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Items: 1 to 50 of 282

1.

Macrophages are the primary effector cells in IL-7-induced arthritis.

Kim SJ, Chang HJ, Volin MV, Umar S, Van Raemdonck K, Chevalier A, Palasiewicz K, Christman JW, Volkov S, Arami S, Maz M, Mehta A, Zomorrodi RK, Fox DA, Sweiss N, Shahrara S.

Cell Mol Immunol. 2019 Jun 13. doi: 10.1038/s41423-019-0235-z. [Epub ahead of print]

PMID:
31197255
2.

Absence of complement component 3 does not prevent classical pathway-mediated hemolysis.

Zhang L, Dai Y, Huang P, Saunders TL, Fox DA, Xu J, Lin F.

Blood Adv. 2019 Jun 25;3(12):1808-1814. doi: 10.1182/bloodadvances.2019031591.

3.

Angiogenic and Arthritogenic Properties of the Soluble Form of CD13.

Du Y, Lu C, Morgan RL, Stinson WA, Campbell PL, Cealey E, Fu W, Lepore NJ, Hervoso JL, Cui H, Urquhart AG, Lawton JN, Chung KC, Fox DA, Amin MA.

J Immunol. 2019 Jul 15;203(2):360-369. doi: 10.4049/jimmunol.1801276. Epub 2019 Jun 12.

PMID:
31189572
4.

Non-invasive assessment of aortic stiffness and blood pressure in young Turner syndrome patients.

Fox DA, Kang KT, Potts JE, Bradley TJ, Stewart LL, Dionne JM, Sandor GGS.

J Pediatr Endocrinol Metab. 2019 May 27;32(5):489-498. doi: 10.1515/jpem-2018-0346.

PMID:
31042642
5.

5-Aryl-1,3,4-oxadiazol-2-ylthioalkanoic Acids: A Highly Potent New Class of Inhibitors of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Response Factor (SRF)-Mediated Gene Transcription as Potential Antifibrotic Agents for Scleroderma.

Kahl DJ, Hutchings KM, Lisabeth EM, Haak AJ, Leipprandt JR, Dexheimer T, Khanna D, Tsou PS, Campbell PL, Fox DA, Wen B, Sun D, Bailie M, Neubig RR, Larsen SD.

J Med Chem. 2019 May 9;62(9):4350-4369. doi: 10.1021/acs.jmedchem.8b01772. Epub 2019 Apr 18.

6.

Citrullinated Inhibitor of DNA Binding 1 Is a Novel Autoantigen in Rheumatoid Arthritis.

Ohara RA, Edhayan G, Rasmussen SM, Isozaki T, Remmer HA, Lanigan TM, Campbell PL, Urquhart AG, Lawton JN, Chung KC, Fox DA, Ruth JH.

Arthritis Rheumatol. 2019 Mar 12. doi: 10.1002/art.40886. [Epub ahead of print]

PMID:
30861322
7.

Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma.

Tsou PS, Campbell P, Amin MA, Coit P, Miller S, Fox DA, Khanna D, Sawalha AH.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3695-3702. doi: 10.1073/pnas.1813006116. Epub 2019 Feb 12.

8.

Novel Therapeutic Strategy for Pharyngoesophageal Stricture following Total Laryngectomy.

Wu PI, Szczesniak MM, Fox DA, Maclean J, Blom ED, Cook IJ.

Otolaryngol Head Neck Surg. 2019 Mar;160(3):567-569. doi: 10.1177/0194599818815164. Epub 2018 Dec 11.

PMID:
30526296
9.

Type 1 diabetes outcomes: Does distance to clinic matter?

Fox DA, Islam N, Amed S.

Pediatr Diabetes. 2018 Nov;19(7):1331-1336. doi: 10.1111/pedi.12749. Epub 2018 Sep 3.

PMID:
30101515
10.

Role of Complement in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy.

Xu J, Zhang L, Xie M, Li Y, Huang P, Saunders TL, Fox DA, Rosenquist R, Lin F.

