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Items: 1 to 50 of 155

1.

Trafficking of siRNA precursors by the dsRBD protein Blanks in Drosophila.

Nitschko V, Kunzelmann S, Fröhlich T, Arnold GJ, Förstemann K.

Nucleic Acids Res. 2020 Feb 6. pii: gkaa072. doi: 10.1093/nar/gkaa072. [Epub ahead of print]

PMID:
32025726
2.

Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy.

Moretti A, Fonteyne L, Giesert F, Hoppmann P, Meier AB, Bozoglu T, Baehr A, Schneider CM, Sinnecker D, Klett K, Fröhlich T, Rahman FA, Haufe T, Sun S, Jurisch V, Kessler B, Hinkel R, Dirschinger R, Martens E, Jilek C, Graf A, Krebs S, Santamaria G, Kurome M, Zakhartchenko V, Campbell B, Voelse K, Wolf A, Ziegler T, Reichert S, Lee S, Flenkenthaler F, Dorn T, Jeremias I, Blum H, Dendorfer A, Schnieke A, Krause S, Walter MC, Klymiuk N, Laugwitz KL, Wolf E, Wurst W, Kupatt C.

Nat Med. 2020 Feb;26(2):207-214. doi: 10.1038/s41591-019-0738-2. Epub 2020 Jan 27.

PMID:
31988462
3.

Detection of collagens by multispectral optoacoustic tomography as an imaging biomarker for Duchenne muscular dystrophy.

Regensburger AP, Fonteyne LM, Jüngert J, Wagner AL, Gerhalter T, Nagel AM, Heiss R, Flenkenthaler F, Qurashi M, Neurath MF, Klymiuk N, Kemter E, Fröhlich T, Uder M, Woelfle J, Rascher W, Trollmann R, Wolf E, Waldner MJ, Knieling F.

Nat Med. 2019 Dec;25(12):1905-1915. doi: 10.1038/s41591-019-0669-y. Epub 2019 Dec 2.

PMID:
31792454
4.

Genetic merit for fertility alters the bovine uterine luminal fluid proteome†.

Gegenfurtner K, Fröhlich T, Flenkenthaler F, Kösters M, Fritz S, Desnoës O, Le Bourhis D, Salvetti P, Sandra O, Charpigny G, Mermillod P, Lonergan P, Wolf E, Arnold GJ.

Biol Reprod. 2020 Mar 13;102(3):730-739. doi: 10.1093/biolre/ioz216.

PMID:
31786596
5.

Downregulation of GRK5 hampers the migration of breast cancer cells.

Sommer AK, Falcenberg M, Ljepoja B, Fröhlich T, Arnold GJ, Wagner E, Roidl A.

Sci Rep. 2019 Oct 29;9(1):15548. doi: 10.1038/s41598-019-51923-1.

6.

Insights into replicative senescence of human testicular peritubular cells.

Schmid N, Flenkenthaler F, Stöckl JB, Dietrich KG, Köhn FM, Schwarzer JU, Kunz L, Luckner M, Wanner G, Arnold GJ, Fröhlich T, Mayerhofer A.

Sci Rep. 2019 Oct 21;9(1):15052. doi: 10.1038/s41598-019-51380-w.

7.

The transmembrane protein LRIG2 increases tumor progression in skin carcinogenesis.

Hoesl C, Fröhlich T, Hundt JE, Kneitz H, Goebeler M, Wolf R, Schneider MR, Dahlhoff M.

Mol Oncol. 2019 Nov;13(11):2476-2492. doi: 10.1002/1878-0261.12579. Epub 2019 Oct 21.

8.

Novel sampling procedure to characterize bovine subclinical endometritis by uterine secretions and tissue.

Helfrich AL, Reichenbach HD, Meyerholz MM, Schoon HA, Arnold GJ, Fröhlich T, Weber F, Zerbe H.

Theriogenology. 2020 Jan 1;141:186-196. doi: 10.1016/j.theriogenology.2019.09.016. Epub 2019 Sep 16.

PMID:
31557616
9.

Does previous application of silver diammine fluoride influence the bond strength of glass ionomer cement and adhesive systems to dentin? Systematic review and meta-analysis.

Fröhlich TT, Rocha RO, Botton G.

Int J Paediatr Dent. 2020 Jan;30(1):85-95. doi: 10.1111/ipd.12571. Epub 2019 Sep 18.

PMID:
31419356
10.

Influence of metabolic status and genetic merit for fertility on proteomic composition of bovine oviduct fluid†.

