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Structure-function guided modeling of chemokine-GPCR specificity for the chemokine XCL1 and its receptor XCR1.

Fox JC, Thomas MA, Dishman AF, Larsen O, Nakayama T, Yoshie O, Rosenkilde MM, Volkman BF.

Sci Signal. 2019 Sep 3;12(597). pii: eaat4128. doi: 10.1126/scisignal.aat4128.


Functional connectivity of emotional well-being: Overconnectivity between default and attentional networks is associated with attitudes of anger and aggression.

Weathersby FL, King JB, Fox JC, Loret A, Anderson JS.

Psychiatry Res Neuroimaging. 2019 Sep 30;291:52-62. doi: 10.1016/j.pscychresns.2019.08.001. Epub 2019 Aug 2.


A Prospective Evaluation of Point of Care Ultrasound Teaching in Switzerland.

Byrne C, Kahl N, Knight B, Lee M, Morley S, Lahham S, Bingisser R, Thompson M, Shniter I, Valdes V, Fox JC.

J Med Ultrasound. 2019 Apr-Jun;27(2):92-96. doi: 10.4103/JMU.JMU_57_18. Epub 2019 Feb 26.


Generalizability and reproducibility of functional connectivity in autism.

King JB, Prigge MBD, King CK, Morgan J, Weathersby F, Fox JC, Dean DC 3rd, Freeman A, Villaruz JAM, Kane KL, Bigler ED, Alexander AL, Lange N, Zielinski B, Lainhart JE, Anderson JS.

Mol Autism. 2019 Jun 24;10:27. doi: 10.1186/s13229-019-0273-5. eCollection 2019.


First-in-Human Study of AG10, a Novel, Oral, Specific, Selective, and Potent Transthyretin Stabilizer for the Treatment of Transthyretin Amyloidosis: A Phase 1 Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Adult Volunteers.

Fox JC, Hellawell JL, Rao S, O'Reilly T, Lumpkin R, Jernelius J, Gretler D, Sinha U.

Clin Pharmacol Drug Dev. 2019 Jun 6. doi: 10.1002/cpdd.700. [Epub ahead of print]


A comparison of simulation versus didactics for teaching ultrasound to Swiss medical students.

Shah S, Tohmasi S, Frisch E, Anderson A, Almog R, Lahham S, Bingisser R, Fox JC.

World J Emerg Med. 2019;10(3):169-176. doi: 10.5847/wjem.j.1920-8642.2019.03.007.


Resistance mechanisms and cross-resistance for a pyridine-pyrimidine amide inhibitor of microtubule polymerization.

Fox JC, Evans AT, Blomfield MP, Livingstone SK, Tenney SR, Webster JB, Perry K, Hill JT, Bikman BT, Hansen MDH.

Bioorg Med Chem Lett. 2019 Jul 1;29(13):1647-1653. doi: 10.1016/j.bmcl.2019.04.035. Epub 2019 Apr 25.


Point-of-Care Ultrasonography in the Diagnosis of Retinal Detachment, Vitreous Hemorrhage, and Vitreous Detachment in the Emergency Department.

Lahham S, Shniter I, Thompson M, Le D, Chadha T, Mailhot T, Kang TL, Chiem A, Tseeng S, Fox JC.

JAMA Netw Open. 2019 Apr 5;2(4):e192162. doi: 10.1001/jamanetworkopen.2019.2162.


Transthyretin Stabilization by AG10 in Symptomatic Transthyretin Amyloid Cardiomyopathy.

Judge DP, Heitner SB, Falk RH, Maurer MS, Shah SJ, Witteles RM, Grogan M, Selby VN, Jacoby D, Hanna M, Nativi-Nicolau J, Patel J, Rao S, Sinha U, Turtle CW, Fox JC.

J Am Coll Cardiol. 2019 Jul 23;74(3):285-295. doi: 10.1016/j.jacc.2019.03.012. Epub 2019 Mar 15.


A Prospective, Multicenter Evaluation of Point-of-care Ultrasound for Small-bowel Obstruction in the Emergency Department.