J Immunol. 2018 Jun 15;200(12):4094-4101. doi: 10.4049/jimmunol.1701716. Epub 2018 Apr 25.

11.

Response to comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis".

Carmona-Rivera C, Bicker KL, Thompson PR, Buckner JH, Robinson WH, Fox DA, Kaplan MJ.

Sci Immunol. 2018 Mar 30;3(21). pii: eaar3701. doi: 10.1126/sciimmunol.aar3701.

12.

The role of CD6 in autoimmune diseases.

Fox DA.

Cell Mol Immunol. 2018 Nov;15(11):1001-1002. doi: 10.1038/s41423-018-0015-1. Epub 2018 Mar 23. No abstract available.

PMID:
29572546
13.

Clinical and experimental evidence for targeting CD6 in immune-based disorders.

Consuegra-Fernández M, Lin F, Fox DA, Lozano F.

Autoimmun Rev. 2018 May;17(5):493-503. doi: 10.1016/j.autrev.2017.12.004. Epub 2018 Mar 9. Review.

PMID:
29526637
14.

Targeting CD6 for the treatment of experimental autoimmune uveitis.

Zhang L, Li Y, Qiu W, Bell BA, Dvorina N, Baldwin WM 3rd, Singer N, Kern T, Caspi RR, Fox DA, Lin F.

J Autoimmun. 2018 Jun;90:84-93. doi: 10.1016/j.jaut.2018.02.004. Epub 2018 Feb 19.

15.

Transcriptional Profiling of Synovial Macrophages Using Minimally Invasive Ultrasound-Guided Synovial Biopsies in Rheumatoid Arthritis.

Mandelin AM 2nd, Homan PJ, Shaffer AM, Cuda CM, Dominguez ST, Bacalao E, Carns M, Hinchcliff M, Lee J, Aren K, Thakrar A, Montgomery AB, Bridges SL Jr, Bathon JM, Atkinson JP, Fox DA, Matteson EL, Buckley CD, Pitzalis C, Parks D, Hughes LB, Geraldino-Pardilla L, Ike R, Phillips K, Wright K, Filer A, Kelly S, Ruderman EM, Morgan V, Abdala-Valencia H, Misharin AV, Budinger GS, Bartom ET, Pope RM, Perlman H, Winter DR.

Arthritis Rheumatol. 2018 Jun;70(6):841-854. doi: 10.1002/art.40453. Epub 2018 May 3.

16.

A unique role for galectin-9 in angiogenesis and inflammatory arthritis.

O'Brien MJ, Shu Q, Stinson WA, Tsou PS, Ruth JH, Isozaki T, Campbell PL, Ohara RA, Koch AE, Fox DA, Amin MA.

Arthritis Res Ther. 2018 Feb 12;20(1):31. doi: 10.1186/s13075-018-1519-x.

17.

IL-11 facilitates a novel connection between RA joint fibroblasts and endothelial cells.

Elshabrawy HA, Volin MV, Essani AB, Chen Z, McInnes IB, Van Raemdonck K, Palasiewicz K, Arami S, Gonzalez M, Ashour HM, Kim SJ, Zhou G, Fox DA, Shahrara S.

Angiogenesis. 2018 May;21(2):215-228. doi: 10.1007/s10456-017-9589-y. Epub 2018 Jan 11.

18.

Nonalcoholic fatty liver disease in spinal and bulbar muscular atrophy.

Guber RD, Takyar V, Kokkinis A, Fox DA, Alao H, Kats I, Bakar D, Remaley AT, Hewitt SM, Kleiner DE, Liu CY, Hadigan C, Fischbeck KH, Rotman Y, Grunseich C.

Neurology. 2017 Dec 12;89(24):2481-2490. doi: 10.1212/WNL.0000000000004748. Epub 2017 Nov 15.

19.

Establishing clinical severity for PROMIS® measures in adult patients with rheumatic diseases.

