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Items: 27

1.

Follicular Helper T Cells Are Major Human Immunodeficiency Virus-2 Reservoirs and Support Productive Infection.

Godinho-Santos A, Foxall RB, Antão AV, Tavares B, Ferreira T, Serra-Caetano A, Matoso P, Sousa AE.

J Infect Dis. 2020 Jan 1;221(1):122-126. doi: 10.1093/infdis/jiz431.

2.

Cyclophosphamide Enhances Cancer Antibody Immunotherapy in the Resistant Bone Marrow Niche by Modulating Macrophage FcγR Expression.

Roghanian A, Hu G, Fraser C, Singh M, Foxall RB, Meyer MJ, Lees E, Huet H, Glennie MJ, Beers SA, Lim SH, Ashton-Key M, Thirdborough SM, Cragg MS, Chen J.

Cancer Immunol Res. 2019 Nov;7(11):1876-1890. doi: 10.1158/2326-6066.CIR-18-0835. Epub 2019 Aug 26.

PMID:
31451483
3.

HIV-2 infection is associated with preserved GALT homeostasis and epithelial integrity despite ongoing mucosal viral replication.

Fernandes SM, Pires AR, Matoso P, Ferreira C, Nunes-Cabaço H, Correia L, Valadas E, Poças J, Pacheco P, Veiga-Fernandes H, Foxall RB, Sousa AE.

Mucosal Immunol. 2018 Jan;11(1):236-248. doi: 10.1038/mi.2017.44. Epub 2017 May 17.

PMID:
28513595
4.

miRNA profiling of human naive CD4 T cells links miR-34c-5p to cell activation and HIV replication.

Amaral AJ, Andrade J, Foxall RB, Matoso P, Matos AM, Soares RS, Rocha C, Ramos CG, Tendeiro R, Serra-Caetano A, Guerra-Assunção JA, Santa-Marta M, Gonçalves J, Gama-Carvalho M, Sousa AE.

EMBO J. 2017 Feb 1;36(3):346-360. doi: 10.15252/embj.201694335. Epub 2016 Dec 19.

5.

Human naïve regulatory T-cells feature high steady-state turnover and are maintained by IL-7.

Silva SL, Albuquerque AS, Serra-Caetano A, Foxall RB, Pires AR, Matoso P, Fernandes SM, Ferreira J, Cheynier R, Victorino RM, Caramalho I, Barata JT, Sousa AE.

Oncotarget. 2016 Mar 15;7(11):12163-75. doi: 10.18632/oncotarget.7512.

6.

Regulatory T-Cell Development in the Human Thymus.

Caramalho Í, Nunes-Cabaço H, Foxall RB, Sousa AE.

Front Immunol. 2015 Aug 3;6:395. doi: 10.3389/fimmu.2015.00395. eCollection 2015. Review.

7.

Human regulatory T-cell development is dictated by Interleukin-2 and -15 expressed in a non-overlapping pattern in the thymus.

Caramalho I, Nunes-Silva V, Pires AR, Mota C, Pinto AI, Nunes-Cabaço H, Foxall RB, Sousa AE.

J Autoimmun. 2015 Jan;56:98-110. doi: 10.1016/j.jaut.2014.11.002. Epub 2014 Dec 4.

PMID:
25481744
8.

Thymic HIV-2 infection uncovers posttranscriptional control of viral replication in human thymocytes.

Nunes-Cabaço H, Matoso P, Foxall RB, Tendeiro R, Pires AR, Carvalho T, Pinheiro AI, Soares RS, Sousa AE.

J Virol. 2015 Feb;89(4):2201-8. doi: 10.1128/JVI.03047-14. Epub 2014 Dec 3.

9.

Massive hypereosinophilia and vasculitis associated with major expansion of interleukin-5-producing CD8+ T cells in HIV-1 infection.

Jorge I, Amaral B, Soares-Almeida LM, Foxall RB, Tendeiro R, Santos JM, Sousa AE, Victorino RM.

AIDS. 2014 Apr 24;28(7):1075-7. doi: 10.1097/QAD.0000000000000205. No abstract available.

PMID:
24685745
10.

Enteric mucosa integrity in the presence of a preserved innate interleukin 22 compartment in HIV type 1-treated individuals.

Fernandes SM, Pires AR, Ferreira C, Foxall RB, Rino J, Santos C, Correia L, Poças J, Veiga-Fernandes H, Sousa AE.

J Infect Dis. 2014 Aug 15;210(4):630-40. doi: 10.1093/infdis/jiu126. Epub 2014 Mar 5.

PMID:
24604817
11.

Monocyte and myeloid dendritic cell activation occurs throughout HIV type 2 infection, an attenuated form of HIV disease.

Cavaleiro R, Tendeiro R, Foxall RB, Soares RS, Baptista AP, Gomes P, Valadas E, Victorino RM, Sousa AE.

J Infect Dis. 2013 Jun 1;207(11):1730-42. doi: 10.1093/infdis/jit085. Epub 2013 Mar 4.

PMID:
23460749
12.

Preserved CD4 T-cell telomere length during long-lasting HIV-2 infection.

Tendeiro R, Albuquerque AS, Foxall RB, Cavaleiro R, Soares RS, Baptista AP, Soares MV, Gomes P, Sousa AE.

AIDS. 2013 Jan 14;27(2):289-92. doi: 10.1097/QAD.0b013e32835ab234.

PMID:
23032416
13.

Memory B-cell depletion is a feature of HIV-2 infection even in the absence of detectable viremia.

