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An improved platform for functional assessment of large protein libraries in mammalian cells.

Matreyek KA, Stephany JJ, Chiasson MA, Hasle N, Fowler DM.

Nucleic Acids Res. 2019 Oct 15. pii: gkz910. doi: 10.1093/nar/gkz910. [Epub ahead of print]


Elucidating the Molecular Determinants of Αβ Aggregation with Deep Mutational Scanning.

Gray VE, Sitko K, Kameni FZN, Williamson M, Stephany JJ, Hasle N, Fowler DM.

G3 (Bethesda). 2019 Sep 26. pii: g3.400535.2019. doi: 10.1534/g3.119.400535. [Epub ahead of print]


A Pilot Study Comparing Postmortem and Antemortem CT for the Identification of Unknowns: Could a Forensic Pathologist Do It?

Ali Z, Mourtzinos N, Ali BB, Fowler DR.

J Forensic Sci. 2019 Sep 26. doi: 10.1111/1556-4029.14199. [Epub ahead of print]


Interrogation of CYP2D6 structural variant alleles improves the correlation between CYP2D6 genotype and CYP2D6-mediated metabolic activity.

Dalton R, Lee SB, Claw KG, Prasad B, Phillips BR, Shen DD, Hong Wong L, Fade M, McDonald MG, Dunham MJ, Fowler DM, Rettie AE, Schuetz E, Thornton TA, Nickerson DA, Gaedigk A, Thummel KE, Woodahl EL.

Clin Transl Sci. 2019 Sep 19. doi: 10.1111/cts.12695. [Epub ahead of print]


Sub-decibel silicon grating couplers based on L-shaped waveguides and engineered subwavelength metamaterials.

Benedikovic D, Alonso-Ramos C, Guerber S, Le Roux X, Cheben P, Dupré C, Szelag B, Fowler D, Cassan É, Marris-Morini D, Baudot C, Boeuf F, Vivien L.

Opt Express. 2019 Sep 2;27(18):26239-26250. doi: 10.1364/OE.27.026239.


Prospective Study of a Novel, Radiation-Free, Reduced-Intensity Bone Marrow Transplantation Platform for Primary Immunodeficiency Diseases.

Dimitrova D, Gea-Banacloche J, Steinberg SM, Sadler JL, Hicks SN, Carroll E, Wilder JS, Parta M, Skeffington L, Hughes TE, Blau JE, Broadney MM, Rose JJ, Hsu AP, Fletcher R, Nunes NS, Yan XY, Telford WG, Kapoor V, Cohen JI, Freeman AF, Garabedian E, Holland SM, Lisco A, Malech HL, Notarangelo LD, Sereti I, Shah NN, Uzel G, Zerbe CS, Fowler DH, Gress RE, Kanakry CG, Kanakry JA.

Biol Blood Marrow Transplant. 2019 Sep 4. pii: S1083-8791(19)30558-0. doi: 10.1016/j.bbmt.2019.08.018. [Epub ahead of print]


A contingency management intervention to reduce cannabis use and time to relapse in early psychosis: the CIRCLE RCT.

Johnson S, Rains LS, Marwaha S, Strang J, Craig T, Weaver T, McCrone P, King M, Fowler D, Pilling S, Marston L, Omar RZ, Craig M, Spencer J, Hinton M.

Health Technol Assess. 2019 Aug;23(45):1-108. doi: 10.3310/hta23450.


Intimate Partner Violence Before and During Pregnancy, and Prenatal Counseling Among Women with a Recent Live Birth, United States, 2009-2015.

Kapaya M, Boulet SL, Warner L, Harrison L, Fowler D.

J Womens Health (Larchmt). 2019 Aug 28. doi: 10.1089/jwh.2018.7545. [Epub ahead of print]


The Impact of Genetic Variants on PTEN Molecular Functions and Cellular Phenotypes.

Hasle N, Matreyek KA, Fowler DM.

Cold Spring Harb Perspect Med. 2019 Aug 26. pii: a036228. doi: 10.1101/cshperspect.a036228. [Epub ahead of print]


Clinical and cost-effectiveness of contingency management for cannabis use in early psychosis: the CIRCLE randomised clinical trial.

Sheridan Rains L, Marston L, Hinton M, Marwaha S, Craig T, Fowler D, King M, Omar RZ, McCrone P, Spencer J, Taylor J, Colman S, Harder C, Gilbert E, Randhawa A, Labuschagne K, Jones C, Stefanidou T, Christoforou M, Craig M, Strang J, Weaver T, Johnson S.

