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Items: 1 to 50 of 396

1.

PRAS: Predicting functional targets of RNA binding proteins based on CLIP-seq peaks.

Lin J, Zhang Y, Frankel WN, Ouyang Z.

PLoS Comput Biol. 2019 Aug 19;15(8):e1007227. doi: 10.1371/journal.pcbi.1007227. [Epub ahead of print]

2.

Multinucleated stromal giant cells in the gastroesophageal junctional and gastric mucosa: a retrospective study.

Sachak T, Frankel WL, Arnold CA, Chen W.

Diagn Pathol. 2019 Jul 27;14(1):83. doi: 10.1186/s13000-019-0860-y.

3.

"Histology of colorectal adenocarcinoma with double somatic mismatch-repair mutations is indistinguishable from those caused by Lynch syndrome"-reply.

Pearlman R, Hemminger J, Hampel H, Frankel WL.

Hum Pathol. 2019 Jul;89:116-117. doi: 10.1016/j.humpath.2019.04.017. Epub 2019 May 7. No abstract available.

PMID:
31075301
4.

Evaluation of the volume-value relationship in hip fracture care using evidence-based thresholds.

Navarro SM, Frankel WC, Haeberle HS, Billow DG, Ramkumar PN.

Hip Int. 2019 Mar 26:1120700019837130. doi: 10.1177/1120700019837130. [Epub ahead of print]

PMID:
30912450
5.

Clinical characteristics of patients with colorectal cancer with double somatic mismatch repair mutations compared with Lynch syndrome.

Pearlman R, Haraldsdottir S, de la Chapelle A, Jonasson JG, Liyanarachchi S, Frankel WL, Rafnar T, Stefansson K, Pritchard CC, Hampel H.

J Med Genet. 2019 Jul;56(7):462-470. doi: 10.1136/jmedgenet-2018-105698. Epub 2019 Mar 15.

PMID:
30877237
6.

Microsatellite Instability Occurs in a Subset of Follicular Thyroid Cancers.

Genutis LK, Tomsic J, Bundschuh RA, Brock PL, Williams MD, Roychowdhury S, Reeser JW, Frankel WL, Alsomali M, Routbort MJ, Broaddus RR, Wakely PE Jr, Phay JE, Walker CJ, de la Chapelle A.

Thyroid. 2019 Apr;29(4):523-529. doi: 10.1089/thy.2018.0655. Epub 2019 Mar 27.

PMID:
30747051
7.

A practical guide to biomarkers for the evaluation of colorectal cancer.

Chen W, Frankel WL.

Mod Pathol. 2019 Jan 2. doi: 10.1038/s41379-018-0136-1. [Epub ahead of print] Review.

PMID:
30600322
8.

Patients at Risk for Aortic Rupture Often Exposed to Fluoroquinolones during Hospitalization.

Frankel WC, Trautner BW, Spiegelman A, Grigoryan L, LeMaire SA.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01712-18. doi: 10.1128/AAC.01712-18. Print 2019 Feb.

9.

Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth.

Pitarresi JR, Liu X, Avendano A, Thies KA, Sizemore GM, Hammer AM, Hildreth BE 3rd, Wang DJ, Steck SA, Donohue S, Cuitiño MC, Kladney RD, Mace TA, Chang JJ, Ennis CS, Li H, Reeves RH, Blackshaw S, Zhang J, Yu L, Fernandez SA, Frankel WL, Bloomston M, Rosol TJ, Lesinski GB, Konieczny SF, Guttridge DC, Rustgi AK, Leone G, Song JW, Wu J, Ostrowski MC.

Life Sci Alliance. 2018 Oct 26;1(5):e201800190. doi: 10.26508/lsa.201800190. eCollection 2018 Oct.

10.

miR-224 Is Significantly Upregulated and Targets Caspase-3 and Caspase-7 During Colorectal Carcinogenesis.