Becker BA, Lahham S, Gonzales MA, Nomura JT, Bui MK, Truong TA, Stahlman BA, Fox JC, Kehrl T.

Acad Emerg Med. 2019 Aug;26(8):921-930. doi: 10.1111/acem.13713. Epub 2019 Mar 12.


Can an 8th grade student learn point of care ultrasound?

Kwon AS, Lahham S, Fox JC.

World J Emerg Med. 2019;10(2):109-113. doi: 10.5847/wjem.j.1920-8642.2019.02.007.


Assessment of clinical dehydration using point of care ultrasound for pediatric patients in rural Panama.

Mazza G, Romo CM, Torres M, Duffens A, Vyas A, Moran K, Livingston J, Gonzales S, Lahham S, Shniter I, Thompson M, Fox JC.

World J Emerg Med. 2019;10(1):46-50. doi: 10.5847/wjem.j.1920-8642.2019.01.007.


Genotype and Lifetime Burden of Disease in Hypertrophic Cardiomyopathy: Insights from the Sarcomeric Human Cardiomyopathy Registry (SHaRe).

Ho CY, Day SM, Ashley EA, Michels M, Pereira AC, Jacoby D, Cirino AL, Fox JC, Lakdawala NK, Ware JS, Caleshu CA, Helms AS, Colan SD, Girolami F, Cecchi F, Seidman CE, Sajeev G, Signorovitch J, Green EM, Olivotto I.

Circulation. 2018 Oct 2;138(14):1387-1398. doi: 10.1161/CIRCULATIONAHA.117.033200. Epub 2018 Aug 23.


Tricuspid annular plane of systolic excursion to prognosticate acute pulmonary symptomatic embolism (TAPSEPAPSE study).

Lahham S, Fox JC, Thompson M, Nakornchai T, Alruwaili B, Doman G, May Lee S, Shafi A, Shniter I, Valdes V, Zhang L.

J Ultrasound Med. 2019 Mar;38(3):695-702. doi: 10.1002/jum.14753. Epub 2018 Sep 4.


Comparing Point-of-care-ultrasound (POCUS) to MRI for the Diagnosis of Medial Compartment Knee Injuries.

Ghosh N, Kruse D, Subeh M, Lahham S, Fox JC.

J Med Ultrasound. 2017 Jul-Sep;25(3):167-172. doi: 10.1016/j.jmu.2017.06.004. Epub 2017 Aug 17.


Feasibility study of minimally trained medical students using the Rural Obstetrical Ultrasound Triage Exam (ROUTE) in rural Panama.

Vyas A, Moran K, Livingston J, Gonzales S, Torres M, Duffens A, Romo CM, Mazza G, Livingston B, Lahham S, Fox JC.

World J Emerg Med. 2018;9(3):216-222. doi: 10.5847/wjem.j.1920-8642.2018.03.009.


Documenting the Growth of Ultrasound Research in Emergency Medicine Through a Bibliometric Analysis of Accepted Academic Conference Abstracts.

Prats MI, Bahner DP, Panchal AR, King AM, Way DP, Lin S, Fox JC, Boulger CT.

J Ultrasound Med. 2018 Dec;37(12):2777-2784. doi: 10.1002/jum.14634. Epub 2018 Apr 15.


Ultrasound curriculum taught by first-year medical students: A four-year experience in Tanzania.

Denny SP, Minteer WB, Fenning RTH, Aggarwal S, Lee DH, Raja SK, Raman KR, Farfel AO, Patel PA, MarkLieber, Bernstein ME, Lahham S, Fox JC.

World J Emerg Med. 2018;9(1):33-40. doi: 10.5847/wjem.j.1920-8642.2018.01.005.


Stu2 uses a 15-nm parallel coiled coil for kinetochore localization and concomitant regulation of the mitotic spindle.

Haase KP, Fox JC, Byrnes AE, Adikes RC, Speed SK, Haase J, Friedman B, Cook DM, Bloom K, Rusan NM, Slep KC.

Mol Biol Cell. 2018 Feb 1;29(3):285-294. doi: 10.1091/mbc.E17-01-0057. Epub 2017 Nov 29.


