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Items: 1 to 50 of 152

1.

Regulatory T Cells Restrict Permeability to Bacterial Antigen Translocation and Preserve Short-Chain Fatty Acids in Experimental Cirrhosis.

Juanola O, Piñero P, Gómez-Hurtado I, Caparrós E, García-Villalba R, Marín A, Zapater P, Tarín F, González-Navajas JM, Tomás-Barberán FA, Francés R.

Hepatol Commun. 2018 Oct 22;2(12):1610-1623. doi: 10.1002/hep4.1268. eCollection 2018 Dec.

2.

The effects of metabolic status on non-alcoholic fatty liver disease-related outcomes, beyond the presence of obesity.

Ampuero J, Aller R, Gallego-Durán R, Banales JM, Crespo J, García-Monzón C, Pareja MJ, Vilar-Gómez E, Caballería J, Escudero-García D, Gomez-Camarero J, Calleja JL, Latorre M, Albillos A, Salmeron J, Aspichueta P, Lo Iacono O, Francés R, Benlloch S, Fernández-Rodríguez C, García-Samaniego J, Estévez P, Andrade RJ, Turnes J, Romero-Gómez M; HEPAmet Registry.

Aliment Pharmacol Ther. 2018 Dec;48(11-12):1260-1270. doi: 10.1111/apt.15015. Epub 2018 Oct 23.

PMID:
30353552
3.

Effects of aging on liver microcirculatory function and sinusoidal phenotype.

Maeso-Díaz R, Ortega-Ribera M, Fernández-Iglesias A, Hide D, Muñoz L, Hessheimer AJ, Vila S, Francés R, Fondevila C, Albillos A, Peralta C, Bosch J, Tacke F, Cogger VC, Gracia-Sancho J.

Aging Cell. 2018 Dec;17(6):e12829. doi: 10.1111/acel.12829. Epub 2018 Sep 8.

4.

AIM2 deficiency reduces the development of hepatocellular carcinoma in mice.

Martínez-Cardona C, Lozano-Ruiz B, Bachiller V, Peiró G, Algaba-Chueca F, Gómez-Hurtado I, Such J, Zapater P, Francés R, González-Navajas JM.

Int J Cancer. 2018 Dec 1;143(11):2997-3007. doi: 10.1002/ijc.31827. Epub 2018 Oct 9.

PMID:
30133699
5.

MicroRNA-30c-5p modulates neuropathic pain in rodents.

Tramullas M, Francés R, de la Fuente R, Velategui S, Carcelén M, García R, Llorca J, Hurlé MA.

Sci Transl Med. 2018 Aug 8;10(453). pii: eaao6299. doi: 10.1126/scitranslmed.aao6299.

PMID:
30089634
6.

The Interleukin-20 Cytokine Family in Liver Disease.

Caparrós E, Francés R.

Front Immunol. 2018 May 28;9:1155. doi: 10.3389/fimmu.2018.01155. eCollection 2018. Review.

7.

Treatment with non-selective beta-blockers affects the systemic inflammatory response to bacterial DNA in patients with cirrhosis.

Gimenez P, Garcia-Martinez I, Francés R, Gonzalez-Navajas JM, Mauri M, Alfayate R, Almenara S, Miralles C, Palazon JM, Carnicer F, Pascual S, Such J, Horga JF, Zapater P.

Liver Int. 2018 Dec;38(12):2219-2227. doi: 10.1111/liv.13890. Epub 2018 Jun 19.

8.

Improved hemodynamic and liver function in portal hypertensive cirrhotic rats after administration of B. pseudocatenulatum CECT 7765.

Gómez-Hurtado I, Zapater P, Portune K, Juanola O, Fernández-Iglesias A, González-Navajas JM, Gracia-Sancho J, Sanz Y, Francés R.

Eur J Nutr. 2018 May 10. doi: 10.1007/s00394-018-1709-y. [Epub ahead of print]

PMID:
29748815
9.

Help Wanted: Medical Educators in Addiction Psychiatry.

Frances R.

Acad Psychiatry. 2018 Apr;42(2):273-276. doi: 10.1007/s40596-018-0888-4. Epub 2018 Feb 8. No abstract available.

PMID:
29423826
10.

Impact of circulating bacterial DNA in long-term glucose homeostasis in non-diabetic patients with HIV infection: cohort study.

Moreno-Pérez Ó, Giner L, Reus S, Boix V, Alfayate R, Frances R, Merino E, Pico A, Portilla J.