Fassan M, Cui R, Gasparini P, Mescoli C, Guzzardo V, Vicentini C, Munari G, Loupakis F, Lonardi S, Braconi C, Scarpa M, D'Angelo E, Pucciarelli S, Angriman I, Agostini M, D'Incá R, Farinati F, Gafà R, Lanza G, Frankel WL, Croce CM, Valeri N, Rugge M.

Transl Oncol. 2019 Feb;12(2):282-291. doi: 10.1016/j.tranon.2018.10.013. Epub 2018 Nov 16.

11.

Optimizing the Volume-Value Relationship in Laminectomy: An Evidence-Based Analysis of Outcomes and Economies of Scale.

Frankel WC, Navarro SM, Haeberle HS, Ramanathan D, Ramkumar PN.

Spine (Phila Pa 1976). 2019 May 1;44(9):659-669. doi: 10.1097/BRS.0000000000002910.

PMID:
30363014
12.

The Evidence Behind Peroxide in Orthopedic Surgery.

Navarro SM, Haeberle HS, Sokunbi OF, Frankel WC, Wera GD, Mont MA, Ramkumar PN.

Orthopedics. 2018 Nov 1;41(6):e756-e764. doi: 10.3928/01477447-20181010-07. Epub 2018 Oct 16.

PMID:
30321442
13.

meaRtools: An R package for the analysis of neuronal networks recorded on microelectrode arrays.

Gelfman S, Wang Q, Lu YF, Hall D, Bostick CD, Dhindsa R, Halvorsen M, McSweeney KM, Cotterill E, Edinburgh T, Beaumont MA, Frankel WN, Petrovski S, Allen AS, Boland MJ, Goldstein DB, Eglen SJ.

PLoS Comput Biol. 2018 Oct 1;14(10):e1006506. doi: 10.1371/journal.pcbi.1006506. eCollection 2018 Oct.

14.

Fixed and Variable Relationship Models to Define the Volume-Value Relationship in Spinal Fusion Surgery: A Macroeconomic Analysis Using Evidence-Based Thresholds.

Navarro SM, Frankel WC, Haeberle HS, Ramkumar PN.

Neurospine. 2018 Sep;15(3):249-260. doi: 10.14245/ns.1836088.044. Epub 2018 Sep 6.

15.

MicroRNA molecular profiling identifies potential signaling pathways conferring resistance to chemoradiation in locally-advanced rectal adenocarcinoma.

Pettit C, Webb A, Walston S, Chatterjee M, Chen W, Frankel W, Croce C, Williams TM.

Oncotarget. 2018 Jun 22;9(48):28951-28964. doi: 10.18632/oncotarget.25652. eCollection 2018 Jun 22.

16.

Two-stain immunohistochemical screening for Lynch syndrome in colorectal cancer may fail to detect mismatch repair deficiency.

Pearlman R, Markow M, Knight D, Chen W, Arnold CA, Pritchard CC, Hampel H, Frankel WL.

Mod Pathol. 2018 Dec;31(12):1891-1900. doi: 10.1038/s41379-018-0058-y. Epub 2018 Jul 2.

PMID:
29967423
17.

Corrigendum to 'Evidence-Based Thresholds for the Volume and Length of Stay Relationship in Total Hip Arthroplasty: Outcomes and Economies of Scale' [Journal of Arthroplasty 33 (2018) 2031-2037].

Ramkumar PN, Navarro SM, Frankel WC, Haeberle HS, Delanois RE, Mont MA.

J Arthroplasty. 2018 Sep;33(9):3060-3061. doi: 10.1016/j.arth.2018.06.011. Epub 2018 Jun 28. No abstract available.

PMID:
29960826
18.

Crystal-storing Histiocytosis in the Stomach: A Clue to Subtle Hematolymphoid Malignancies.

Arnold CA, Frankel WL, Guo L, Krishnan C, Pfeil S, Schumacher M, Voltaggio L, Yearsley MM, Chen W.

