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Items: 1 to 50 of 152

1.

Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on calcium.

Liu G, Thangavel R, Rysted J, Kim Y, Francis MB, Adams E, Lin Z, Taugher RJ, Wemmie JA, Usachev YM, Lee G.

J Neurosci Res. 2019 Nov;97(11):1393-1413. doi: 10.1002/jnr.24517. Epub 2019 Aug 26.

PMID:
31452242
2.

Site-Selective Protein Immobilization on Polymeric Supports through N-Terminal Imidazolidinone Formation.

Koo B, Dolan NS, Wucherer K, Munch HK, Francis MB.

Biomacromolecules. 2019 Sep 9. doi: 10.1021/acs.biomac.9b01002. [Epub ahead of print]

PMID:
31448594
3.

A thylakoid membrane-bound and redox-active rubredoxin (RBD1) functions in de novo assembly and repair of photosystem II.

García-Cerdán JG, Furst AL, McDonald KL, Schünemann D, Francis MB, Niyogi KK.

Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16631-16640. doi: 10.1073/pnas.1903314116. Epub 2019 Jul 29.

4.

Tau interacts with SHP2 in neuronal systems and in Alzheimer's disease brains.

Kim Y, Liu G, Leugers CJ, Mueller JD, Francis MB, Hefti MM, Schneider JA, Lee G.

J Cell Sci. 2019 Jul 15;132(14). pii: jcs229054. doi: 10.1242/jcs.229054.

PMID:
31201283
5.

Rotaxane Probes for the Detection of Hydrogen Peroxide by 129 Xe HyperCEST NMR Spectroscopy.

Klass SH, Truxal AE, Fiala TA, Kelly J, Nguyen D, Finbloom JA, Wemmer DE, Pines A, Francis MB.

Angew Chem Int Ed Engl. 2019 Jul 15;58(29):9948-9953. doi: 10.1002/anie.201903045. Epub 2019 Jun 11.

PMID:
31004389
6.

Role of the global regulator Rex in control of NAD+ -regeneration in Clostridioides (Clostridium) difficile.

Bouillaut L, Dubois T, Francis MB, Daou N, Monot M, Sorg JA, Sonenshein AL, Dupuy B.

Mol Microbiol. 2019 Jun;111(6):1671-1688. doi: 10.1111/mmi.14245. Epub 2019 Apr 2.

PMID:
30882947
7.

Self-Assembling Micelles Based on an Intrinsically Disordered Protein Domain.

Klass SH, Smith MJ, Fiala TA, Lee JP, Omole AO, Han BG, Downing KH, Kumar S, Francis MB.

J Am Chem Soc. 2019 Mar 13;141(10):4291-4299. doi: 10.1021/jacs.8b10688. Epub 2019 Feb 26.

PMID:
30739445
8.

Systematic Engineering of a Protein Nanocage for High-Yield, Site-Specific Modification.

Brauer DD, Hartman EC, Bader DLV, Merz ZN, Tullman-Ercek D, Francis MB.

J Am Chem Soc. 2019 Mar 6;141(9):3875-3884. doi: 10.1021/jacs.8b10734. Epub 2019 Feb 20.

PMID:
30730722
9.

Enzymatic Modification of N-Terminal Proline Residues Using Phenol Derivatives.

Maza JC, Bader DLV, Xiao L, Marmelstein AM, Brauer DD, ElSohly AM, Smith MJ, Krska SW, Parish CA, Francis MB.

J Am Chem Soc. 2019 Mar 6;141(9):3885-3892. doi: 10.1021/jacs.8b10845. Epub 2019 Feb 20.

PMID:
30726077
10.

Cytosolic Delivery of Proteins Using Amphiphilic Polymers with 2-Pyridinecarboxaldehyde Groups for Site-Selective Attachment.

Sangsuwan R, Tachachartvanich P, Francis MB.

J Am Chem Soc. 2019 Feb 13;141(6):2376-2383. doi: 10.1021/jacs.8b10947. Epub 2019 Feb 5.

PMID:
30663873
11.

Evaluation of Three Morphologically Distinct Virus-Like Particles as Nanocarriers for Convection-Enhanced Drug Delivery to Glioblastoma.

Finbloom JA, Aanei IL, Bernard JM, Klass SH, Elledge SK, Han K, Ozawa T, Nicolaides TP, Berger MS, Francis MB.

Nanomaterials (Basel). 2018 Dec 5;8(12). pii: E1007. doi: 10.3390/nano8121007.

12.

Impedance-Based Detection of Bacteria.

Furst AL, Francis MB.