Utility of common bile duct measurement in ED point of care ultrasound: A prospective study.

Lahham S, Becker BA, Gari A, Bunch S, Alvarado M, Anderson CL, Viquez E, Spann SC, Fox JC.

Am J Emerg Med. 2018 Jun;36(6):962-966. doi: 10.1016/j.ajem.2017.10.064. Epub 2017 Nov 20.


Procedural simulation: medical student preference and value of three task trainers for ultrasound guided regional anesthesia.

Lahham S, Smith T, Baker J, Purdy A, Frumin E, Winners B, Wilson SP, Gari A, Fox JC.

World J Emerg Med. 2017;8(4):287-291. doi: 10.5847/wjem.j.1920-8642.2017.04.007.


Evaluation of a point of care ultrasound curriculum for Indonesian physicians taught by first-year medical students.

Lee JB, Tse C, Keown T, Louthan M, Gabriel C, Anshus A, Hasjim B, Lee K, Kim E, Yu L, Yu A, Lahham S, Bunch S, Alvarado M, Gari A, Fox JC.

World J Emerg Med. 2017;8(4):281-286. doi: 10.5847/wjem.j.1920-8642.2017.04.006.



Fox JC, Lahham S, Maldonado G, Klaus S, Aish B, Sylwanowicz LV, Yanuck J, Wilson SP, Shieh M, Anderson CL, English C, Mayer R, Mohan UR.

J Ultrasound Med. 2018 Jun;37(6):1576. doi: 10.1002/jum.14441. Epub 2017 Oct 9. No abstract available.


Navigating the Future of Cardiovascular Drug Development-Leveraging Novel Approaches to Drive Innovation and Drug Discovery: Summary of Findings from the Novel Cardiovascular Therapeutics Conference.

Povsic TJ, Scott R, Mahaffey KW, Blaustein R, Edelberg JM, Lefkowitz MP, Solomon SD, Fox JC, Healy KE, Khakoo AY, Losordo DW, Malik FI, Monia BP, Montgomery RL, Riesmeyer J, Schwartz GG, Zelenkofske SL, Wu JC, Wasserman SM, Roe MT.

Cardiovasc Drugs Ther. 2017 Aug;31(4):445-458. doi: 10.1007/s10557-017-6739-9. Review.


Comparison of ultrasound-measured properties of the common carotid artery to tobacco smoke exposure in a cohort of Indonesian patients.

Yu AR, Hasjim B, Yu LE, Gabriel C, Anshus A, Lee JB, Louthan MJ, Kim EC, Lee K, Tse C, Keown T, Lahham S, Alvarado M, Bunch S, Gari A, Fox JC.

World J Emerg Med. 2017;8(3):177-183. doi: 10.5847/wjem.j.1920-8642.2017.03.003.


A Prospective Evaluation of Transverse Tracheal Sonography During Emergent Intubation by Emergency Medicine Resident Physicians.

Lahham S, Baydoun J, Bailey J, Sandoval S, Wilson SP, Fox JC, Slattery DE.

J Ultrasound Med. 2017 Oct;36(10):2079-2085. doi: 10.1002/jum.14231. Epub 2017 May 15.


Accurate detection of low prevalence AKT1 E17K mutation in tissue or plasma from advanced cancer patients.

de Bruin EC, Whiteley JL, Corcoran C, Kirk PM, Fox JC, Armisen J, Lindemann JPO, Schiavon G, Ambrose HJ, Kohlmann A.

PLoS One. 2017 May 4;12(5):e0175779. doi: 10.1371/journal.pone.0175779. eCollection 2017.


Hypertrophic Cardiomyopathy in Youth Athletes: Successful Screening With Point-of-Care Ultrasound by Medical Students.

Fox JC, Lahham S, Maldonado G, Klaus S, Aish B, Sylwanowicz LV, Yanuck J, Wilson SP, Shieh M, Anderson CL, English C, Mayer R, Mohan UR.

J Ultrasound Med. 2017 Jun;36(6):1109-1115. doi: 10.7863/ultra.16.06044. Epub 2017 Mar 4.


