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Items: 17

1.

NTRK1 is a positive regulator of YAP oncogenic function.

Yang X, Shen H, Buckley B, Chen Y, Yang N, Mussell AL, Chernov M, Kobzik L, Frangou C, Han SX, Zhang J.

Oncogene. 2019 Apr;38(15):2778-2787. doi: 10.1038/s41388-018-0609-1. Epub 2018 Dec 12.

PMID:
30542115
2.

Targeting TAZ-Driven Human Breast Cancer by Inhibiting a SKP2-p27 Signaling Axis.

Shen H, Yang N, Truskinovsky A, Chen Y, Mussell AL, Nowak NJ, Kobzik L, Frangou C, Zhang J.

Mol Cancer Res. 2019 Jan;17(1):250-262. doi: 10.1158/1541-7786.MCR-18-0332. Epub 2018 Sep 20.

PMID:
30237296
3.

Loss of KIBRA function activates EGFR signaling by inducing AREG.

Mussell AL, Denson KE, Shen H, Chen Y, Yang N, Frangou C, Zhang J.

Oncotarget. 2018 Jul 6;9(52):29975-29984. doi: 10.18632/oncotarget.25724. eCollection 2018 Jul 6.

4.

The Hippo Signaling Transducer TAZ Regulates Mammary Gland Morphogenesis and Carcinogen-induced Mammary Tumorigenesis.

Denson KE, Mussell AL, Shen H, Truskinovsky A, Yang N, Parashurama N, Chen Y, Frangou C, Yang F, Zhang J.

Sci Rep. 2018 Apr 24;8(1):6449. doi: 10.1038/s41598-018-24712-5.

5.

TRAIN (Transcription of Repeats Activates INterferon) in response to chromatin destabilization induced by small molecules in mammalian cells.

Leonova K, Safina A, Nesher E, Sandlesh P, Pratt R, Burkhart C, Lipchick B, Gitlin I, Frangou C, Koman I, Wang J, Kirsanov K, Yakubovskaya MG, Gudkov AV, Gurova K.

Elife. 2018 Feb 5;7. pii: e30842. doi: 10.7554/eLife.30842.

6.

VGLL4 Selectively Represses YAP-Dependent Gene Induction and Tumorigenic Phenotypes in Breast Cancer.

Zhang Y, Shen H, Withers HG, Yang N, Denson KE, Mussell AL, Truskinovsky A, Fan Q, Gelman IH, Frangou C, Zhang J.

Sci Rep. 2017 Jul 21;7(1):6190. doi: 10.1038/s41598-017-06227-7.

7.

Phosphorylation of Tyr188 in the WW domain of YAP1 plays an essential role in YAP1-induced cellular transformation.

Li YW, Guo J, Shen H, Li J, Yang N, Frangou C, Wilson KE, Zhang Y, Mussell AL, Sudol M, Farooq A, Qu J, Zhang J.

Cell Cycle. 2016 Sep 16;15(18):2497-505. doi: 10.1080/15384101.2016.1207836. Epub 2016 Jul 18.

8.

Functional genetics-directed identification of novel pharmacological inhibitors of FAS- and TNF-dependent apoptosis that protect mice from acute liver failure.

Komarov AP, Komarova EA, Green K, Novototskaya LR, Baker PS, Eroshkin A, Osterman AL, Chenchick AA, Frangou C, Gudkov AV.

Cell Death Dis. 2016 Mar 17;7:e2145. doi: 10.1038/cddis.2016.45.

9.

Sox4 Expression Confers Bladder Cancer Stem Cell Properties and Predicts for Poor Patient Outcome.

Shen H, Blijlevens M, Yang N, Frangou C, Wilson KE, Xu B, Zhang Y, Zhang L, Morrison CD, Shepherd L, Hu Q, Zhu Q, Wang J, Liu S, Zhang J.

Int J Biol Sci. 2015 Nov 1;11(12):1363-75. doi: 10.7150/ijbs.13240. eCollection 2015.

10.

Characterization of TAZ domains important for the induction of breast cancer stem cell properties and tumorigenesis.

Li YW, Shen H, Frangou C, Yang N, Guo J, Xu B, Bshara W, Shepherd L, Zhu Q, Wang J, Hu Q, Liu S, Morrison CD, Sun P, Zhang J.

Cell Cycle. 2015;14(1):146-56. doi: 10.4161/15384101.2014.967106.

11.

Molecular profiling and computational network analysis of TAZ-mediated mammary tumorigenesis identifies actionable therapeutic targets.

Frangou C, Li YW, Shen H, Yang N, Wilson KE, Blijlevens M, Guo J, Nowak NJ, Zhang J.

Oncotarget. 2014 Dec 15;5(23):12166-76.

12.

6p22.3 amplification as a biomarker and potential therapeutic target of advanced stage bladder cancer.

Shen H, Morrison CD, Zhang J, Underwood W 3rd, Yang N, Frangou C, Eng K, Head K, Bollag RJ, Kavuri SK, Rojiani AM, Li Y, Yan L, Hill A, Woloszynska-Read A, Wang J, Liu S, Trump DL, Candace JS.

Oncotarget. 2013 Nov;4(11):2124-34.

13.

Vascular priming enhances chemotherapeutic efficacy against head and neck cancer.

Folaron M, Kalmuk J, Lockwood J, Frangou C, Vokes J, Turowski SG, Merzianu M, Rigual NR, Sullivan-Nasca M, Kuriakose MA, Hicks WL Jr, Singh AK, Seshadri M.

Oral Oncol. 2013 Sep;49(9):893-902. doi: 10.1016/j.oraloncology.2013.06.011. Epub 2013 Jul 23.

14.

Bivalent domains enforce transcriptional memory of DNA methylated genes in cancer cells.

Rodriguez J, Muñoz M, Vives L, Frangou CG, Groudine M, Peinado MA.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19809-14. doi: 10.1073/pnas.0810133105. Epub 2008 Dec 5.

15.

How does leflunomide modulate the immune response in rheumatoid arthritis?

Fox RI, Herrmann ML, Frangou CG, Wahl GM, Morris RE, Kirschbaum BJ.

BioDrugs. 1999 Oct;12(4):301-15.

PMID:
18031184
16.

PRAK is essential for ras-induced senescence and tumor suppression.

Sun P, Yoshizuka N, New L, Moser BA, Li Y, Liao R, Xie C, Chen J, Deng Q, Yamout M, Dong MQ, Frangou CG, Yates JR 3rd, Wright PE, Han J.

Cell. 2007 Jan 26;128(2):295-308.

17.

Mechanism of action for leflunomide in rheumatoid arthritis.

Fox RI, Herrmann ML, Frangou CG, Wahl GM, Morris RE, Strand V, Kirschbaum BJ.

Clin Immunol. 1999 Dec;93(3):198-208. Review.

PMID:
10600330

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