Chem Rev. 2019 Jan 9;119(1):700-726. doi: 10.1021/acs.chemrev.8b00381. Epub 2018 Dec 17.

PMID:
30557008
13.

Mechanisms Underlying Microbial-Mediated Changes in Social Behavior in Mouse Models of Autism Spectrum Disorder.

Sgritta M, Dooling SW, Buffington SA, Momin EN, Francis MB, Britton RA, Costa-Mattioli M.

Neuron. 2019 Jan 16;101(2):246-259.e6. doi: 10.1016/j.neuron.2018.11.018. Epub 2018 Dec 3.

PMID:
30522820
14.

Effects of Conformational Changes in Peptide-CRM197 Conjugate Vaccines.

Jaffe J, Wucherer K, Sperry J, Zou Q, Chang Q, Massa MA, Bhattacharya K, Kumar S, Caparon M, Stead D, Wright P, Dirksen A, Francis MB.

Bioconjug Chem. 2019 Jan 16;30(1):47-53. doi: 10.1021/acs.bioconjchem.8b00661. Epub 2018 Dec 12.

PMID:
30475601
15.

Molecular Mechanics Simulations and Improved Tight-Binding Hamiltonians for Artificial Light Harvesting Systems: Predicting Geometric Distributions, Disorder, and Spectroscopy of Chromophores in a Protein Environment.

Lee J, Lee D, Kocherzhenko AA, Greenman L, Finley DT, Francis MB, Whaley KB.

J Phys Chem B. 2018 Dec 27;122(51):12292-12301. doi: 10.1021/acs.jpcb.8b08858. Epub 2018 Dec 17.

PMID:
30458617
16.

Experimental Evaluation of Coevolution in a Self-Assembling Particle.

Hartman EC, Lobba MJ, Favor AH, Robinson SA, Francis MB, Tullman-Ercek D.

Biochemistry. 2019 Mar 19;58(11):1527-1538. doi: 10.1021/acs.biochem.8b00948. Epub 2018 Dec 6.

PMID:
30418759
17.

DNA Hybridization to Control Cellular Interactions.

Furst AL, Klass SH, Francis MB.

Trends Biochem Sci. 2019 Apr;44(4):342-350. doi: 10.1016/j.tibs.2018.10.002. Epub 2018 Nov 6. Review.

PMID:
30413353
18.

DNA Hybridization To Interface Current-Producing Cells with Electrode Surfaces.

Furst AL, Smith MJ, Lee MC, Francis MB.

ACS Cent Sci. 2018 Jul 25;4(7):880-884. doi: 10.1021/acscentsci.8b00255. Epub 2018 Jul 2.

19.

Vascular Cell Adhesion Molecule-Targeted MS2 Viral Capsids for the Detection of Early-Stage Atherosclerotic Plaques.

Aanei IL, Huynh T, Seo Y, Francis MB.

Bioconjug Chem. 2018 Aug 15;29(8):2526-2530. doi: 10.1021/acs.bioconjchem.8b00453. Epub 2018 Aug 2.

PMID:
30059611
20.

Supramolecular strategies for protein immobilization and modification.

Finbloom JA, Francis MB.

Curr Opin Chem Biol. 2018 Oct;46:91-98. doi: 10.1016/j.cbpa.2018.05.023. Epub 2018 Jul 21. Review.

PMID:
30041103
21.

Dual Surface Modification of Genome-Free MS2 Capsids for Delivery Applications.

Aanei IL, Francis MB.

Methods Mol Biol. 2018;1776:629-642. doi: 10.1007/978-1-4939-7808-3_40.

PMID:
29869270
22.

Encapsulation of Negatively Charged Cargo in MS2 Viral Capsids.

Aanei IL, Glasgow JE, Capehart SL, Francis MB.

Methods Mol Biol. 2018;1776:303-317. doi: 10.1007/978-1-4939-7808-3_21.

PMID:
29869251
23.

Antibody Modification of p-Aminophenylalanine-Containing Proteins.

ElSohly AM, Netirojjanakul C, Francis MB.

Methods Mol Biol. 2018;1798:195-201. doi: 10.1007/978-1-4939-7893-9_15.

PMID:
29868961
24.

New Techniques for the Generation and Analysis of Tailored Microbial Systems on Surfaces.

Furst AL, Smith MJ, Francis MB.

Biochemistry. 2018 May 29;57(21):3017-3026. doi: 10.1021/acs.biochem.8b00324. Epub 2018 May 17.

PMID:
29771497
25.

Methods for Generating Microbial Cocultures that Grow in the Absence of Fixed Carbon or Nitrogen.

