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Best matches for Frère JM[au]:

1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases. Sevaille L et al. ChemMedChem. (2017)

From "An Enzyme Able to Destroy Penicillin" to Carbapenemases: 70 Years of Beta-lactamase Misbehaviour. Frère JM et al. Curr Drug Targets. (2016)

Penicillin-binding proteins: evergreen drug targets. Frère JM et al. Curr Opin Pharmacol. (2014)

Search results

Items: 1 to 50 of 390

1.

Kinetic analysis of N-alkylaryl carboxamide hexitol nucleotides as substrates for evolved polymerases.

Renders M, Dumbre S, Abramov M, Kestemont D, Margamuljana L, Largy E, Cozens C, Vandenameele J, Pinheiro VB, Toye D, Frère JM, Herdewijn P.

Nucleic Acids Res. 2019 Mar 18;47(5):2160-2168. doi: 10.1093/nar/gkz008.

2.

1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases.

Sevaille L, Gavara L, Bebrone C, De Luca F, Nauton L, Achard M, Mercuri P, Tanfoni S, Borgianni L, Guyon C, Lonjon P, Turan-Zitouni G, Dzieciolowski J, Becker K, Bénard L, Condon C, Maillard L, Martinez J, Frère JM, Dideberg O, Galleni M, Docquier JD, Hernandez JF.

ChemMedChem. 2017 Jun 21;12(12):972-985. doi: 10.1002/cmdc.201700186. Epub 2017 Jun 12.

PMID:
28505394
3.

Interaction of Avibactam with Class B Metallo-β-Lactamases.

Abboud MI, Damblon C, Brem J, Smargiasso N, Mercuri P, Gilbert B, Rydzik AM, Claridge TD, Schofield CJ, Frère JM.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):5655-62. doi: 10.1128/AAC.00897-16. Print 2016 Oct.

4.

The CebE/MsiK Transporter is a Doorway to the Cello-oligosaccharide-mediated Induction of Streptomyces scabies Pathogenicity.

Jourdan S, Francis IM, Kim MJ, Salazar JJ, Planckaert S, Frère JM, Matagne A, Kerff F, Devreese B, Loria R, Rigali S.

Sci Rep. 2016 Jun 2;6:27144. doi: 10.1038/srep27144.

5.

Kinetics of the Interaction between BAL29880 and LK157 and the Class C β-Lactamase CHE-1.

Fernea A, Galleni M, Frère JM.

Antimicrob Agents Chemother. 2016 Jan 4;60(3):1747-50. doi: 10.1128/AAC.02062-15.

6.

Analysis of the Structure and Function of FOX-4 Cephamycinase.

Lefurgy ST, Malashkevich VN, Aguilan JT, Nieves E, Mundorff EC, Biju B, Noel MA, Toro R, Baiwir D, Papp-Wallace KM, Almo SC, Frere JM, Bou G, Bonomo RA.

Antimicrob Agents Chemother. 2015 Nov 2;60(2):717-28. doi: 10.1128/AAC.01887-15. Print 2016 Feb.

7.

From "An Enzyme Able to Destroy Penicillin" to Carbapenemases: 70 Years of Beta-lactamase Misbehaviour.

Frère JM, Sauvage E, Kerff F.

Curr Drug Targets. 2016;17(9):974-82. Review.

PMID:
26424390
8.

Penicillin-binding proteins: evergreen drug targets.

Frère JM, Page MG.

Curr Opin Pharmacol. 2014 Oct;18:112-9. doi: 10.1016/j.coph.2014.09.012. Epub 2014 Oct 14. Review.

PMID:
25450065
9.

Kinetics of the interaction between avibactam and the CHE-1 class C β-lactamase.

Fernea A, Galleni M, Frère JM.

J Antimicrob Chemother. 2015 Mar;70(3):951-3. doi: 10.1093/jac/dku442. Epub 2014 Oct 31. No abstract available.

PMID:
25362576
10.

The proline-rich motif of the proDer p 3 allergen propeptide is crucial for protease-protease interaction.

Dumez ME, Herman J, Campisi V, Bouaziz A, Rosu F, Luxen A, Vandenberghe I, de Pauw E, Frère JM, Matagne A, Chevigné A, Galleni M.

