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Role of pannexin-1 in the cellular uptake, release and hydrolysis of anandamide by T84 colon cancer cells.

Alhouayek M, Sorti R, Gilthorpe JD, Fowler CJ.

Sci Rep. 2019 May 20;9(1):7622. doi: 10.1038/s41598-019-44057-x.


Low mRNA expression and activity of monoacylglycerol lipase in human SH-SY5Y neuroblastoma cells.

Szeremeta J, Karlsson J, Alhouayek M, Fowler CJ.

Prostaglandins Other Lipid Mediat. 2019 Jun;142:59-67. doi: 10.1016/j.prostaglandins.2019.04.003. Epub 2019 Apr 9.


Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors.

Deplano A, Cipriano M, Moraca F, Novellino E, Catalanotti B, Fowler CJ, Onnis V.

J Enzyme Inhib Med Chem. 2019 Dec;34(1):562-576. doi: 10.1080/14756366.2018.1532418.


Performance of Litholyme™ compared with Sodasorb™ carbon dioxide absorbents in a standard clinical setting.

Fowler CJ, Burbridge MA, Jaffe RA, Brock-Utne JG.

Br J Anaesth. 2019 Jan;122(1):e11-e12. doi: 10.1016/j.bja.2018.09.015. Epub 2018 Nov 2. No abstract available.


Satiety Factors Oleoylethanolamide, Stearoylethanolamide, and Palmitoylethanolamide in Mother's Milk Are Strongly Associated with Infant Weight at Four Months of Age-Data from the Odense Child Cohort.

Bruun S, Gouveia-Figueira S, Domellöf M, Husby S, Neergaard Jacobsen L, Michaelsen KF, Fowler CJ, Zachariassen G.

Nutrients. 2018 Nov 13;10(11). pii: E1747. doi: 10.3390/nu10111747.


TNF overproduction impairs epithelial staphylococcal response in hyper IgE syndrome.

Myles IA, Anderson ED, Earland NJ, Zarember KA, Sastalla I, Williams KW, Gough P, Moore IN, Ganesan S, Fowler CJ, Laurence A, Garofalo M, Kuhns DB, Kieh MD, Saleem A, Welch PA, Darnell DA, Gallin JI, Freeman AF, Holland SM, Datta SK.

J Clin Invest. 2018 Aug 1;128(8):3595-3604. doi: 10.1172/JCI121486. Epub 2018 Jul 23.


Differences in Swedish and Australian medical student attitudes and beliefs about chronic pain, its management, and the way it is taught.

Rankin L, Stålnacke BM, Fowler CJ, Gallego G.

Scand J Pain. 2018 Jul 26;18(3):533-544. doi: 10.1515/sjpain-2018-0039.


CSF Tau supplements 14-3-3 protein detection for sporadic Creutzfeldt-Jakob disease diagnosis while transitioning to next generation diagnostics.

Li QX, Varghese S, Sarros S, Stehmann C, Doecke JD, Fowler CJ, Masters CL, Collins SJ.

J Clin Neurosci. 2018 Apr;50:292-293. doi: 10.1016/j.jocn.2018.01.064.


Association of β-Amyloid and Apolipoprotein E ε4 With Memory Decline in Preclinical Alzheimer Disease.

Lim YY, Kalinowski P, Pietrzak RH, Laws SM, Burnham SC, Ames D, Villemagne VL, Fowler CJ, Rainey-Smith SR, Martins RN, Rowe CC, Masters CL, Maruff PT.

JAMA Neurol. 2018 Apr 1;75(4):488-494. doi: 10.1001/jamaneurol.2017.4325.


Interferon γ treatment increases endocannabinoid and related N-acylethanolamine levels in T84 human colon carcinoma cells.

Alhouayek M, Rankin L, Gouveia-Figueira S, Fowler CJ.

Br J Pharmacol. 2019 May;176(10):1470-1480. doi: 10.1111/bph.14135. Epub 2018 Feb 5.


Involvement of CYP1B1 in interferon γ-induced alterations of epithelial barrier integrity.

