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Items: 48

1.

Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors.

Felix J, Weinhäupl K, Chipot C, Dehez F, Hessel A, Gauto DF, Morlot C, Abian O, Gutsche I, Velazquez-Campoy A, Schanda P, Fraga H.

Sci Adv. 2019 Sep 4;5(9):eaaw3818. doi: 10.1126/sciadv.aaw3818. eCollection 2019 Sep.

2.

Aromatic Ring Dynamics, Thermal Activation, and Transient Conformations of a 468 kDa Enzyme by Specific 1H-13C Labeling and Fast Magic-Angle Spinning NMR.

Gauto DF, Macek P, Barducci A, Fraga H, Hessel A, Terauchi T, Gajan D, Miyanoiri Y, Boisbouvier J, Lichtenecker R, Kainosho M, Schanda P.

J Am Chem Soc. 2019 Jul 17;141(28):11183-11195. doi: 10.1021/jacs.9b04219. Epub 2019 Jul 5.

PMID:
31199882
3.

Effect of Thermal Stress on Tissue Ultrastructure and Metabolite Profiles During Initiation of Radiata Pine Somatic Embryogenesis.

Castander-Olarieta A, Montalbán IA, De Medeiros Oliveira E, Dell'Aversana E, D'Amelia L, Carillo P, Steiner N, Fraga HPF, Guerra MP, Goicoa T, Ugarte MD, Pereira C, Moncaleán P.

Front Plant Sci. 2019 Jan 17;9:2004. doi: 10.3389/fpls.2018.02004. eCollection 2018.

4.

Development of high throughput screening methods for inhibitors of ClpC1P1P2 from Mycobacteria tuberculosis.

Fraga H, Rodriguez B, Bardera A, Cid C, Akopian T, Kandror O, Park A, Colmenarejo G, Lelievre J, Goldberg A.

Anal Biochem. 2019 Feb 15;567:30-37. doi: 10.1016/j.ab.2018.12.004. Epub 2018 Dec 10.

5.

The antibiotic cyclomarin blocks arginine-phosphate-induced millisecond dynamics in the N-terminal domain of ClpC1 from Mycobacterium tuberculosis.

Weinhäupl K, Brennich M, Kazmaier U, Lelievre J, Ballell L, Goldberg A, Schanda P, Fraga H.

J Biol Chem. 2018 Jun 1;293(22):8379-8393. doi: 10.1074/jbc.RA118.002251. Epub 2018 Apr 9.

6.

Disulfide driven folding for a conditionally disordered protein.

Fraga H, Pujols J, Gil-Garcia M, Roque A, Bernardo-Seisdedos G, Santambrogio C, Bech-Serra JJ, Canals F, Bernadó P, Grandori R, Millet O, Ventura S.

Sci Rep. 2017 Dec 5;7(1):16994. doi: 10.1038/s41598-017-17259-4.

7.

Solid-State NMR H-N-(C)-H and H-N-C-C 3D/4D Correlation Experiments for Resonance Assignment of Large Proteins.

Fraga H, Arnaud CA, Gauto DF, Audin M, Kurauskas V, Macek P, Krichel C, Guan JY, Boisbouvier J, Sprangers R, Breyton C, Schanda P.

Chemphyschem. 2017 Oct 6;18(19):2697-2703. doi: 10.1002/cphc.201700572. Epub 2017 Sep 5.

8.

Glutathione and abscisic acid supplementation influences somatic embryo maturation and hormone endogenous levels during somatic embryogenesis in Podocarpus lambertii Klotzsch ex Endl.

Fraga HP, Vieira LD, Puttkammer CC, Dos Santos HP, Garighan JA, Guerra MP.

Plant Sci. 2016 Dec;253:98-106. doi: 10.1016/j.plantsci.2016.09.012. Epub 2016 Sep 28.

PMID:
27969001
9.

Modelling climate change impacts on viticultural yield, phenology and stress conditions in Europe.

Fraga H, García de Cortázar Atauri I, Malheiro AC, Santos JA.

Glob Chang Biol. 2016 Nov;22(11):3774-3788. doi: 10.1111/gcb.13382. Epub 2016 Sep 19.

PMID:
27254813
10.