PLoS One. 2013 Sep 20;8(9):e68014. doi: 10.1371/journal.pone.0068014. eCollection 2013.

11.

Activity of ceftaroline against Enterococcus faecium PBP5.

Henry X, Verlaine O, Amoroso A, Coyette J, Frère JM, Joris B.

Antimicrob Agents Chemother. 2013 Dec;57(12):6358-60. doi: 10.1128/AAC.00923-13. Epub 2013 Sep 23.

12.

Covalent trapping and bacterial resistance to ceftazidime.

Frère JM.

J Biol Chem. 2013 Sep 13;288(37):26967. doi: 10.1074/jbc.L113.493676. No abstract available.

13.

Inhibition of Streptococcus pneumoniae penicillin-binding protein 2x and Actinomadura R39 DD-peptidase activities by ceftaroline.

Zervosen A, Zapun A, Frère JM.

Antimicrob Agents Chemother. 2013 Jan;57(1):661-3. doi: 10.1128/AAC.01593-12. Epub 2012 Nov 12.

14.

Development of new drugs for an old target: the penicillin binding proteins.

Zervosen A, Sauvage E, Frère JM, Charlier P, Luxen A.

Molecules. 2012 Oct 24;17(11):12478-505. doi: 10.3390/molecules171112478. Review.

15.

Inhibition of a cold-active alkaline phosphatase by imipenem revealed by in silico modeling of metallo-β-lactamase active sites.

Chakraborty S, Asgeirsson B, Minda R, Salaye L, Frère JM, Rao BJ.

FEBS Lett. 2012 Oct 19;586(20):3710-5. doi: 10.1016/j.febslet.2012.08.030. Epub 2012 Sep 11.

16.

Synthesis, crystal structures and electronic properties of isomers of chloro-pyridinylvinyl-1H-indoles.

Moineaux L, Laurent S, Reniers J, Dolušić E, Galleni M, Frère JM, Masereel B, Frédérick R, Wouters J.

Eur J Med Chem. 2012 Aug;54:95-102. doi: 10.1016/j.ejmech.2012.04.033. Epub 2012 May 3.

PMID:
22626654
17.

The CphAII protein from Aquifex aeolicus exhibits a metal-dependent phosphodiesterase activity.

Kupper M, Bauvois C, Frère JM, Hoffmann K, Galleni M, Bebrone C.

Extremophiles. 2012 Jan;16(1):45-55. doi: 10.1007/s00792-011-0404-1. Epub 2011 Oct 19.

18.

Comparative functional analysis of the human macrophage chitotriosidase.

Vandevenne M, Campisi V, Freichels A, Gillard C, Gaspard G, Frère JM, Galleni M, Filée P.

Protein Sci. 2011 Aug;20(8):1451-63. doi: 10.1002/pro.676.

19.

Effects of monopropanediamino-β-cyclodextrin on the denaturation process of the hybrid protein BlaPChBD.

Vandevenne M, Gaspard G, Belgsir el M, Ramnath M, Cenatiempo Y, Marechal D, Dumoulin M, Frere JM, Matagne A, Galleni M, Filee P.

Biochim Biophys Acta. 2011 Sep;1814(9):1146-53. doi: 10.1016/j.bbapap.2011.05.007. Epub 2011 May 15.

20.

Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin-binding protein.

Zervosen A, Herman R, Kerff F, Herman A, Bouillez A, Prati F, Pratt RF, Frère JM, Joris B, Luxen A, Charlier P, Sauvage E.

J Am Chem Soc. 2011 Jul 20;133(28):10839-48. doi: 10.1021/ja200696y. Epub 2011 Jun 24.

21.

Discovery and preliminary SARs of keto-indoles as novel indoleamine 2,3-dioxygenase (IDO) inhibitors.

Dolušić E, Larrieu P, Blanc S, Sapunaric F, Pouyez J, Moineaux L, Colette D, Stroobant V, Pilotte L, Colau D, Ferain T, Fraser G, Galleni M, Frère JM, Masereel B, Van den Eynde B, Wouters J, Frédérick R.

