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Items: 1 to 50 of 96

1.

Clinical features of electric powered indoor/outdoor wheelchair users with spinal cord injuries: A cross-sectional study.

De Souza LH, Frank AO.

Assist Technol. 2018 Jul 23:1-8. doi: 10.1080/10400435.2018.1503205. [Epub ahead of print]

PMID:
30036176
2.

Clinical features of children and adults with a muscular dystrophy using powered indoor/outdoor wheelchairs: disease features, comorbidities and complications of disability.

Frank AO, De Souza LH.

Disabil Rehabil. 2018 May;40(9):1007-1013. doi: 10.1080/09638288.2017.1292322. Epub 2017 Feb 25.

PMID:
28338349
3.

Problematic clinical features of children and adults with cerebral palsy who use electric powered indoor/outdoor wheelchairs: A cross-sectional study.

Frank AO, De Souza LH.

Assist Technol. 2017 Summer;29(2):68-75. doi: 10.1080/10400435.2016.1201873. Epub 2016 Oct 7.

PMID:
27715489
4.

Facilitating unambiguous NMR assignments and enabling higher probe density through selective labeling of all methyl containing amino acids.

Proudfoot A, Frank AO, Ruggiu F, Mamo M, Lingel A.

J Biomol NMR. 2016 May;65(1):15-27. doi: 10.1007/s10858-016-0032-2. Epub 2016 Apr 29.

PMID:
27130242
5.

Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A.

Patrone JD, Pelz NF, Bates BS, Souza-Fagundes EM, Vangamudi B, Camper DV, Kuznetsov AG, Browning CF, Feldkamp MD, Frank AO, Gilston BA, Olejniczak ET, Rossanese OW, Waterson AG, Chazin WJ, Fesik SW.

ChemMedChem. 2016 Apr 19;11(8):893-9. doi: 10.1002/cmdc.201500479. Epub 2016 Jan 8.

6.

Rare diseases: matching wheelchair users with rare metabolic, neuromuscular or neurological disorders to electric powered indoor/outdoor wheelchairs (EPIOCs).

De Souza LH, Frank AO.

Disabil Rehabil. 2016 Aug;38(16):1547-56. doi: 10.3109/09638288.2015.1106599. Epub 2015 Dec 30.

7.

cis-Peptide Bonds: A Key for Intestinal Permeability of Peptides? .

Marelli UK, Ovadia O, Frank AO, Chatterjee J, Gilon C, Hoffman A, Kessler H.

Chemistry. 2015 Oct 19;21(43):15148-52. doi: 10.1002/chem.201501600. Epub 2015 Sep 4.

PMID:
26337831
8.

Management of chronic pain: seek symptoms of post-traumatic stress disorder.

Frank AO.

BMJ. 2015 Mar 10;350:h1291. doi: 10.1136/bmj.h1291. No abstract available.

PMID:
25759265
9.

Diphenylpyrazoles as replication protein a inhibitors.

Waterson AG, Kennedy JP, Patrone JD, Pelz NF, Feldkamp MD, Frank AO, Vangamudi B, Souza-Fagundes EM, Rossanese OW, Chazin WJ, Fesik SW.

ACS Med Chem Lett. 2014 Nov 11;6(2):140-5. doi: 10.1021/ml5003629. eCollection 2015 Feb 12.

10.

Direct prediction of residual dipolar couplings of small molecules in a stretched gel by stochastic molecular dynamics simulations.

Frank AO, Freudenberger JC, Shaytan AK, Kessler H, Luy B.

Magn Reson Chem. 2015 Mar;53(3):213-7. doi: 10.1002/mrc.4181. Epub 2015 Jan 22.

PMID:
25612077
11.

Assessing pain intensity following spinal cord injury: should rating scales measure 'overall' or 'maximal' values?

Frank AO, Spyridonis F, Ghinea G.

Int J Rehabil Res. 2015 Mar;38(1):92-4. doi: 10.1097/MRR.0000000000000093.

PMID:
25419691
12.