Gegenfurtner K, Fröhlich T, Kösters M, Mermillod P, Locatelli Y, Fritz S, Salvetti P, Forde N, Lonergan P, Wolf E, Arnold GJ.

Biol Reprod. 2019 Nov 21;101(5):893-905. doi: 10.1093/biolre/ioz142.

PMID:
31347661
11.

APEX2-mediated proximity labeling resolves protein networks in Saccharomyces cerevisiae cells.

Singer-Krüger B, Fröhlich T, Franz-Wachtel M, Nalpas N, Macek B, Jansen RP.

FEBS J. 2020 Jan;287(2):325-344. doi: 10.1111/febs.15007. Epub 2019 Aug 12.

PMID:
31323700
12.

Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus.

Backman M, Flenkenthaler F, Blutke A, Dahlhoff M, Ländström E, Renner S, Philippou-Massier J, Krebs S, Rathkolb B, Prehn C, Grzybek M, Coskun Ü, Rothe M, Adamski J, de Angelis MH, Wanke R, Fröhlich T, Arnold GJ, Blum H, Wolf E.

Mol Metab. 2019 Aug;26:30-44. doi: 10.1016/j.molmet.2019.05.011. Epub 2019 Jun 4.

13.
14.

Temperature Dependence of the Dynamic Parameters of Contact Thermometers.

Augustin S, Fröhlich T.

Sensors (Basel). 2019 May 18;19(10). pii: E2299. doi: 10.3390/s19102299.

15.

A novel approach to study the bovine oviductal fluid proteome using transvaginal endoscopy.

Papp SM, Fröhlich T, Radefeld K, Havlicek V, Kösters M, Yu H, Mayrhofer C, Brem G, Arnold GJ, Besenfelder U.

Theriogenology. 2019 Jul 1;132:53-61. doi: 10.1016/j.theriogenology.2019.04.009. Epub 2019 Apr 8.

PMID:
30991169
16.

Uterine fluid proteome changes during diapause and resumption of embryo development in roe deer (Capreolus capreolus).

van der Weijden VA, Bick JT, Bauersachs S, Arnold GJ, Fröhlich T, Drews B, Ulbrich SE.

Reproduction. 2019 Jul;158(1):13-24. doi: 10.1530/REP-19-0022.

17.

Anti α-enolase antibody is a novel autoimmune biomarker for unexplained recurrent miscarriages.

Ye Y, Kuhn C, Kösters M, Arnold GJ, Ishikawa-Ankerhold H, Schulz C, Rogenhofer N, Thaler CJ, Mahner S, Fröhlich T, Jeschke U, von Schönfeldt V.

EBioMedicine. 2019 Mar;41:610-622. doi: 10.1016/j.ebiom.2019.02.027. Epub 2019 Mar 1.

18.

Necroptosis in primate luteolysis: a role for ceramide.

Bagnjuk K, Stöckl JB, Fröhlich T, Arnold GJ, Behr R, Berg U, Berg D, Kunz L, Bishop C, Xu J, Mayerhofer A.

Cell Death Discov. 2019 Feb 11;5:67. doi: 10.1038/s41420-019-0149-7. eCollection 2019.

19.

Resonant inelastic x-ray incarnation of Young's double-slit experiment.

Revelli A, Moretti Sala M, Monaco G, Becker P, Bohatý L, Hermanns M, Koethe TC, Fröhlich T, Warzanowski P, Lorenz T, Streltsov SV, van Loosdrecht PHM, Khomskii DI, van den Brink J, Grüninger M.

Sci Adv. 2019 Jan 18;5(1):eaav4020. doi: 10.1126/sciadv.aav4020. eCollection 2019 Jan.

20.

Commentary: patient well-being and individual outcomes in the medical practice: impulses from philosophy.

Rüter G, Fröhlich T.

Philos Ethics Humanit Med. 2019 Jan 29;14(1):2. doi: 10.1186/s13010-019-0071-x.

21.

Synthesis of Artemisinin-Estrogen Hybrids Highly Active against HCMV, P. falciparum, and Cervical and Breast Cancer.

Fröhlich T, Kiss A, Wölfling J, Mernyák E, Kulmány ÁE, Minorics R, Zupkó I, Leidenberger M, Friedrich O, Kappes B, Hahn F, Marschall M, Schneider G, Tsogoeva SB.

ACS Med Chem Lett. 2018 Oct 19;9(11):1128-1133. doi: 10.1021/acsmedchemlett.8b00381. eCollection 2018 Nov 8.