Simplified point-of-care ultrasound protocol to confirm central venous catheter placement: A prospective study.

Wilson SP, Assaf S, Lahham S, Subeh M, Chiem A, Anderson C, Shwe S, Nguyen R, Fox JC.

World J Emerg Med. 2017;8(1):25-28. doi: 10.5847/wjem.j.1920-8642.2017.01.004.


Implementation of a 4-Year Point-of-Care Ultrasound Curriculum in a Liaison Committee on Medical Education-Accredited US Medical School.

Wilson SP, Mefford JM, Lahham S, Lotfipour S, Subeh M, Maldonado G, Spann S, Fox JC.

J Ultrasound Med. 2017 Feb;36(2):321-325. doi: 10.7863/ultra.16.03068. Epub 2016 Dec 10. Erratum in: J Ultrasound Med. 2017 Jun;36(6):1289.


Paving the way to a bioresorbable technology: Development of the absorb BRS program.

Perkins LE, Kossuth MB, Fox JC, Rapoza RJ.

Catheter Cardiovasc Interv. 2016 Nov;88(S1):1-9. doi: 10.1002/ccd.26811. Review.


Ranking Practice Variability in the Medical Student Performance Evaluation: So Bad, It's "Good".

Boysen Osborn M, Mattson J, Yanuck J, Anderson C, Tekian A, Fox JC, Harris IB.

Acad Med. 2016 Nov;91(11):1540-1545.


Point-of-care ultrasound versus radiology department pelvic ultrasound on emergency department length of stay.

Wilson SP, Connolly K, Lahham S, Subeh M, Fischetti C, Chiem A, Aspen A, Anderson C, Fox JC.

World J Emerg Med. 2016;7(3):178-82. doi: 10.5847/wjem.j.1920-8642.2016.03.003.


Prospective evaluation of point-of-care ultrasound for pre-procedure identification of landmarks versus traditional palpation for lumbar puncture.

Lahham S, Schmalbach P, Wilson SP, Ludeman L, Subeh M, Chao J, Albadawi N, Mohammadi N, Fox JC.

World J Emerg Med. 2016;7(3):173-7. doi: 10.5847/wjem.j.1920-8642.2016.03.002.


Thrombosis of Inferior Vena Cava Diagnosed Using Point-of-Care Ultrasound After Pediatric Near-Syncope.

Lahham S, Tsai L, Wilson SP, Assaf S, Navarro R, Banimahd F, Subeh M, Barton ED, Barbera A, Fox JC.

J Emerg Med. 2016 Oct;51(4):e89-e91. doi: 10.1016/j.jemermed.2016.06.008. Epub 2016 Aug 18.


Pilot Study to Determine Accuracy of Posterior Approach Ultrasound for Shoulder Dislocation by Novice Sonographers.

Lahham S, Becker B, Chiem A, Joseph LM, Anderson CL, Wilson SP, Subeh M, Trinh A, Viquez E, Fox JC.

West J Emerg Med. 2016 May;17(3):377-82. doi: 10.5811/westjem.2016.2.29290. Epub 2016 Apr 26.


Ultrasound-guided central venous access: which probe is preferred for viewing the subclavian vein using a supraclavicular approach?

Lahham S, Wilson SP, Subeh M, Butterfield M, Albakri AR, Bashir R, Fox JC.

Am J Emerg Med. 2016 Sep;34(9):1761-4. doi: 10.1016/j.ajem.2016.06.013. Epub 2016 Jun 7.


Pre-hospital assessment with ultrasound in emergencies: implementation in the field.

Rooney KP, Lahham S, Lahham S, Anderson CL, Bledsoe B, Sloane B, Joseph L, Osborn MB, Fox JC.

World J Emerg Med. 2016;7(2):117-23. doi: 10.5847/wjem.j.1920-8642.2016.02.006.


The total synthesis of K-252c (staurosporinone) via a sequential C-H functionalisation strategy.

Fox JC, Gilligan RE, Pitts AK, Bennett HR, Gaunt MJ.

Chem Sci. 2016 Apr 21;7(4):2706-2710. doi: 10.1039/c5sc04399a. Epub 2016 Jan 21.