Receptor-bound conformation of cilengitide better represented by its solution-state structure than the solid-state structure.

Marelli UK, Frank AO, Wahl B, La Pietra V, Novellino E, Marinelli L, Herdtweck E, Groll M, Kessler H.

Chemistry. 2014 Oct 27;20(44):14201-6. doi: 10.1002/chem.201403839. Epub 2014 Sep 22.

PMID:
25251673
13.

Problematic clinical features of powered wheelchair users with severely disabling multiple sclerosis.

De Souza LH, Frank AO.

Disabil Rehabil. 2015;37(11):990-6. doi: 10.3109/09638288.2014.949356. Epub 2014 Aug 11.

PMID:
25109500
14.

Discovery of a potent stapled helix peptide that binds to the 70N domain of replication protein A.

Frank AO, Vangamudi B, Feldkamp MD, Souza-Fagundes EM, Luzwick JW, Cortez D, Olejniczak ET, Waterson AG, Rossanese OW, Chazin WJ, Fesik SW.

J Med Chem. 2014 Mar 27;57(6):2455-61. doi: 10.1021/jm401730y. Epub 2014 Feb 19.

15.

Discovery of a potent inhibitor of replication protein a protein-protein interactions using a fragment-linking approach.

Frank AO, Feldkamp MD, Kennedy JP, Waterson AG, Pelz NF, Patrone JD, Vangamudi B, Camper DV, Rossanese OW, Chazin WJ, Fesik SW.

J Med Chem. 2013 Nov 27;56(22):9242-50. doi: 10.1021/jm401333u. Epub 2013 Nov 11.

16.

Surface reengineering of RPA70N enables cocrystallization with an inhibitor of the replication protein A interaction motif of ATR interacting protein.

Feldkamp MD, Frank AO, Kennedy JP, Patrone JD, Vangamudi B, Waterson AG, Fesik SW, Chazin WJ.

Biochemistry. 2013 Sep 17;52(37):6515-24. doi: 10.1021/bi400542z. Epub 2013 Sep 6.

17.

Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A.

Patrone JD, Kennedy JP, Frank AO, Feldkamp MD, Vangamudi B, Pelz NF, Rossanese OW, Waterson AG, Chazin WJ, Fesik SW.

ACS Med Chem Lett. 2013 Jul 11;4(7):601-605.

18.

Recipients of electric-powered indoor/outdoor wheelchairs provided by a national health service: a cross-sectional study.

Frank AO, De Souza LH.

Arch Phys Med Rehabil. 2013 Dec;94(12):2403-9. doi: 10.1016/j.apmr.2013.07.010. Epub 2013 Jul 23.

PMID:
23891668
19.

Pain management following new and long-standing spinal cord injury: a pilot study of changes in pain intensity experienced during the day.

Frank AO, Gawronski J, Spyridonis F, Ghinea G.

Int J Rehabil Res. 2013 Dec;36(4):379-82. doi: 10.1097/MRR.0b013e3283646b74.

PMID:
23881158
20.

Starting vocational rehabilitation early after stroke.

Frank AO.

BMJ. 2013 Jul 16;347:f4278. doi: 10.1136/bmj.f4278. No abstract available.

PMID:
23861408
21.

Fragment-based drug discovery using NMR spectroscopy.

Harner MJ, Frank AO, Fesik SW.

J Biomol NMR. 2013 Jun;56(2):65-75. doi: 10.1007/s10858-013-9740-z. Epub 2013 May 18. Review.

22.

Attitudes of patients toward adoption of 3D technology in pain assessment: qualitative perspective.

Spyridonis F, Ghinea G, Frank AO.

J Med Internet Res. 2013 Apr 10;15(4):e55. doi: 10.2196/jmir.2427.

23.

A conformationally frozen peptoid boosts CXCR4 affinity and anti-HIV activity.

Demmer O, Frank AO, Hagn F, Schottelius M, Marinelli L, Cosconati S, Brack-Werner R, Kremb S, Wester HJ, Kessler H.