BMC Med. 2019 Aug 15;17(1):161. doi: 10.1186/s12916-019-1395-5.


Measuring adherence in social recovery therapy with people with first episode psychosis.

Lowen C, Hodgekins J, Pugh K, Berry C, Fitzsimmons M, French P, Sacadura C, Birchwood M, Jackson C, Baggott E, Bernard M, Fowler D.

Behav Cogn Psychother. 2019 Aug 5:1-9. doi: 10.1017/S1352465819000432. [Epub ahead of print]


Genome-Wide Identification and Characterization of the Wheat Remorin (TaREM) Family during Cold Acclimation.

Badawi MA, Agharbaoui Z, Zayed M, Li Q, Byrns B, Zou J, Fowler DB, Danyluk J, Sarhan F.

Plant Genome. 2019 Jun;12(2). doi: 10.3835/plantgenome2018.06.0040.


Study protocol for a randomised controlled trial of CBT vs antipsychotics vs both in 14-18-year-olds: Managing Adolescent first episode Psychosis: a feasibility study (MAPS).

Pyle M, Broome MR, Joyce E, MacLennan G, Norrie J, Freeman D, Fowler D, Haddad PM, Shiers D, Hollis C, Smith J, Liew A, Byrne RE, French P, Peters S, Hudson J, Davies L, Emsley R, Yung A, Birchwood M, Longden E, Morrison AP.

Trials. 2019 Jul 4;20(1):395. doi: 10.1186/s13063-019-3506-1.


Development of a new reproductive tissue cryopreservation clinical service for children: the Oxford programme.

Lakhoo K, Davies J, Chakraborty S, Berg S, Tennyson R, Fowler D, Manek S, Verrill C, Lane S.

Pediatr Surg Int. 2019 Nov;35(11):1271-1278. doi: 10.1007/s00383-019-04503-3. Epub 2019 Jul 2.


Mutagenesis-based protein structure determination.

Chiasson M, Fowler DM.

Nat Genet. 2019 Jul;51(7):1072-1073. doi: 10.1038/s41588-019-0461-4. No abstract available.


Assessing social recovery of vulnerable youth in global mental health settings: a pilot study of clinical research tools in Malaysia.

Berry C, Othman E, Tan JC, Gee B, Byrne RE, Hodgekins J, Michelson D, Ng ALO, Marsh NV, Coker S, Fowler D.

BMC Psychiatry. 2019 Jun 20;19(1):188. doi: 10.1186/s12888-019-2164-x.


Applying Multiplex Assays to Understand Variation in Pharmacogenes.

Chiasson M, Dunham MJ, Rettie AE, Fowler DM.

Clin Pharmacol Ther. 2019 Aug;106(2):290-294. doi: 10.1002/cpt.1468. Epub 2019 May 30. No abstract available.


Psychological interventions for people with psychotic experiences: protocol for a systematic review and meta-analysis.

Soneson E, Russo D, Knight C, Lafortune L, Heslin M, Stochl J, Georgiadis A, Galante J, Duschinsky R, Grey N, Gonzalez-Blanco L, Couche J, Griffiths M, Murray H, Reeve N, Hodgekins J, French P, Fowler D, Byford S, Dixon-Woods M, Jones PB, Perez J.

Syst Rev. 2019 May 23;8(1):124. doi: 10.1186/s13643-019-1041-5.


Views of young people in Malaysia on mental health, help-seeking and unusual psychological experiences.

Berry C, Michelson D, Othman E, Tan JC, Gee B, Hodgekins J, Byrne RE, Ng ALO, Marsh NV, Coker S, Fowler D.

Early Interv Psychiatry. 2019 May 21. doi: 10.1111/eip.12832. [Epub ahead of print]


Chemical Derivatization Enables MALDI-TOF-Based High-Throughput Screening for Microbial Trimethylamine (TMA)-Lyase Inhibitors.

Winter M, Bretschneider T, Thamm S, Kleiner C, Grabowski D, Chandler S, Ries R, Kley JT, Fowler D, Bartlett C, Binetti R, Broadwater J, Luippold AH, Bischoff D, Büttner FH.

SLAS Discov. 2019 Aug;24(7):766-777. doi: 10.1177/2472555219838216. Epub 2019 May 6.


