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CXCL4/Platelet Factor 4 is an agonist of CCR1 and drives human monocyte migration.

Fox JM, Kausar F, Day A, Osborne M, Hussain K, Mueller A, Lin J, Tsuchiya T, Kanegasaki S, Pease JE.

Sci Rep. 2018 Jun 21;8(1):9466. doi: 10.1038/s41598-018-27710-9.


Influencing the future of rural-focused pharmacy education: Identifying factors pertinent to pharmacy practice in rural health environments.

O'Connor SK, Fox JM, Joyner PU.

Curr Pharm Teach Learn. 2018 Apr;10(4):439-445. doi: 10.1016/j.cptl.2017.12.013. Epub 2018 Apr 2.


Mxra8 is a receptor for multiple arthritogenic alphaviruses.

Zhang R, Kim AS, Fox JM, Nair S, Basore K, Klimstra WB, Rimkunas R, Fong RH, Lin H, Poddar S, Crowe JE Jr, Doranz BJ, Fremont DH, Diamond MS.

Nature. 2018 May;557(7706):570-574. doi: 10.1038/s41586-018-0121-3. Epub 2018 May 16.


Quantifying urban growth patterns in Hanoi using landscape expansion modes and time series spatial metrics.

Nong DH, Lepczyk CA, Miura T, Fox JM.

PLoS One. 2018 May 7;13(5):e0196940. doi: 10.1371/journal.pone.0196940. eCollection 2018.


Photochemical syntheses, transformations, and bioorthogonal chemistry of trans-cycloheptene and sila trans-cycloheptene Ag(i) complexes.

Fang Y, Zhang H, Huang Z, Scinto SL, Yang JC, Am Ende CW, Dmitrenko O, Johnson DS, Fox JM.

Chem Sci. 2018 Jan 8;9(7):1953-1963. doi: 10.1039/c7sc04773h. eCollection 2018 Feb 21.


Fast, irreversible modification of cysteines through strain releasing conjugate additions of cyclopropenyl ketones.

Smith NJ, Rohlfing K, Sawicki LA, Kharkar PM, Boyd SJ, Kloxin AM, Fox JM.

Org Biomol Chem. 2018 Mar 28;16(12):2164-2169. doi: 10.1039/c8ob00166a. Epub 2018 Mar 9.


The Molecular Origin of Enthalpy/Entropy Compensation in Biomolecular Recognition.

Fox JM, Zhao M, Fink MJ, Kang K, Whitesides GM.

Annu Rev Biophys. 2018 May 20;47:223-250. doi: 10.1146/annurev-biophys-070816-033743. Epub 2018 Mar 5.


Glycans modify mesenchymal stem cell differentiation to impact on the function of resulting osteoblasts.

Wilson KM, Jagger AM, Walker M, Seinkmane E, Fox JM, Kröger R, Genever P, Ungar D.

J Cell Sci. 2018 Feb 14;131(4). pii: jcs209452. doi: 10.1242/jcs.209452.


Corrigendum to "Methodology for reliable and reproducible cryopreservation of human cervical tissue" [Cryobiology 77 (August) (2017) 14-18].

Fox JM, Wiggins RC, Moore JWJ, Brewer C, Hunter B, Andrew AC, Martin F.

Cryobiology. 2017 Dec;79:87. doi: 10.1016/j.cryobiol.2017.08.005. No abstract available.


Stereoselective Synthesis of Bicyclo[6.1.0]nonene Precursors of the Bioorthogonal Reagents s-TCO and BCN.

O'Brien JGK, Chintala SR, Fox JM.

J Org Chem. 2017 Dec 6. doi: 10.1021/acs.joc.7b02329. [Epub ahead of print]


Correction: Computationally guided discovery of a reactive, hydrophilic trans-5-oxocene dienophile for bioorthogonal labeling.

Lambert WD, Scinto SL, Dmitrenko O, Boyd SJ, Magboo R, Mehl RA, Chin JW, Fox JM, Wallace S.

Org Biomol Chem. 2017 Sep 13;15(35):7476. doi: 10.1039/c7ob90144e.


Computationally guided discovery of a reactive, hydrophilic trans-5-oxocene dienophile for bioorthogonal labeling.

Lambert WD, Scinto SL, Dmitrenko O, Boyd SJ, Magboo R, Mehl RA, Chin JW, Fox JM, Wallace S.

Org Biomol Chem. 2017 Aug 9;15(31):6640-6644. doi: 10.1039/c7ob01707c.



Hawman DW, Carpentier KS, Fox JM, May NA, Sanders W, Montgomery SA, Moorman NJ, Diamond MS, Morrison TE.

J Virol. 2017 Jul 26. pii: JVI.00816-17. doi: 10.1128/JVI.00816-17. [Epub ahead of print]


Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques.