Angew Chem Int Ed Engl. 2012 Aug 6;51(32):8110-3. doi: 10.1002/anie.201202090. Epub 2012 Jul 3. No abstract available.

PMID:
22760863
24.

Intestinal permeability of cyclic peptides: common key backbone motifs identified.

Beck JG, Chatterjee J, Laufer B, Kiran MU, Frank AO, Neubauer S, Ovadia O, Greenberg S, Gilon C, Hoffman A, Kessler H.

J Am Chem Soc. 2012 Jul 25;134(29):12125-33. doi: 10.1021/ja303200d. Epub 2012 Jul 12.

PMID:
22737969
25.

An interactive 3-D application for pain management: Results from a pilot study in spinal cord injury rehabilitation.

Spyridonis F, Gawronski J, Ghinea G, Frank AO.

Comput Methods Programs Biomed. 2012 Oct;108(1):356-66. doi: 10.1016/j.cmpb.2012.02.005. Epub 2012 Mar 7.

PMID:
22401773
26.

A high-throughput fluorescence polarization anisotropy assay for the 70N domain of replication protein A.

Souza-Fagundes EM, Frank AO, Feldkamp MD, Dorset DC, Chazin WJ, Rossanese OW, Olejniczak ET, Fesik SW.

Anal Biochem. 2012 Feb 15;421(2):742-9. doi: 10.1016/j.ab.2011.11.025. Epub 2011 Dec 1.

27.

The pain experiences of powered wheelchair users.

Frank AO, De Souza LH, Frank JL, Neophytou C.

Disabil Rehabil. 2012;34(9):770-8. doi: 10.3109/09638288.2011.619620. Epub 2011 Oct 21.

PMID:
22013954
28.

Increasing αvβ3 selectivity of the anti-angiogenic drug cilengitide by N-methylation.

Mas-Moruno C, Beck JG, Doedens L, Frank AO, Marinelli L, Cosconati S, Novellino E, Kessler H.

Angew Chem Int Ed Engl. 2011 Sep 26;50(40):9496-500. doi: 10.1002/anie.201102971. Epub 2011 Aug 25. No abstract available.

PMID:
21948451
29.

Conformational control of integrin-subtype selectivity in isoDGR peptide motifs: a biological switch.

Frank AO, Otto E, Mas-Moruno C, Schiller HB, Marinelli L, Cosconati S, Bochen A, Vossmeyer D, Zahn G, Stragies R, Novellino E, Kessler H.

Angew Chem Int Ed Engl. 2010 Nov 22;49(48):9278-81. doi: 10.1002/anie.201004363. No abstract available.

PMID:
20957712
30.

Patients' experiences of the impact of chronic back pain on family life and work.

De Souza L, Frank AO.

Disabil Rehabil. 2011;33(4):310-8. doi: 10.3109/09638288.2010.490865. Epub 2010 Jun 4.

PMID:
20521998
31.

The impact of amino acid side chain mutations in conformational design of peptides and proteins.

Laufer B, Frank AO, Chatterjee J, Neubauer T, Mas-Moruno C, Kummerlöwe G, Kessler H.

Chemistry. 2010 May 10;16(18):5385-90. doi: 10.1002/chem.201000545.

PMID:
20358563
32.

Binding of TCA to the prion protein: mechanism, implication for therapy, and application as probe for complex formation of bio-macromolecules.

Mangels C, Frank AO, Ziegler J, Klingenstein R, Schweimer K, Willbold D, Korth C, Rösch P, Schwarzinger S.

J Biomol Struct Dyn. 2009 Oct;27(2):163-70.

PMID:
19583442
33.

Making double-minded peptides strong-willed? The side chain impact on the backbone conformation of N-methylated cyclic pentapeptides.

Laufer B, Chatterjee J, Frank AO, Kessler H.

Adv Exp Med Biol. 2009;611:157-8. No abstract available.

PMID:
19400138
34.

Electric powered wheelchairs for those with muscular dystrophy: problems of posture, pain and deformity.