Eur J Clin Microbiol Infect Dis. 2018 Feb;37(2):313-318. doi: 10.1007/s10096-017-3134-1. Epub 2017 Dec 2.

PMID:
29197988
11.

Complete Genome Sequence of Porphyrobacter sp. Strain CACIAM 03H1, a Proteobacterium Obtained from a Nonaxenic Culture of Microcystis aeruginosa.

Castro WO, Lima ARJ, Moraes PHG, Siqueira AS, Aguiar DCF, Baraúna ARF, Martins LC, Fuzii HT, Couto DCC, Francês RSK, Silva de Lima CP, Vianez-Júnior JLSG, Nunes MRT, Dall'Agnol LT, Gonçalves EC.

Genome Announc. 2017 Oct 12;5(41). pii: e01069-17. doi: 10.1128/genomeA.01069-17.

12.

IL26 modulates cytokine response and anti-TNF consumption in Crohn's disease patients with bacterial DNA.

Piñero P, Juanola O, Gutiérrez A, Zapater P, Giménez P, Steinert A, Sempere L, González-Navajas JM, Niess JH, Francés R.

J Mol Med (Berl). 2017 Nov;95(11):1227-1236. doi: 10.1007/s00109-017-1585-6. Epub 2017 Sep 6.

PMID:
28879509
13.

Norfloxacin is more effective than Rifaximin in avoiding bacterial translocation in an animal model of cirrhosis.

Gómez-Hurtado I, Gimenez P, García I, Zapater P, Francés R, González-Navajas JM, Manichanh C, Ramos JM, Bellot P, Guarner F, Such J.

Liver Int. 2018 Feb;38(2):295-302. doi: 10.1111/liv.13551. Epub 2017 Sep 13.

PMID:
28834270
14.

Toll-like receptor polymorphisms compromise the inflammatory response against bacterial antigen translocation in cirrhosis.

Piñero P, Juanola O, Caparrós E, Zapater P, Giménez P, González-Navajas JM, Such J, Francés R.

Sci Rep. 2017 Apr 18;7:46425. doi: 10.1038/srep46425.

15.

The expression and activation of the AIM2 inflammasome correlates with inflammation and disease severity in patients with acute pancreatitis.

Algaba-Chueca F, de-Madaria E, Lozano-Ruiz B, Martínez-Cardona C, Quesada-Vázquez N, Bachiller V, Tarín F, Such J, Francés R, Zapater P, González-Navajas JM.

Pancreatology. 2017 May - Jun;17(3):364-371. doi: 10.1016/j.pan.2017.03.006. Epub 2017 Mar 18.

PMID:
28342645
16.

Lactulose reduces bacterial DNA translocation, which worsens neurocognitive shape in cirrhotic patients with minimal hepatic encephalopathy.

Moratalla A, Ampuero J, Bellot P, Gallego-Durán R, Zapater P, Roger M, Figueruela B, Martínez-Moreno B, González-Navajas JM, Such J, Romero-Gómez M, Francés R.

Liver Int. 2017 Feb;37(2):212-223. doi: 10.1111/liv.13200. Epub 2016 Jul 29.

PMID:
27388776
17.

Selective intestinal decontamination with norfloxacin enhances a regulatory T cell-mediated inflammatory control mechanism in cirrhosis.

Juanola O, Gómez-Hurtado I, Zapater P, Moratalla A, Caparrós E, Piñero P, González-Navajas JM, Giménez P, Such J, Francés R.

Liver Int. 2016 Dec;36(12):1811-1820. doi: 10.1111/liv.13172. Epub 2016 Jun 21.

PMID:
27214392
18.

Grade of soluble inflammatory response is mainly affected by circulating bacterial DNA concentrations in cirrhosis.

Caro E, Francés R, Zapater P, Pascual S, Bellot P, Such J.

Liver Int. 2016 Oct;36(10):1473-80. doi: 10.1111/liv.13118. Epub 2016 Apr 28.

PMID:
26991936
19.

Gut Bacterial DNA Translocation is an Independent Risk Factor of Flare at Short Term in Patients With Crohn's Disease.

Gutiérrez A, Zapater P, Juanola O, Sempere L, García M, Laveda R, Martínez A, Scharl M, González-Navajas JM, Such J, Wiest R, Rogler G, Francés R.

Am J Gastroenterol. 2016 Apr;111(4):529-40. doi: 10.1038/ajg.2016.8. Epub 2016 Feb 23.

20.

