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Items: 9

1.

Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics.

Li X, Francies HE, Secrier M, Perner J, Miremadi A, Galeano-Dalmau N, Barendt WJ, Letchford L, Leyden GM, Goffin EK, Barthorpe A, Lightfoot H, Chen E, Gilbert J, Noorani A, Devonshire G, Bower L, Grantham A, MacRae S, Grehan N, Wedge DC, Fitzgerald RC, Garnett MJ.

Nat Commun. 2018 Jul 30;9(1):2983. doi: 10.1038/s41467-018-05190-9.

2.

Erratum to: Drug Sensitivity Assays of Human Cancer Organoid Cultures.

Francies HE, Barthorpe A, McLaren-Douglas A, Barendt WJ, Garnett MJ.

Methods Mol Biol. 2018 Mar 27. doi: 10.1007/7651_2018_138. [Epub ahead of print] No abstract available.

PMID:
30006863
3.

Itraconazole targets cell cycle heterogeneity in colorectal cancer.

Buczacki SJA, Popova S, Biggs E, Koukorava C, Buzzelli J, Vermeulen L, Hazelwood L, Francies H, Garnett MJ, Winton DJ.

J Exp Med. 2018 Jul 2;215(7):1891-1912. doi: 10.1084/jem.20171385. Epub 2018 May 31.

4.

Human primary liver cancer-derived organoid cultures for disease modeling and drug screening.

Broutier L, Mastrogiovanni G, Verstegen MM, Francies HE, Gavarr├│ LM, Bradshaw CR, Allen GE, Arnes-Benito R, Sidorova O, Gaspersz MP, Georgakopoulos N, Koo BK, Dietmann S, Davies SE, Praseedom RK, Lieshout R, IJzermans JNM, Wigmore SJ, Saeb-Parsy K, Garnett MJ, van der Laan LJ, Huch M.

Nat Med. 2017 Dec;23(12):1424-1435. doi: 10.1038/nm.4438. Epub 2017 Nov 13.

5.

Drug Sensitivity Assays of Human Cancer Organoid Cultures.

Francies HE, Barthorpe A, McLaren-Douglas A, Barendt WJ, Garnett MJ.

Methods Mol Biol. 2016 Sep 15. [Epub ahead of print] Erratum in: Methods Mol Biol. 2018 Mar 27;:.

PMID:
27628132
6.

What role could organoids play in the personalization of cancer treatment?

Francies HE, Garnett MJ.

Pharmacogenomics. 2015;16(14):1523-6. doi: 10.2217/pgs.15.114. Epub 2015 Oct 20.

PMID:
26485224
7.

Prospective derivation of a living organoid biobank of colorectal cancer patients.

van de Wetering M, Francies HE, Francis JM, Bounova G, Iorio F, Pronk A, van Houdt W, van Gorp J, Taylor-Weiner A, Kester L, McLaren-Douglas A, Blokker J, Jaksani S, Bartfeld S, Volckman R, van Sluis P, Li VS, Seepo S, Sekhar Pedamallu C, Cibulskis K, Carter SL, McKenna A, Lawrence MS, Lichtenstein L, Stewart C, Koster J, Versteeg R, van Oudenaarden A, Saez-Rodriguez J, Vries RG, Getz G, Wessels L, Stratton MR, McDermott U, Meyerson M, Garnett MJ, Clevers H.

Cell. 2015 May 7;161(4):933-45. doi: 10.1016/j.cell.2015.03.053.

8.

Fulvestrant-induced expression of ErbB3 and ErbB4 receptors sensitizes oestrogen receptor-positive breast cancer cells to heregulin ╬▓1.

Hutcheson IR, Goddard L, Barrow D, McClelland RA, Francies HE, Knowlden JM, Nicholson RI, Gee JM.

Breast Cancer Res. 2011 Mar 11;13(2):R29. doi: 10.1186/bcr2848.

9.

Antihormone induced compensatory signalling in breast cancer: an adverse event in the development of endocrine resistance.

Gee JM, Nicholson RI, Barrow D, Dutkowski CM, Goddard L, Jordan NJ, McClelland RA, Knowlden JM, Francies HE, Hiscox SE, Hutcheson IR.

Horm Mol Biol Clin Investig. 2011 Mar 1;5(2):67-77. doi: 10.1515/HMBCI.2011.009.

PMID:
25961242

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