Am J Surg Pathol. 2018 Oct;42(10):1317-1324. doi: 10.1097/PAS.0000000000001097.

PMID:
29878935
19.

Histology of colorectal adenocarcinoma with double somatic mismatch-repair mutations is indistinguishable from those caused by Lynch syndrome.

Hemminger JA, Pearlman R, Haraldsdottir S, Knight D, Jonasson JG, Pritchard CC, Hampel H, Frankel WL.

Hum Pathol. 2018 Aug;78:125-130. doi: 10.1016/j.humpath.2018.04.017. Epub 2018 May 1.

20.

Evidence-Based Thresholds for the Volume and Cost Relationship in Total Hip Arthroplasty: Outcomes and Economies of Scale.

Haeberle HS, Navarro SM, Frankel WC, Mont MA, Ramkumar PN.

J Arthroplasty. 2018 Aug;33(8):2398-2404. doi: 10.1016/j.arth.2018.02.093. Epub 2018 Mar 15.

PMID:
29666028
21.

Assessment of Tumor Sequencing as a Replacement for Lynch Syndrome Screening and Current Molecular Tests for Patients With Colorectal Cancer.

Hampel H, Pearlman R, Beightol M, Zhao W, Jones D, Frankel WL, Goodfellow PJ, Yilmaz A, Miller K, Bacher J, Jacobson A, Paskett E, Shields PG, Goldberg RM, de la Chapelle A, Shirts BH, Pritchard CC; Ohio Colorectal Cancer Prevention Initiative Study Group.

JAMA Oncol. 2018 Jun 1;4(6):806-813. doi: 10.1001/jamaoncol.2018.0104.

22.

Evidence-Based Thresholds for the Volume and Length of Stay Relationship in Total Hip Arthroplasty: Outcomes and Economies of Scale.

Ramkumar PN, Navarro SM, Frankel WC, Haeberle HS, Delanois RE, Mont MA.

J Arthroplasty. 2018 Jul;33(7):2031-2037. doi: 10.1016/j.arth.2018.01.059. Epub 2018 Feb 5. Erratum in: J Arthroplasty. 2018 Sep;33(9):3060-3061.

PMID:
29502962
23.

Lymph Node Metastasis in Colorectal Cancer.

Jin M, Frankel WL.

Surg Oncol Clin N Am. 2018 Apr;27(2):401-412. doi: 10.1016/j.soc.2017.11.011. Epub 2017 Dec 15. Review.

PMID:
29496097
24.

Dual Stain With SATB2 and CK20/Villin Is Useful to Distinguish Colorectal Carcinomas From Other Tumors.

Li Z, Rock JB, Roth R, Lehman A, Marsh WL, Suarez A, Frankel WL.

Am J Clin Pathol. 2018 Feb 17;149(3):241-246. doi: 10.1093/ajcp/aqx160.

25.

Colorectal Carcinomas With Isolated Loss of PMS2 Staining by Immunohistochemistry.

Alpert L, Pai RK, Srivastava A, McKinnon W, Wilcox R, Yantiss RK, Arcega R, Wang HL, Robert ME, Liu X, Pai RK, Zhao L, Westerhoff M, Hampel H, Kupfer S, Setia N, Xiao SY, Hart J, Frankel WL.

Arch Pathol Lab Med. 2018 Apr;142(4):523-528. doi: 10.5858/arpa.2017-0156-OA. Epub 2018 Jan 16.

PMID:
29336605
26.

Functions of the APC tumor suppressor protein dependent and independent of canonical WNT signaling: implications for therapeutic targeting.

Hankey W, Frankel WL, Groden J.

Cancer Metastasis Rev. 2018 Mar;37(1):159-172. doi: 10.1007/s10555-017-9725-6. Review.

27.

Mixed adenoneuroendocrine carcinoma: A review of pathologic characteristics.

