Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 201

1.

Epigenetic dysregulation of TET2 in human glioblastoma.

García MG, Carella A, Urdinguio RG, Bayón GF, Lopez V, Tejedor JR, Sierra MI, García-Toraño E, Santamarina P, Perez RF, Mangas C, Astudillo A, Corte-Torres MD, Sáenz-de-Santa-María I, Chiara MD, Fernández AF, Fraga MF.

Oncotarget. 2018 May 25;9(40):25922-25934. doi: 10.18632/oncotarget.25406. eCollection 2018 May 25.

2.

Loss of 5hmC identifies a new type of aberrant DNA hypermethylation in glioma.

Fernandez AF, Bayón GF, Sierra MI, Urdinguio RG, Toraño EG, García M, Carella A, Lopez V, Santamarina P, Pérez RF, Belmonte T, Ramon Tejedor J, Cobo I, Menendez P, Mangas C, Ferrero C, Rodrigo L, Astudillo A, Ortea I, Cueto Díaz S, Rodríguez-Gonzalez P, Ignacio García Alonso J, Mollejo M, Meléndez B, Dominguez G, Bonilla F, Fraga MF.

Hum Mol Genet. 2018 Jun 5. doi: 10.1093/hmg/ddy214. [Epub ahead of print]

PMID:
29878202
3.

Commentary on: From Bedside to Bench: The Effect of Muscular Denervation on Fat Grafting to the Breast by Comparing Take Rate, Quality, and Longevity.

Condé-Green A, Fraga MF.

Aesthet Surg J. 2018 Jun 2. doi: 10.1093/asj/sjy118. [Epub ahead of print] No abstract available.

PMID:
29868782
4.

Epigenome-wide analysis reveals specific DNA hypermethylation of T cells during human hematopoietic differentiation.

Tejedor JR, Bueno C, Cobo I, Bayón GF, Prieto C, Mangas C, Pérez RF, Santamarina P, Urdinguio RG, Menéndez P, Fraga MF, Fernández AF.

Epigenomics. 2018 Jul;10(7):903-923. doi: 10.2217/epi-2017-0163. Epub 2018 Apr 5.

PMID:
29620943
5.

Vectra 3D Imaging for Quantitative Volumetric Analysis of the Upper Limb: A Feasibility Study for Tracking Outcomes of Lymphedema Treatment.

Batista BN, Baiocchi JMT, Fraga MFP, Sampaio MMC, Barros ACD.

Plast Reconstr Surg. 2018 Apr;141(4):616e-617e. doi: 10.1097/PRS.0000000000004223. No abstract available.

PMID:
29595746
6.

Distinct chromatin signatures of DNA hypomethylation in aging and cancer.

Pérez RF, Tejedor JR, Bayón GF, Fernández AF, Fraga MF.

Aging Cell. 2018 Jun;17(3):e12744. doi: 10.1111/acel.12744. Epub 2018 Mar 5.

7.

DNA methylation reprogramming of human cancer cells by expression of a plant 5-methylcytosine DNA glycosylase.

Morales-Ruiz T, García-Ortiz MV, Devesa-Guerra I, Raya-Ruiz L, Tejedor JR, Bayón GF, Sierra MI, Fraga MF, Ariza RR, Roldán-Arjona T.

Epigenetics. 2018;13(1):95-107. doi: 10.1080/15592294.2017.1414128. Epub 2018 Feb 7.

PMID:
29235922
8.

Altered intragenic DNA methylation of HOOK2 gene in adipose tissue from individuals with obesity and type 2 diabetes.

Rodríguez-Rodero S, Menéndez-Torre E, Fernández-Bayón G, Morales-Sánchez P, Sanz L, Turienzo E, González JJ, Martinez-Faedo C, Suarez-Gutiérrez L, Ares J, Díaz-Naya L, Martin-Nieto A, Fernández-Morera JL, Fraga MF, Delgado-Álvarez E.

PLoS One. 2017 Dec 11;12(12):e0189153. doi: 10.1371/journal.pone.0189153. eCollection 2017.

