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Items: 42


Akt and STAT5 mediate naïve human CD4+ T-cell early metabolic response to TCR stimulation.

Jones N, Vincent EE, Cronin JG, Panetti S, Chambers M, Holm SR, Owens SE, Francis NJ, Finlay DK, Thornton CA.

Nat Commun. 2019 May 3;10(1):2042. doi: 10.1038/s41467-019-10023-4.


Antibiotic Prescribing Rate in Lebanese Community Pharmacies: A Nationwide Patient-Simulated Study of Acute Bacterial Rhinosinusitis.

Yaacoub SG, Lahoud NA, Francis NJ, Rahme DW, Murr TH, Maison PF, Saleh NG.

J Epidemiol Glob Health. 2019 Mar;9(1):44-49. doi: 10.2991/jegh.k.190305.001.


Metabolic Adaptation of Human CD4+ and CD8+ T-Cells to T-Cell Receptor-Mediated Stimulation.

Jones N, Cronin JG, Dolton G, Panetti S, Schauenburg AJ, Galloway SAE, Sewell AK, Cole DK, Thornton CA, Francis NJ.

Front Immunol. 2017 Nov 9;8:1516. doi: 10.3389/fimmu.2017.01516. eCollection 2017.


Inheritance of Histones H3 and H4 during DNA Replication In Vitro.

Madamba EV, Berthet EB, Francis NJ.

Cell Rep. 2017 Oct 31;21(5):1361-1374. doi: 10.1016/j.celrep.2017.10.033.


Chromatin: Polycomb Group SAMs Unite.

Kim CA, Francis NJ.

Curr Biol. 2016 Aug 8;26(15):R710-R712. doi: 10.1016/j.cub.2016.06.001.


Chromatin topology is coupled to Polycomb group protein subnuclear organization.

Wani AH, Boettiger AN, Schorderet P, Ergun A, Münger C, Sadreyev RI, Zhuang X, Kingston RE, Francis NJ.

Nat Commun. 2016 Jan 13;7:10291. doi: 10.1038/ncomms10291.


Bioenergetic analysis of human peripheral blood mononuclear cells.

Jones N, Piasecka J, Bryant AH, Jones RH, Skibinski DO, Francis NJ, Thornton CA.

Clin Exp Immunol. 2015 Oct;182(1):69-80. doi: 10.1111/cei.12662. Epub 2015 Jul 24.


Contributions to drug resistance in glioblastoma derived from malignant cells in the sub-ependymal zone.

Piccirillo SG, Spiteri I, Sottoriva A, Touloumis A, Ber S, Price SJ, Heywood R, Francis NJ, Howarth KD, Collins VP, Venkitaraman AR, Curtis C, Marioni JC, Tavaré S, Watts C.

Cancer Res. 2015 Jan 1;75(1):194-202. doi: 10.1158/0008-5472.CAN-13-3131. Epub 2014 Nov 18.


A polycomb group protein is retained at specific sites on chromatin in mitosis.

Follmer NE, Wani AH, Francis NJ.

PLoS Genet. 2012;8(12):e1003135. doi: 10.1371/journal.pgen.1003135. Epub 2012 Dec 20.


Chromatin modification by PSC occurs at one PSC per nucleosome and does not require the acidic patch of histone H2A.

Lo SM, McElroy KA, Francis NJ.

PLoS One. 2012;7(10):e47162. doi: 10.1371/journal.pone.0047162. Epub 2012 Oct 11.


A Polycomb complex remains bound through DNA replication in the absence of other eukaryotic proteins.

Lengsfeld BM, Berry KN, Ghosh S, Takahashi M, Francis NJ.

Sci Rep. 2012;2:661. Epub 2012 Sep 17.


Small-molecule inhibitors of the protein methyltransferase SET7/9 identified in a high-throughput screen.

Francis NJ, Rowlands M, Workman P, Jones K, Aherne W.

J Biomol Screen. 2012 Sep;17(8):1102-9. doi: 10.1177/1087057112452137. Epub 2012 Jul 5.


A bridging model for persistence of a polycomb group protein complex through DNA replication in vitro.

Lo SM, Follmer NE, Lengsfeld BM, Madamba EV, Seong S, Grau DJ, Francis NJ.

Mol Cell. 2012 Jun 29;46(6):784-96. doi: 10.1016/j.molcel.2012.05.038.


A core subunit of Polycomb repressive complex 1 is broadly conserved in function but not primary sequence.

Beh LY, Colwell LJ, Francis NJ.

Proc Natl Acad Sci U S A. 2012 May 1;109(18):E1063-71. doi: 10.1073/pnas.1118678109. Epub 2012 Apr 18.


Bipaddled submental artery flap.

Ramkumar A, Francis NJ, Senthil Kumar R, Dinesh Kumar S.

Int J Oral Maxillofac Surg. 2012 Apr;41(4):458-60. doi: 10.1016/j.ijom.2011.12.030. Epub 2012 Jan 18.


Validation of the Revised Physical Therapist Clinical Performance Instrument (PT CPI): Version 2006.

Roach KE, Frost JS, Francis NJ, Giles S, Nordrum JT, Delitto A.

Phys Ther. 2012 Mar;92(3):416-28. doi: 10.2522/ptj.20110129. Epub 2011 Dec 1.


Speed reading for genes: bookmarks set the pace.

Follmer NE, Francis NJ.

Dev Cell. 2011 Nov 15;21(5):807-8. doi: 10.1016/j.devcel.2011.10.020.