Three-Year Follow-Up Study Exploring Metacognition and Function in Individuals With First Episode Psychosis.

Wright AC, Davies G, Fowler D, Greenwood K.

Front Psychiatry. 2019 Apr 12;10:182. doi: 10.3389/fpsyt.2019.00182. eCollection 2019.


Faecal volatile biomarkers of Clostridium difficile infection.

Patel M, Fowler D, Sizer J, Walton C.

PLoS One. 2019 Apr 15;14(4):e0215256. doi: 10.1371/journal.pone.0215256. eCollection 2019.


A Combined Approach Reveals a Regulatory Mechanism Coupling Src's Kinase Activity, Localization, and Phosphotransferase-Independent Functions.

Ahler E, Register AC, Chakraborty S, Fang L, Dieter EM, Sitko KA, Vidadala RSR, Trevillian BM, Golkowski M, Gelman H, Stephany JJ, Rubin AF, Merritt EA, Fowler DM, Maly DJ.

Mol Cell. 2019 Apr 18;74(2):393-408.e20. doi: 10.1016/j.molcel.2019.02.003. Epub 2019 Apr 4.


Structured activity and multiple group memberships as mechanisms of increased depression amongst young people not in employment, education or training.

Berry C, Easterbrook MJ, Empson L, Fowler D.

Early Interv Psychiatry. 2019 Mar 29. doi: 10.1111/eip.12798. [Epub ahead of print]


SiN integrated optical phased arrays for two-dimensional beam steering at a single near-infrared wavelength.

Tyler NA, Fowler D, Malhouitre S, Garcia S, Grosse P, Rabaud W, Szelag B.

Opt Express. 2019 Feb 18;27(4):5851-5858. doi: 10.1364/OE.27.005851.


Biophysical and Mechanistic Models for Disease-Causing Protein Variants.

Stein A, Fowler DM, Hartmann-Petersen R, Lindorff-Larsen K.

Trends Biochem Sci. 2019 Jul;44(7):575-588. doi: 10.1016/j.tibs.2019.01.003. Epub 2019 Jan 31. Review.


Geographic variation and trends in opioid-involved crash deaths in Maryland: 2006-2017.

Duren M, Ehsani J, Grant B, Fowler D.

Accid Anal Prev. 2019 Apr;125:1-6. doi: 10.1016/j.aap.2019.01.012. Epub 2019 Jan 25.


Predicted Benign and Synonymous Variants in CYP11A1 Cause Primary Adrenal Insufficiency Through Missplicing.

Maharaj A, Buonocore F, Meimaridou E, Ruiz-Babot G, Guasti L, Peng HM, Capper CP, Burgos-Tirado N, Prasad R, Hughes CR, Maudhoo A, Crowne E, Cheetham TD, Brain CE, Suntharalingham JP, Striglioni N, Yuksel B, Gurbuz F, Gupta S, Lindsay R, Couch R, Spoudeas HA, Guran T, Johnson S, Fowler DJ, Conwell LS, McInerney-Leo AM, Drui D, Cariou B, Lopez-Siguero JP, Harris M, Duncan EL, Hindmarsh PC, Auchus RJ, Donaldson MD, Achermann JC, Metherell LA.

J Endocr Soc. 2018 Oct 30;3(1):201-221. doi: 10.1210/js.2018-00130. eCollection 2019 Jan 1.


Correction to: The U&I study: study protocol for a feasibility randomised controlled trial of a pre-cognitive behavioural therapy digital 'informed choice' intervention to improve attitudes towards uptake and implementation of CBT for psychosis.

Greenwood K, Alford K, O'Leary I, Peters E, Hardy A, Cavanagh K, Field AP, de Visser R, Fowler D, Davies M, Papamichail A, Garety P.

Trials. 2018 Dec 12;19(1):677. doi: 10.1186/s13063-018-3085-6.


How Inclusive, User-Centered Design Research Can Improve Psychological Therapies for Psychosis: Development of SlowMo.

Hardy A, Wojdecka A, West J, Matthews E, Golby C, Ward T, Lopez ND, Freeman D, Waller H, Kuipers E, Bebbington P, Fowler D, Emsley R, Dunn G, Garety P.

JMIR Ment Health. 2018 Dec 5;5(4):e11222. doi: 10.2196/11222.


