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Items: 1 to 50 of 644

1.

Evaluation of kinetic data: What the numbers tell us about PRMTs.

Frankel A, Brown JI.

Biochim Biophys Acta Proteins Proteom. 2018 Oct 17. pii: S1570-9639(18)30179-1. doi: 10.1016/j.bbapap.2018.10.010. [Epub ahead of print] Review.

PMID:
30342239
2.

Phase 1 study of ARQ 761, a β-lapachone analogue that promotes NQO1-mediated programmed cancer cell necrosis.

Gerber DE, Beg MS, Fattah F, Frankel AE, Fatunde O, Arriaga Y, Dowell JE, Bisen A, Leff RD, Meek CC, Putnam WC, Kallem RR, Subramaniyan I, Dong Y, Bolluyt J, Sarode V, Luo X, Xie Y, Schwartz B, Boothman DA.

Br J Cancer. 2018 Oct;119(8):928-936. doi: 10.1038/s41416-018-0278-4. Epub 2018 Oct 15.

PMID:
30318513
3.

Discovery of a Branched Peptide That Recognizes the Rev Response Element (RRE) RNA and Blocks HIV-1 Replication.

Dai Y, Wynn JE, Peralta AN, Sherpa C, Jayaraman B, Li H, Verma A, Frankel AD, Le Grice SF, Santos WL.

J Med Chem. 2018 Nov 8;61(21):9611-9620. doi: 10.1021/acs.jmedchem.8b01076. Epub 2018 Oct 18.

PMID:
30289719
4.

An optical nanoreporter of endolysosomal lipid accumulation reveals enduring effects of diet on hepatic macrophages in vivo.

Galassi TV, Jena PV, Shah J, Ao G, Molitor E, Bram Y, Frankel A, Park J, Jessurun J, Ory DS, Haimovitz-Friedman A, Roxbury D, Mittal J, Zheng M, Schwartz RE, Heller DA.

Sci Transl Med. 2018 Oct 3;10(461). pii: eaar2680. doi: 10.1126/scitranslmed.aar2680.

PMID:
30282694
5.

Management of adults with diabetes on the haemodialysis unit: summary of guidance from the Joint British Diabetes Societies and the Renal Association.

Frankel AH, Kazempour-Ardebili S, Bedi R, Chowdhury TA, De P, El-Sherbini N, Game F, Gray S, Hardy D, James J, Kong MF, Ramlan G, Southcott E, Winocour P.

Diabet Med. 2018 Aug;35(8):1018-1026. doi: 10.1111/dme.13676.

PMID:
30152585
6.

Tumor endothelial marker 8 promotes cancer progression and metastasis.

Høye AM, Tolstrup SD, Horton ER, Nicolau M, Frost H, Woo JH, Mauldin JP, Frankel AE, Cox TR, Erler JT.

Oncotarget. 2018 Jul 10;9(53):30173-30188. doi: 10.18632/oncotarget.25734. eCollection 2018 Jul 10.

7.

Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection.

Winer BY, Shirvani-Dastgerdi E, Bram Y, Sellau J, Low BE, Johnson H, Huang T, Hrebikova G, Heller B, Sharon Y, Giersch K, Gerges S, Seneca K, Pais MA, Frankel AS, Chiriboga L, Cullen J, Nahass RG, Lutgehetmann M, Toettcher JE, Wiles MV, Schwartz RE, Ploss A.

Sci Transl Med. 2018 Jun 27;10(447). pii: eaap9328. doi: 10.1126/scitranslmed.aap9328.

PMID:
29950446
8.

Pneumatic oscillating microsagittal saw: a novel method for removal of a rectal foreign body.

McCombe AJ, Frankel AJ, Morris B.

ANZ J Surg. 2018 Jun 12. doi: 10.1111/ans.14739. [Epub ahead of print] No abstract available.

PMID:
29895101
9.

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

Faust TB, Li Y, Bacon CW, Jang GM, Weiss A, Jayaraman B, Newton BW, Krogan NJ, D'Orso I, Frankel AD.

Elife. 2018 May 30;7. pii: e31879. doi: 10.7554/eLife.31879.

10.

Central airway obstruction caused by adenoid cystic carcinoma in pregnancy: a case report and review of the literature.

Shafiee S, Adno A, French B, Johansson C, Frankel A, Williamson JP.

Respirol Case Rep. 2018 Apr 20;6(5):e00317. doi: 10.1002/rcr2.317. eCollection 2018 Jul.

11.

Complications of Polydioxanone Foil Use in Nasal Surgery: A Case Series.

Wang LL, Frankel AS, Friedman O.