A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome.

Francis NJ, McNicholas B, Awan A, Waldron M, Reddan D, Sadlier D, Kavanagh D, Strain L, Marchbank KJ, Harris CL, Goodship TH.

Blood. 2012 Jan 12;119(2):591-601. doi: 10.1182/blood-2011-03-339903. Epub 2011 Nov 4.


Compaction of chromatin by diverse Polycomb group proteins requires localized regions of high charge.

Grau DJ, Chapman BA, Garlick JD, Borowsky M, Francis NJ, Kingston RE.

Genes Dev. 2011 Oct 15;25(20):2210-21. doi: 10.1101/gad.17288211.


Gene regulation: implications of histone dispersal patterns for epigenetics.

Francis NJ.

Curr Biol. 2011 Sep 13;21(17):R659-61. doi: 10.1016/j.cub.2011.06.062.


Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk.

Heurich M, Martínez-Barricarte R, Francis NJ, Roberts DL, Rodríguez de Córdoba S, Morgan BP, Harris CL.

Proc Natl Acad Sci U S A. 2011 May 24;108(21):8761-6. doi: 10.1073/pnas.1019338108. Epub 2011 May 9.


Rectovaginal fistula in ovarian cancer.

Ramkumar A, Mahalingam S, Francis NJ.

Int J Gynaecol Obstet. 2011 May;113(2):155-6. doi: 10.1016/j.ijgo.2010.12.010. Epub 2011 Mar 21. No abstract available.


Mechanisms of epigenetic inheritance: copying of polycomb repressed chromatin.

Francis NJ.

Cell Cycle. 2009 Nov 1;8(21):3521-6. Epub 2009 Nov 21. Review.


Does maintenance of polycomb group proteins through DNA replication contribute to epigenetic inheritance?

Francis NJ.

Epigenetics. 2009 Aug 16;4(6):370-3. Epub 2009 Aug 26. Review.


Polycomb proteins remain bound to chromatin and DNA during DNA replication in vitro.

Francis NJ, Follmer NE, Simon MD, Aghia G, Butler JD.

Cell. 2009 Apr 3;137(1):110-22. doi: 10.1016/j.cell.2009.02.017. Epub 2009 Mar 19.


Polycomb group protein Suppressor 2 of zeste is a functional homolog of Posterior Sex Combs.

Lo SM, Ahuja NK, Francis NJ.

Mol Cell Biol. 2009 Jan;29(2):515-25. doi: 10.1128/MCB.01044-08. Epub 2008 Nov 3.


Epigenomics: a roadmap, but to where?

Madhani HD, Francis NJ, Kingston RE, Kornberg RD, Moazed D, Narlikar GJ, Panning B, Struhl K.

Science. 2008 Oct 3;322(5898):43-4. doi: 10.1126/science.322.5898.43b. No abstract available.


Analysis of a polycomb group protein defines regions that link repressive activity on nucleosomal templates to in vivo function.

King IF, Emmons RB, Francis NJ, Wild B, Müller J, Kingston RE, Wu CT.

Mol Cell Biol. 2005 Aug;25(15):6578-91.


WWOX mRNA expression profile in epithelial ovarian cancer supports the role of WWOX variant 1 as a tumour suppressor, although the role of variant 4 remains unclear.

Gourley C, Paige AJW, Taylor KJ, Scott D, Francis NJ, Rush R, Aldaz CM, Smyth JF, Gabra H.

Int J Oncol. 2005 Jun;26(6):1681-1689.


Chromatin compaction by a polycomb group protein complex.

Francis NJ, Kingston RE, Woodcock CL.

Science. 2004 Nov 26;306(5701):1574-7.


Requirement for sex comb on midleg protein interactions in Drosophila polycomb group repression.

Peterson AJ, Mallin DR, Francis NJ, Ketel CS, Stamm J, Voeller RK, Kingston RE, Simon JA.

Genetics. 2004 Jul;167(3):1225-39.


Propagation of silencing; recruitment and repression of naive chromatin in trans by polycomb repressed chromatin.

Lavigne M, Francis NJ, King IF, Kingston RE.

Mol Cell. 2004 Feb 13;13(3):415-25.


Histone methyltransferase activity of a Drosophila Polycomb group repressor complex.

Müller J, Hart CM, Francis NJ, Vargas ML, Sengupta A, Wild B, Miller EL, O'Connor MB, Kingston RE, Simon JA.

Cell. 2002 Oct 18;111(2):197-208.


Reconstitution of a functional core polycomb repressive complex.

Francis NJ, Saurin AJ, Shao Z, Kingston RE.

Mol Cell. 2001 Sep;8(3):545-56.


Mechanisms of transcriptional memory.

Francis NJ, Kingston RE.

Nat Rev Mol Cell Biol. 2001 Jun;2(6):409-21. Review.


Cellular and molecular determinants of sympathetic neuron development.

Francis NJ, Landis SC.

Annu Rev Neurosci. 1999;22:541-66. Review.


A sweat gland-derived differentiation activity acts through known cytokine signaling pathways.

Habecker BA, Symes AJ, Stahl N, Francis NJ, Economides A, Fink JS, Yancopoulos GD, Landis SC.

J Biol Chem. 1997 Nov 28;272(48):30421-8.


The role of acetylcholine in regulating secretory responsiveness in rat sweat glands.

Grant MP, Francis NJ, Landis SC.

Mol Cell Neurosci. 1995 Feb;6(1):32-42.


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