9.

Quantification of Global DNA Methylation Levels by Mass Spectrometry.

Fernandez AF, Valledor L, Vallejo F, Cañal MJ, Fraga MF.

Methods Mol Biol. 2018;1708:49-58. doi: 10.1007/978-1-4939-7481-8_3.

PMID:
29224138
10.

SDHC Promoter Methylation, a Novel Pathogenic Mechanism in Parasympathetic Paragangliomas.

Bernardo-Castiñeira C, Valdés N, Sierra MI, Sáenz-de-Santa-María I, Bayón GF, Perez RF, Fernández AF, Fraga MF, Astudillo A, Menéndez R, Fernández B, Del Olmo M, Suarez C, Chiara MD.

J Clin Endocrinol Metab. 2018 Jan 1;103(1):295-305. doi: 10.1210/jc.2017-01702.

PMID:
29126304
11.

DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes.

Sierra MI, Rubio L, Bayón GF, Cobo I, Menendez P, Morales P, Mangas C, Urdinguio RG, Lopez V, Valdes A, Vales G, Marcos R, Torrecillas R, Fernández AF, Fraga MF.

Nanotoxicology. 2017 Sep;11(7):857-870. doi: 10.1080/17435390.2017.1371350. Epub 2017 Sep 13.

PMID:
28901819
12.

Generation and characterization of a human iPSC cell line expressing inducible Cas9 in the "safe harbor" AAVS1 locus.

Castaño J, Bueno C, Jiménez-Delgado S, Roca-Ho H, Fraga MF, Fernandez AF, Nakanishi M, Torres-Ruiz R, Rodríguez-Perales S, Menéndez P.

Stem Cell Res. 2017 May;21:137-140. doi: 10.1016/j.scr.2017.04.011. Epub 2017 Apr 22.

13.

Interindividual epigenetic variability: Sound or noise?

Tejedor JR, Fraga MF.

Bioessays. 2017 Jul;39(7). doi: 10.1002/bies.201700055. Epub 2017 Jun 7. Review.

PMID:
28590035
14.

The role of 5-hydroxymethylcytosine in development, aging and age-related diseases.

López V, Fernández AF, Fraga MF.

Ageing Res Rev. 2017 Aug;37:28-38. doi: 10.1016/j.arr.2017.05.002. Epub 2017 May 10. Review.

PMID:
28499883
15.

Differential analysis of genome-wide methylation and gene expression in mesenchymal stem cells of patients with fractures and osteoarthritis.

Del Real A, Pérez-Campo FM, Fernández AF, Sañudo C, Ibarbia CG, Pérez-Núñez MI, Criekinge WV, Braspenning M, Alonso MA, Fraga MF, Riancho JA.

Epigenetics. 2017 Feb;12(2):113-122. doi: 10.1080/15592294.2016.1271854. Epub 2016 Dec 16.

16.

The effect of exposure to nanoparticles and nanomaterials on the mammalian epigenome.

Sierra MI, Valdés A, Fernández AF, Torrecillas R, Fraga MF.

Int J Nanomedicine. 2016 Nov 25;11:6297-6306. eCollection 2016. Review.

17.

Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency.

Muñoz-López A, Romero-Moya D, Prieto C, Ramos-Mejía V, Agraz-Doblas A, Varela I, Buschbeck M, Palau A, Carvajal-Vergara X, Giorgetti A, Ford A, Lako M, Granada I, Ruiz-Xivillé N, Rodríguez-Perales S, Torres-Ruíz R, Stam RW, Fuster JL, Fraga MF, Nakanishi M, Cazzaniga G, Bardini M, Cobo I, Bayon GF, Fernandez AF, Bueno C, Menendez P.

Stem Cell Reports. 2016 Oct 11;7(4):602-618. doi: 10.1016/j.stemcr.2016.08.013. Epub 2016 Sep 22.

18.

Lipofilling of the Breast Does Not Increase the Risk of Recurrence of Breast Cancer: A Matched Controlled Study.

