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Items: 1 to 50 of 128

1.

Traditional Preparations and Methanol Extracts of Medicinal Plants from Papua New Guinea Exhibit Similar Cytochrome P450 Inhibition.

Larson EC, Pond CD, Rai PP, Matainaho TK, Piskaut P, Franklin MR, Barrows LR.

Evid Based Complement Alternat Med. 2016;2016:7869710. doi: 10.1155/2016/7869710. Epub 2016 Aug 24.

2.

A method for determining δ-aminolevulinic acid synthase activity in homogenized cells and tissues.

Bergonia HA, Franklin MR, Kushner JP, Phillips JD.

Clin Biochem. 2015 Aug;48(12):788-95. doi: 10.1016/j.clinbiochem.2015.04.023. Epub 2015 May 8.

3.

Interactions of Papua New Guinea medicinal plant extracts with antiretroviral therapy.

Larson EC, Hathaway LB, Lamb JG, Pond CD, Rai PP, Matainaho TK, Piskaut P, Barrows LR, Franklin MR.

J Ethnopharmacol. 2014 Sep 29;155(3):1433-40. doi: 10.1016/j.jep.2014.07.023. Epub 2014 Aug 17.

4.

Obituary for professor Garold S. Yost (1948-2014).

Bolton JL, Reilly CA, Franklin MR.

Chem Res Toxicol. 2014 Aug 18;27(8):1327. doi: 10.1021/tx500301c. Epub 2014 Jul 28. No abstract available.

PMID:
25068804
5.

Comparative analysis of human CYP3A4 and rat CYP3A1 induction and relevant gene expression by bisphenol A and diethylstilbestrol: implications for toxicity testing paradigms.

Kuzbari O, Peterson CM, Franklin MR, Hathaway LB, Johnstone EB, Hammoud AO, Lamb JG.

Reprod Toxicol. 2013 Jun;37:24-30. doi: 10.1016/j.reprotox.2013.01.005. Epub 2013 Feb 4.

PMID:
23384967
6.

Major differences among chemopreventive organoselenocompounds in the sustained elevation of cytoprotective genes.

Poerschke RL, Franklin MR, Bild AH, Moos PJ.

J Biochem Mol Toxicol. 2012 Sep;26(9):344-53. doi: 10.1002/jbt.21427. Epub 2012 Jul 16.

7.

A once-per-day, drug-in-food protocol for prolonged administration of antiepileptic drugs in animal models.

Ali A, Dua Y, Constance JE, Franklin MR, Dudek FE.

Epilepsia. 2012 Jan;53(1):199-206. doi: 10.1111/j.1528-1167.2011.03314.x. Epub 2011 Nov 16.

8.

Identifying and overcoming the constraints that prevent the full implementation of decommissioning and remediation programs in uranium mining sites.

Franklin MR, Fernandes HM.

J Environ Radioact. 2013 May;119:48-54. doi: 10.1016/j.jenvrad.2011.08.018. Epub 2011 Sep 28.

PMID:
21955840
9.

Uroporphyria in the Cyp1a2-/- mouse.

Phillips JD, Kushner JP, Bergonia HA, Franklin MR.

Blood Cells Mol Dis. 2011 Dec 15;47(4):249-54. doi: 10.1016/j.bcmd.2011.07.006. Epub 2011 Aug 30.

10.

Nanosilver particle effects on drug metabolism in vitro.

Lamb JG, Hathaway LB, Munger MA, Raucy JL, Franklin MR.

Drug Metab Dispos. 2010 Dec;38(12):2246-51. doi: 10.1124/dmd.110.035238. Epub 2010 Sep 22.

PMID:
20861156
11.

Hyper- and hypo-induction of cytochrome P450 activities with Aroclor 1254 and 3-methylcholanthrene in Cyp1a2(-/-) mice.

Barker ML, Hathaway LB, Arch DD, Westbroek ML, Kushner JP, Phillips JD, Franklin MR.

Chem Biol Interact. 2009 Dec 10;182(2-3):220-6. doi: 10.1016/j.cbi.2009.09.007. Epub 2009 Sep 20.

12.

Longitudinal study of a mouse model of familial porphyria cutanea tarda.

Arch DD, Bergeron M, Hathaway L, Kushner JP, Phillips JD, Franklin MR.