Nagaraja V, Mara C, Khanna PP, Namas R, Young A, Fox DA, Laing T, McCune WJ, Dodge C, Rizzo D, Almackenzie M, Khanna D.

Qual Life Res. 2018 Mar;27(3):755-764. doi: 10.1007/s11136-017-1709-z. Epub 2017 Oct 5.

20.

Type 1 diabetes incidence and prevalence trends in a cohort of Canadian children and youth.

Fox DA, Islam N, Sutherland J, Reimer K, Amed S.

Pediatr Diabetes. 2018 May;19(3):501-505. doi: 10.1111/pedi.12566. Epub 2017 Aug 31.

PMID:
28857360
21.

Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease.

Totzke J, Gurbani D, Raphemot R, Hughes PF, Bodoor K, Carlson DA, Loiselle DR, Bera AK, Eibschutz LS, Perkins MM, Eubanks AL, Campbell PL, Fox DA, Westover KD, Haystead TAJ, Derbyshire ER.

Cell Chem Biol. 2017 Aug 17;24(8):1029-1039.e7. doi: 10.1016/j.chembiol.2017.07.011.

22.

CD318 is a ligand for CD6.

Enyindah-Asonye G, Li Y, Ruth JH, Spassov DS, Hebron KE, Zijlstra A, Moasser MM, Wang B, Singer NG, Cui H, Ohara RA, Rasmussen SM, Fox DA, Lin F.

Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):E6912-E6921. doi: 10.1073/pnas.1704008114. Epub 2017 Jul 31.

23.

Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis.

Carmona-Rivera C, Carlucci PM, Moore E, Lingampalli N, Uchtenhagen H, James E, Liu Y, Bicker KL, Wahamaa H, Hoffmann V, Catrina AI, Thompson P, Buckner JH, Robinson WH, Fox DA, Kaplan MJ.

Sci Immunol. 2017 Apr;2(10). pii: eaag3358. doi: 10.1126/sciimmunol.aag3358. Epub 2017 Apr 14.

24.

Synovial cellular and molecular markers in rheumatoid arthritis.

Asif Amin M, Fox DA, Ruth JH.

Semin Immunopathol. 2017 Jun;39(4):385-393. doi: 10.1007/s00281-017-0631-3. Epub 2017 May 11. Review.

25.

Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma.

Hutchings KM, Lisabeth EM, Rajeswaran W, Wilson MW, Sorenson RJ, Campbell PL, Ruth JH, Amin A, Tsou PS, Leipprandt JR, Olson SR, Wen B, Zhao T, Sun D, Khanna D, Fox DA, Neubig RR, Larsen SD.

Bioorg Med Chem Lett. 2017 Apr 15;27(8):1744-1749. doi: 10.1016/j.bmcl.2017.02.070. Epub 2017 Mar 10.

26.

CD6 as a potential target for treating multiple sclerosis.

Li Y, Singer NG, Whitbred J, Bowen MA, Fox DA, Lin F.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2687-2692. doi: 10.1073/pnas.1615253114. Epub 2017 Feb 16.

27.

DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis.

Mor-Vaknin N, Saha A, Legendre M, Carmona-Rivera C, Amin MA, Rabquer BJ, Gonzales-Hernandez MJ, Jorns J, Mohan S, Yalavarthi S, Pai DA, Angevine K, Almburg SJ, Knight JS, Adams BS, Koch AE, Fox DA, Engelke DR, Kaplan MJ, Markovitz DM.

Nat Commun. 2017 Feb 6;8:14252. doi: 10.1038/ncomms14252.

28.

Increased proliferation of late-born retinal progenitor cells by gestational lead exposure delays rod and bipolar cell differentiation.

Chaney SY, Mukherjee S, Giddabasappa A, Rueda EM, Hamilton WR, Johnson JE Jr, Fox DA.

Mol Vis. 2016 Dec 24;22:1468-1489. eCollection 2016.

29.

TLRs, future potential therapeutic targets for RA.