Batista BN, Fraga MF, Sampaio MM, Barros AC.

Plast Reconstr Surg. 2016 Dec;138(6):1068e-1069e. No abstract available.

PMID:
27537233
19.

Age-associated hydroxymethylation in human bone-marrow mesenchymal stem cells.

Toraño EG, Bayón GF, Del Real Á, Sierra MI, García MG, Carella A, Belmonte T, Urdinguio RG, Cubillo I, García-Castro J, Delgado-Calle J, Pérez-Campo FM, Riancho JA, Fraga MF, Fernández AF.

J Transl Med. 2016 Jul 8;14(1):207. doi: 10.1186/s12967-016-0966-x.

20.

Generation of a human iPSC line from a patient with Leigh syndrome caused by a mutation in the MT-ATP6 gene.

Galera-Monge T, Zurita-Díaz F, González-Páramos C, Moreno-Izquierdo A, Fraga MF, Fernández AF, Garesse R, Gallardo ME.

Stem Cell Res. 2016 May;16(3):766-9. doi: 10.1016/j.scr.2016.04.012. Epub 2016 Apr 18. No abstract available.

21.

Generation of a human iPSC line from a patient with an optic atrophy 'plus' phenotype due to a mutation in the OPA1 gene.

Galera-Monge T, Zurita-Díaz F, Moreno-Izquierdo A, Fraga MF, Fernández AF, Ayuso C, Garesse R, Gallardo ME.

Stem Cell Res. 2016 May;16(3):673-6. doi: 10.1016/j.scr.2016.03.011. Epub 2016 Apr 13.

22.

Generation of a human iPSC line from a patient with a mitochondrial encephalopathy due to mutations in the GFM1 gene.

Zurita-Díaz F, Galera-Monge T, Moreno-Izquierdo A, Fraga MF, Ayuso C, Fernández AF, Garesse R, Gallardo ME.

Stem Cell Res. 2016 Jan;16(1):124-7. doi: 10.1016/j.scr.2015.12.019. Epub 2015 Dec 29.

23.

Generation of a human iPSC line from a patient with a defect of intergenomic communication.

Zurita F, Galera T, González-Páramos C, Moreno-Izquierdo A, Schneiderat P, Fraga MF, Fernández AF, Garesse R, Gallardo ME.

Stem Cell Res. 2016 Jan;16(1):120-3. doi: 10.1016/j.scr.2015.12.016. Epub 2015 Dec 28.

24.

Generation of a human control iPSC line with a European mitochondrial haplogroup U background.

Galera T, Zurita F, González-Páramos C, Moreno-Izquierdo A, Fraga MF, Fernández AF, Garesse R, Gallardo ME.

Stem Cell Res. 2016 Jan;16(1):88-91. doi: 10.1016/j.scr.2015.12.010. Epub 2015 Dec 15.

25.

Generation of a human iPSC line from a patient with Leigh syndrome.

Galera T, Zurita F, González-Páramos C, Moreno-Izquierdo A, Fraga MF, Fernández AF, Garesse R, Gallardo ME.

Stem Cell Res. 2016 Jan;16(1):63-6. doi: 10.1016/j.scr.2015.12.005. Epub 2015 Dec 12.

26.

Longitudinal study of DNA methylation during the first 5 years of life.

Urdinguio RG, Torró MI, Bayón GF, Álvarez-Pitti J, Fernández AF, Redon P, Fraga MF, Lurbe E.

J Transl Med. 2016 Jun 3;14(1):160. doi: 10.1186/s12967-016-0913-x.

27.

Epigenetics of Aging.

Sierra MI, Fernández AF, Fraga MF.

Curr Genomics. 2015 Dec;16(6):435-40. doi: 10.2174/1389202916666150817203459.

28.

Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2.