Phylogenetic inference and SSR characterization of tropical woody bamboos tribe Bambuseae (Poaceae: Bambusoideae) based on complete plastid genome sequences.

Vieira Ldo N, Dos Anjos KG, Faoro H, Fraga HP, Greco TM, Pedrosa Fde O, de Souza EM, Rogalski M, de Souza RF, Guerra MP.

Curr Genet. 2016 May;62(2):443-53. doi: 10.1007/s00294-015-0549-z. Epub 2015 Dec 7.

PMID:
26643654
11.

Somatic Embryogenesis in Araucaria angustifolia (Bertol.) Kuntze (Araucariaceae).

Guerra MP, Steiner N, Farias-Soares FL, Vieira Ldo N, Fraga HP, Rogge-Renner GD, Maldonado SB.

Methods Mol Biol. 2016;1359:439-50. doi: 10.1007/978-1-4939-3061-6_24.

PMID:
26619879
12.

Plastid genomics in horticultural species: importance and applications for plant population genetics, evolution, and biotechnology.

Rogalski M, do Nascimento Vieira L, Fraga HP, Guerra MP.

Front Plant Sci. 2015 Jul 30;6:586. doi: 10.3389/fpls.2015.00586. eCollection 2015. Review.

13.

Intradomain Confinement of Disulfides in the Folding of Two Consecutive Modules of the LDL Receptor.

Martínez-Oliván J, Fraga H, Arias-Moreno X, Ventura S, Sancho J.

PLoS One. 2015 Jul 13;10(7):e0132141. doi: 10.1371/journal.pone.0132141. eCollection 2015.

14.

Influence of Cytoplasmatic Folding on Mitochondrial Import.

Fraga H, Ventura S.

Curr Med Chem. 2015;22(19):2349-59. Review.

PMID:
25760085
15.

Integrated analysis of climate, soil, topography and vegetative growth in Iberian viticultural regions.

Fraga H, Malheiro AC, Moutinho-Pereira J, Cardoso RM, Soares PM, Cancela JJ, Pinto JG, Santos JA.

PLoS One. 2014 Sep 24;9(9):e108078. doi: 10.1371/journal.pone.0108078. eCollection 2014.

16.

Association between foldability and aggregation propensity in small disulfide-rich proteins.

Fraga H, Graña-Montes R, Illa R, Covaleda G, Ventura S.

Antioxid Redox Signal. 2014 Jul 20;21(3):368-83. doi: 10.1089/ars.2013.5543. Epub 2014 May 5.

17.

The complete chloroplast genome sequence of Podocarpus lambertii: genome structure, evolutionary aspects, gene content and SSR detection.

Vieira Ldo N, Faoro H, Rogalski M, Fraga HP, Cardoso RL, de Souza EM, de Oliveira Pedrosa F, Nodari RO, Guerra MP.

PLoS One. 2014 Mar 4;9(3):e90618. doi: 10.1371/journal.pone.0090618. eCollection 2014.

18.

The mitochondrial intermembrane space oxireductase Mia40 funnels the oxidative folding pathway of the cytochrome c oxidase assembly protein Cox19.

Fraga H, Bech-Serra JJ, Canals F, Ortega G, Millet O, Ventura S.

J Biol Chem. 2014 Apr 4;289(14):9852-64. doi: 10.1074/jbc.M114.553479. Epub 2014 Feb 25.

19.

An improved protocol for intact chloroplasts and cpDNA isolation in conifers.

Vieira Ldo N, Faoro H, Fraga HP, Rogalski M, de Souza EM, de Oliveira Pedrosa F, Nodari RO, Guerra MP.

PLoS One. 2014 Jan 2;9(1):e84792. doi: 10.1371/journal.pone.0084792. eCollection 2014.

20.

Comparative proteomic analysis of off-type and normal phenotype somatic plantlets derived from somatic embryos of Feijoa (Acca sellowiana (O. Berg) Burret).

Fraga HP, Agapito-Tenfen SZ, Caprestano CA, Nodari RO, Guerra MP.

Plant Sci. 2013 Sep;210:224-31. doi: 10.1016/j.plantsci.2013.06.006. Epub 2013 Jun 18.

PMID:
23849129
21.

Evaluation of the implementation of a quality system in a basic research laboratory: viability and impacts.

Fraga HC, Fukutani KF, Celes FS, Barral AM, Oliveira CI.