Alhouayek M, Gouveia-Figueira S, Hammarström ML, Fowler CJ.

Br J Pharmacol. 2018 Mar;175(6):877-890. doi: 10.1111/bph.14122. Epub 2018 Feb 4.


Concordance Between Cerebrospinal Fluid Biomarkers with Alzheimer's Disease Pathology Between Three Independent Assay Platforms.

Doecke JD, Rembach A, Villemagne VL, Varghese S, Rainey-Smith S, Sarros S, Evered LA, Fowler CJ, Pertile KK, Rumble RL, Trounson B, Taddei K, Laws SM, Macaulay SL, Bush AI, Ellis KA, Martins R, Ames D, Silbert B, Vanderstichele H, Masters CL, Darby DG, Li QX, Collins S; AIBL Research Group.

J Alzheimers Dis. 2018;61(1):169-183. doi: 10.3233/JAD-170128.


TLR4 receptor expression and function in F11 dorsal root ganglion × neuroblastoma hybrid cells.

Hashemian S, Alhouayek M, Fowler CJ.

Innate Immun. 2017 Nov;23(8):687-696. doi: 10.1177/1753425917732824. Epub 2017 Sep 29.


Effects of tumour necrosis factor α upon the metabolism of the endocannabinoid anandamide in prostate cancer cells.

Karlsson J, Gouveia-Figueira S, Alhouayek M, Fowler CJ.

PLoS One. 2017 Sep 14;12(9):e0185011. doi: 10.1371/journal.pone.0185011. eCollection 2017.


Endocannabinoid Turnover.

Fowler CJ, Doherty P, Alexander SPH.

Adv Pharmacol. 2017;80:31-66. doi: 10.1016/bs.apha.2017.03.006. Epub 2017 May 25. Review.


Assessing the Collective Dynamics of Motile Cilia in Cultures of Human Airway Cells by Multiscale DDM.

Feriani L, Juenet M, Fowler CJ, Bruot N, Chioccioli M, Holland SM, Bryant CE, Cicuta P.

Biophys J. 2017 Jul 11;113(1):109-119. doi: 10.1016/j.bpj.2017.05.028.


Reduced TRPC6 mRNA levels in the blood cells of patients with Alzheimer's disease and mild cognitive impairment.

Lu R, Wang J, Tao R, Wang J, Zhu T, Guo W, Sun Y, Li H, Gao Y, Zhang W, Fowler CJ, Li Q, Chen S, Wu Z, Masters CL, Zhong C, Jing N, Wang Y, Wang Y.

Mol Psychiatry. 2018 Mar;23(3):767-776. doi: 10.1038/mp.2017.136. Epub 2017 Jul 11.


Levels of oxylipins, endocannabinoids and related lipids in plasma before and after low-level exposure to acrolein in healthy individuals and individuals with chemical intolerance.

Claeson AS, Gouveia-Figueira S, Häggström J, Fowler CJ, Nording ML.

Prostaglandins Leukot Essent Fatty Acids. 2017 Jun;121:60-67. doi: 10.1016/j.plefa.2017.06.004. Epub 2017 Jun 15.


Novel propanamides as fatty acid amide hydrolase inhibitors.

Deplano A, Morgillo CM, Demurtas M, Björklund E, Cipriano M, Svensson M, Hashemian S, Smaldone G, Pedone E, Luque FJ, Cabiddu MG, Novellino E, Fowler CJ, Catalanotti B, Onnis V.

Eur J Med Chem. 2017 Aug 18;136:523-542. doi: 10.1016/j.ejmech.2017.05.033. Epub 2017 May 12.


Plasma levels of the endocannabinoid anandamide, related N-acylethanolamines and linoleic acid-derived oxylipins in patients with migraine.

Gouveia-Figueira S, Goldin K, Hashemian SA, Lindberg A, Persson M, Nording ML, Laurell K, Fowler CJ.

Prostaglandins Leukot Essent Fatty Acids. 2017 May;120:15-24. doi: 10.1016/j.plefa.2017.04.005. Epub 2017 Apr 21.