Eur J Med Chem. 2011 Jul;46(7):3058-65. doi: 10.1016/j.ejmech.2011.02.049. Epub 2011 Feb 26.

22.

Small molecule inhibitors of peptidoglycan synthesis targeting the lipid II precursor.

Derouaux A, Turk S, Olrichs NK, Gobec S, Breukink E, Amoroso A, Offant J, Bostock J, Mariner K, Chopra I, Vernet T, Zervosen A, Joris B, Frère JM, Nguyen-Distèche M, Terrak M.

Biochem Pharmacol. 2011 May 1;81(9):1098-105. doi: 10.1016/j.bcp.2011.02.008. Epub 2011 Feb 26.

PMID:
21356201
23.

Broad antibiotic resistance profile of the subclass B3 metallo-β-lactamase GOB-1, a di-zinc enzyme.

Horsfall LE, Izougarhane Y, Lassaux P, Selevsek N, Liénard BM, Poirel L, Kupper MB, Hoffmann KM, Frère JM, Galleni M, Bebrone C.

FEBS J. 2011 Apr;278(8):1252-63. doi: 10.1111/j.1742-4658.2011.08046.x. Epub 2011 Mar 4.

24.

Indol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors.

Dolušić E, Larrieu P, Blanc S, Sapunaric F, Norberg B, Moineaux L, Colette D, Stroobant V, Pilotte L, Colau D, Ferain T, Fraser G, Galleni M, Frère JM, Masereel B, Van den Eynde B, Wouters J, Frédérick R.

Bioorg Med Chem. 2011 Feb 15;19(4):1550-61. doi: 10.1016/j.bmc.2010.12.032. Epub 2010 Dec 16. Erratum in: Bioorg Med Chem. 2011 May 1;19(9):3029. Galeni, Moreno [corrected to Galleni, Moreno].

25.

Biochemical and structural characterization of the subclass B1 metallo-β-lactamase VIM-4.

Lassaux P, Traoré DA, Loisel E, Favier A, Docquier JD, Sohier JS, Laurent C, Bebrone C, Frère JM, Ferrer JL, Galleni M.

Antimicrob Agents Chemother. 2011 Mar;55(3):1248-55. doi: 10.1128/AAC.01486-09. Epub 2010 Dec 13.

26.

Three factors that modulate the activity of class D β-lactamases and interfere with the post-translational carboxylation of Lys70.

Vercheval L, Bauvois C, di Paolo A, Borel F, Ferrer JL, Sauvage E, Matagne A, Frère JM, Charlier P, Galleni M, Kerff F.

Biochem J. 2010 Dec 15;432(3):495-504. doi: 10.1042/BJ20101122.

PMID:
21108605
27.

Novel peptide inhibiting both TEM-1 β-lactamase and penicillin-binding proteins.

Phichith D, Bun S, Padiolleau-Lefevre S, Guellier A, Banh S, Galleni M, Frere JM, Thomas D, Friboulet A, Avalle B.

FEBS J. 2010 Dec;277(23):4965-72. doi: 10.1111/j.1742-4658.2010.07906.x. Epub 2010 Nov 2.

28.

Mechanistic studies of the inactivation of TEM-1 and P99 by NXL104, a novel non-beta-lactam beta-lactamase inhibitor.

Stachyra T, Péchereau MC, Bruneau JM, Claudon M, Frère JM, Miossec C, Coleman K, Black MT.

Antimicrob Agents Chemother. 2010 Dec;54(12):5132-8. doi: 10.1128/AAC.00568-10. Epub 2010 Oct 4.

29.

1,6-AnhMurNAc derivatives for assay development of amidase AmiD.

Mercier F, Zervosen A, Teller N, Frère JM, Herman R, Pennartz A, Joris B, Luxen A.

Bioorg Med Chem. 2010 Nov 1;18(21):7422-31. doi: 10.1016/j.bmc.2010.09.010. Epub 2010 Sep 8.

PMID:
20889346
30.

NH-1,2,3-Triazole-based Inhibitors of the VIM-2 Metallo-β-Lactamase: Synthesis and Structure-Activity Studies.

Weide T, Saldanha SA, Minond D, Spicer TP, Fotsing JR, Spaargaren M, Frère JM, Bebrone C, Sharpless KB, Hodder PS, Fokin VV.

