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Items: 38

1.

Assessing the modulation of cutaneous sensory fiber excitability using a fast perception threshold tracking technique.

Nielson Hoberg T, Frahm S, Hennings K, Arendt-Nielsen L, Dahl Mørch C.

Muscle Nerve. 2019 May 20. doi: 10.1002/mus.26520. [Epub ahead of print]

PMID:
31107560
2.

A novel cell-free method to culture Schistosoma mansoni from cercariae to juvenile worm stages for in vitro drug testing.

Frahm S, Anisuzzaman A, Prodjinotho UF, Vejzagić N, Verschoor A, Prazeres da Costa C.

PLoS Negl Trop Dis. 2019 Jan 28;13(1):e0006590. doi: 10.1371/journal.pntd.0006590. eCollection 2019 Jan.

3.

Increased Cholinergic Response in α-Synuclein Transgenic Mice (h-α-synL62).

König M, Berlin B, Schwab K, Frahm S, Theuring F, Wischik CM, Harrington CR, Riedel G, Klein J.

ACS Chem Neurosci. 2019 Apr 17;10(4):1915-1922. doi: 10.1021/acschemneuro.8b00274. Epub 2018 Sep 28.

PMID:
30253092
4.

A Protein Aggregation Inhibitor, Leuco-Methylthioninium Bis(Hydromethanesulfonate), Decreases α-Synuclein Inclusions in a Transgenic Mouse Model of Synucleinopathy.

Schwab K, Frahm S, Horsley D, Rickard JE, Melis V, Goatman EA, Magbagbeolu M, Douglas M, Leith MG, Baddeley TC, Storey JMD, Riedel G, Wischik CM, Harrington CR, Theuring F.

Front Mol Neurosci. 2018 Jan 10;10:447. doi: 10.3389/fnmol.2017.00447. eCollection 2017.

5.

Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease.

Frahm S, Melis V, Horsley D, Rickard JE, Riedel G, Fadda P, Scherma M, Harrington CR, Wischik CM, Theuring F, Schwab K.

Behav Brain Res. 2018 Feb 26;339:153-168. doi: 10.1016/j.bbr.2017.11.025. Epub 2017 Nov 24.

6.

An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence.

Frahm S, Antolin-Fontes B, Görlich A, Zander JF, Ahnert-Hilger G, Ibañez-Tallon I.

Elife. 2015 Dec 1;4:e11396. doi: 10.7554/eLife.11396.

7.

Suppression of Peripheral Pain by Blockade of Voltage-Gated Calcium 2.2 Channels in Nociceptors Induces RANKL and Impairs Recovery From Inflammatory Arthritis in a Mouse Model.

Baddack U, Frahm S, Antolin-Fontes B, Grobe J, Lipp M, Müller G, Ibañez-Tallon I.

Arthritis Rheumatol. 2015 Jun;67(6):1657-67. doi: 10.1002/art.39094.

8.

De novo insertions and deletions of predominantly paternal origin are associated with autism spectrum disorder.

Dong S, Walker MF, Carriero NJ, DiCola M, Willsey AJ, Ye AY, Waqar Z, Gonzalez LE, Overton JD, Frahm S, Keaney JF 3rd, Teran NA, Dea J, Mandell JD, Hus Bal V, Sullivan CA, DiLullo NM, Khalil RO, Gockley J, Yuksel Z, Sertel SM, Ercan-Sencicek AG, Gupta AR, Mane SM, Sheldon M, Brooks AI, Roeder K, Devlin B, State MW, Wei L, Sanders SJ.

Cell Rep. 2014 Oct 9;9(1):16-23. doi: 10.1016/j.celrep.2014.08.068. Epub 2014 Oct 2.

9.

Habenular expression of rare missense variants of the β4 nicotinic receptor subunit alters nicotine consumption.

Slimak MA, Ables JL, Frahm S, Antolin-Fontes B, Santos-Torres J, Moretti M, Gotti C, Ibañez-Tallon I.

Front Hum Neurosci. 2014 Jan 27;8:12. doi: 10.3389/fnhum.2014.00012. eCollection 2014.

10.

Reexposure to nicotine during withdrawal increases the pacemaking activity of cholinergic habenular neurons.

Görlich A, Antolin-Fontes B, Ables JL, Frahm S, Slimak MA, Dougherty JD, Ibañez-Tallon I.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):17077-82. doi: 10.1073/pnas.1313103110. Epub 2013 Sep 30.

11.

Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism.

Sanders SJ, Ercan-Sencicek AG, Hus V, Luo R, Murtha MT, Moreno-De-Luca D, Chu SH, Moreau MP, Gupta AR, Thomson SA, Mason CE, Bilguvar K, Celestino-Soper PB, Choi M, Crawford EL, Davis L, Wright NR, Dhodapkar RM, DiCola M, DiLullo NM, Fernandez TV, Fielding-Singh V, Fishman DO, Frahm S, Garagaloyan R, Goh GS, Kammela S, Klei L, Lowe JK, Lund SC, McGrew AD, Meyer KA, Moffat WJ, Murdoch JD, O'Roak BJ, Ober GT, Pottenger RS, Raubeson MJ, Song Y, Wang Q, Yaspan BL, Yu TW, Yurkiewicz IR, Beaudet AL, Cantor RM, Curland M, Grice DE, Günel M, Lifton RP, Mane SM, Martin DM, Shaw CA, Sheldon M, Tischfield JA, Walsh CA, Morrow EM, Ledbetter DH, Fombonne E, Lord C, Martin CL, Brooks AI, Sutcliffe JS, Cook EH Jr, Geschwind D, Roeder K, Devlin B, State MW.