Sulfotransferase 1A3/4 copy number variation is associated with neurodegenerative disease.

Butcher NJ, Horne MK, Mellick GD, Fowler CJ, Masters CL; AIBL research group, Minchin RF.

Pharmacogenomics J. 2018 Apr;18(2):209-214. doi: 10.1038/tpj.2017.4. Epub 2017 Apr 4.


The anti-inflammatory compound palmitoylethanolamide inhibits prostaglandin and hydroxyeicosatetraenoic acid production by a macrophage cell line.

Gabrielsson L, Gouveia-Figueira S, Häggström J, Alhouayek M, Fowler CJ.

Pharmacol Res Perspect. 2017 Feb 27;5(2):e00300. doi: 10.1002/prp2.300. eCollection 2017 Apr.


Selenium Levels in Serum, Red Blood Cells, and Cerebrospinal Fluid of Alzheimer's Disease Patients: A Report from the Australian Imaging, Biomarker & Lifestyle Flagship Study of Ageing (AIBL).

Cardoso BR, Hare DJ, Bush AI, Li QX, Fowler CJ, Masters CL, Martins RN, Ganio K, Lothian A, Mukherjee S, Kapp EA, Roberts BR; AIBL research group.

J Alzheimers Dis. 2017;57(1):183-193. doi: 10.3233/JAD-160622.


N-aryl 2-aryloxyacetamides as a new class of fatty acid amide hydrolase (FAAH) inhibitors.

Sunduru N, Svensson M, Cipriano M, Marwaha S, Andersson CD, Svensson R, Fowler CJ, Elofsson M.

J Enzyme Inhib Med Chem. 2017 Dec;32(1):513-521. doi: 10.1080/14756366.2016.1265520.


Rubidium and potassium levels are altered in Alzheimer's disease brain and blood but not in cerebrospinal fluid.

Roberts BR, Doecke JD, Rembach A, Yévenes LF, Fowler CJ, McLean CA, Lind M, Volitakis I, Masters CL, Bush AI, Hare DJ; AIBL research group.

Acta Neuropathol Commun. 2016 Nov 14;4(1):119.


Palmitoylethanolamide for the treatment of pain: pharmacokinetics, safety and efficacy.

Gabrielsson L, Mattsson S, Fowler CJ.

Br J Clin Pharmacol. 2016 Oct;82(4):932-42. doi: 10.1111/bcp.13020. Epub 2016 Jun 29. Review.


Association between plasma concentrations of linoleic acid-derived oxylipins and the perceived pain scores in an exploratory study in women with chronic neck pain.

Hellström F, Gouveia-Figueira S, Nording ML, Björklund M, Fowler CJ.

BMC Musculoskelet Disord. 2016 Feb 25;17:103. doi: 10.1186/s12891-016-0951-9.


Alzheimer's disease cerebrospinal fluid biomarkers are not influenced by gravity drip or aspiration extraction methodology.

Rembach A, Evered LA, Li QX, Nash T, Vidaurre L, Fowler CJ, Pertile KK, Rumble RL, Trounson BO, Maher S, Mooney F, Farrow M, Taddei K, Rainey-Smith S, Laws SM, Macaulay SL, Wilson W, Darby DG, Martins RN, Ames D, Collins S, Silbert B, Masters CL, Doecke JD; AIBL Research Group.

Alzheimers Res Ther. 2015 Nov 19;7(1):71. doi: 10.1186/s13195-015-0157-7.


Interaction of the N-(3-Methylpyridin-2-yl)amide Derivatives of Flurbiprofen and Ibuprofen with FAAH: Enantiomeric Selectivity and Binding Mode.

Karlsson J, Morgillo CM, Deplano A, Smaldone G, Pedone E, Luque FJ, Svensson M, Novellino E, Congiu C, Onnis V, Catalanotti B, Fowler CJ.

PLoS One. 2015 Nov 13;10(11):e0142711. doi: 10.1371/journal.pone.0142711. eCollection 2015.