Brathwaite SA, Smith SM, Wai L, Frankel W, Hays J, Yearsley MM, Abdel-Misih S.

Hum Pathol. 2018 Mar;73:184-191. doi: 10.1016/j.humpath.2017.12.009. Epub 2017 Dec 27.

PMID:
29288693
28.

Immunohistochemical Pitfalls: Common Mistakes in the Evaluation of Lynch Syndrome.

Markow M, Chen W, Frankel WL.

Surg Pathol Clin. 2017 Dec;10(4):977-1007. doi: 10.1016/j.path.2017.07.012. Review.

PMID:
29103543
29.

Alliance for clinical trials in oncology (ALLIANCE) trial A021501: preoperative extended chemotherapy vs. chemotherapy plus hypofractionated radiation therapy for borderline resectable adenocarcinoma of the head of the pancreas.

Katz MHG, Ou FS, Herman JM, Ahmad SA, Wolpin B, Marsh R, Behr S, Shi Q, Chuong M, Schwartz LH, Frankel W, Collisson E, Koay EJ, Hubbard JM, Leenstra JL, Meyerhardt J, O'Reilly E; Alliance for Clinical Trials on Oncology.

BMC Cancer. 2017 Jul 27;17(1):505. doi: 10.1186/s12885-017-3441-z.

30.

Epigenetic silencing of MLH1 in endometrial cancers is associated with larger tumor volume, increased rate of lymph node positivity and reduced recurrence-free survival.

Cosgrove CM, Cohn DE, Hampel H, Frankel WL, Jones D, McElroy JP, Suarez AA, Zhao W, Chen W, Salani R, Copeland LJ, O'Malley DM, Fowler JM, Yilmaz A, Chassen AS, Pearlman R, Goodfellow PJ, Backes FJ.

Gynecol Oncol. 2017 Sep;146(3):588-595. doi: 10.1016/j.ygyno.2017.07.003. Epub 2017 Jul 11.

31.

Comprehensive population-wide analysis of Lynch syndrome in Iceland reveals founder mutations in MSH6 and PMS2.

Haraldsdottir S, Rafnar T, Frankel WL, Einarsdottir S, Sigurdsson A, Hampel H, Snaebjornsson P, Masson G, Weng D, Arngrimsson R, Kehr B, Yilmaz A, Haraldsson S, Sulem P, Stefansson T, Shields PG, Sigurdsson F, Bekaii-Saab T, Moller PH, Steinarsdottir M, Alexiusdottir K, Hitchins M, Pritchard CC, de la Chapelle A, Jonasson JG, Goldberg RM, Stefansson K.

Nat Commun. 2017 May 3;8:14755. doi: 10.1038/ncomms14755.

32.

Dual Immunostain With SATB2 and CK20 Differentiates Appendiceal Mucinous Neoplasms From Ovarian Mucinous Neoplasms.

Li Z, Roth R, Rock JB, Lehman A, Marsh WL, Suarez A, Frankel WL.

Am J Clin Pathol. 2017 May 1;147(5):484-491. doi: 10.1093/ajcp/aqx023.

33.

Molecular genetics of microsatellite-unstable colorectal cancer for pathologists.

Chen W, Swanson BJ, Frankel WL.

Diagn Pathol. 2017 Mar 4;12(1):24. doi: 10.1186/s13000-017-0613-8. Review.

34.

Temporal trends in minimally invasive myomectomy before and after the US Food and Drug Administration recommendation against electric morcellation.

Pereira N, Frankel WC, Hutchinson AP, Patel HH, Mostisser C, Elias RT.

Int J Gynaecol Obstet. 2017 Jun;137(3):295-300. doi: 10.1002/ijgo.12128. Epub 2017 Mar 16.

PMID:
28218964
35.

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.

Wolfson RL, Chantranupong L, Wyant GA, Gu X, Orozco JM, Shen K, Condon KJ, Petri S, Kedir J, Scaria SM, Abu-Remaileh M, Frankel WN, Sabatini DM.