Broeckel R, Fox JM, Haese N, Kreklywich CN, Sukulpovi-Petty S, Legasse A, Smith PP, Denton M, Corvey C, Krishnan S, Colgin LMA, Ducore RM, Lewis AD, Axthelm MK, Mandron M, Cortez P, Rothblatt J, Rao E, Focken I, Carter K, Sapparapau G, Crowe JE Jr, Diamond MS, Streblow DN.

PLoS Negl Trop Dis. 2017 Jun 19;11(6):e0005637. doi: 10.1371/journal.pntd.0005637. eCollection 2017 Jun.


Labor Analgesia Onset With Dural Puncture Epidural Versus Traditional Epidural Using a 26-Gauge Whitacre Needle and 0.125% Bupivacaine Bolus: A Randomized Clinical Trial.

Wilson SH, Wolf BJ, Bingham K, Scotland QS, Fox JM, Woltz EM, Hebbar L.

Anesth Analg. 2018 Feb;126(2):545-551. doi: 10.1213/ANE.0000000000002129.


Methodology for reliable and reproducible cryopreservation of human cervical tissue.

Fox JM, Wiggins RC, Moore JWJ, Brewer C, Andrew AC, Martin F.

Cryobiology. 2017 Aug;77:14-18. doi: 10.1016/j.cryobiol.2017.06.004. Epub 2017 Jun 9. Erratum in: Cryobiology. 2017 Dec;79:87.


Synthesis of Benzodihydrofurans by Asymmetric C-H Insertion Reactions of Donor/Donor Rhodium Carbenes.

Lamb KN, Squitieri RA, Chintala SR, Kwong AJ, Balmond EI, Soldi C, Dmitrenko O, Castiñeira Reis M, Chung R, Addison JB, Fettinger JC, Hein JE, Tantillo DJ, Fox JM, Shaw JT.

Chemistry. 2017 Sep 4;23(49):11843-11855. doi: 10.1002/chem.201701630. Epub 2017 Aug 10.


Predicting the infarct-related artery in STEMI from the surface ECG: independent validation of proposed criteria.

Eerdekens R, Chavez JF, Fox JM, Flaherty JD, Dekker LRC, Johnson NP.

EuroIntervention. 2017 Oct 20;13(8):953-961. doi: 10.4244/EIJ-D-17-00345.


Default mode functional connectivity is associated with social functioning in schizophrenia.

Fox JM, Abram SV, Reilly JL, Eack S, Goldman MB, Csernansky JG, Wang L, Smith MJ.

J Abnorm Psychol. 2017 May;126(4):392-405. doi: 10.1037/abn0000253. Epub 2017 Mar 30.


Modified mRNA Vaccines Protect against Zika Virus Infection.

Richner JM, Himansu S, Dowd KA, Butler SL, Salazar V, Fox JM, Julander JG, Tang WW, Shresta S, Pierson TC, Ciaramella G, Diamond MS.

Cell. 2017 Mar 23;169(1):176. doi: 10.1016/j.cell.2017.03.016. No abstract available.


Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase.

Fox JM, Kang K, Sastry M, Sherman W, Sankaran B, Zwart PH, Whitesides GM.

Angew Chem Int Ed Engl. 2017 Mar 27;56(14):3833-3837. doi: 10.1002/anie.201609409. Epub 2017 Mar 2.


Modified mRNA Vaccines Protect against Zika Virus Infection.

Richner JM, Himansu S, Dowd KA, Butler SL, Salazar V, Fox JM, Julander JG, Tang WW, Shresta S, Pierson TC, Ciaramella G, Diamond MS.

Cell. 2017 Mar 9;168(6):1114-1125.e10. doi: 10.1016/j.cell.2017.02.017. Epub 2017 Feb 17. Erratum in: Cell. 2017 Mar 23;169(1):176.


Perceived Risk of Avian Influenza and Urbanization in Northern Vietnam.

Finucane ML, Tuyen N, Saksena S, Spencer JH, Fox JM, Lam N, Thau TD, Vien TD, Lewis ND.

Ecohealth. 2017 Mar;14(1):144-154. doi: 10.1007/s10393-017-1213-5. Epub 2017 Feb 17.


Immune-Mediated Protection and Pathogenesis of Chikungunya Virus.

Fox JM, Diamond MS.

J Immunol. 2016 Dec 1;197(11):4210-4218. Review.


Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice.

Sapparapu G, Fernandez E, Kose N, Bin Cao, Fox JM, Bombardi RG, Zhao H, Nelson CA, Bryan AL, Barnes T, Davidson E, Mysorekar IU, Fremont DH, Doranz BJ, Diamond MS, Crowe JE.

Nature. 2016 Dec 15;540(7633):443-447. doi: 10.1038/nature20564. Epub 2016 Nov 7.