Redis RS, Vela LE, Lu W, Ferreira de Oliveira J, Ivan C, Rodriguez-Aguayo C, Adamoski D, Pasculli B, Taguchi A, Chen Y, Fernandez AF, Valledor L, Van Roosbroeck K, Chang S, Shah M, Kinnebrew G, Han L, Atlasi Y, Cheung LH, Huang GY, Monroig P, Ramirez MS, Catela Ivkovic T, Van L, Ling H, Gafà R, Kapitanovic S, Lanza G, Bankson JA, Huang P, Lai SY, Bast RC, Rosenblum MG, Radovich M, Ivan M, Bartholomeusz G, Liang H, Fraga MF, Widger WR, Hanash S, Berindan-Neagoe I, Lopez-Berestein G, Ambrosio ALB, Gomes Dias SM, Calin GA.

Mol Cell. 2016 Feb 18;61(4):640. doi: 10.1016/j.molcel.2016.02.006. Epub 2016 Feb 18. No abstract available.

29.

Oncometabolic Nuclear Reprogramming of Cancer Stemness.

Menendez JA, Corominas-Faja B, Cuyàs E, García MG, Fernández-Arroyo S, Fernández AF, Joven J, Fraga MF, Alarcón T.

Stem Cell Reports. 2016 Mar 8;6(3):273-83. doi: 10.1016/j.stemcr.2015.12.012. Epub 2016 Feb 11.

30.

Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2.

Redis RS, Vela LE, Lu W, Ferreira de Oliveira J, Ivan C, Rodriguez-Aguayo C, Adamoski D, Pasculli B, Taguchi A, Chen Y, Fernandez AF, Valledor L, Van Roosbroeck K, Chang S, Shah M, Kinnebrew G, Han L, Atlasi Y, Cheung LH, Huang GY, Monroig P, Ramirez MS, Catela Ivkovic T, Van L, Ling H, Gafà R, Kapitanovic S, Lanza G, Bankson JA, Huang P, Lai SY, Bast RC, Rosenblum MG, Radovich M, Ivan M, Bartholomeusz G, Liang H, Fraga MF, Widger WR, Hanash S, Berindan-Neagoe I, Lopez-Berestein G, Ambrosio ALB, Gomes Dias SM, Calin GA.

Mol Cell. 2016 Feb 18;61(4):520-534. doi: 10.1016/j.molcel.2016.01.015. Epub 2016 Feb 4. Erratum in: Mol Cell. 2016 Feb 18;61(4):640.

31.

HERG1A potassium channel is the predominant isoform in head and neck squamous cell carcinomas: evidence for regulation by epigenetic mechanisms.

Menéndez ST, Villaronga MÁ, Rodrigo JP, Álvarez-Teijeiro S, Urdinguio RG, Fraga MF, Suárez C, García-Pedrero JM.

Sci Rep. 2016 Jan 20;6:19666. doi: 10.1038/srep19666.

32.

Autoregulatory loop of nuclear corepressor 1 expression controls invasion, tumor growth, and metastasis.

Martínez-Iglesias OA, Alonso-Merino E, Gómez-Rey S, Velasco-Martín JP, Martín Orozco R, Luengo E, García Martín R, Ibáñez de Cáceres I, Fernández AF, Fraga MF, González-Peramato P, Varona C, Palacios J, Regadera J, Aranda A.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):E328-37. doi: 10.1073/pnas.1520469113. Epub 2016 Jan 4.

33.

Liver X Receptor Agonist Modifies the DNA Methylation Profile of Synapse and Neurogenesis-Related Genes in the Triple Transgenic Mouse Model of Alzheimer's Disease.

Sandoval-Hernández AG, Hernández HG, Restrepo A, Muñoz JI, Bayon GF, Fernández AF, Fraga MF, Cardona-Gómez GP, Arboleda H, Arboleda GH.

J Mol Neurosci. 2016 Feb;58(2):243-53. doi: 10.1007/s12031-015-0665-8. Epub 2015 Nov 9.

PMID:
26553261
34.

Reprogramming human B cells into induced pluripotent stem cells and its enhancement by C/EBPα.

Bueno C, Sardina JL, Di Stefano B, Romero-Moya D, Muñoz-López A, Ariza L, Chillón MC, Balanzategui A, Castaño J, Herreros A, Fraga MF, Fernández A, Granada I, Quintana-Bustamante O, Segovia JC, Nishimura K, Ohtaka M, Nakanishi M, Graf T, Menendez P.