Nature. 2017 Mar 16;543(7645):438-442. doi: 10.1038/nature21423. Epub 2017 Feb 15.

36.

Challenges to "Classic" Esophageal Candidiasis: Looks Are Usually Deceiving.

Alsomali MI, Arnold MA, Frankel WL, Graham RP, Hart PA, Lam-Himlin DM, Naini BV, Voltaggio L, Arnold CA.

Am J Clin Pathol. 2017 Jan 1;147(1):33-42. doi: 10.1093/ajcp/aqw210.

PMID:
28158394
37.

Reply to L. Casadaban et al.

Niedzwiecki D, Frankel WL, Venook AP, Ye X, Friedman PN, Goldberg RM, Mayer RJ, Colacchio TA, Mulligan JM, Davison TS, O'Brien E, Kerr P, Johnston PG, Kennedy RD, Harkin DP, Schilsky RL, Bertagnolli MM, Warren RS, Innocenti F.

J Clin Oncol. 2017 Apr 20;35(12):1373-1374. doi: 10.1200/JCO.2016.71.2646. Epub 2017 Jan 23. No abstract available.

PMID:
28113023
38.

Crospovidone and Microcrystalline Cellulose: A Novel Description of Pharmaceutical Fillers in the Gastrointestinal Tract.

Shaddy SM, Arnold MA, Shilo K, Frankel WL, Harzman AE, Stanich PP, Singhi AD, Yearsley MM, Arnold CA.

Am J Surg Pathol. 2017 Apr;41(4):564-569. doi: 10.1097/PAS.0000000000000790.

PMID:
28009603
39.

Blocking the CCL2-CCR2 Axis Using CCL2-Neutralizing Antibody Is an Effective Therapy for Hepatocellular Cancer in a Mouse Model.

Teng KY, Han J, Zhang X, Hsu SH, He S, Wani NA, Barajas JM, Snyder LA, Frankel WL, Caligiuri MA, Jacob ST, Yu J, Ghoshal K.

Mol Cancer Ther. 2017 Feb;16(2):312-322. doi: 10.1158/1535-7163.MCT-16-0124. Epub 2016 Dec 15.

40.

Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer.

Pearlman R, Frankel WL, Swanson B, Zhao W, Yilmaz A, Miller K, Bacher J, Bigley C, Nelsen L, Goodfellow PJ, Goldberg RM, Paskett E, Shields PG, Freudenheim JL, Stanich PP, Lattimer I, Arnold M, Liyanarachchi S, Kalady M, Heald B, Greenwood C, Paquette I, Prues M, Draper DJ, Lindeman C, Kuebler JP, Reynolds K, Brell JM, Shaper AA, Mahesh S, Buie N, Weeman K, Shine K, Haut M, Edwards J, Bastola S, Wickham K, Khanduja KS, Zacks R, Pritchard CC, Shirts BH, Jacobson A, Allen B, de la Chapelle A, Hampel H; Ohio Colorectal Cancer Prevention Initiative Study Group.

JAMA Oncol. 2017 Apr 1;3(4):464-471. doi: 10.1001/jamaoncol.2016.5194.

41.

Hydrophilic Polymer-associated Ischemic Enterocolitis.

Chavez JA, Chen W, Frankel WL, Arnold CA.

Am J Surg Pathol. 2017 Feb;41(2):271-276. doi: 10.1097/PAS.0000000000000765.

PMID:
27819873
42.

Inhibition of microRNA 128 promotes excitability of cultured cortical neuronal networks.

McSweeney KM, Gussow AB, Bradrick SS, Dugger SA, Gelfman S, Wang Q, Petrovski S, Frankel WN, Boland MJ, Goldstein DB.

Genome Res. 2016 Oct;26(10):1411-1416. Epub 2016 Aug 11.

43.