Tendeiro R, Fernandes S, Foxall RB, Marcelino JM, Taveira N, Soares RS, Baptista AP, Cavaleiro R, Gomes P, Victorino RM, Sousa AE.

AIDS. 2012 Aug 24;26(13):1607-17.

PMID:
22695303
14.

PD-1 and its ligand PD-L1 are progressively up-regulated on CD4 and CD8 T-cells in HIV-2 infection irrespective of the presence of viremia.

Tendeiro R, Foxall RB, Baptista AP, Pinto F, Soares RS, Cavaleiro R, Valadas E, Gomes P, Victorino RM, Sousa AE.

AIDS. 2012 Jun 1;26(9):1065-71. doi: 10.1097/QAD.0b013e32835374db.

PMID:
22441249
15.

Memory and naive-like regulatory CD4+ T cells expand during HIV-2 infection in direct association with CD4+ T-cell depletion irrespectively of viremia.

Foxall RB, Albuquerque AS, Soares RS, Baptista AP, Cavaleiro R, Tendeiro R, Gomes P, Victorino RM, Sousa AE.

AIDS. 2011 Oct 23;25(16):1961-70. doi: 10.1097/QAD.0b013e32834b3554.

PMID:
21811143
16.

Cell-associated viral burden provides evidence of ongoing viral replication in aviremic HIV-2-infected patients.

Soares RS, Tendeiro R, Foxall RB, Baptista AP, Cavaleiro R, Gomes P, Camacho R, Valadas E, Doroana M, Lucas M, Antunes F, Victorino RM, Sousa AE.

J Virol. 2011 Mar;85(5):2429-38. doi: 10.1128/JVI.01921-10. Epub 2010 Dec 15.

17.

Major depletion of plasmacytoid dendritic cells in HIV-2 infection, an attenuated form of HIV disease.

Cavaleiro R, Baptista AP, Soares RS, Tendeiro R, Foxall RB, Gomes P, Victorino RM, Sousa AE.

PLoS Pathog. 2009 Nov;5(11):e1000667. doi: 10.1371/journal.ppat.1000667. Epub 2009 Nov 20.

18.

Dendritic cell differentiation and maturation in the presence of HIV type 2 envelope.

Cavaleiro R, Baptista AP, Foxall RB, Victorino RM, Sousa AE.

AIDS Res Hum Retroviruses. 2009 Apr;25(4):425-31. doi: 10.1089/aid.2008.0247.

PMID:
19320568
19.

Gag-specific CD4+ T-cell frequency is inversely correlated with proviral load and directly correlated with immune activation in infection with human immunodeficiency virus type 2 (HIV-2) but not HIV-1.

Foxall RB, Cortesão CS, Albuquerque AS, Soares RS, Victorino RM, Sousa AE.

J Virol. 2008 Oct;82(19):9795-9. doi: 10.1128/JVI.01217-08. Epub 2008 Jul 23.

20.

Increased frequency of CD25dimCD4+ T-cells in HIV-2 infection, a naturally occurring attenuated form of HIV-1.

Foxall RB, Soares RS, Albuquerque AS, Cortesão CS, Victorino RM, Sousa AE.

Clin Immunol. 2008 May;127(2):158-67. doi: 10.1016/j.clim.2008.01.008. Epub 2008 Mar 3.

PMID:
18313362
21.

Low CD4 T-cell counts despite low levels of circulating HIV: insights from the comparison of HIV-1 infected patients with a discordant response to antiretroviral therapy to patients with untreated advanced HIV-2 disease.

Albuquerque AS, Foxall RB, Cortesão CS, Soares RS, Doroana M, Ribeiro A, Lucas M, Antunes F, Victorino RM, Sousa AE.

Clin Immunol. 2007 Oct;125(1):67-75. Epub 2007 Aug 9.

PMID:
17692571
22.
23.

Heterologous cells cooperate to augment stem cell migration, homing, and engraftment.

Adams GB, Chabner KT, Foxall RB, Weibrecht KW, Rodrigues NP, Dombkowski D, Fallon R, Poznansky MC, Scadden DT.

Blood. 2003 Jan 1;101(1):45-51. Epub 2002 Aug 22.

PMID:
12393569
24.

Thymocyte emigration is mediated by active movement away from stroma-derived factors.

Poznansky MC, Olszak IT, Evans RH, Wang Z, Foxall RB, Olson DP, Weibrecht K, Luster AD, Scadden DT.

J Clin Invest. 2002 Apr;109(8):1101-10.

25.

Tissue source dictates lineage outcome of human fetal CD34(+)CD38(-) cells.

Poznansky MC, Olszak IT, Foxall RB, Piascik A, Adams GB, Evans RH, Cheng T, Scadden DT.

Exp Hematol. 2001 Jun;29(6):766-74.

PMID:
11378272
26.

Efficient generation of human T cells from a tissue-engineered thymic organoid.

Poznansky MC, Evans RH, Foxall RB, Olszak IT, Piascik AH, Hartman KE, Brander C, Meyer TH, Pykett MJ, Chabner KT, Kalams SA, Rosenzweig M, Scadden DT.

Nat Biotechnol. 2000 Jul;18(7):729-34.

PMID:
10888839
27.

Variable relationship between proviral DNA load and infectious virus titre in the peripheral blood mononuclear cells of HIV-1-infected individuals.

Bieniasz PD, Ariyoshi K, Bourelly MA, Bloor S, Foxall RB, Harwood EC, Weber JN.

AIDS. 1993 Jun;7(6):803-6.

PMID:
8103340

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