Microbiome and bacterial translocation in cirrhosis.

Gómez-Hurtado I, Such J, Francés R.

Gastroenterol Hepatol. 2016 Dec;39(10):687-696. doi: 10.1016/j.gastrohep.2015.10.013. Epub 2016 Jan 13. Review. English, Spanish.

PMID:
26775042
21.

Immunomodulating effects of antibiotics used in the prophylaxis of bacterial infections in advanced cirrhosis.

Zapater P, González-Navajas JM, Such J, Francés R.

World J Gastroenterol. 2015 Nov 7;21(41):11493-501. doi: 10.3748/wjg.v21.i41.11493. Review.

22.

Bifidobacterium pseudocatenulatum CECT7765 induces an M2 anti-inflammatory transition in macrophages from patients with cirrhosis.

Moratalla A, Caparrós E, Juanola O, Portune K, Puig-Kröger A, Estrada-Capetillo L, Bellot P, Gómez-Hurtado I, Piñero P, Zapater P, González-Navajas JM, Such J, Sanz Y, Francés R.

J Hepatol. 2016 Jan;64(1):135-45. doi: 10.1016/j.jhep.2015.08.020. Epub 2015 Aug 31.

PMID:
26334579
23.

Identification of Bacterial DNA in the Peripheral Blood of Patients With Active Psoriasis.

Ramírez-Boscá A, Navarro-López V, Martínez-Andrés A, Such J, Francés R, Horga de la Parte J, Asín-Llorca M.

JAMA Dermatol. 2015 Jun;151(6):670-1. doi: 10.1001/jamadermatol.2014.5585. No abstract available.

PMID:
25760018
24.

Bifidobacterium pseudocatenulatum CECT7765 promotes a TLR2-dependent anti-inflammatory response in intestinal lymphocytes from mice with cirrhosis.

Moratalla A, Gómez-Hurtado I, Moya-Pérez Á, Zapater P, Peiró G, González-Navajas JM, Gómez Del Pulgar EM, Such J, Sanz Y, Francés R.

Eur J Nutr. 2016 Feb;55(1):197-206. doi: 10.1007/s00394-015-0837-x. Epub 2015 Feb 6.

PMID:
25657013
25.

Anti-TNF-alpha loss of response is associated with a decreased percentage of FoxP3+ T cells and a variant NOD2 genotype in patients with Crohn's disease.

Juanola O, Moratalla A, Gutiérrez A, Sempere L, Zapater P, Giménez P, Almenta I, Peiró G, González-Navajas JM, Such JF, Francés R.

J Gastroenterol. 2015 Jul;50(7):758-68. doi: 10.1007/s00535-014-1020-5. Epub 2014 Dec 11.

PMID:
25500977
26.

Gut microbiota-related complications in cirrhosis.

Gómez-Hurtado I, Such J, Sanz Y, Francés R.

World J Gastroenterol. 2014 Nov 14;20(42):15624-31. doi: 10.3748/wjg.v20.i42.15624. Review.

27.

Dual-specificity phosphatase 6 regulates CD4+ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice.

Bertin S, Lozano-Ruiz B, Bachiller V, García-Martínez I, Herdman S, Zapater P, Francés R, Such J, Lee J, Raz E, González-Navajas JM.

Mucosal Immunol. 2015 May;8(3):505-15. doi: 10.1038/mi.2014.84. Epub 2014 Sep 17.

28.

Absent in melanoma 2 triggers a heightened inflammasome response in ascitic fluid macrophages of patients with cirrhosis.

Lozano-Ruiz B, Bachiller V, García-Martínez I, Zapater P, Gómez-Hurtado I, Moratalla A, Giménez P, Bellot P, Francés R, Such J, González-Navajas JM.

J Hepatol. 2015 Jan;62(1):64-71. doi: 10.1016/j.jhep.2014.08.027. Epub 2014 Aug 27.

PMID:
25173967
29.

Acute effects of dipyrone on renal function in patients with cirrhosis: a randomized controlled trial.

Zapater P, Llanos L, Barquero C, Bellot P, Pascual S, Carnicer F, Palazón JM, Gimenez P, Esteban A, Llorca L, Francés R, Horga JF, Such J.

Basic Clin Pharmacol Toxicol. 2015 Mar;116(3):257-63. doi: 10.1111/bcpt.12312. Epub 2014 Oct 8.

30.

Regulatory role of PI3K-protein kinase B on the release of interleukin-1β in peritoneal macrophages from the ascites of cirrhotic patients.