Einstein (Sao Paulo). 2012 Oct-Dec;10(4):491-7. English, Portuguese.

22.

Oxidative folding in the mitochondrial intermembrane space in human health and disease.

Fraga H, Ventura S.

Int J Mol Sci. 2013 Jan 30;14(2):2916-27. doi: 10.3390/ijms14022916.

23.

Future scenarios for viticultural zoning in Europe: ensemble projections and uncertainties.

Fraga H, Malheiro AC, Moutinho-Pereira J, Santos JA.

Int J Biometeorol. 2013 Nov;57(6):909-25. doi: 10.1007/s00484-012-0617-8. Epub 2013 Jan 10.

PMID:
23306774
24.

Zinc induced folding is essential for TIM15 activity as an mtHsp70 chaperone.

Fraga H, Papaleo E, Vega S, Velazquez-Campoy A, Ventura S.

Biochim Biophys Acta. 2013 Jan;1830(1):2139-49. doi: 10.1016/j.bbagen.2012.10.002. Epub 2012 Oct 11.

PMID:
23063975
25.

5-Azacytidine combined with 2,4-D improves somatic embryogenesis of Acca sellowiana (O. Berg) Burret by means of changes in global DNA methylation levels.

Fraga HP, Vieira LN, Caprestano CA, Steinmacher DA, Micke GA, Spudeit DA, Pescador R, Guerra MP.

Plant Cell Rep. 2012 Dec;31(12):2165-76. doi: 10.1007/s00299-012-1327-8. Epub 2012 Aug 3.

PMID:
22865112
26.

Protein oxidative folding in the intermembrane mitochondrial space: more than protein trafficking.

Fraga H, Ventura S.

Curr Protein Pept Sci. 2012 May;13(3):224-31. Review.

PMID:
22612783
27.

Enzymatic synthesis of mono and dinucleoside polyphosphates.

Fraga H, Fontes R.

Biochim Biophys Acta. 2011 Dec;1810(12):1195-204. doi: 10.1016/j.bbagen.2011.09.010. Epub 2011 Sep 25. Review.

PMID:
21978831
28.

ATP binds to proteasomal ATPases in pairs with distinct functional effects, implying an ordered reaction cycle.

Smith DM, Fraga H, Reis C, Kafri G, Goldberg AL.

Cell. 2011 Feb 18;144(4):526-38. doi: 10.1016/j.cell.2011.02.005.

29.

FH8--a small EF-hand protein from Fasciola hepatica.

Fraga H, Faria TQ, Pinto F, Almeida A, Brito RM, Damas AM.

FEBS J. 2010 Dec;277(24):5072-85. doi: 10.1111/j.1742-4658.2010.07912.x. Epub 2010 Nov 16.

30.

A laser flash photolysis and theoretical study of hydrogen abstraction from phenols by triplet alpha-naphthoflavone.

de Lucas NC, Fraga HS, Cardoso CP, Corrêa RJ, Garden SJ, Netto-Ferreira JC.

Phys Chem Chem Phys. 2010 Sep 28;12(36):10746-53. doi: 10.1039/c002738c. Epub 2010 Jul 8.

PMID:
20617250
31.

Characterization of rat heart alkaline phosphatase isoenzymes and modulation of activity.

Mota A, Silva P, Neves D, Lemos C, Calhau C, Torres D, Martel F, Fraga H, Ribeiro L, Alçada MN, Pinho MJ, Negrão MR, Pedrosa R, Guerreiro S, Guimarães JT, Azevedo I, Martins MJ.

Braz J Med Biol Res. 2008 Jul;41(7):600-9.

32.

Pyrophosphate and tripolyphosphate affect firefly luciferase luminescence because they act as substrates and not as allosteric effectors.

Fontes R, Fernandes D, Peralta F, Fraga H, Maio I, Esteves da Silva JC.

FEBS J. 2008 Apr;275(7):1500-9. doi: 10.1111/j.1742-4658.2008.06309.x. Epub 2008 Feb 14.

33.

Firefly luminescence: a historical perspective and recent developments.

Fraga H.

Photochem Photobiol Sci. 2008 Feb;7(2):146-58. doi: 10.1039/b719181b. Epub 2008 Jan 23. Review.