Cell Mol Biol (Noisy-le-grand). 2009 Jul 1;55(2):46-54.

PMID:
19656451
13.
14.

Modulation of redox status in human lung cell lines by organoselenocompounds: selenazolidines, selenomethionine, and methylseleninic acid.

Poerschke RL, Franklin MR, Moos PJ.

Toxicol In Vitro. 2008 Oct;22(7):1761-7. doi: 10.1016/j.tiv.2008.08.003. Epub 2008 Aug 15.

15.

"Pharm-ecology" of diet shifting: biotransformation of plant secondary compounds in creosote (Larrea tridentata) by a woodrat herbivore, Neotoma lepida.

Haley SL, Lamb JG, Franklin MR, Constance JE, Dearing MD.

Physiol Biochem Zool. 2008 Sep-Oct;81(5):584-93. doi: 10.1086/589951.

PMID:
18752424
16.

The anticonvulsant profile of rufinamide (CGP 33101) in rodent seizure models.

White HS, Franklin MR, Kupferberg HJ, Schmutz M, Stables JP, Wolf HH.

Epilepsia. 2008 Jul;49(7):1213-20. doi: 10.1111/j.1528-1167.2008.01552.x.

17.

Xenobiotic metabolism of plant secondary compounds in oak (Quercus agrifolia) by specialist and generalist woodrat herbivores, genus Neotoma.

Haley SL, Lamb JG, Franklin MR, Constance JE, Dearing MD.

J Chem Ecol. 2007 Nov;33(11):2111-22. Epub 2007 Oct 11.

PMID:
17929091
18.
19.

Xenobiotic metabolism of plant secondary compounds in juniper (Juniperus monosperma) by specialist and generalist woodrat herbivores, genus Neotoma.

Haley SL, Lamb JG, Franklin MR, Constance JE, Denise Dearing M.

Comp Biochem Physiol C Toxicol Pharmacol. 2007 Nov;146(4):552-60. Epub 2007 Jun 30.

PMID:
17681888
20.

Critical analysis of the waste management performance of two uranium production units in Brazil--part II: Caetite production center.

Fernandes HM, Gomiero LA, Peres V, Franklin MR, Simões Filho FF.

J Environ Manage. 2008 Sep;88(4):914-25. Epub 2007 Jul 9.

PMID:
17619076
21.

Critical analysis of the waste management performance of two uranium production units in Brazil--part I: Poços de Caldas production centre.

Fernandes HM, Franklin MR, Gomiero LA.

J Environ Manage. 2008 Apr;87(1):59-72. Epub 2007 Jun 12.

PMID:
17566635
22.
23.

A porphomethene inhibitor of uroporphyrinogen decarboxylase causes porphyria cutanea tarda.

Phillips JD, Bergonia HA, Reilly CA, Franklin MR, Kushner JP.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5079-84. Epub 2007 Mar 9.

24.

The antimutagenicity of 2-substituted selenazolidine-4-(R)-carboxylic acids.

El-Sayed WM, Hussin WA, Franklin MR.

Mutat Res. 2007 Mar 5;627(2):136-45. Epub 2006 Dec 12.

25.

Hepatic chemoprotective enzyme responses to 2-substituted selenazolidine-4(R)-carboxylic acids.

El-Sayed WM, Franklin MR.

J Biochem Mol Toxicol. 2006;20(6):292-301.

PMID:
17163488
26.

Murine hepatoma (Hepa1c1c7) cells: a responsive in vitro system for chemoprotective enzyme induction by organoselenium compounds.

El-Sayed WM, Aboul-Fadl T, Roberts JC, Lamb JG, Franklin MR.

Toxicol In Vitro. 2007 Feb;21(1):157-64. Epub 2006 Oct 7.

27.

Acute effects of novel selenazolidines on murine chemoprotective enzymes.

El-Sayed WM, Aboul-Fadl T, Lamb JG, Roberts JC, Franklin MR.

Chem Biol Interact. 2006 Jul 25;162(1):31-42. doi: 10.1016/j.cbi.2006.05.002.

PMID:
16765927
28.

Radioecological characterization of a uranium mining site located in a semi-arid region in Brazil.