Facial Plast Surg. 2018 Jun;34(3):312-317. doi: 10.1055/s-0038-1632399. Epub 2018 Apr 27.

PMID:
29702721
12.

Building a safety culture in global health: lessons from Guatemala.

Rice HE, Lou-Meda R, Saxton AT, Johnston BE, Ramirez CC, Mendez S, Rice EN, Aidar B, Taicher B, Baumgartner JN, Milne J, Frankel AS, Sexton JB.

BMJ Glob Health. 2018 Mar 9;3(2):e000630. doi: 10.1136/bmjgh-2017-000630. eCollection 2018. Review.

13.

Sexting, Risk Behavior, and Mental Health in Adolescents: An Examination of 2015 Pennsylvania Youth Risk Behavior Survey Data.

Frankel AS, Bass SB, Patterson F, Dai T, Brown D.

J Sch Health. 2018 Mar;88(3):190-199. doi: 10.1111/josh.12596.

PMID:
29399839
14.

Defining Phenotypes in Diabetic Nephropathy: a novel approach using a cross-sectional analysis of a single centre cohort.

Montero RM, Herath A, Qureshi A, Esfandiari E, Pusey CD, Frankel AH, Tam FWK.

Sci Rep. 2018 Jan 8;8(1):53. doi: 10.1038/s41598-017-18595-1.

15.

Kinetic Analysis of PRMT1 Reveals Multifactorial Processivity and a Sequential Ordered Mechanism.

Brown JI, Koopmans T, van Strien J, Martin NI, Frankel A.

Chembiochem. 2018 Jan 4;19(1):85-99. doi: 10.1002/cbic.201700521. Epub 2017 Nov 29.

PMID:
29112789
16.

Providing feedback following Leadership WalkRounds is associated with better patient safety culture, higher employee engagement and lower burnout.

Sexton JB, Adair KC, Leonard MW, Frankel TC, Proulx J, Watson SR, Magnus B, Bogan B, Jamal M, Schwendimann R, Frankel AS.

BMJ Qual Saf. 2018 Apr;27(4):261-270. doi: 10.1136/bmjqs-2016-006399. Epub 2017 Oct 9.

17.

Making Sense of Multifunctional Proteins: Human Immunodeficiency Virus Type 1 Accessory and Regulatory Proteins and Connections to Transcription.

Faust TB, Binning JM, Gross JD, Frankel AD.

Annu Rev Virol. 2017 Sep 29;4(1):241-260. doi: 10.1146/annurev-virology-101416-041654. Review.

18.

Metagenomic Shotgun Sequencing and Unbiased Metabolomic Profiling Identify Specific Human Gut Microbiota and Metabolites Associated with Immune Checkpoint Therapy Efficacy in Melanoma Patients.

Frankel AE, Coughlin LA, Kim J, Froehlich TW, Xie Y, Frenkel EP, Koh AY.

Neoplasia. 2017 Oct;19(10):848-855. doi: 10.1016/j.neo.2017.08.004. Epub 2017 Sep 15.

19.

Modification of Chin Projection and Aesthetics With OnabotulinumtoxinA Injection.

Hsu AK, Frankel AS.

JAMA Facial Plast Surg. 2017 Dec 1;19(6):522-527. doi: 10.1001/jamafacial.2017.0606.

PMID:
28750118
20.

Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia.

Stein EM, DiNardo CD, Pollyea DA, Fathi AT, Roboz GJ, Altman JK, Stone RM, DeAngelo DJ, Levine RL, Flinn IW, Kantarjian HM, Collins R, Patel MR, Frankel AE, Stein A, Sekeres MA, Swords RT, Medeiros BC, Willekens C, Vyas P, Tosolini A, Xu Q, Knight RD, Yen KE, Agresta S, de Botton S, Tallman MS.

Blood. 2017 Aug 10;130(6):722-731. doi: 10.1182/blood-2017-04-779405. Epub 2017 Jun 6.

21.

Complicated silicosis resulting from occupational exposure to engineered stone products.

Matar E, Frankel A, Blake LKM, Silverstone EJ, Johnson AR, Yates DH.

Med J Aust. 2017 May 15;206(9):385-386. No abstract available.

PMID:
28490299
22.

A STING-activating nanovaccine for cancer immunotherapy.

Luo M, Wang H, Wang Z, Cai H, Lu Z, Li Y, Du M, Huang G, Wang C, Chen X, Porembka MR, Lea J, Frankel AE, Fu YX, Chen ZJ, Gao J.

Nat Nanotechnol. 2017 Jul;12(7):648-654. doi: 10.1038/nnano.2017.52. Epub 2017 Apr 24.