Richardson M, Frank AO.

Disabil Rehabil Assist Technol. 2009 May;4(3):181-8. doi: 10.1080/17483100802543114.

PMID:
19199130
35.

Deuterated polymer gels for measuring anisotropic NMR parameters with strongly reduced artefacts.

Kummerlöwe G, Knör S, Frank AO, Paululat T, Kessler H, Luy B.

Chem Commun (Camb). 2008 Nov 30;(44):5722-4. doi: 10.1039/b812905c. Epub 2008 Oct 6.

PMID:
19009060
36.

Can N-methylated amino acids serve as substitutes for prolines in conformational design of cyclic pentapeptides?

Laufer B, Chatterjee J, Frank AO, Kessler H.

J Pept Sci. 2009 Mar;15(3):141-6. doi: 10.1002/psc.1076.

PMID:
18985637
37.

Biophysics: the sweetest candy for the virus.

Frank AO, Kessler H.

Nature. 2008 Apr 17;452(7189):822-3. doi: 10.1038/452822a. No abstract available.

PMID:
18421340
38.

Phosphorus NMR spectroscopy as a versatile tool for compound library screening.

Manzenrieder F, Frank AO, Kessler H.

Angew Chem Int Ed Engl. 2008;47(14):2608-11. doi: 10.1002/anie.200705256. No abstract available.

PMID:
18311739
39.

3-D pain drawings-mobile data collection using a PDA.

Ghinea G, Spyridonis F, Serif T, Frank AO.

IEEE Trans Inf Technol Biomed. 2008 Jan;12(1):27-33. doi: 10.1109/TITB.2007.903266.

PMID:
18270034
40.

Visualization of back pain data--a 3-D solution.

Ghinea G, Kent S, Frank AO, Chana GS.

IEEE Trans Inf Technol Biomed. 2007 Sep;11(5):595-7.

PMID:
17912977
41.

Young people's experiences using electric powered indoor - outdoor wheelchairs (EPIOCs): potential for enhancing users' development?

Evans S, Neophytou C, de Souza L, Frank AO.

Disabil Rehabil. 2007 Aug 30;29(16):1281-94.

PMID:
17654003
42.

Experiences of living with chronic back pain: the physical disabilities.

De Souza LH, Frank AO.

Disabil Rehabil. 2007 Apr 15;29(7):587-96.

PMID:
17453979
43.

Synthesis and biological evaluation of phosphino dipeptide isostere inhibitor of human beta-secretase (BACE1).

Manzenrieder F, Frank AO, Huber T, Dorner-Ciossek C, Kessler H.

Bioorg Med Chem. 2007 Jun 15;15(12):4136-43. Epub 2007 Mar 30.

PMID:
17433698
44.

Older adults' use of, and satisfaction with, electric powered indoor/outdoor wheelchairs.

Evans S, Frank AO, Neophytou C, de Souza L.

Age Ageing. 2007 Jul;36(4):431-5. Epub 2007 Mar 24.

PMID:
17384418
45.

Traumatised refugees: refugee status--a yellow flag in managing back pain.

Frank AO.

BMJ. 2007 Jan 13;334(7584):58. No abstract available.

46.

Rehabilitation: an integral part of clinical practice.

Frank AO, Chamberlain MA.

Occup Med (Lond). 2006 Aug;56(5):289-91. No abstract available.

PMID:
16868122
47.

Blood flow in stented arteries: a parametric comparison of strut design patterns in three dimensions.

He Y, Duraiswamy N, Frank AO, Moore JE Jr.

J Biomech Eng. 2005 Aug;127(4):637-47.

PMID:
16121534
48.
49.

What is intermediate care? A flawed substitute for rehabilitation in the United Kingdom.

Frank AO.

BMJ. 2004 Sep 18;329(7467):686. No abstract available.

50.

Work and the musculoskeletal conditions.

Frank AO, Maddison PJ.

Clin Med (Lond). 2004 Jul-Aug;4(4):362-5. No abstract available.

PMID:
15372898

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