Relative and absolute reliability of measures of linoleic acid-derived oxylipins in human plasma.

Gouveia-Figueira S, Bosson JA, Unosson J, Behndig AF, Nording ML, Fowler CJ.

Prostaglandins Other Lipid Mediat. 2015 Sep;121(Pt B):227-33. doi: 10.1016/j.prostaglandins.2015.10.003. Epub 2015 Oct 20.


Open-label study evaluating outpatient urethral sphincter injections of onabotulinumtoxinA to treat women with urinary retention due to a primary disorder of sphincter relaxation (Fowler's syndrome).

Panicker JN, Seth JH, Khan S, Gonzales G, Haslam C, Kessler TM, Fowler CJ.

BJU Int. 2016 May;117(5):809-13. doi: 10.1111/bju.13342. Epub 2015 Nov 8.


Endocannabinoids and related lipids in blood plasma following touch massage: a randomised, crossover study.

Lindgren L, Gouveia-Figueira S, Nording ML, Fowler CJ.

BMC Res Notes. 2015 Sep 29;8:504. doi: 10.1186/s13104-015-1450-z.


The Potential of Inhibitors of Endocannabinoid Metabolism for Drug Development: A Critical Review.

Fowler CJ.

Handb Exp Pharmacol. 2015;231:95-128. doi: 10.1007/978-3-319-20825-1_4. Review.


Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor.

Gouveia-Figueira S, Karlsson J, Deplano A, Hashemian S, Svensson M, Fredriksson Sundbom M, Congiu C, Onnis V, Fowler CJ.

PLoS One. 2015 Sep 25;10(9):e0139212. doi: 10.1371/journal.pone.0139212. eCollection 2015.


Alzheimer's Disease Normative Cerebrospinal Fluid Biomarkers Validated in PET Amyloid-β Characterized Subjects from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study.

Li QX, Villemagne VL, Doecke JD, Rembach A, Sarros S, Varghese S, McGlade A, Laughton KM, Pertile KK, Fowler CJ, Rumble RL, Trounson BO, Taddei K, Rainey-Smith SR, Laws SM, Robertson JS, Evered LA, Silbert B, Ellis KA, Rowe CC, Macaulay SL, Darby D, Martins RN, Ames D, Masters CL, Collins S; AIBL Research Group.

J Alzheimers Dis. 2015;48(1):175-87. doi: 10.3233/JAD-150247.


Zinc affects the proteolytic stability of Apolipoprotein E in an isoform-dependent way.

Xu H, Gupta VB, Martins IJ, Martins RN, Fowler CJ, Bush AI, Finkelstein DI, Adlard PA.

Neurobiol Dis. 2015 Sep;81:38-48. doi: 10.1016/j.nbd.2015.06.016. Epub 2015 Jun 25.


Lower urinary tract dysfunction in the neurological patient: clinical assessment and management.

Panicker JN, Fowler CJ, Kessler TM.

Lancet Neurol. 2015 Jul;14(7):720-32. doi: 10.1016/S1474-4422(15)00070-8. Review.


Pulmonary Nontuberculous Mycobacterial Infection. A Multisystem, Multigenic Disease.

Szymanski EP, Leung JM, Fowler CJ, Haney C, Hsu AP, Chen F, Duggal P, Oler AJ, McCormack R, Podack E, Drummond RA, Lionakis MS, Browne SK, Prevots DR, Knowles M, Cutting G, Liu X, Devine SE, Fraser CM, Tettelin H, Olivier KN, Holland SM.

Am J Respir Crit Care Med. 2015 Sep 1;192(5):618-28. doi: 10.1164/rccm.201502-0387OC.


Lower urinary tract dysfunction in patients with multiple sclerosis.

Panicker JN, Fowler CJ.

Handb Clin Neurol. 2015;130:371-81. doi: 10.1016/B978-0-444-63247-0.00021-3. Review.


Plant sources of antimuscarinics.

Fowler CJ.

BJU Int. 2015 Apr;115 Suppl 6:4-7. doi: 10.1111/bju.13074. No abstract available.