Smith MJ, Francis MB.

Methods Mol Biol. 2018;1772:45-60. doi: 10.1007/978-1-4939-7795-6_3.

PMID:
29754222
26.

Exploiting Chromophore-Protein Interactions through Linker Engineering To Tune Photoinduced Dynamics in a Biomimetic Light-Harvesting Platform.

Delor M, Dai J, Roberts TD, Rogers JR, Hamed SM, Neaton JB, Geissler PL, Francis MB, Ginsberg NS.

J Am Chem Soc. 2018 May 23;140(20):6278-6287. doi: 10.1021/jacs.7b13598. Epub 2018 May 9.

PMID:
29741876
27.

Quantitative characterization of all single amino acid variants of a viral capsid-based drug delivery vehicle.

Hartman EC, Jakobson CM, Favor AH, Lobba MJ, Álvarez-Benedicto E, Francis MB, Tullman-Ercek D.

Nat Commun. 2018 Apr 11;9(1):1385. doi: 10.1038/s41467-018-03783-y.

28.

Structural Regulation of a Neurofilament-Inspired Intrinsically Disordered Protein Brush by Multisite Phosphorylation.

Lei R, Lee JP, Francis MB, Kumar S.

Biochemistry. 2018 Jul 10;57(27):4019-4028. doi: 10.1021/acs.biochem.8b00007. Epub 2018 Apr 6.

PMID:
29557644
29.

Direct Electrochemical Bioconjugation on Metal Surfaces.

Furst AL, Smith MJ, Francis MB.

J Am Chem Soc. 2017 Sep 13;139(36):12610-12616. doi: 10.1021/jacs.7b06385. Epub 2017 Aug 31.

PMID:
28858482
30.

Cucurbit[6]uril-Promoted Click Chemistry for Protein Modification.

Finbloom JA, Han K, Slack CC, Furst AL, Francis MB.

J Am Chem Soc. 2017 Jul 19;139(28):9691-9697. doi: 10.1021/jacs.7b05164. Epub 2017 Jul 7.

PMID:
28650616
31.

Targeting the N terminus for site-selective protein modification.

Rosen CB, Francis MB.

Nat Chem Biol. 2017 Jul;13(7):697-705. doi: 10.1038/nchembio.2416. Epub 2017 Jun 20. Review.

PMID:
28632705
32.

Quantifying Hormone Disruptors with an Engineered Bacterial Biosensor.

Furst AL, Hoepker AC, Francis MB.

ACS Cent Sci. 2017 Feb 22;3(2):110-116. doi: 10.1021/acscentsci.6b00322. Epub 2017 Jan 11.

33.

A modular platform to develop peptoid-based selective fluorescent metal sensors.

Knight AS, Kulkarni RU, Zhou EY, Franke JM, Miller EW, Francis MB.

Chem Commun (Camb). 2017 Mar 25;53(24):3477-3480. doi: 10.1039/c7cc00931c. Epub 2017 Mar 8.

34.

ortho-Methoxyphenols as Convenient Oxidative Bioconjugation Reagents with Application to Site-Selective Heterobifunctional Cross-Linkers.

ElSohly AM, MacDonald JI, Hentzen NB, Aanei IL, El Muslemany KM, Francis MB.

J Am Chem Soc. 2017 Mar 15;139(10):3767-3773. doi: 10.1021/jacs.6b12966. Epub 2017 Mar 2.

PMID:
28207247
35.

Rotaxane probes for protease detection by 129Xe hyperCEST NMR.

Slack CC, Finbloom JA, Jeong K, Bruns CJ, Wemmer DE, Pines A, Francis MB.

Chem Commun (Camb). 2017 Jan 17;53(6):1076-1079. doi: 10.1039/c6cc09302g.

36.

Site-Selective Oxidative Coupling Reactions for the Attachment of Enzymes to Glass Surfaces through DNA-Directed Immobilization.

Palla KS, Hurlburt TJ, Buyanin AM, Somorjai GA, Francis MB.

J Am Chem Soc. 2017 Feb 8;139(5):1967-1974. doi: 10.1021/jacs.6b11716. Epub 2017 Jan 24.

PMID:
28001056
37.

Dipicolinic Acid Release by Germinating Clostridium difficile Spores Occurs through a Mechanosensing Mechanism.

Francis MB, Sorg JA.

mSphere. 2016 Dec 14;1(6). pii: e00306-16. eCollection 2016 Nov-Dec.

38.

Improving metabolite production in microbial co-cultures using a spatially constrained hydrogel.