Neuron. 2011 Jun 9;70(5):863-85. doi: 10.1016/j.neuron.2011.05.002.

12.

Aversion to nicotine is regulated by the balanced activity of β4 and α5 nicotinic receptor subunits in the medial habenula.

Frahm S, Slimak MA, Ferrarese L, Santos-Torres J, Antolin-Fontes B, Auer S, Filkin S, Pons S, Fontaine JF, Tsetlin V, Maskos U, Ibañez-Tallon I.

Neuron. 2011 May 12;70(3):522-35. doi: 10.1016/j.neuron.2011.04.013.

13.

The molecular and cellular identity of peripheral osmoreceptors.

Lechner SG, Markworth S, Poole K, Smith ES, Lapatsina L, Frahm S, May M, Pischke S, Suzuki M, Ibañez-Tallon I, Luft FC, Jordan J, Lewin GR.

Neuron. 2011 Jan 27;69(2):332-44. doi: 10.1016/j.neuron.2010.12.028.

14.

An in vivo tethered toxin approach for the cell-autonomous inactivation of voltage-gated sodium channel currents in nociceptors.

Stürzebecher AS, Hu J, Smith ES, Frahm S, Santos-Torres J, Kampfrath B, Auer S, Lewin GR, Ibañez-Tallon I.

J Physiol. 2010 May 15;588(Pt 10):1695-707. doi: 10.1113/jphysiol.2010.187112. Epub 2010 Mar 22.

15.

Silencing neurotransmission with membrane-tethered toxins.

Auer S, Stürzebecher AS, Jüttner R, Santos-Torres J, Hanack C, Frahm S, Liehl B, Ibañez-Tallon I.

Nat Methods. 2010 Mar;7(3):229-36. doi: 10.1038/nmeth.1425. Epub 2010 Feb 7.

PMID:
20139968
16.

Ras signaling influences permissiveness of malignant peripheral nerve sheath tumor cells to oncolytic herpes.

Farassati F, Pan W, Yamoutpour F, Henke S, Piedra M, Frahm S, Al-Tawil S, Mangrum WI, Parada LF, Rabkin SD, Martuza RL, Kurtz A.

Am J Pathol. 2008 Dec;173(6):1861-72. doi: 10.2353/ajpath.2008.080376. Epub 2008 Nov 6.

17.

Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues.

Miller SJ, Rangwala F, Williams J, Ackerman P, Kong S, Jegga AG, Kaiser S, Aronow BJ, Frahm S, Kluwe L, Mautner V, Upadhyaya M, Muir D, Wallace M, Hagen J, Quelle DE, Watson MA, Perry A, Gutmann DH, Ratner N.

Cancer Res. 2006 Mar 1;66(5):2584-91.

18.

[Follicular papules and plaques with effluvium].

Hummel S, Frahm SO, Hartschuh W.

J Dtsch Dermatol Ges. 2004 Nov;2(11):953-5. German. No abstract available.

PMID:
16281615
19.

Signal therapy of NF1-deficient tumor xenograft in mice by the anti-PAK1 drug FK228.

Hirokawa Y, Nakajima H, Hanemann CO, Kurtz A, Frahm S, Mautner V, Maruta H.

Cancer Biol Ther. 2005 Apr;4(4):379-81. Epub 2005 Apr 4.

PMID:
15846074
20.

Differential modulation of malignant peripheral nerve sheath tumor growth by omega-3 and omega-6 fatty acids.

Mashour GA, Drissel SN, Frahm S, Farassati F, Martuza RL, Mautner VF, Kindler-Röhrborn A, Kurtz A.

Oncogene. 2005 Mar 31;24(14):2367-74.

PMID:
15735744
21.

Minichromosome maintenance protein (MCM6) in low-grade chondrosarcoma: distinction from enchondroma and identification of progressive tumors.

Helfenstein A, Frahm SO, Krams M, Drescher W, Parwaresch R, Hassenpflug J.

Am J Clin Pathol. 2004 Dec;122(6):912-8.

PMID:
15539383
22.

Subclassification of nerve sheath tumors by gene expression profiling.

Holtkamp N, Reuss DE, Atallah I, Kuban RJ, Hartmann C, Mautner VF, Frahm S, Friedrich RE, Algermissen B, Pham VA, Prietz S, Rosenbaum T, Estevez-Schwarz L, von Deimling A.

Brain Pathol. 2004 Jul;14(3):258-64.

PMID:
15446580
23.