23.

Identification and Optimization of Thienopyridine Carboxamides as Inhibitors of HIV Regulatory Complexes.

Nakamura RL, Burlingame MA, Yang S, Crosby DC, Talbot DJ, Chui K, Frankel AD, Renslo AR.

Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e02366-16. doi: 10.1128/AAC.02366-16. Print 2017 Jul.

24.

PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription.

Faust TB, Li Y, Jang GM, Johnson JR, Yang S, Weiss A, Krogan NJ, Frankel AD.

Sci Rep. 2017 Mar 27;7:45394. doi: 10.1038/srep45394.

25.

Academic Cancer Center Phase I Program Development.

Frankel AE, Flaherty KT, Weiner GJ, Chen R, Azad NS, Pishvaian MJ, Thompson JA, Taylor MH, Mahadevan D, Lockhart AC, Vaishampayan UN, Berlin JD, Smith DC, Sarantopoulos J, Riese M, Saleh MN, Ahn C, Frenkel EP.

Oncologist. 2017 Apr;22(4):369-374. doi: 10.1634/theoncologist.2016-0409. Epub 2017 Mar 17.

26.

Digoxin Plus Trametinib Therapy Achieves Disease Control in BRAF Wild-Type Metastatic Melanoma Patients.

Frankel AE, Eskiocak U, Gill JG, Yuan S, Ramesh V, Froehlich TW, Ahn C, Morrison SJ.

Neoplasia. 2017 Apr;19(4):255-260. doi: 10.1016/j.neo.2017.01.010. Epub 2017 Mar 6.

27.

PRMT2 interacts with splicing factors and regulates the alternative splicing of BCL-X.

Vhuiyan MI, Pak ML, Park MA, Thomas D, Lakowski TM, Chalfant CE, Frankel A.

J Biochem. 2017 Jul 1;162(1):17-25. doi: 10.1093/jb/mvw102.

28.

Assessment of complex dissociative disorder patients and simulated dissociation in forensic contexts.

Brand BL, Webermann AR, Frankel AS.

Int J Law Psychiatry. 2016 Nov - Dec;49(Pt B):197-204. doi: 10.1016/j.ijlp.2016.10.006. Epub 2016 Oct 29.

PMID:
28029435
29.

Functional Segregation of Overlapping Genes in HIV.

Fernandes JD, Faust TB, Strauli NB, Smith C, Crosby DC, Nakamura RL, Hernandez RD, Frankel AD.

Cell. 2016 Dec 15;167(7):1762-1773.e12. doi: 10.1016/j.cell.2016.11.031.

30.

Non-cell-autonomous Effects of Autophagy Inhibition in Tumor Cells Promote Growth of Drug-resistant Cells.

Thorburn J, Staskiewicz L, Goodall ML, Dimberg L, Frankel AE, Ford HL, Thorburn A.

Mol Pharmacol. 2017 Jan;91(1):58-64. Epub 2016 Nov 9.

31.

Blastic plasmacytoid dendritic cell neoplasm with t(11;19)(q23;p13.3);KMT2A(MLL) rearranged: a diagnostic challenge.

Gehlbach D, Koduru P, John G, Fuda F, Frankel AE, Chen W.

Br J Haematol. 2017 Jan;176(1):8. doi: 10.1111/bjh.14389. Epub 2016 Oct 24. No abstract available.

PMID:
27774582
32.

Oligomeric viral proteins: small in size, large in presence.

Jayaraman B, Smith AM, Fernandes JD, Frankel AD.

Crit Rev Biochem Mol Biol. 2016 Sep;51(5):379-394. Epub 2016 Aug 14. Review.

33.
34.

Erratum: Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma.

Eskiocak U, Ramesh V, Gill JG, Zhao Z, Yuan SW, Wang M, Vandergriff T, Shackleton M, Quintana E, Frankel AE, Johnson TM, DeBerardinis RJ, Morrison SJ.

Nat Commun. 2016 Sep 29;7:13080. doi: 10.1038/ncomms13080. No abstract available.

35.

Developing EZH2-Targeted Therapy for Lung Cancer.

Frankel AE, Liu X, Minna JD.

Cancer Discov. 2016 Sep;6(9):949-52. doi: 10.1158/2159-8290.CD-16-0800.

36.

Pluripotent Stem Cell-Derived Hepatocyte-like Cells: A Tool to Study Infectious Disease.

Schwartz RE, Bram Y, Frankel A.

Curr Pathobiol Rep. 2016 Sep;4(3):147-156. Epub 2016 Jul 30.

37.

Discharging dynamics in an electrolytic cell.

Feicht SE, Frankel AE, Khair AS.