Smith MJ, Francis MB.

Biotechnol Bioeng. 2017 Jun;114(6):1195-1200. doi: 10.1002/bit.26235. Epub 2017 Jan 25.

PMID:
27943258
39.

Near-Quantitative Aqueous Synthesis of Rotaxanes via Bioconjugation to Oligopeptides and Proteins.

Bruns CJ, Liu H, Francis MB.

J Am Chem Soc. 2016 Nov 30;138(47):15307-15310. Epub 2016 Nov 17.

PMID:
27933926
40.

Stable Disk Assemblies of a Tobacco Mosaic Virus Mutant as Nanoscale Scaffolds for Applications in Drug Delivery.

Finbloom JA, Han K, Aanei IL, Hartman EC, Finley DT, Dedeo MT, Fishman M, Downing KH, Francis MB.

Bioconjug Chem. 2016 Oct 19;27(10):2480-2485. doi: 10.1021/acs.bioconjchem.6b00424. Epub 2016 Oct 7.

PMID:
27712069
41.

Biodistribution of Antibody-MS2 Viral Capsid Conjugates in Breast Cancer Models.

Aanei IL, ElSohly AM, Farkas ME, Netirojjanakul C, Regan M, Taylor Murphy S, O'Neil JP, Seo Y, Francis MB.

Mol Pharm. 2016 Nov 7;13(11):3764-3772. Epub 2016 Sep 30.

42.

Obesity alters immune and metabolic profiles: New insight from obese-resistant mice on high-fat diet.

Boi SK, Buchta CM, Pearson NA, Francis MB, Meyerholz DK, Grobe JL, Norian LA.

Obesity (Silver Spring). 2016 Oct;24(10):2140-9. doi: 10.1002/oby.21620. Epub 2016 Aug 12.

43.

(129)Xe NMR Relaxation-Based Macromolecular Sensing.

Gomes MD, Dao P, Jeong K, Slack CC, Vassiliou CC, Finbloom JA, Francis MB, Wemmer DE, Pines A.

J Am Chem Soc. 2016 Aug 10;138(31):9747-50. doi: 10.1021/jacs.6b02758. Epub 2016 Jul 29.

PMID:
27472048
44.

Targeted Molecular Imaging of Cancer Cells Using MS2-Based (129)Xe NMR.

Jeong K, Netirojjanakul C, Munch HK, Sun J, Finbloom JA, Wemmer DE, Pines A, Francis MB.

Bioconjug Chem. 2016 Aug 17;27(8):1796-801. doi: 10.1021/acs.bioconjchem.6b00275. Epub 2016 Aug 1.

PMID:
27454679
45.

Direct detection of nitrotyrosine-containing proteins using an aniline-based oxidative coupling strategy.

Sangsuwan R, Obermeyer AC, Tachachartvanich P, Palaniappan KK, Francis MB.

Chem Commun (Camb). 2016 Aug 21;52(65):10036-9. doi: 10.1039/c6cc04575h. Epub 2016 Jul 22.

46.

Detecting Cortex Fragments During Bacterial Spore Germination.

Francis MB, Sorg JA.

J Vis Exp. 2016 Jun 25;(112). doi: 10.3791/54146.

47.

N-terminal specific conjugation of extracellular matrix proteins to 2-pyridinecarboxaldehyde functionalized polyacrylamide hydrogels.

Lee JP, Kassianidou E, MacDonald JI, Francis MB, Kumar S.

Biomaterials. 2016 Sep;102:268-76. doi: 10.1016/j.biomaterials.2016.06.022. Epub 2016 Jun 15.

48.

Capture and Recycling of Sortase A through Site-Specific Labeling with Lithocholic Acid.

Rosen CB, Kwant RL, MacDonald JI, Rao M, Francis MB.

Angew Chem Int Ed Engl. 2016 Jul 18;55(30):8585-9. doi: 10.1002/anie.201602353. Epub 2016 May 30.

PMID:
27239057
49.

A Designed A. vinelandii-S. elongatus Coculture for Chemical Photoproduction from Air, Water, Phosphate, and Trace Metals.

Smith MJ, Francis MB.

ACS Synth Biol. 2016 Sep 16;5(9):955-61. doi: 10.1021/acssynbio.6b00107. Epub 2016 Jun 6.

PMID:
27232890
50.

Development of Peptoid-Based Ligands for the Removal of Cadmium from Biological Media.

Knight AS, Zhou EY, Francis MB.

Chem Sci. 2015 Jul 1;7(6):4042-4048. Epub 2015 May 14.

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