Fronto-temporal connectivity predicts cognitive empathy deficits and experiential negative symptoms in schizophrenia.

Abram SV, Wisner KM, Fox JM, Barch DM, Wang L, Csernansky JG, MacDonald AW 3rd, Smith MJ.

Hum Brain Mapp. 2017 Mar;38(3):1111-1124. doi: 10.1002/hbm.23439. Epub 2016 Oct 24.


Autocatalytic, bistable, oscillatory networks of biologically relevant organic reactions.

Semenov SN, Kraft LJ, Ainla A, Zhao M, Baghbanzadeh M, Campbell VE, Kang K, Fox JM, Whitesides GM.

Nature. 2016 Sep 29;537(7622):656-60. doi: 10.1038/nature19776.


Pathogenic Chikungunya Virus Evades B Cell Responses to Establish Persistence.

Hawman DW, Fox JM, Ashbrook AW, May NA, Schroeder KMS, Torres RM, Crowe JE Jr, Dermody TS, Diamond MS, Morrison TE.

Cell Rep. 2016 Aug 2;16(5):1326-1338. doi: 10.1016/j.celrep.2016.06.076. Epub 2016 Jul 21.


Acetylation of Surface Lysine Groups of a Protein Alters the Organization and Composition of Its Crystal Contacts.

Kang K, Choi JM, Fox JM, Snyder PW, Moustakas DT, Whitesides GM.

J Phys Chem B. 2016 Jul 14;120(27):6461-8. doi: 10.1021/acs.jpcb.6b01105. Epub 2016 Jun 24.


Rapid Bioorthogonal Chemistry Turn-on through Enzymatic or Long Wavelength Photocatalytic Activation of Tetrazine Ligation.

Zhang H, Trout WS, Liu S, Andrade GA, Hudson DA, Scinto SL, Dicker KT, Li Y, Lazouski N, Rosenthal J, Thorpe C, Jia X, Fox JM.

J Am Chem Soc. 2016 May 11;138(18):5978-83. doi: 10.1021/jacs.6b02168. Epub 2016 Apr 27.


A Mixed-Ligand Chiral Rhodium(II) Catalyst Enables the Enantioselective Total Synthesis of Piperarborenine B.

Panish RA, Chintala SR, Fox JM.

Angew Chem Int Ed Engl. 2016 Apr 11;55(16):4983-7. doi: 10.1002/anie.201600766. Epub 2016 Mar 16.


Long Terminal Repeat Circular DNA as Markers of Active Viral Replication of Human T Lymphotropic Virus-1 in Vivo.

Fox JM, Hilburn S, Demontis MA, Brighty DW, Rios Grassi MF, Galvão-Castro B, Taylor GP, Martin F.

Viruses. 2016 Mar 14;8(3):80. doi: 10.3390/v8030080.


Artemisinin-derived dimer ART-838 potently inhibited human acute leukemias, persisted in vivo, and synergized with antileukemic drugs.

Fox JM, Moynihan JR, Mott BT, Mazzone JR, Anders NM, Brown PA, Rudek MA, Liu JO, Arav-Boger R, Posner GH, Civin CI, Chen X.

Oncotarget. 2016 Feb 9;7(6):7268-79. doi: 10.18632/oncotarget.6896.


Rapid dissemination of human T-lymphotropic virus type 1 during primary infection in transplant recipients.

Cook LB, Melamed A, Demontis MA, Laydon DJ, Fox JM, Tosswill JH, de Freitas D, Price AD, Medcalf JF, Martin F, Neuberger JM, Bangham CR, Taylor GP.

Retrovirology. 2016 Jan 8;13:3. doi: 10.1186/s12977-015-0236-7.


Seroprevalence of HTLV-1 and HTLV-2 amongst mothers and children in Malawi within the context of a systematic review and meta-analysis of HTLV seroprevalence in Africa.

Fox JM, Mutalima N, Molyneux E, Carpenter LM, Taylor GP, Bland M, Newton R, Martin F.

Trop Med Int Health. 2016 Mar;21(3):312-24. doi: 10.1111/tmi.12659. Epub 2016 Feb 3. Review.


Rh-Catalyzed Intermolecular Reactions of α-Alkyl-α-Diazo Carbonyl Compounds with Selectivity over β-Hydride Migration.

DeAngelis A, Panish R, Fox JM.

Acc Chem Res. 2016 Jan 19;49(1):115-27. doi: 10.1021/acs.accounts.5b00425. Epub 2015 Dec 21.


Neutralizing Monoclonal Antibodies Block Chikungunya Virus Entry and Release by Targeting an Epitope Critical to Viral Pathogenesis.