22.

CD36-triggered cell invasion and persistent tissue colonization by tumor microvesicles during metastasis.

Pfeiler S, Thakur M, Grünauer P, Megens RTA, Joshi U, Coletti R, Samara V, Müller-Stoy G, Ishikawa-Ankerhold H, Stark K, Klingl A, Fröhlich T, Arnold GJ, Wörmann S, Bruns CJ, Algül H, Weber C, Massberg S, Engelmann B.

FASEB J. 2019 Feb;33(2):1860-1872. doi: 10.1096/fj.201800985R. Epub 2018 Sep 12.

PMID:
30207797
23.

A proteomic analysis of chemoresistance development via sequential treatment with doxorubicin reveals novel players in MCF‑7 breast cancer cells.

Sommer AK, Hermawan A, Ljepoja B, Fröhlich T, Arnold GJ, Wagner E, Roidl A.

Int J Mol Med. 2018 Oct;42(4):1987-1997. doi: 10.3892/ijmm.2018.3781. Epub 2018 Jul 18.

24.

Some thoughts about the terms "centre" and "inside," in relation to the concept of person-centredness.

Fröhlich T.

J Eval Clin Pract. 2018 Oct;24(5):1005-1010. doi: 10.1111/jep.12999. Epub 2018 Jul 30.

PMID:
30058094
25.

Inhibition of Cyclin-Dependent Kinase 5: A Strategy to Improve Sorafenib Response in Hepatocellular Carcinoma Therapy.

Ardelt MA, Fröhlich T, Martini E, Müller M, Kanitz V, Atzberger C, Cantonati P, Meßner M, Posselt L, Lehr T, Wojtyniak JG, Ulrich M, Arnold GJ, König L, Parazzoli D, Zahler S, Rothenfußer S, Mayr D, Gerbes A, Scita G, Vollmar AM, Pachmayr J.

Hepatology. 2019 Jan;69(1):376-393. doi: 10.1002/hep.30190. Epub 2018 Dec 22.

26.

Synthesis of Novel Hybrids of Quinazoline and Artemisinin with High Activities against Plasmodium falciparum, Human Cytomegalovirus, and Leukemia Cells.

Fröhlich T, Reiter C, Ibrahim MM, Beutel J, Hutterer C, Zeitträger I, Bahsi H, Leidenberger M, Friedrich O, Kappes B, Efferth T, Marschall M, Tsogoeva SB.

ACS Omega. 2017 Jun 30;2(6):2422-2431. doi: 10.1021/acsomega.7b00310. Epub 2017 Jun 1.

27.

Synthesis of Thymoquinone-Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents.

Fröhlich T, Reiter C, Saeed MEM, Hutterer C, Hahn F, Leidenberger M, Friedrich O, Kappes B, Marschall M, Efferth T, Tsogoeva SB.

ACS Med Chem Lett. 2017 Dec 21;9(6):534-539. doi: 10.1021/acsmedchemlett.7b00412. eCollection 2018 Jun 14.

28.

Structural and magnetic phase transitions in Cs2[FeCl5(H2O)].

Fröhlich T, Stein J, Bohatý L, Becker P, Gukasov A, Braden M.

J Phys Condens Matter. 2018 Jul 25;30(29):295403. doi: 10.1088/1361-648X/aaca6c. Epub 2018 Jun 5.

PMID:
29869988
29.

Insights into the role of androgen receptor in human testicular peritubular cells.

Mayer C, Adam M, Walenta L, Schmid N, Heikelä H, Schubert K, Flenkenthaler F, Dietrich KG, Gruschka S, Arnold GJ, Fröhlich T, Schwarzer JU, Köhn FM, Strauss L, Welter H, Poutanen M, Mayerhofer A.

Andrology. 2018 Sep;6(5):756-765. doi: 10.1111/andr.12509. Epub 2018 Jun 5.

30.

Characterization of a non-human primate model for the study of testicular peritubular cells-comparison with human testicular peritubular cells.

Schmid N, Stöckl JB, Flenkenthaler F, Dietrich KG, Schwarzer JU, Köhn FM, Drummer C, Fröhlich T, Arnold GJ, Behr R, Mayerhofer A.

Mol Hum Reprod. 2018 Aug 1;24(8):401-410. doi: 10.1093/molehr/gay025.

PMID:
29846669
31.

A proteomic analysis of an in vitro knock-out of miR-200c.