Randomized study of effectiveness of computerized ultrasound simulators for an introductory course for residents in Brazil.

Silva JP, Plescia T, Molina N, Tonelli AC, Langdorf M, Fox JC.

J Educ Eval Health Prof. 2016 Apr 4;13:16. doi: 10.3352/jeehp.2016.13.16. eCollection 2016.


Ultrasound-Guided Cannulation: Time to Bring Subclavian Central Lines Back.

Rezayat T, Stowell JR, Kendall JL, Turner E, Fox JC, Barjaktarevic I.

West J Emerg Med. 2016 Mar;17(2):216-21. doi: 10.5811/westjem.2016.1.29462. Epub 2016 Mar 2. Review.


Retrospective Review of Ocular Point-of-Care Ultrasound for Detection of Retinal Detachment.

Jacobsen B, Lahham S, Lahham S, Patel A, Spann S, Fox JC.

West J Emerg Med. 2016 Mar;17(2):196-200. doi: 10.5811/westjem.2015.12.28711. Epub 2016 Mar 2.


Examination of Glycosaminoglycan Binding Sites on the XCL1 Dimer.

Fox JC, Tyler RC, Peterson FC, Dyer DP, Zhang F, Linhardt RJ, Handel TM, Volkman BF.

Biochemistry. 2016 Mar 1;55(8):1214-25. doi: 10.1021/acs.biochem.5b01329. Epub 2016 Feb 17.


Integration of Ultrasound in Medical Education at United States Medical Schools: A National Survey of Directors' Experiences.

Dinh VA, Fu JY, Lu S, Chiem A, Fox JC, Blaivas M.

J Ultrasound Med. 2016 Feb;35(2):413-9. doi: 10.7863/ultra.15.05073. Epub 2016 Jan 18.


Integration of Ultrasound in Undergraduate Medical Education at the California Medical Schools: A Discussion of Common Challenges and Strategies From the UMeCali Experience.

Chiem AT, Soucy Z, Dinh VA, Chilstrom M, Gharahbaghian L, Shah V, Medak A, Nagdev A, Jang T, Stark E, Hussain A, Lobo V, Pera A, Fox JC.

J Ultrasound Med. 2016 Feb;35(2):221-33. doi: 10.7863/ultra.15.05006. Epub 2016 Jan 13.


A feasibility study to determine if minimally trained medical students can identify markers of chronic parasitic infection using bedside ultrasound in rural Tanzania.

Barsky M, Kushner L, Ansbro M, Bowman K, Sassounian M, Gustafson K, Lahham S, Joseph L, Fox JC.

World J Emerg Med. 2015;6(4):293-8. doi: 10.5847/wjem.j.1920-8642.2015.04.008.


Feasibility study of first-year medical students identifying cardiac anatomy using ultrasound in rural Panama.

Miner B, Purdy A, Curtis L, Simonson K, Shumway C, Baker J, Vaughan J, Percival K, Sanchez O, Lahham S, Joseph L, Fox JC.

World J Emerg Med. 2015;6(3):191-5. doi: 10.5847/wjem.j.1920-8642.2015.03.005.


Engineering Metamorphic Chemokine Lymphotactin/XCL1 into the GAG-Binding, HIV-Inhibitory Dimer Conformation.

Fox JC, Tyler RC, Guzzo C, Tuinstra RL, Peterson FC, Lusso P, Volkman BF.

ACS Chem Biol. 2015 Nov 20;10(11):2580-8. doi: 10.1021/acschembio.5b00542. Epub 2015 Sep 2.


SHaRe: advancing the goal of effective treatment for cardiomyopathy.

Fox JC.

Eur Heart J. 2015 May 14;36(19):1142-3.


The Absence of Gallstones on Point-of-Care Ultrasound Rules Out Acute Cholecystitis.

Villar J, Summers SM, Menchine MD, Fox JC, Wang R.

J Emerg Med. 2015 Oct;49(4):475-80. doi: 10.1016/j.jemermed.2015.04.037. Epub 2015 Jul 7.

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