Elshabrawy HA, Essani AE, Szekanecz Z, Fox DA, Shahrara S.

Autoimmun Rev. 2017 Feb;16(2):103-113. doi: 10.1016/j.autrev.2016.12.003. Epub 2016 Dec 15. Review.

30.

Adult lead exposure increases blood-retinal permeability: A risk factor for retinal vascular disease.

Shen XF, Huang P, Fox DA, Lin Y, Zhao ZH, Wang W, Wang JY, Liu XQ, Chen JY, Luo WJ.

Neurotoxicology. 2016 Dec;57:145-152. doi: 10.1016/j.neuro.2016.09.013. Epub 2016 Sep 20.

PMID:
27663850
31.

Seven-Year Outcomes of the Silicone Arthroplasty in Rheumatoid Arthritis Prospective Cohort Study.

Chung KC, Kotsis SV, Burns PB, Burke FD, Wilgis EFS, Fox DA, Kim HM.

Arthritis Care Res (Hoboken). 2017 Jul;69(7):973-981. doi: 10.1002/acr.23105. Epub 2017 Jun 9.

32.

Social Network Analysis Reveals Potential Fission-Fusion Behavior in a Shark.

Haulsee DE, Fox DA, Breece MW, Brown LM, Kneebone J, Skomal GB, Oliver MJ.

Sci Rep. 2016 Sep 30;6:34087. doi: 10.1038/srep34087.

33.

Localization, Shedding, Regulation and Function of Aminopeptidase N/CD13 on Fibroblast like Synoviocytes.

Morgan RL, Behbahani-Nejad N, Endres J, Amin MA, Lepore NJ, Du Y, Urquhart A, Chung KC, Fox DA.

PLoS One. 2016 Sep 22;11(9):e0162008. doi: 10.1371/journal.pone.0162008. eCollection 2016.

34.

Transforming growth factor β activated kinase 1: a potential therapeutic target for rheumatic diseases.

Fechtner S, Fox DA, Ahmed S.

Rheumatology (Oxford). 2017 Jul 1;56(7):1060-1068. doi: 10.1093/rheumatology/kew301. Review.

35.

The cellular and compartmental profile of mouse retinal glycolysis, tricarboxylic acid cycle, oxidative phosphorylation, and ~P transferring kinases.

Rueda EM, Johnson JE Jr, Giddabasappa A, Swaroop A, Brooks MJ, Sigel I, Chaney SY, Fox DA.

Mol Vis. 2016 Jul 23;22:847-85. eCollection 2016.

36.

Histone Deacetylase 5 Is Overexpressed in Scleroderma Endothelial Cells and Impairs Angiogenesis via Repression of Proangiogenic Factors.

Tsou PS, Wren JD, Amin MA, Schiopu E, Fox DA, Khanna D, Sawalha AH.

Arthritis Rheumatol. 2016 Dec;68(12):2975-2985. doi: 10.1002/art.39828.

37.

Phospholipase D enzymes facilitate IL-17- and TNFα-induced expression of proinflammatory genes in rheumatoid arthritis synovial fibroblasts (RASF).

Friday SC, Fox DA.

Immunol Lett. 2016 Jun;174:9-18. doi: 10.1016/j.imlet.2016.04.001. Epub 2016 Apr 4.

PMID:
27058440
38.

RONIN Is an Essential Transcriptional Regulator of Genes Required for Mitochondrial Function in the Developing Retina.

Poché RA, Zhang M, Rueda EM, Tong X, McElwee ML, Wong L, Hsu CW, Dejosez M, Burns AR, Fox DA, Martin JF, Zwaka TP, Dickinson ME.

Cell Rep. 2016 Feb 23;14(7):1684-1697. doi: 10.1016/j.celrep.2016.01.039. Epub 2016 Feb 11.

39.

Implantation and Recovery of Long-Term Archival Transceivers in a Migratory Shark with High Site Fidelity.

Haulsee DE, Fox DA, Breece MW, Clauss TM, Oliver MJ.