Leukemia. 2016 Mar;30(3):674-82. doi: 10.1038/leu.2015.294. Epub 2015 Oct 26.

PMID:
26500142
35.

Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development.

Roncero AM, López-Nieva P, Cobos-Fernández MA, Villa-Morales M, González-Sánchez L, López-Lorenzo JL, Llamas P, Ayuso C, Rodríguez-Pinilla SM, Arriba MC, Piris MA, Fernández-Navarro P, Fernández AF, Fraga MF, Santos J, Fernández-Piqueras J.

Leukemia. 2016 Jan;30(1):94-103. doi: 10.1038/leu.2015.202. Epub 2015 Jul 28.

36.

Glypican-1 identifies cancer exosomes and detects early pancreatic cancer.

Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, LeBleu VS, Mittendorf EA, Weitz J, Rahbari N, Reissfelder C, Pilarsky C, Fraga MF, Piwnica-Worms D, Kalluri R.

Nature. 2015 Jul 9;523(7559):177-82. doi: 10.1038/nature14581. Epub 2015 Jun 24.

37.

DNA Methylation Profiling in Pheochromocytoma and Paraganglioma Reveals Diagnostic and Prognostic Markers.

de Cubas AA, Korpershoek E, Inglada-Pérez L, Letouzé E, Currás-Freixes M, Fernández AF, Comino-Méndez I, Schiavi F, Mancikova V, Eisenhofer G, Mannelli M, Opocher G, Timmers H, Beuschlein F, de Krijger R, Cascon A, Rodríguez-Antona C, Fraga MF, Favier J, Gimenez-Roqueplo AP, Robledo M.

Clin Cancer Res. 2015 Jul 1;21(13):3020-30. doi: 10.1158/1078-0432.CCR-14-2804. Epub 2015 Mar 30.

38.

Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer.

Aguilera Ó, González-Sancho JM, Zazo S, Rincón R, Fernández AF, Tapia O, Canals F, Morte B, Calvanese V, Orgaz JL, Niell N, Aguilar S, Freije JM, Graña O, Pisano DG, Borrero A, Martínez-Useros J, Jiménez B, Fraga MF, García-Foncillas J, López-Otín C, Lafarga M, Rojo F, Muñoz A.

Oncotarget. 2015 Mar 20;6(8):5903-17.

39.

Aberrant DNA methylation patterns of spermatozoa in men with unexplained infertility.

Urdinguio RG, Bayón GF, Dmitrijeva M, Toraño EG, Bravo C, Fraga MF, Bassas L, Larriba S, Fernández AF.

Hum Reprod. 2015 May;30(5):1014-28. doi: 10.1093/humrep/dev053. Epub 2015 Mar 9.

PMID:
25753583
40.

DNA methylation patterns in newborns exposed to tobacco in utero.

Ivorra C, Fraga MF, Bayón GF, Fernández AF, Garcia-Vicent C, Chaves FJ, Redon J, Lurbe E.

J Transl Med. 2015 Jan 27;13:25. doi: 10.1186/s12967-015-0384-5.

41.

LINE-1 methylation in granulocyte DNA and trihalomethane exposure is associated with bladder cancer risk.

Salas LA, Villanueva CM, Tajuddin SM, Amaral AF, Fernandez AF, Moore LE, Carrato A, Tardón A, Serra C, García-Closas R, Basagaña X, Rothman N, Silverman DT, Cantor KP, Kogevinas M, Real FX, Fraga MF, Malats N.

Epigenetics. 2014 Nov;9(11):1532-9. doi: 10.4161/15592294.2014.983377.

42.

Methylation of NKG2D ligands contributes to immune system evasion in acute myeloid leukemia.

Baragaño Raneros A, Martín-Palanco V, Fernandez AF, Rodriguez RM, Fraga MF, Lopez-Larrea C, Suarez-Alvarez B.

