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Items: 21


Acute Lymphoblastic Leukaemia Cells Impair Dendritic Cell and Macrophage Differentiation: Role of BMP4.

Valencia J, M Fernández-Sevilla L, Fraile-Ramos A, Sacedón R, Jiménez E, Vicente A, Varas A.

Cells. 2019 Jul 14;8(7). pii: E722. doi: 10.3390/cells8070722.


Protein Kinase C δ Regulates the Depletion of Actin at the Immunological Synapse Required for Polarized Exosome Secretion by T Cells.

Herranz G, Aguilera P, Dávila S, Sánchez A, Stancu B, Gómez J, Fernández-Moreno D, de Martín R, Quintanilla M, Fernández T, Rodríguez-Silvestre P, Márquez-Expósito L, Bello-Gamboa A, Fraile-Ramos A, Calvo V, Izquierdo M.

Front Immunol. 2019 Apr 26;10:851. doi: 10.3389/fimmu.2019.00851. eCollection 2019.


Tracking Endocytosis and Intracellular Trafficking of Epitope-tagged Syntaxin 3 by Antibody Feeding in Live, Polarized MDCK Cells.

Giovannone AJ, Reales E, Bhattaram P, Fraile-Ramos A, Weimbs T.

Bio Protoc. 2018 Feb 5;8(3). pii: e2453. doi: 10.21769/BioProtoc.2453.


Monoubiquitination of syntaxin 3 leads to retrieval from the basolateral plasma membrane and facilitates cargo recruitment to exosomes.

Giovannone AJ, Reales E, Bhattaram P, Fraile-Ramos A, Weimbs T.

Mol Biol Cell. 2017 Oct 15;28(21):2843-2853. doi: 10.1091/mbc.E17-07-0461. Epub 2017 Aug 16.


Human cytomegalovirus encoded chemokine receptor US28 activates the HIF-1α/PKM2 axis in glioblastoma cells.

de Wit RH, Mujić-Delić A, van Senten JR, Fraile-Ramos A, Siderius M, Smit MJ.

Oncotarget. 2016 Oct 18;7(42):67966-67985. doi: 10.18632/oncotarget.11817.


Role of Proteolipid Protein in HSV-1 Entry in Oligodendrocytic Cells.

Bello-Morales R, Crespillo AJ, Praena B, Tabarés E, Revilla Y, García E, Fraile-Ramos A, Baron W, Krummenacher C, López-Guerrero JA.

PLoS One. 2016 Jan 25;11(1):e0147885. doi: 10.1371/journal.pone.0147885. eCollection 2016.


Role of the small GTPase Rab27a during herpes simplex virus infection of oligodendrocytic cells.

Bello-Morales R, Crespillo AJ, Fraile-Ramos A, Tabarés E, Alcina A, López-Guerrero JA.

BMC Microbiol. 2012 Nov 19;12:265. doi: 10.1186/1471-2180-12-265.


A role for the SNARE protein syntaxin 3 in human cytomegalovirus morphogenesis.

Cepeda V, Fraile-Ramos A.

Cell Microbiol. 2011 Jun;13(6):846-58. doi: 10.1111/j.1462-5822.2011.01583.x. Epub 2011 Mar 4.


Diacylglycerol kinase α regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes.

Alonso R, Mazzeo C, Rodriguez MC, Marsh M, Fraile-Ramos A, Calvo V, Avila-Flores A, Merida I, Izquierdo M.

Cell Death Differ. 2011 Jul;18(7):1161-73. doi: 10.1038/cdd.2010.184. Epub 2011 Jan 21.


Rab27a is required for human cytomegalovirus assembly.

Fraile-Ramos A, Cepeda V, Elstak E, van der Sluijs P.

PLoS One. 2010 Dec 8;5(12):e15318. doi: 10.1371/journal.pone.0015318.


The cytomegalovirus-encoded chemokine receptor US28 promotes intestinal neoplasia in transgenic mice.

Bongers G, Maussang D, Muniz LR, Noriega VM, Fraile-Ramos A, Barker N, Marchesi F, Thirunarayanan N, Vischer HF, Qin L, Mayer L, Harpaz N, Leurs R, Furtado GC, Clevers H, Tortorella D, Smit MJ, Lira SA.

J Clin Invest. 2010 Nov;120(11):3969-78. doi: 10.1172/JCI42563. Epub 2010 Oct 11.


HCMV-encoded chemokine receptor US28 mediates proliferative signaling through the IL-6-STAT3 axis.

Slinger E, Maussang D, Schreiber A, Siderius M, Rahbar A, Fraile-Ramos A, Lira SA, Söderberg-Nauclér C, Smit MJ.

Sci Signal. 2010 Aug 3;3(133):ra58. doi: 10.1126/scisignal.2001180.


Human cytomegalovirus final envelopment on membranes containing both trans-Golgi network and endosomal markers.

Cepeda V, Esteban M, Fraile-Ramos A.

Cell Microbiol. 2010 Mar;12(3):386-404. doi: 10.1111/j.1462-5822.2009.01405.x. Epub 2009 Nov 2.


Membrane remodelling during vaccinia virus morphogenesis.

Chichón FJ, Rodríguez MJ, Risco C, Fraile-Ramos A, Fernández JJ, Esteban M, Carrascosa JL.

Biol Cell. 2009 Jul;101(7):401-14. doi: 10.1042/BC20080176.


The ESCRT machinery is not required for human cytomegalovirus envelopment.

Fraile-Ramos A, Pelchen-Matthews A, Risco C, Rejas MT, Emery VC, Hassan-Walker AF, Esteban M, Marsh M.

Cell Microbiol. 2007 Dec;9(12):2955-67. Epub 2007 Aug 29.


Novel replication complex architecture in rubella replicon-transfected cells.

Fontana J, Tzeng WP, Calderita G, Fraile-Ramos A, Frey TK, Risco C.

Cell Microbiol. 2007 Apr;9(4):875-90. Epub 2006 Nov 3.


NK1 receptor fused to beta-arrestin displays a single-component, high-affinity molecular phenotype.

Martini L, Hastrup H, Holst B, Fraile-Ramos A, Marsh M, Schwartz TW.

Mol Pharmacol. 2002 Jul;62(1):30-7.


Localization of HCMV UL33 and US27 in endocytic compartments and viral membranes.

Fraile-Ramos A, Pelchen-Matthews A, Kledal TN, Browne H, Schwartz TW, Marsh M.

Traffic. 2002 Mar;3(3):218-32.


The human cytomegalovirus US28 protein is located in endocytic vesicles and undergoes constitutive endocytosis and recycling.

Fraile-Ramos A, Kledal TN, Pelchen-Matthews A, Bowers K, Schwartz TW, Marsh M.

Mol Biol Cell. 2001 Jun;12(6):1737-49.


Chemokine receptor trafficking and viral replication.

Pelchen-Matthews A, Signoret N, Klasse PJ, Fraile-Ramos A, Marsh M.

Immunol Rev. 1999 Apr;168:33-49. Review.


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