PLoS One. 2016 Feb 5;11(2):e0148617. doi: 10.1371/journal.pone.0148617. eCollection 2016.

40.

The History, Status, Gaps, and Future Directions of Neurotoxicology in China.

Cai T, Luo W, Ruan D, Wu YJ, Fox DA, Chen J.

Environ Health Perspect. 2016 Jun;124(6):722-32. doi: 10.1289/ehp.1409566. Epub 2016 Jan 29. Review.

41.

Photoreceptor Mitochondrial Reserve Capacity: Is It the Etiology for Differential Compartmental Vulnerability?

Fox DA, Rueda EM.

Invest Ophthalmol Vis Sci. 2015 Dec;56(13):8437. doi: 10.1167/iovs.15-18662. Review. No abstract available.

PMID:
26747774
42.

Retinal and visual system: occupational and environmental toxicology.

Fox DA.

Handb Clin Neurol. 2015;131:325-40. doi: 10.1016/B978-0-444-62627-1.00017-2. Review.

PMID:
26563796
43.

Activation of the Thromboxane A2 Receptor by 8-Isoprostane Inhibits the Pro-Angiogenic Effect of Vascular Endothelial Growth Factor in Scleroderma.

Tsou PS, Amin MA, Campbell PL, Zakhem G, Balogh B, Edhayan G, Ohara RA, Schiopu E, Khanna D, Koch AE, Fox DA.

J Invest Dermatol. 2015 Dec;135(12):3153-3162. doi: 10.1038/jid.2015.323. Epub 2015 Aug 19.

44.

Citrullination: A Specific Target for the Autoimmune Response in Rheumatoid Arthritis.

Fox DA.

J Immunol. 2015 Jul 1;195(1):5-7. doi: 10.4049/jimmunol.1501021. No abstract available.

45.

Killer B lymphocytes and their fas ligand positive exosomes as inducers of immune tolerance.

Lundy SK, Klinker MW, Fox DA.

Front Immunol. 2015 Mar 20;6:122. doi: 10.3389/fimmu.2015.00122. eCollection 2015.

46.

The incidence of upper and lower extremity surgery for rheumatoid arthritis among Medicare beneficiaries.

Waljee J, Zhong L, Baser O, Yuce H, Fox DA, Chung KC.

J Bone Joint Surg Am. 2015 Mar 4;97(5):403-10. doi: 10.2106/JBJS.N.00802.

47.

Variation in rheumatoid hand and wrist surgery among medicare beneficiaries: a population-based cohort study.

Zhong L, Chung KC, Baser O, Fox DA, Yuce H, Waljee JF.

J Rheumatol. 2015 Mar;42(3):429-36. doi: 10.3899/jrheum.140658. Epub 2015 Jan 15.

48.

Hyperthyroidism hidden by congenital central hypoventilation syndrome.

Fox DA, Weese-Mayer DE, Wensley DF, Stewart LL.

J Pediatr Endocrinol Metab. 2015 May;28(5-6):705-8. doi: 10.1515/jpem-2014-0174.

PMID:
25581741
49.

Inflammatory properties of inhibitor of DNA binding 1 secreted by synovial fibroblasts in rheumatoid arthritis.

Edhayan G, Ohara RA, Stinson WA, Amin MA, Isozaki T, Ha CM, Haines GK 3rd, Morgan R, Campbell PL, Arbab AS, Friday SC, Fox DA, Ruth JH.

Arthritis Res Ther. 2016 Apr 12;18:87. doi: 10.1186/s13075-016-0984-3.

50.

Loss of SH3 domain-binding protein 2 function suppresses bone destruction in tumor necrosis factor-driven and collagen-induced arthritis in mice.

Mukai T, Gallant R, Ishida S, Kittaka M, Yoshitaka T, Fox DA, Morita Y, Nishida K, Rottapel R, Ueki Y.

Arthritis Rheumatol. 2015 Mar;67(3):656-67. doi: 10.1002/art.38975.

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