Tapia-Abellán A, Ruiz-Alcaraz AJ, Antón G, Miras-López M, Francés R, Such J, Martínez-Esparza M, García-Peñarrubia P.

Clin Exp Immunol. 2014 Dec;178(3):525-36. doi: 10.1111/cei.12428.

31.

Use of proton pump inhibitors decrease cellular oxidative burst in patients with decompensated cirrhosis.

Garcia-Martinez I, Francés R, Zapater P, Giménez P, Gómez-Hurtado I, Moratalla A, Lozano-Ruiz B, Bellot P, González-Navajas JM, Such J.

J Gastroenterol Hepatol. 2015 Jan;30(1):147-54. doi: 10.1111/jgh.12667.

PMID:
25039465
32.

Role of interleukin 10 in norfloxacin prevention of luminal free endotoxin translocation in mice with cirrhosis.

Gómez-Hurtado I, Moratalla A, Moya-Pérez Á, Peiró G, Zapater P, González-Navajas JM, Giménez P, Such J, Sanz Y, Francés R.

J Hepatol. 2014 Oct;61(4):799-808. doi: 10.1016/j.jhep.2014.05.031. Epub 2014 Jun 2.

PMID:
24882049
33.

Bacterial DNA translocation holds increased insulin resistance and systemic inflammatory levels in morbid obese patients.

Ortiz S, Zapater P, Estrada JL, Enriquez P, Rey M, Abad A, Such J, Lluis F, Francés R.

J Clin Endocrinol Metab. 2014 Jul;99(7):2575-83. doi: 10.1210/jc.2013-4483. Epub 2014 Apr 15.

PMID:
24735424
34.

Oral probiotic VSL#3 attenuates the circulatory disturbances of patients with cirrhosis and ascites.

Rincón D, Vaquero J, Hernando A, Galindo E, Ripoll C, Puerto M, Salcedo M, Francés R, Matilla A, Catalina MV, Clemente G, Such J, Bañares R.

Liver Int. 2014 Nov;34(10):1504-12. doi: 10.1111/liv.12539. Epub 2014 Apr 4.

PMID:
24661740
35.

Protective effect of Bifidobacterium pseudocatenulatum CECT7765 against induced bacterial antigen translocation in experimental cirrhosis.

Moratalla A, Gómez-Hurtado I, Santacruz A, Moya Á, Peiró G, Zapater P, González-Navajas JM, Giménez P, Such J, Sanz Y, Francés R.

Liver Int. 2014 Jul;34(6):850-8. doi: 10.1111/liv.12380. Epub 2013 Nov 24.

PMID:
24267920
36.

[Association between inflammatory markers and microbial translocation in patients with human immunodeficiency virus infection taking antiretroviral treatment].

Reus Bañuls S, Portilla Sogorb J, Sanchez-Paya J, Boix Martínez V, Giner Oncina L, Frances R, Such J, Merino Lucas E, Gimeno Gascón A.

Med Clin (Barc). 2014 Jan 21;142(2):47-52. doi: 10.1016/j.medcli.2013.05.044. Epub 2013 Oct 8. Spanish.

PMID:
24120098
37.

Modulation of inflammatory response in a cirrhotic rat model with induced bacterial peritonitis.

Sánchez E, Francés R, Soriano G, Mirelis B, Sancho FJ, González-Navajas JM, Muñoz C, Song XY, Pérez-Mateo M, Such J, Guarner C.

PLoS One. 2013;8(3):e59692. doi: 10.1371/journal.pone.0059692. Epub 2013 Mar 20.

38.

Genetic susceptibility to increased bacterial translocation influences the response to biological therapy in patients with Crohn's disease.

Gutiérrez A, Scharl M, Sempere L, Holler E, Zapater P, Almenta I, González-Navajas JM, Such J, Wiest R, Rogler G, Francés R.

Gut. 2014 Feb;63(2):272-80. doi: 10.1136/gutjnl-2012-303557. Epub 2013 Feb 1.

39.

Role of MAP kinases and PI3K-Akt on the cytokine inflammatory profile of peritoneal macrophages from the ascites of cirrhotic patients.

Tapia-Abellán A, Ruiz-Alcaraz AJ, Hernández-Caselles T, Such J, Francés R, García-Peñarrubia P, Martínez-Esparza M.

Liver Int. 2013 Apr;33(4):552-60. doi: 10.1111/liv.12072. Epub 2013 Jan 20.

PMID:
23331611
40.