ACS Med Chem Lett. 2010 Jul 8;1(4):150-154.

31.

Mercaptophosphonate compounds as broad-spectrum inhibitors of the metallo-beta-lactamases.

Lassaux P, Hamel M, Gulea M, Delbrück H, Mercuri PS, Horsfall L, Dehareng D, Kupper M, Frère JM, Hoffmann K, Galleni M, Bebrone C.

J Med Chem. 2010 Jul 8;53(13):4862-76. doi: 10.1021/jm100213c.

PMID:
20527888
32.

Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding.

Borgianni L, Vandenameele J, Matagne A, Bini L, Bonomo RA, Frère JM, Rossolini GM, Docquier JD.

Antimicrob Agents Chemother. 2010 Aug;54(8):3197-204. doi: 10.1128/AAC.01336-09. Epub 2010 May 24.

33.

Folding of class A beta-lactamases is rate-limited by peptide bond isomerization and occurs via parallel pathways.

Vandenameele J, Lejeune A, Di Paolo A, Brans A, Frère JM, Schmid FX, Matagne A.

Biochemistry. 2010 May 18;49(19):4264-75. doi: 10.1021/bi100369d.

PMID:
20384356
34.

Specific structural features of the N-acetylmuramoyl-L-alanine amidase AmiD from Escherichia coli and mechanistic implications for enzymes of this family.

Kerff F, Petrella S, Mercier F, Sauvage E, Herman R, Pennartz A, Zervosen A, Luxen A, Frère JM, Joris B, Charlier P.

J Mol Biol. 2010 Mar 19;397(1):249-59. doi: 10.1016/j.jmb.2009.12.038. Epub 2009 Dec 28.

PMID:
20036252
35.

Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases.

Baurin S, Vercheval L, Bouillenne F, Falzone C, Brans A, Jacquamet L, Ferrer JL, Sauvage E, Dehareng D, Frère JM, Charlier P, Galleni M, Kerff F.

Biochemistry. 2009 Dec 1;48(47):11252-63. doi: 10.1021/bi901548c.

PMID:
19860471
36.

Ir-CPI, a coagulation contact phase inhibitor from the tick Ixodes ricinus, inhibits thrombus formation without impairing hemostasis.

Decrem Y, Rath G, Blasioli V, Cauchie P, Robert S, Beaufays J, Frère JM, Feron O, Dogné JM, Dessy C, Vanhamme L, Godfroid E.

J Exp Med. 2009 Oct 26;206(11):2381-95. doi: 10.1084/jem.20091007. Epub 2009 Oct 5.

37.

Characterization of the proteins encoded by the Bacillus subtilis yoxA-dacC operon.

Duez C, Zervosen A, Teller N, Melkonian R, Banzubazé E, Bouillenne F, Luxen A, Frère JM.

FEMS Microbiol Lett. 2009 Nov;300(1):42-7. doi: 10.1111/j.1574-6968.2009.01761.x. Epub 2009 Aug 18.

38.

Positively cooperative binding of zinc ions to Bacillus cereus 569/H/9 beta-lactamase II suggests that the binuclear enzyme is the only relevant form for catalysis.

Jacquin O, Balbeur D, Damblon C, Marchot P, De Pauw E, Roberts GC, Frère JM, Matagne A.

J Mol Biol. 2009 Oct 9;392(5):1278-91. doi: 10.1016/j.jmb.2009.07.092. Epub 2009 Aug 6.

PMID:
19665032
39.

IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso.

Zeba B, De Luca F, Dubus A, Delmarcelle M, Simporé J, Nacoulma OG, Rossolini GM, Frère JM, Docquier JD.

Antimicrob Agents Chemother. 2009 Oct;53(10):4320-6. doi: 10.1128/AAC.01607-08. Epub 2009 Aug 3.

40.

The structure of the dizinc subclass B2 metallo-beta-lactamase CphA reveals that the second inhibitory zinc ion binds in the histidine site.

Bebrone C, Delbrück H, Kupper MB, Schlömer P, Willmann C, Frère JM, Fischer R, Galleni M, Hoffmann KM.