Phys Rev E. 2016 Jul;94(1-1):012601. doi: 10.1103/PhysRevE.94.012601. Epub 2016 Jul 5.

PMID:
27575173
38.

Structural basis of arginine asymmetrical dimethylation by PRMT6.

Wu H, Zheng W, Eram MS, Vhuiyan M, Dong A, Zeng H, He H, Brown P, Frankel A, Vedadi M, Luo M, Min J.

Biochem J. 2016 Oct 1;473(19):3049-63. doi: 10.1042/BCJ20160537. Epub 2016 Aug 1.

39.

Assessment of morbidity following regional nodal dissection in the axilla and groin for metastatic melanoma.

Theodore JE, Frankel AJ, Thomas JM, Barbour AP, Bayley GJ, Allan CP, Wagels M, Smithers BM.

ANZ J Surg. 2017 Jan;87(1-2):44-48. doi: 10.1111/ans.13526. Epub 2016 Apr 21.

PMID:
27102082
40.

A structurally plastic ribonucleoprotein complex mediates post-transcriptional gene regulation in HIV-1.

Fernandes JD, Booth DS, Frankel AD.

Wiley Interdiscip Rev RNA. 2016 Jul;7(4):470-86. doi: 10.1002/wrna.1342. Epub 2016 Mar 1. Review.

41.
42.

Stochastic Modeling of Behavioral Response to Anthropogenic Sounds.

Frankel AS, Ellison WT, Vigness-Raposa KJ, Giard JL, Southall BL.

Adv Exp Med Biol. 2016;875:321-9. doi: 10.1007/978-1-4939-2981-8_38.

PMID:
26610975
43.

Current Status of Development of Methods to Assess Effects of Cumulative or Aggregated Underwater Sounds on Marine Mammals.

Fleishman E, Streever B, Angliss R, Clark CW, Ellison WT, Frankel A, Gedamke J, Leu M, McKenna M, Racca R, Simmons S, Suydam R.

Adv Exp Med Biol. 2016;875:303-11. doi: 10.1007/978-1-4939-2981-8_36.

PMID:
26610973
44.

Engraftment of human induced pluripotent stem cell-derived hepatocytes in immunocompetent mice via 3D co-aggregation and encapsulation.

Song W, Lu YC, Frankel AS, An D, Schwartz RE, Ma M.

Sci Rep. 2015 Nov 23;5:16884. doi: 10.1038/srep16884.

45.

An Analysis of Lateral Crural Repositioning and Its Effect on Alar Rim Position.

Paquet CA, Choroomi S, Frankel AS.

JAMA Facial Plast Surg. 2016 Mar-Apr;18(2):89-94. doi: 10.1001/jamafacial.2015.1625.

PMID:
26562290
46.

Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF).

Bekdash A, Darwish M, Timsah Z, Kassab E, Ghanem H, Najjar V, Ghosn M, Nasser S, El-Hajj H, Bazerbachi A, Liu S, Leppla SH, Frankel AE, Abi-Habib RJ.

Transl Oncol. 2015 Oct;8(5):347-57. doi: 10.1016/j.tranon.2015.07.001.

47.

Thermodynamics of Rev-RNA interactions in HIV-1 Rev-RRE assembly.

Jayaraman B, Mavor D, Gross JD, Frankel AD.

Biochemistry. 2015 Oct 27;54(42):6545-54. doi: 10.1021/acs.biochem.5b00876. Epub 2015 Oct 13.

48.

Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency.

Burrage LC, Sun Q, Elsea SH, Jiang MM, Nagamani SC, Frankel AE, Stone E, Alters SE, Johnson DE, Rowlinson SW, Georgiou G; Members of Urea Cycle Disorders Consortium, Lee BH.

Hum Mol Genet. 2015 Nov 15;24(22):6417-27. doi: 10.1093/hmg/ddv352. Epub 2015 Sep 10.

49.

Selective Targeting of Cells via Bispecific Molecules That Exploit Coexpression of Two Intracellular Proteins.

Dunyak BM, Nakamura RL, Frankel AD, Gestwicki JE.

ACS Chem Biol. 2015 Nov 20;10(11):2441-7. doi: 10.1021/acschembio.5b00426. Epub 2015 Sep 2.

50.

Arginine methylation in yeast proteins during stationary-phase growth and heat shock.

Lakowski TM, Pak ML, Szeitz A, Thomas D, Vhuiyan MI, Clement B, Frankel A.

Amino Acids. 2015 Dec;47(12):2561-71. doi: 10.1007/s00726-015-2047-5. Epub 2015 Jul 19.

PMID:
26189025

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