Jin J, Liss NM, Chen DH, Liao M, Fox JM, Shimak RM, Fong RH, Chafets D, Bakkour S, Keating S, Fomin ME, Muench MO, Sherman MB, Doranz BJ, Diamond MS, Simmons G.

Cell Rep. 2015 Dec 22;13(11):2553-2564. doi: 10.1016/j.celrep.2015.11.043. Epub 2015 Dec 10.


Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.

Fox JM, Long F, Edeling MA, Lin H, van Duijl-Richter MKS, Fong RH, Kahle KM, Smit JM, Jin J, Simmons G, Doranz BJ, Crowe JE Jr, Fremont DH, Rossmann MG, Diamond MS.

Cell. 2015 Nov 19;163(5):1095-1107. doi: 10.1016/j.cell.2015.10.050. Epub 2015 Nov 6.


Systematic Evaluation of Bioorthogonal Reactions in Live Cells with Clickable HaloTag Ligands: Implications for Intracellular Imaging.

Murrey HE, Judkins JC, Am Ende CW, Ballard TE, Fang Y, Riccardi K, Di L, Guilmette ER, Schwartz JW, Fox JM, Johnson DS.

J Am Chem Soc. 2015 Sep 9;137(35):11461-75. doi: 10.1021/jacs.5b06847. Epub 2015 Aug 31.


Rh(II)-Catalyzed Reactions of Diazoesters with Organozinc Reagents.

Panish R, Selvaraj R, Fox JM.

Org Lett. 2015 Aug 21;17(16):3978-81. doi: 10.1021/acs.orglett.5b01836. Epub 2015 Aug 4.


Reply to Sullivan and Cruz: Defense of a simplified physical model.

Fox JM, Whitesides GM.

Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):E4165. doi: 10.1073/pnas.1511297112. Epub 2015 Jul 16. No abstract available.


Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus.

Smith SA, Silva LA, Fox JM, Flyak AI, Kose N, Sapparapu G, Khomandiak S, Ashbrook AW, Kahle KM, Fong RH, Swayne S, Doranz BJ, McGee CE, Heise MT, Pal P, Brien JD, Austin SK, Diamond MS, Dermody TS, Crowe JE Jr.

Cell Host Microbe. 2015 Jul 8;18(1):86-95. doi: 10.1016/j.chom.2015.06.009. Erratum in: Cell Host Microbe. 2015 Sep 9;18(3):382. Khomadiak, Solomiia [corrected to Khomandiak, Solomiia].


Conformationally Strained trans-Cyclooctene with Improved Stability and Excellent Reactivity in Tetrazine Ligation.

Darko A, Wallace S, Dmitrenko O, Machovina MM, Mehl RA, Chin JW, Fox JM.

Chem Sci. 2014 Oct 1;5(10):3770-3776.


CCR5 susceptibility to ligand-mediated down-modulation differs between human T lymphocytes and myeloid cells.

Fox JM, Kasprowicz R, Hartley O, Signoret N.

J Leukoc Biol. 2015 Jul;98(1):59-71. doi: 10.1189/jlb.2A0414-193RR. Epub 2015 May 8.


Investigating stereotypes of social anxiety.

Fox JM, Fernandez KC, Rodebaugh TL, Menatti AR, Weeks JW.

Anxiety Stress Coping. 2016;29(2):173-86. doi: 10.1080/10615806.2015.1035999. Epub 2015 May 11.


Meter-long multiblock copolymer microfibers via interfacial bioorthogonal polymerization.

Liu S, Zhang H, Remy RA, Deng F, Mackay ME, Fox JM, Jia X.

Adv Mater. 2015 May 6;27(17):2783-90. doi: 10.1002/adma.201500360. Epub 2015 Mar 30.


Interferon Lambda Upregulates IDO1 Expression in Respiratory Epithelial Cells After Influenza Virus Infection.

Fox JM, Crabtree JM, Sage LK, Tompkins SM, Tripp RA.

J Interferon Cytokine Res. 2015 Jul;35(7):554-62. doi: 10.1089/jir.2014.0052. Epub 2015 Mar 10.


Interactions between Hofmeister anions and the binding pocket of a protein.

Fox JM, Kang K, Sherman W, Héroux A, Sastry GM, Baghbanzadeh M, Lockett MR, Whitesides GM.

J Am Chem Soc. 2015 Mar 25;137(11):3859-66. doi: 10.1021/jacs.5b00187. Epub 2015 Mar 17.


Improved metabolic stability for 18F PET probes rapidly constructed via tetrazine trans-cyclooctene ligation.

Selvaraj R, Giglio B, Liu S, Wang H, Wang M, Yuan H, Chintala SR, Yap LP, Conti PS, Fox JM, Li Z.

Bioconjug Chem. 2015 Mar 18;26(3):435-42. doi: 10.1021/acs.bioconjchem.5b00089. Epub 2015 Mar 4.

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