Pathological bacterial translocation in cirrhosis: pathophysiology, diagnosis and clinical implications.

Bellot P, Francés R, Such J.

Liver Int. 2013 Jan;33(1):31-9. doi: 10.1111/liv.12021. Epub 2012 Nov 4. Review.

PMID:
23121656
41.

Low-level HIV viremia is associated with microbial translocation and inflammation.

Reus S, Portilla J, Sánchez-Payá J, Giner L, Francés R, Such J, Boix V, Merino E, Gimeno A.

J Acquir Immune Defic Syndr. 2013 Feb 1;62(2):129-34. doi: 10.1097/QAI.0b013e3182745ab0.

PMID:
23018379
42.

Beta-adrenergic receptor 1 selective antagonism inhibits norepinephrine-mediated TNF-alpha downregulation in experimental liver cirrhosis.

Zapater P, Gómez-Hurtado I, Peiró G, González-Navajas JM, García I, Giménez P, Moratalla A, Such J, Francés R.

PLoS One. 2012;7(8):e43371. doi: 10.1371/journal.pone.0043371. Epub 2012 Aug 20.

43.

The peritoneal macrophage inflammatory profile in cirrhosis depends on the alcoholic or hepatitis C viral etiology and is related to ERK phosphorylation.

Tapia-Abellán A, Martínez-Esparza M, Ruiz-Alcaraz AJ, Hernández-Caselles T, Martínez-Pascual C, Miras-López M, Such J, Francés R, García-Peñarrubia P.

BMC Immunol. 2012 Aug 6;13:42. doi: 10.1186/1471-2172-13-42.

44.

Interaction between intestinal dendritic cells and bacteria translocated from the gut in rats with cirrhosis.

Muñoz L, José Borrero M, Ubeda M, Lario M, Díaz D, Francés R, Monserrat J, Pastor O, Aguado-Fraile E, Such J, Alvarez-Mon M, Albillos A.

Hepatology. 2012 Nov;56(5):1861-9. doi: 10.1002/hep.25854. Epub 2012 Sep 17.

PMID:
22611024
45.

Commentary on 'A didactic note on alcoholism'.

Frances RJ.

J Nerv Ment Dis. 2012 Apr;200(4):288-9. doi: 10.1097/NMD.0b013e31824cb0dd. No abstract available.

PMID:
22456580
46.

Cardiac resynchronization therapy in patients with permanent atrial fibrillation. Is it mandatory to ablate the atrioventricular junction to obtain a good response?

Tolosana JM, Arnau AM, Madrid AH, Macias A, Lozano IF, Osca J, Quesada A, Toquero J, Francés RM, Bolao IG, Berruezo A, Sitges M, Alcalá MG, Brugada J, Mont L; SPARE II investigators (Spanish Atrial Resynchronization Study II).

Eur J Heart Fail. 2012 Jun;14(6):635-41. doi: 10.1093/eurjhf/hfs024. Epub 2012 Mar 6.

47.

Gut microbiota dysbiosis is associated with inflammation and bacterial translocation in mice with CCl4-induced fibrosis.

Gómez-Hurtado I, Santacruz A, Peiró G, Zapater P, Gutiérrez A, Pérez-Mateo M, Sanz Y, Francés R.

PLoS One. 2011;6(7):e23037. doi: 10.1371/journal.pone.0023037. Epub 2011 Jul 29.

48.

Antimicrobial peptide response to blood translocation of bacterial DNA in Crohn's disease is affected by NOD2/CARD15 genotype.

Gutiérrez A, Holler E, Zapater P, Sempere L, Jover R, Pérez-Mateo M, Schoelmerich J, Such J, Wiest R, Francés R.

Inflamm Bowel Dis. 2011 Aug;17(8):1641-50. doi: 10.1002/ibd.21537. Epub 2010 Nov 15.

PMID:
21744420
49.

Geriatric addictions.

Frances RJ.

Am J Geriatr Psychiatry. 2011 Aug;19(8):681-4. doi: 10.1097/JGP.0b013e31821fff89. No abstract available.

PMID:
21685782
50.

Interleukin-10-mediated heme oxygenase 1-induced underlying mechanism in inflammatory down-regulation by norfloxacin in cirrhosis.

Gómez-Hurtado I, Zapater P, Bellot P, Pascual S, Pérez-Mateo M, Such J, Francés R.

Hepatology. 2011 Mar;53(3):935-44. doi: 10.1002/hep.24102.

PMID:
21374664

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