Ljepoja B, García-Roman J, Sommer AK, Fröhlich T, Arnold GJ, Wagner E, Roidl A.

Sci Rep. 2018 May 2;8(1):6927. doi: 10.1038/s41598-018-25240-y.

32.

Treatment of Multidrug-Resistant Leukemia Cells by Novel Artemisinin-, Egonol-, and Thymoquinone-Derived Hybrid Compounds.

Gruber L, Abdelfatah S, Fröhlich T, Reiter C, Klein V, Tsogoeva SB, Efferth T.

Molecules. 2018 Apr 6;23(4). pii: E841. doi: 10.3390/molecules23040841.

33.

Synthesis of Artemisinin-Derived Dimers, Trimers and Dendrimers: Investigation of Their Antimalarial and Antiviral Activities Including Putative Mechanisms of Action.

Fröhlich T, Hahn F, Belmudes L, Leidenberger M, Friedrich O, Kappes B, Couté Y, Marschall M, Tsogoeva SB.

Chemistry. 2018 Jun 7;24(32):8103-8113. doi: 10.1002/chem.201800729. Epub 2018 May 14.

PMID:
29570874
34.

Artesunate-derived monomeric, dimeric and trimeric experimental drugs - Their unique mechanistic basis and pronounced antiherpesviral activity.

Hahn F, Fröhlich T, Frank T, Bertzbach LD, Kohrt S, Kaufer BB, Stamminger T, Tsogoeva SB, Marschall M.

Antiviral Res. 2018 Apr;152:104-110. doi: 10.1016/j.antiviral.2018.02.013. Epub 2018 Feb 16.

PMID:
29458133
35.

ATP-mediated Events in Peritubular Cells Contribute to Sterile Testicular Inflammation.

Walenta L, Fleck D, Fröhlich T, von Eysmondt H, Arnold GJ, Spehr J, Schwarzer JU, Köhn FM, Spehr M, Mayerhofer A.

Sci Rep. 2018 Jan 23;8(1):1431. doi: 10.1038/s41598-018-19624-3.

36.

Control of Chiral Magnetism Through Electric Fields in Multiferroic Compounds above the Long-Range Multiferroic Transition.

Stein J, Baum M, Holbein S, Finger T, Cronert T, Tölzer C, Fröhlich T, Biesenkamp S, Schmalzl K, Steffens P, Lee CH, Braden M.

Phys Rev Lett. 2017 Oct 27;119(17):177201. doi: 10.1103/PhysRevLett.119.177201. Epub 2017 Oct 26.

PMID:
29219446
37.

Total momentum transfer produced by the photons of a multi-pass laser beam as an evident avenue for optical and mass metrology.

Vasilyan S, Fröhlich T, Manske E.

Opt Express. 2017 Aug 21;25(17):20798-20816. doi: 10.1364/OE.25.020798.

PMID:
29041758
38.

Proteomic identification of turkey (Meleagris gallopavo) seminal plasma proteins.

Slowinska M, Nynca J, Arnold GJ, Fröhlich T, Jankowski J, Kozlowski K, Mostek A, Ciereszko A.

Poult Sci. 2017 Sep 1;96(9):3422-3435. doi: 10.3382/ps/pex132.

39.

Antibodies against the mono-methylated arginine-glycine repeat (MMA-RG) of the Epstein-Barr virus nuclear antigen 2 (EBNA2) identify potential cellular proteins targeted in viral transformation.

Ayoubian H, Fröhlich T, Pogodski D, Flatley A, Kremmer E, Schepers A, Feederle R, Arnold GJ, Grässer FA.

J Gen Virol. 2017 Aug;98(8):2128-2142. doi: 10.1099/jgv.0.000870. Epub 2017 Jul 28.

PMID:
28758620
40.

The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes.

Blutke A, Renner S, Flenkenthaler F, Backman M, Haesner S, Kemter E, Ländström E, Braun-Reichhart C, Albl B, Streckel E, Rathkolb B, Prehn C, Palladini A, Grzybek M, Krebs S, Bauersachs S, Bähr A, Brühschwein A, Deeg CA, De Monte E, Dmochewitz M, Eberle C, Emrich D, Fux R, Groth F, Gumbert S, Heitmann A, Hinrichs A, Keßler B, Kurome M, Leipig-Rudolph M, Matiasek K, Öztürk H, Otzdorff C, Reichenbach M, Reichenbach HD, Rieger A, Rieseberg B, Rosati M, Saucedo MN, Schleicher A, Schneider MR, Simmet K, Steinmetz J, Übel N, Zehetmaier P, Jung A, Adamski J, Coskun Ü, Hrabě de Angelis M, Simmet C, Ritzmann M, Meyer-Lindenberg A, Blum H, Arnold GJ, Fröhlich T, Wanke R, Wolf E.