Serum levels of oxylipins in achilles tendinopathy: an exploratory study.

Gouveia-Figueira S, Nording ML, Gaida JE, Forsgren S, Alfredson H, Fowler CJ.

PLoS One. 2015 Apr 13;10(4):e0123114. doi: 10.1371/journal.pone.0123114. eCollection 2015.


Leptin levels are negatively correlated with 2-arachidonoylglycerol in the cerebrospinal fluid of patients with osteoarthritis.

Nicholson J, Azim S, Rebecchi MJ, Galbavy W, Feng T, Reinsel R, Rizwan S, Fowler CJ, Benveniste H, Kaczocha M.

PLoS One. 2015 Apr 2;10(4):e0123132. doi: 10.1371/journal.pone.0123132. eCollection 2015.


The potential of inhibitors of endocannabinoid metabolism as anxiolytic and antidepressive drugs--A practical view.

Fowler CJ.

Eur Neuropsychopharmacol. 2015 Jun;25(6):749-62. doi: 10.1016/j.euroneuro.2015.02.005. Epub 2015 Feb 28. Review.


Delta(9) -tetrahydrocannabinol and cannabidiol as potential curative agents for cancer: A critical examination of the preclinical literature.

Fowler CJ.

Clin Pharmacol Ther. 2015 Jun;97(6):587-96. doi: 10.1002/cpt.84. Epub 2015 May 2. Review.


Decreased plasma iron in Alzheimer's disease is due to transferrin desaturation.

Hare DJ, Doecke JD, Faux NG, Rembach A, Volitakis I, Fowler CJ, Grimm R, Doble PA, Cherny RA, Masters CL, Bush AI, Roberts BR.

ACS Chem Neurosci. 2015 Mar 18;6(3):398-402. doi: 10.1021/cn5003557. Epub 2015 Jan 23.


Peripheral α-defensins 1 and 2 are elevated in Alzheimer's disease.

Watt AD, Perez KA, Ang CS, O'Donnell P, Rembach A, Pertile KK, Rumble RL, Trounson BO, Fowler CJ, Faux NG, Masters CL, Villemagne VL, Barnham KJ.

J Alzheimers Dis. 2015;44(4):1131-43. doi: 10.3233/JAD-142286.


Prognostic serum miRNA biomarkers associated with Alzheimer's disease shows concordance with neuropsychological and neuroimaging assessment.

Cheng L, Doecke JD, Sharples RA, Villemagne VL, Fowler CJ, Rembach A, Martins RN, Rowe CC, Macaulay SL, Masters CL, Hill AF; Australian Imaging, Biomarkers and Lifestyle (AIBL) Research Group.

Mol Psychiatry. 2015 Oct;20(10):1188-96. doi: 10.1038/mp.2014.127. Epub 2014 Oct 28.


A reversible and selective inhibitor of monoacylglycerol lipase ameliorates multiple sclerosis.

Hernández-Torres G, Cipriano M, Hedén E, Björklund E, Canales Á, Zian D, Feliú A, Mecha M, Guaza C, Fowler CJ, Ortega-Gutiérrez S, López-Rodríguez ML.

Angew Chem Int Ed Engl. 2014 Dec 8;53(50):13765-70. doi: 10.1002/anie.201407807. Epub 2014 Oct 8.


ErbB2 receptor immunoreactivity in prostate cancer: relationship to the androgen receptor, disease severity at diagnosis and disease outcome.

Hammarsten P, Winther J, Rudolfsson SH, Häggström J, Karalija A, Egevad L, Granfors T, Fowler CJ.

PLoS One. 2014 Sep 12;9(9):e105063. doi: 10.1371/journal.pone.0105063. eCollection 2014.


Cannabidiol improves vasorelaxation in Zucker diabetic fatty rats through cyclooxygenase activation.

Wheal AJ, Cipriano M, Fowler CJ, Randall MD, O'Sullivan SE.

J Pharmacol Exp Ther. 2014 Nov;351(2):457-66. doi: 10.1124/jpet.114.217125. Epub 2014 Sep 11.


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