Genes Immun. 2015 Jan-Feb;16(1):71-82. doi: 10.1038/gene.2014.58. Epub 2014 Nov 13.

PMID:
25393931
43.

H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells.

Fernández AF, Bayón GF, Urdinguio RG, Toraño EG, García MG, Carella A, Petrus-Reurer S, Ferrero C, Martinez-Camblor P, Cubillo I, García-Castro J, Delgado-Calle J, Pérez-Campo FM, Riancho JA, Bueno C, Menéndez P, Mentink A, Mareschi K, Claire F, Fagnani C, Medda E, Toccaceli V, Brescianini S, Moran S, Esteller M, Stolzing A, de Boer J, Nisticò L, Stazi MA, Fraga MF.

Genome Res. 2015 Jan;25(1):27-40. doi: 10.1101/gr.169011.113. Epub 2014 Sep 30.

44.

The epigenetic basis of adaptation and responses to environmental change: perspective on human reproduction.

Fernández AF, Toraño EG, Urdinguio RG, Lana AG, Fernández IA, Fraga MF.

Adv Exp Med Biol. 2014;753:97-117. doi: 10.1007/978-1-4939-0820-2_6. Review.

PMID:
25091908
45.

Regulation of DNA methylation patterns by CK2-mediated phosphorylation of Dnmt3a.

Deplus R, Blanchon L, Rajavelu A, Boukaba A, Defrance M, Luciani J, Rothé F, Dedeurwaerder S, Denis H, Brinkman AB, Simmer F, Müller F, Bertin B, Berdasco M, Putmans P, Calonne E, Litchfield DW, de Launoit Y, Jurkowski TP, Stunnenberg HG, Bock C, Sotiriou C, Fraga MF, Esteller M, Jeltsch A, Fuks F.

Cell Rep. 2014 Aug 7;8(3):743-53. doi: 10.1016/j.celrep.2014.06.048. Epub 2014 Jul 24.

46.

Lineage-restricted function of the pluripotency factor NANOG in stratified epithelia.

Piazzolla D, Palla AR, Pantoja C, Cañamero M, de Castro IP, Ortega S, Gómez-López G, Dominguez O, Megías D, Roncador G, Luque-Garcia JL, Fernandez-Tresguerres B, Fernandez AF, Fraga MF, Rodriguez-Justo M, Manzanares M, Sánchez-Carbayo M, García-Pedrero JM, Rodrigo JP, Malumbres M, Serrano M.

Nat Commun. 2014 Jun 30;5:4226. doi: 10.1038/ncomms5226.

PMID:
24979572
47.

Negative neuronal differentiation of human adipose-derived stem cell clones.

Arribas MI, Ropero AB, Reig JA, Fraga MF, Fernandez AF, Santana A, Roche E.

Regen Med. 2014 May;9(3):279-93. doi: 10.2217/rme.14.11.

PMID:
24935041
48.

Epigenetic alterations in endocrine-related cancer.

Rodríguez-Rodero S, Delgado-Álvarez E, Fernández AF, Fernández-Morera JL, Menéndez-Torre E, Fraga MF.

Endocr Relat Cancer. 2014 Aug;21(4):R319-30. doi: 10.1530/ERC-13-0070. Epub 2014 Jun 4. Review.

49.

Reconstructing the DNA methylation maps of the Neandertal and the Denisovan.

Gokhman D, Lavi E, Prüfer K, Fraga MF, Riancho JA, Kelso J, Pääbo S, Meshorer E, Carmel L.

Science. 2014 May 2;344(6183):523-7. doi: 10.1126/science.1250368. Epub 2014 Apr 17.

50.

Single cell-derived clones from human adipose stem cells present different immunomodulatory properties.

Sempere JM, Martinez-Peinado P, Arribas MI, Reig JA, De La Sen ML, Zubcoff JJ, Fraga MF, Fernández AF, Santana A, Roche E.

Clin Exp Immunol. 2014 May;176(2):255-65. doi: 10.1111/cei.12270.

Supplemental Content

Loading ...
Support Center