Primary Pancreatic Secretinoma: Further Evidence Supporting Secretin as a Diarrheogenic Hormone.

Chey WY, Frankel WL, Roy S, Datta S, Sen CK, Dillhoff M, Muscarella P, Soergel KH, Tompkins RK, Chang TM, Bradley EL 3rd, Ellison EC.

Ann Surg. 2017 Aug;266(2):346-352. doi: 10.1097/SLA.0000000000001938.

PMID:
27501174
44.

Association Between Results of a Gene Expression Signature Assay and Recurrence-Free Interval in Patients With Stage II Colon Cancer in Cancer and Leukemia Group B 9581 (Alliance).

Niedzwiecki D, Frankel WL, Venook AP, Ye X, Friedman PN, Goldberg RM, Mayer RJ, Colacchio TA, Mulligan JM, Davison TS, O'Brien E, Kerr P, Johnston PG, Kennedy RD, Harkin DP, Schilsky RL, Bertagnolli MM, Warren RS, Innocenti F.

J Clin Oncol. 2016 Sep 1;34(25):3047-53. doi: 10.1200/JCO.2015.65.4699. Epub 2016 Jul 18.

45.

A phase I pilot study evaluating the beneficial effects of black raspberries in patients with Barrett's esophagus.

Kresty LA, Fromkes JJ, Frankel WL, Hammond CD, Seeram NP, Baird M, Stoner GD.

Oncotarget. 2016 Jul 7;9(82):35356-35372. doi: 10.18632/oncotarget.10457. eCollection 2018 Oct 19.

46.

Appendiceal Mixed Adeno-Neuroendocrine Carcinoma: A Population-Based Study of the Surveillance, Epidemiology, and End Results Registry.

Brathwaite S, Yearsley MM, Bekaii-Saab T, Wei L, Schmidt CR, Dillhoff ME, Frankel WL, Hays JL, Wu C, Abdel-Misih S.

Front Oncol. 2016 Jun 13;6:148. doi: 10.3389/fonc.2016.00148. eCollection 2016.

47.

Dynamin 1 isoform roles in a mouse model of severe childhood epileptic encephalopathy.

Asinof S, Mahaffey C, Beyer B, Frankel WN, Boumil R.

Neurobiol Dis. 2016 Nov;95:1-11. doi: 10.1016/j.nbd.2016.06.014. Epub 2016 Jun 28.

48.

Discordant Mismatch Repair Protein Immunoreactivity in Lynch Syndrome-Associated Neoplasms:  A Recommendation for Screening Synchronous/Metachronous Neoplasms.

Roth RM, Haraldsdottir S, Hampel H, Arnold CA, Frankel WL.

Am J Clin Pathol. 2016 Jul;146(1):50-6. doi: 10.1093/ajcp/aqw067. Epub 2016 Jun 29.

PMID:
27357288
49.

Liver Metastases of Neuroendocrine Tumors Rarely Show Overlapping Immunoprofile with Hepatocellular Carcinomas.

Jin M, Zhou X, Yearsley M, Frankel WL.

Endocr Pathol. 2016 Sep;27(3):253-8. doi: 10.1007/s12022-016-9442-7.

PMID:
27300354
50.

Preoperative Modified FOLFIRINOX Treatment Followed by Capecitabine-Based Chemoradiation for Borderline Resectable Pancreatic Cancer: Alliance for Clinical Trials in Oncology Trial A021101.

Katz MH, Shi Q, Ahmad SA, Herman JM, Marsh Rde W, Collisson E, Schwartz L, Frankel W, Martin R, Conway W, Truty M, Kindler H, Lowy AM, Bekaii-Saab T, Philip P, Talamonti M, Cardin D, LoConte N, Shen P, Hoffman JP, Venook AP.

JAMA Surg. 2016 Aug 17;151(8):e161137. doi: 10.1001/jamasurg.2016.1137. Epub 2016 Aug 17.

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