Antimicrob Agents Chemother. 2009 Oct;53(10):4464-71. doi: 10.1128/AAC.00288-09. Epub 2009 Aug 3.

41.

Creating hybrid proteins by insertion of exogenous peptides into permissive sites of a class A beta-lactamase.

Ruth N, Quinting B, Mainil J, Hallet B, Frère JM, Huygen K, Galleni M.

FEBS J. 2008 Oct;275(20):5150-60. doi: 10.1111/j.1742-4658.2008.06646.x. Epub 2008 Sep 11.

42.

Activation mechanism of recombinant Der p 3 allergen zymogen: contribution of cysteine protease Der p 1 and effect of propeptide glycosylation.

Dumez ME, Teller N, Mercier F, Tanaka T, Vandenberghe I, Vandenbranden M, Devreese B, Luxen A, Frère JM, Matagne A, Jacquet A, Galleni M, Chevigné A.

J Biol Chem. 2008 Nov 7;283(45):30606-17. doi: 10.1074/jbc.M803041200. Epub 2008 Aug 25.

43.

Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols.

Liénard BM, Garau G, Horsfall L, Karsisiotis AI, Damblon C, Lassaux P, Papamicael C, Roberts GC, Galleni M, Dideberg O, Frère JM, Schofield CJ.

Org Biomol Chem. 2008 Jul 7;6(13):2282-94. doi: 10.1039/b802311e. Epub 2008 May 7.

PMID:
18563261
44.

Mutational analysis of the zinc- and substrate-binding sites in the CphA metallo-beta-lactamase from Aeromonas hydrophila.

Bebrone C, Anne C, Kerff F, Garau G, De Vriendt K, Lantin R, Devreese B, Van Beeumen J, Dideberg O, Frère JM, Galleni M.

Biochem J. 2008 Aug 15;414(1):151-9. doi: 10.1042/BJ20080375.

45.

Rapid and easy development of versatile tools to study protein/ligand interactions.

Vandevenne M, Gaspard G, Yilmaz N, Giannotta F, Frère JM, Galleni M, Filée P.

Protein Eng Des Sel. 2008 Jul;21(7):443-51. doi: 10.1093/protein/gzn021. Epub 2008 May 2.

46.

Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora.

Stoczko M, Frère JM, Rossolini GM, Docquier JD.

Antimicrob Agents Chemother. 2008 Jul;52(7):2473-9. doi: 10.1128/AAC.01062-07. Epub 2008 Apr 28.

47.

Crystal structure of a cold-adapted class C beta-lactamase.

Michaux C, Massant J, Kerff F, Frère JM, Docquier JD, Vandenberghe I, Samyn B, Pierrard A, Feller G, Charlier P, Van Beeumen J, Wouters J.

FEBS J. 2008 Apr;275(8):1687-97. doi: 10.1111/j.1742-4658.2008.06324.x. Epub 2008 Feb 29.

48.

Penicillin-binding protein 2x of Streptococcus pneumoniae: three new mutational pathways for remodelling an essential enzyme into a resistance determinant.

Maurer P, Koch B, Zerfass I, Krauss J, van der Linden M, Frère JM, Contreras-Martel C, Hakenbeck R.

J Mol Biol. 2008 Mar 7;376(5):1403-16. doi: 10.1016/j.jmb.2007.12.058. Epub 2008 Jan 4.

PMID:
18234221
49.

Treatment of health-care-associated infections caused by Gram-negative bacteria: a consensus statement.

Chopra I, Schofield C, Everett M, O'Neill A, Miller K, Wilcox M, Frère JM, Dawson M, Czaplewski L, Urleb U, Courvalin P.

Lancet Infect Dis. 2008 Feb;8(2):133-9. doi: 10.1016/S1473-3099(08)70018-5.

PMID:
18222164
50.

Dynamic combinatorial mass spectrometry leads to metallo-beta-lactamase inhibitors.

Liénard BM, Hüting R, Lassaux P, Galleni M, Frère JM, Schofield CJ.

J Med Chem. 2008 Feb 14;51(3):684-8. doi: 10.1021/jm070866g. Epub 2008 Jan 19.

PMID:
18205296

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