Multiplane Intracardiac Echocardiography: A Novel System to Guide Percutaneous Tricuspid Repair.

Robinson AA, Chadwell K, Fowler DE, Ailawadi G, Lim DS.

JACC Cardiovasc Interv. 2018 Dec 24;11(24):2540-2542. doi: 10.1016/j.jcin.2018.09.039. Epub 2018 Nov 28. No abstract available.


A rare presentation of a paediatric sinonasal inverted papilloma.

Jayakody N, Ward M, Wijayasingham G, Fowler D, Harries P, Salib R.

J Surg Case Rep. 2018 Nov 30;2018(11):rjy321. doi: 10.1093/jscr/rjy321. eCollection 2018 Nov.


The U&I study: study protocol for a feasibility randomised controlled trial of a pre-cognitive behavioural therapy digital 'informed choice' intervention to improve attitudes towards uptake and implementation of CBT for psychosis.

Greenwood K, Alford K, O'Leary I, Peters E, Hardy A, Cavanagh K, Field AP, de Visser R, Fowler D, Davies M, Papamichail A, Garety P.

Trials. 2018 Nov 20;19(1):644. doi: 10.1186/s13063-018-3023-7. Erratum in: Trials. 2018 Dec 12;19(1):677.


Amyloid β toxic conformer has dynamic localization in the human inferior parietal cortex in absence of amyloid plaques.

Kageyama Y, Saito A, Pletnikova O, Rudow GL, Irie Y, An Y, Murakami K, Irie K, Resnick SM, Fowler DR, Martin LJ, Troncoso JC.

Sci Rep. 2018 Nov 15;8(1):16895. doi: 10.1038/s41598-018-35004-3.


Self-defining Memories Predict Engagement in Structured Activity in First Episode Psychosis, Independent of Neurocognition and Metacognition.

Wright AC, Davies G, Fowler D, Greenwood KE.

Schizophr Bull. 2019 Sep 11;45(5):1081-1091. doi: 10.1093/schbul/sby155.


Transfusion support for matched sibling allogeneic hematopoietic stem cell transplantation (1993-2010): factors that predict intensity and time to transfusion independence.

Griffith LM, VanRaden M, Barrett AJ, Childs RW, Fowler DH, Kang EM, Tisdale JF, Klein HG, Stroncek DF.

Transfusion. 2019 Jan;59(1):303-315. doi: 10.1111/trf.14966. Epub 2018 Oct 26.


Cytomegalovirus Infection Incidence and Risk Factors Across Diverse Hematopoietic Cell Transplantation Platforms Using a Standardized Monitoring and Treatment Approach: A Comprehensive Evaluation from a Single Institution.

Melendez-Munoz R, Marchalik R, Jerussi T, Dimitrova D, Nussenblatt V, Beri A, Rai K, Wilder JS, Barrett AJ, Battiwalla M, Childs RW, Fitzhugh CD, Fowler DH, Fry TJ, Gress RE, Hsieh MM, Ito S, Kang EM, Pavletic SZ, Shah NN, Tisdale JF, Gea-Banacloche J, Kanakry CG, Kanakry JA.

Biol Blood Marrow Transplant. 2019 Mar;25(3):577-586. doi: 10.1016/j.bbmt.2018.10.011. Epub 2018 Oct 18.


Ice segregation in the crown of winter cereals: Evidence for extraorgan and extratissue freezing.

Willick IR, Gusta LV, Fowler DB, Tanino KK.

Plant Cell Environ. 2019 Feb;42(2):701-716. doi: 10.1111/pce.13454. Epub 2018 Nov 19.


Short-term outcome of first episode delusional disorder in an early intervention population.

Rowland T, Birchwood M, Singh S, Freemantle N, Everard L, Jones P, Fowler D, Amos T, Marshall M, Sharma V, Thompson A.

Schizophr Res. 2019 Feb;204:72-79. doi: 10.1016/j.schres.2018.08.036. Epub 2018 Sep 6.


Dead in the water: Epilepsy-related drowning or sudden unexpected death in epilepsy?

Cihan E, Hesdorffer DC, Brandsoy M, Li L, Fowler DR, Graham JK, Donner EJ, Devinsky O, Friedman D.

Epilepsia. 2018 Oct;59(10):1966-1972. doi: 10.1111/epi.14546. Epub 2018 Aug 26.