Mol Metab. 2017 Jun 13;6(8):931-940. doi: 10.1016/j.molmet.2017.06.004. eCollection 2017 Aug.

41.

Facile access to potent antiviral quinazoline heterocycles with fluorescence properties via merging metal-free domino reactions.

Held FE, Guryev AA, Fröhlich T, Hampel F, Kahnt A, Hutterer C, Steingruber M, Bahsi H, von Bojničić-Kninski C, Mattes DS, Foertsch TC, Nesterov-Mueller A, Marschall M, Tsogoeva SB.

Nat Commun. 2017 May 2;8:15071. doi: 10.1038/ncomms15071.

42.

Proteomic identification of rainbow trout blood plasma proteins and their relationship to seminal plasma proteins.

Nynca J, Arnold G, Fröhlich T, Ciereszko A.

Proteomics. 2017 Jun;17(11). doi: 10.1002/pmic.201600460.

PMID:
28394474
43.

The Thickness of the Adhesive Layer Increases the Misdiagnosing of the Radiolucent Zones and Restoration Replacement Indication.

Fröhlich TT, Nicoloso GF, Lenzi TL, Soares FZM, De Oliveira Rocha R.

J Esthet Restor Dent. 2017 May 6;29(3):193-200. doi: 10.1111/jerd.12297. Epub 2017 Mar 17.

PMID:
28304128
44.

Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD).

Kemter E, Fröhlich T, Arnold GJ, Wolf E, Wanke R.

Sci Rep. 2017 Feb 21;7:42970. doi: 10.1038/srep42970.

45.

Synthesis of Novel Hybrids of Thymoquinone and Artemisinin with High Activity and Selectivity Against Colon Cancer.

Fröhlich T, Ndreshkjana B, Muenzner JK, Reiter C, Hofmeister E, Mederer S, Fatfat M, El-Baba C, Gali-Muhtasib H, Schneider-Stock R, Tsogoeva SB.

ChemMedChem. 2017 Feb 3;12(3):226-234. doi: 10.1002/cmdc.201600594. Epub 2017 Jan 11.

PMID:
27973725
46.

ADNP Is a Therapeutically Inducible Repressor of WNT Signaling in Colorectal Cancer.

Blaj C, Bringmann A, Schmidt EM, Urbischek M, Lamprecht S, Fröhlich T, Arnold GJ, Krebs S, Blum H, Hermeking H, Jung A, Kirchner T, Horst D.

Clin Cancer Res. 2017 Jun 1;23(11):2769-2780. doi: 10.1158/1078-0432.CCR-16-1604. Epub 2016 Nov 30.

47.

ROS-Mediated Inhibition of S-nitrosoglutathione Reductase Contributes to the Activation of Anti-oxidative Mechanisms.

Kovacs I, Holzmeister C, Wirtz M, Geerlof A, Fröhlich T, Römling G, Kuruthukulangarakoola GT, Linster E, Hell R, Arnold GJ, Durner J, Lindermayr C.

Front Plant Sci. 2016 Nov 10;7:1669. eCollection 2016.

48.

Improved cryotolerance and developmental potential of in vitro and in vivo matured mouse oocytes by supplementing with a glutathione donor prior to vitrification.

Trapphoff T, Heiligentag M, Simon J, Staubach N, Seidel T, Otte K, Fröhlich T, Arnold GJ, Eichenlaub-Ritter U.

Mol Hum Reprod. 2016 Dec;22(12):867-881. Epub 2016 Sep 7.

PMID:
27604460
49.

In Vivo and In Vitro Optimization of Screening Antimalarial Hits toward Lead Molecules for Preclinical Development.

Fröhlich T, Tsogoeva SB.

J Med Chem. 2016 Nov 10;59(21):9668-9671. Epub 2016 Oct 24.

PMID:
27775354
50.

Modelling oviduct fluid formation in vitro.

Simintiras CA, Fröhlich T, Sathyapalan T, Arnold GJ, Ulbrich SE, Leese HJ, Sturmey RG.

Reproduction. 2016 Oct 13. pii: REP-15-0508. [Epub ahead of print]

PMID:
27738189

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