Genetic and phenotypic characterization of tumor cells derived from malignant peripheral nerve sheath tumors of neurofibromatosis type 1 patients.

Frahm S, Mautner VF, Brems H, Legius E, Debiec-Rychter M, Friedrich RE, Knöfel WT, Peiper M, Kluwe L.

Neurobiol Dis. 2004 Jun;16(1):85-91.

PMID:
15207265
24.

Sulindac derivatives inhibit cell growth and induce apoptosis in primary cells from malignant peripheral nerve sheath tumors of NF1-patients.

Frahm S, Kurtz A, Kluwe L, Farassati F, Friedrich RE, Mautner VF.

Cancer Cell Int. 2004 May 17;4(1):4.

25.

Elevated risk for MPNST in NF1 microdeletion patients.

De Raedt T, Brems H, Wolkenstein P, Vidaud D, Pilotti S, Perrone F, Mautner V, Frahm S, Sciot R, Legius E.

Am J Hum Genet. 2003 May;72(5):1288-92. Epub 2003 Mar 26.

26.

High proliferative activity may predict early metastasis of thin melanomas.

Frahm SO, Schubert C, Parwaresch R, Rudolph P.

Hum Pathol. 2001 Dec;32(12):1376-81.

PMID:
11774172
27.

Ki-Mcm6, a new monoclonal antibody specific to Mcm6: comparison of the distribution profile of Mcm6 and the Ki-67 antigen.

Heidebrecht HJ, Buck F, Endl E, Kruse ML, Adam-Klages S, Andersen K, Frahm SO, Schulte C, Wacker HH, Parwaresch R.

Lab Invest. 2001 Aug;81(8):1163-5. No abstract available.

PMID:
11502867
28.

High telomerase activity is associated with cell cycle deregulation and rapid progression in endometrioid adenocarcinoma of the uterus.

Bonatz G, Frahm SO, Klapper W, Helfenstein A, Heidorn K, Jonat W, Krupp G, Parwaresch R, Rudolph P.

Hum Pathol. 2001 Jun;32(6):605-14.

PMID:
11431715
29.

Proliferation marker Ki-S11--a prognostic indicator for squamous cell carcinoma of the hypopharynx.

Kuropkat C, Rudolph P, Frahm SO, Parwaresch R, Werner JA.

Virchows Arch. 1999 Dec;435(6):590-5.

PMID:
10628801
30.

Prognostic significance of Ki-67 and topoisomerase IIalpha expression in infiltrating ductal carcinoma of the breast. A multivariate analysis of 863 cases.

Rudolph P, MacGrogan G, Bonichon F, Frahm SO, de Mascarel I, Trojani M, Durand M, Avril A, Coindre JM, Parwaresch R.

Breast Cancer Res Treat. 1999 May;55(1):61-71.

PMID:
10472780
31.

[Pigmented tumor of the mouth mucosa. Amalgam tattooing].

Paulsen F, Frahm SO, Rudert H.

HNO. 1999 May;47(5):510-1. German. No abstract available.

PMID:
10412663
32.

Cell lineage specificity in G-CSF receptor gene methylation.

Felgner J, Heidorn K, Körbächer D, Frahm SO, Parwaresch R.

Leukemia. 1999 Apr;13(4):530-4.

PMID:
10214858
33.

Immunoenzymatic detection of the new proliferation associated protein p100 by means of a cellular ELISA: specific detection of cells in cell cycle phases S, G2 and M.

Frahm SO, Rudolph P, Dworeck C, Zott B, Heidebrecht H, Steinmann J, Neppert J, Parwaresch R.

J Immunol Methods. 1999 Mar 4;223(2):147-53.

PMID:
10089093
34.

[Intact pregnancy with concomitant hydatidiform mole of a coexisting placenta].

Bonatz G, Weisner D, Frahm SO, Lütgkes J, Jonat W.

Z Geburtshilfe Neonatol. 1998 Sep;202(5):212-3. German.

PMID:
9857448
35.

Telomere shortening in uterine leiomyomas.

Bonatz G, Frahm SO, Andreas S, Heidorn K, Jonat W, Parwaresch R.

Am J Obstet Gynecol. 1998 Sep;179(3 Pt 1):591-6.

PMID:
9757957
36.

Improved ELISA proliferation assay (EPA) for the detection of in vitro cell proliferation by a new Ki-67-antigen directed monoclonal antibody (Ki-S3).

Frahm SO, Zott B, Dworeck C, Steinmann J, Neppert J, Parwaresch R.

J Immunol Methods. 1998 Feb 1;211(1-2):43-50.

PMID:
9617830
37.

Sinus-lining cells of the lymph nodes recognized as a dendritic cell type by the new monoclonal antibody Ki-M9.

Wacker HH, Frahm SO, Heidebrecht HJ, Parwaresch R.

Am J Pathol. 1997 Aug;151(2):423-34.

38.

Rural perinatal center. Development of a rural level II perinatal center.

Enberg RN, Cox RH, Frahm SM.

J Kans Med Soc. 1977 May;78(5):235-8, 253. No abstract available.

PMID:
858959

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