PMID:
18264582
34.

Thermostable red and green light-producing firefly luciferase mutants for bioluminescent reporter applications.

Branchini BR, Ablamsky DM, Murtiashaw MH, Uzasci L, Fraga H, Southworth TL.

Anal Biochem. 2007 Feb 15;361(2):253-62. Epub 2006 Nov 21.

PMID:
17181991
35.

Firefly luciferase produces hydrogen peroxide as a coproduct in dehydroluciferyl adenylate formation.

Fraga H, Fernandes D, Novotny J, Fontes R, Esteves da Silva JC.

Chembiochem. 2006 Jun;7(6):929-35.

PMID:
16642538
36.

Coenzyme A affects firefly luciferase luminescence because it acts as a substrate and not as an allosteric effector.

Fraga H, Fernandes D, Fontes R, Esteves da Silva JC.

FEBS J. 2005 Oct;272(20):5206-16.

37.

Synthesis of luciferyl coenzyme A: a bioluminescent substrate for firefly luciferase in the presence of AMP.

Fraga H, Fontes R, Esteves da Silva JC.

Angew Chem Int Ed Engl. 2005 May 30;44(22):3427-9. No abstract available.

PMID:
15861450
38.

Identification of luciferyl adenylate and luciferyl coenzyme a synthesized by firefly luciferase.

Fraga H, Esteves da Silva JC, Fontes R.

Chembiochem. 2004 Jan 3;5(1):110-5.

PMID:
14695520
39.
40.

[Comparative study (in a controlled therapeutic trial) of 3 intermittent regimens, after an initial period of daily administration, in the repeated treatment of pulmonary tuberculosis (results)].

Fraga H, Gomes O, Paz de Almeida A, Gerhardt G, Santiago AC.

Bull Int Union Tuberc. 1973 Jun;48(0):125-38. French. No abstract available.

PMID:
4602467
41.

[Priorities in a modern program of tuberculosis control in countries of Latin America].

Fraga H.

Bull Int Union Tuberc. 1970 Jun;43:37-44. French. No abstract available.

PMID:
5425570
42.

[Medicine and general culture].

Fraga H.

Hospital (Rio J). 1968 Jun;73(6):1847-58. Portuguese. No abstract available.

PMID:
4890405
43.

[Contribution to the study of primary resistance of tuberculosis bacilli to standard drugs in Rio de Janeiro].

FRAGA H, MAGARAO MF, SANTIAGO AC, de ALMEIDA.

Bull Int Union Tuberc. 1962 Jul;32:36-51. French. No abstract available.

PMID:
13894433
44.

The problem of the resistance of M. tuberculosis to standard drugs in Rio de Janeiro, Brazil.

MAGARAO MF, DAUSTER J, SANTIAGO AC, WERNECK E, FRAGA H, ALMEIDA AP, BARRETO RC.

Bibl Tuberc. 1961;16:193-213. No abstract available.

PMID:
13765164
45.

[Tuberculosis hospital. Organization of medical case-book and records. Standardization of methods and classifications].

FRAGA H, de FIGUEIREDO F, MAGARAO MF, CAMPOS AP, TEIXEIRA J, BOAS AV, de ALMEIDA A, MACHADO FILHO JD, BETHLEM N.

Rev Bras Tuberc Doencas Torac. 1960 Jan-Mar;28:11-52. Portuguese. No abstract available.

PMID:
13824297
46.

[Tuberculosis dispensary].

BETHLEM N, BOAS AV, CAMPOS AP, CORDEIRO DS, DE ALMEIDA AP, DE FIGUEIREDO FP, FRAGA H, MACHADO FILHO JD, MAGARAO MF, TEIXEIRA J.

Rev Bras Tuberc Doencas Torac. 1956 Aug;24(172):1041-88. Portuguese. No abstract available.

PMID:
13401099
47.

[Readjustment of programs of the fight against tuberculosis in the face of recent data in phthisiology].

FRAGA H.

Rev Bras Tuberc Doencas Torac. 1956 Mar;24(167):343-8. Portuguese. No abstract available.

PMID:
13336608
48.

Tuberculose e readaptação ao trabalho.

FRAGA H.

J Clin. 1945 Jul;25:247-60. Undetermined Language. No abstract available.

PMID:
21011234

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