Fernandes HM, Lamego Simoes Filho FF, Perez V, Franklin MR, Gomiero LA.

J Environ Radioact. 2006;88(2):140-57. Epub 2006 Mar 20.

PMID:
16545512
29.

Effect of selenium-containing compounds on hepatic chemoprotective enzymes in mice.

El-Sayed WM, Aboul-Fadl T, Lamb JG, Roberts JC, Franklin MR.

Toxicology. 2006 Mar 15;220(2-3):179-88. Epub 2006 Jan 31.

PMID:
16451816
30.

Chemopreventive activity of selenocysteine prodrugs against tobacco-derived nitrosamine (NNK) induced lung tumors in the A/J mouse.

Li L, Xie Y, El-Sayed WM, Szakacs JG, Franklin MR, Roberts JC.

J Biochem Mol Toxicol. 2005;19(6):396-405.

PMID:
16421895
31.

Attenuation of polychlorinated biphenyl induced uroporphyria by iron deprivation.

Franklin MR, Phillips JD, Kushner JP.

Environ Toxicol Pharmacol. 2005 Nov;20(3):417-23. doi: 10.1016/j.etap.2005.05.001. Epub 2005 Jul 5.

PMID:
21783621
32.
33.

Modulation of phase II drug metabolizing enzyme activities by N-heterocycles.

Franklin MR.

Curr Drug Metab. 2002 Dec;3(6):599-607. Review.

PMID:
12369888
34.
35.
36.

Accelerated development of uroporphyria in mice heterozygous for a deletion at the uroporphyrinogen decarboxylase locus.

Franklin MR, Phillips JD, Kushner JP.

J Biochem Mol Toxicol. 2001;15(5):287-93.

PMID:
11835626
37.

The influence of L-glutamine on the depression of hepatic cytochrome P450 activity in male rats caused by total parenteral nutrition.

Shaw AA, Hall SD, Franklin MR, Galinsky RE.

Drug Metab Dispos. 2002 Feb;30(2):177-82.

PMID:
11792688
38.
39.

The psoralens adversely affect reproductive function in male wistar rats.

Diawaraa MM, Chavez KJ, Simpleman D, Williams DE, Franklin MR, Hoyer PB.

Reprod Toxicol. 2001 Mar-Apr;15(2):137-44.

PMID:
11297873
40.

A mouse model of familial porphyria cutanea tarda.

Phillips JD, Jackson LK, Bunting M, Franklin MR, Thomas KR, Levy JE, Andrews NC, Kushner JP.

Proc Natl Acad Sci U S A. 2001 Jan 2;98(1):259-64.

41.

Transdermal estrogen replacement therapy in postmenopausal women previously treated for porphyria cutanea tarda.

Bulaj ZJ, Franklin MR, Phillips JD, Miller KL, Bergonia HA, Ajioka RS, Griffen LM, Guinee DJ, Edwards CQ, Kushner JP.

J Lab Clin Med. 2000 Dec;136(6):482-8.

PMID:
11128750
42.

CYP3A-inducing agents and the attenuation of uroporphyrin accumulation and excretion in a rat model of porphyria cutanea tarda.

Franklin MR, Phillips JD, Kushner JP.

Biochem Pharmacol. 2000 Nov 1;60(9):1325-31.

PMID:
11008126
44.

Hemochromatosis genes and other factors contributing to the pathogenesis of porphyria cutanea tarda.

Bulaj ZJ, Phillips JD, Ajioka RS, Franklin MR, Griffen LM, Guinee DJ, Edwards CQ, Kushner JP.

Blood. 2000 Mar 1;95(5):1565-71.

PMID:
10688809
45.

A novel group of ovarian toxicants: the psoralens.

Diawara MM, Chavez KJ, Hoyer PB, Williams DE, Dorsch J, Kulkosky P, Franklin MR.

J Biochem Mol Toxicol. 1999;13(3-4):195-203.

PMID:
10098905
46.
47.
48.

Differential chemoprotection against acetaminophen-induced hepatotoxicity by latentiated L-cysteines.

Roberts JC, Phaneuf HL, Szakacs JG, Zera RT, Lamb JG, Franklin MR.

Chem Res Toxicol. 1998 Nov;11(11):1274-82.

PMID:
9815187

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