A multi-isotope (δ13C, δ15N, δ34S, δ2H) approach to establishing migratory connectivity in lesser snow geese: Tracking an overabundant species.

Fowler DN, Webb EB, Baldwin FB, Vrtiska MP, Hobson KA.

PLoS One. 2018 Aug 24;13(8):e0203077. doi: 10.1371/journal.pone.0203077. eCollection 2018.


Sleep duration and psychotic experiences in patients at risk of psychosis: A secondary analysis of the EDIE-2 trial.

Reeve S, Nickless A, Sheaves B, Hodgekins J, Stewart SLK, Gumley A, Fowler D, Morrison A, Freeman D.

Schizophr Res. 2019 Feb;204:326-333. doi: 10.1016/j.schres.2018.08.006. Epub 2018 Aug 16.


Wandering spleen caused by subcapsular haemorrhage.

Kariya CM, Fowler DH, Stratton P.

BMJ Case Rep. 2018 Aug 16;2018. pii: bcr-2018-224917. doi: 10.1136/bcr-2018-224917. No abstract available.


The spectrum of preclinical Alzheimer's disease pathology and its modulation by ApoE genotype.

Pletnikova O, Kageyama Y, Rudow G, LaClair KD, Albert M, Crain BJ, Tian J, Fowler D, Troncoso JC.

Neurobiol Aging. 2018 Nov;71:72-80. doi: 10.1016/j.neurobiolaging.2018.07.007. Epub 2018 Jul 19.


Impact of the 2014 NIH chronic graft-versus-host disease scoring criteria modifications assessed in a large cohort of severely affected patients.

Kerep AZ, Broome J, Pirsl F, Curtis LM, Steinberg SM, Mitchell SA, Cowen EW, Pichard DC, Joe GO, Comis LE, Mays JW, Datiles MB 3rd, Stratton P, Zolton J, Berger A, Hendricks J, Kenyon M, Baruffaldi J, Titarenko I, Pulanic D, Baird K, Fowler DH, Gress RE, Pavletic SZ.

Bone Marrow Transplant. 2019 Jan;54(1):76-84. doi: 10.1038/s41409-018-0224-3. Epub 2018 Aug 8.


PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells.

Stathopoulou C, Gangaplara A, Mallett G, Flomerfelt FA, Liniany LP, Knight D, Samsel LA, Berlinguer-Palmini R, Yim JJ, Felizardo TC, Eckhaus MA, Edgington-Mitchell L, Martinez-Fabregas J, Zhu J, Fowler DH, van Kasteren SI, Laurence A, Bogyo M, Watts C, Shevach EM, Amarnath S.

Immunity. 2018 Aug 21;49(2):247-263.e7. doi: 10.1016/j.immuni.2018.05.006. Epub 2018 Jul 24.


Persecutory delusions: effects of Cognitive Bias Modification for Interpretation and the Maudsley Review Training Programme on social anxiety, jumping to conclusions, belief inflexibility and paranoia.

Hurley J, Hodgekins J, Coker S, Fowler D.

J Behav Ther Exp Psychiatry. 2018 Dec;61:14-23. doi: 10.1016/j.jbtep.2018.05.003. Epub 2018 May 9.


Postmortem Genetic Testing for Cardiac Ion Channelopathies in Stillbirths.

Munroe PB, Addison S, Abrams DJ, Sebire NJ, Cartwright J, Donaldson I, Cohen MM, Mein C, Tinker A, Harmer SC, Aziz Q, Terry A, Struebig M, Warren HR, Vadgama B, Fowler DJ, Peebles D, Taylor AM, Lally PJ, Thayyil S.

Circ Genom Precis Med. 2018 Jan;11(1):e001817. doi: 10.1161/CIRCGEN.117.001817. Epub 2018 Jan 11.


Quantitative measurement of lipid rich plaque by coronary computed tomography angiography: A correlation of histology in sudden cardiac death.

Han D, Torii S, Yahagi K, Lin FY, Lee JH, Rizvi A, Gransar H, Park MW, Roudsari HM, Stuijfzand WJ, Baskaran L, Ó Hartaigh B, Park HB, Lee SE, Ali Z, Kutys R, Chang HJ, Earls JP, Fowler D, Virmani R, Min JK.

Atherosclerosis. 2018 Aug;275:426-433. doi: 10.1016/j.atherosclerosis.2018.05.024. Epub 2018 May 21.


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