundant in acute lesions.

Furusho M, Roulois AJ, Franklin RJ, Bansal R.

Glia. 2015 Oct;63(10):1714-28. doi: 10.1002/glia.22838. Epub 2015 Apr 22.

48.

The Complement Receptor C5aR Controls Acute Inflammation and Astrogliosis following Spinal Cord Injury.

Brennan FH, Gordon R, Lao HW, Biggins PJ, Taylor SM, Franklin RJ, Woodruff TM, Ruitenberg MJ.

J Neurosci. 2015 Apr 22;35(16):6517-31. doi: 10.1523/JNEUROSCI.5218-14.2015.

49.

Lesion-induced accumulation of platelets promotes survival of adult neural stem / progenitor cells.

Kazanis I, Feichtner M, Lange S, Rotheneichner P, Hainzl S, Öller M, Schallmoser K, Rohde E, Reitsamer HA, Couillard-Despres S, Bauer HC, Franklin RJ, Aigner L, Rivera FJ.

Exp Neurol. 2015 Jul;269:75-89. doi: 10.1016/j.expneurol.2015.03.018. Epub 2015 Mar 24.

PMID:
25819103
50.

Demyelination causes adult CNS progenitors to revert to an immature state and express immune cues that support their migration.

Moyon S, Dubessy AL, Aigrot MS, Trotter M, Huang JK, Dauphinot L, Potier MC, Kerninon C, Melik Parsadaniantz S, Franklin RJ, Lubetzki C.

J Neurosci. 2015 Jan 7;35(1):4-20. doi: 10.1523/JNEUROSCI.0849-14.2015.

Supplemental Content

Loading ...
Support Center