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Items: 38

1.

Corrigendum: Targeted NGS Platforms for Genetic Screening and Gene Discovery in Primary Immunodeficiencies.

Cifaldi C, Brigida I, Barzaghi F, Zoccolillo M, Ferradini V, Petricone D, Cicalese MP, Lazarevic D, Cittaro D, Omrani M, Attardi E, Conti F, Scarselli A, Chiriaco M, Di Cesare S, Licciardi F, Davide M, Ferrua F, Canessa C, Pignata C, Giliani S, Ferrari S, Fousteri G, Barera G, Merli P, Palma P, Cesaro S, Gattorno M, Trizzino A, Moschese V, Chini L, Villa A, Azzari C, Finocchi A, Locatelli F, Rossi P, Sangiuolo F, Aiuti A, Cancrini C, Di Matteo G.

Front Immunol. 2019 May 31;10:1184. doi: 10.3389/fimmu.2019.01184. eCollection 2019.

2.

Experimental colitis in IL-10-deficient mice ameliorates in the absence of PTPN22.

Jofra T, Galvani G, Cosorich I, De Giorgi L, Annoni A, Vecchione A, Sorini C, Falcone M, Fousteri G.

Clin Exp Immunol. 2019 Sep;197(3):263-275. doi: 10.1111/cei.13339. Epub 2019 Jul 10.

PMID:
31194881
3.

Targeted NGS Platforms for Genetic Screening and Gene Discovery in Primary Immunodeficiencies.

Cifaldi C, Brigida I, Barzaghi F, Zoccolillo M, Ferradini V, Petricone D, Cicalese MP, Lazarevic D, Cittaro D, Omrani M, Attardi E, Conti F, Scarselli A, Chiriaco M, Di Cesare S, Licciardi F, Davide M, Ferrua F, Canessa C, Pignata C, Giliani S, Ferrari S, Fousteri G, Barera G, Merli P, Palma P, Cesaro S, Gattorno M, Trizzino A, Moschese V, Chini L, Villa A, Azzari C, Finocchi A, Locatelli F, Rossi P, Sangiuolo F, Aiuti A, Cancrini C, Di Matteo G.

Front Immunol. 2019 Apr 11;10:316. doi: 10.3389/fimmu.2019.00316. eCollection 2019. Erratum in: Front Immunol. 2019 May 31;10:1184.

4.

Thymic Epithelium Abnormalities in DiGeorge and Down Syndrome Patients Contribute to Dysregulation in T Cell Development.

Marcovecchio GE, Bortolomai I, Ferrua F, Fontana E, Imberti L, Conforti E, Amodio D, Bergante S, Macchiarulo G, D'Oria V, Conti F, Di Cesare S, Fousteri G, Carotti A, Giamberti A, Poliani PL, Notarangelo LD, Cancrini C, Villa A, Bosticardo M.

Front Immunol. 2019 Mar 15;10:447. doi: 10.3389/fimmu.2019.00447. eCollection 2019.

5.

Type 1 Diabetes in STAT Protein Family Mutations: Regulating the Th17/Treg Equilibrium and Beyond.

Fabbri M, Frixou M, Degano M, Fousteri G.

Diabetes. 2019 Feb;68(2):258-265. doi: 10.2337/db18-0627.

6.

Circulating Follicular Helper and Follicular Regulatory T Cells Are Severely Compromised in Human CD40 Deficiency: A Case Report.

Cicalese MP, Gerosa J, Baronio M, Montin D, Licciardi F, Soresina A, Dellepiane RM, Miano M, Baselli LA, Volpi S, Dufour C, Plebani A, Aiuti A, Lougaris V, Fousteri G.

Front Immunol. 2018 Aug 6;9:1761. doi: 10.3389/fimmu.2018.01761. eCollection 2018.

7.

Tr1 cell immunotherapy promotes transplant tolerance via de novo Tr1 cell induction in mice and is safe and effective during acute viral infection.

Jofra T, Di Fonte R, Galvani G, Kuka M, Iannacone M, Battaglia M, Fousteri G.

Eur J Immunol. 2018 Aug;48(8):1389-1399. doi: 10.1002/eji.201747316. Epub 2018 May 30.

8.

Regulatory T-cells from pancreatic lymphnodes of patients with type-1 diabetes express increased levels of microRNA miR-125a-5p that limits CCR2 expression.

Sebastiani G, Ventriglia G, Stabilini A, Socci C, Morsiani C, Laurenzi A, Nigi L, Formichi C, Mfarrej B, Petrelli A, Fousteri G, Brusko TM, Dotta F, Battaglia M.

Sci Rep. 2017 Jul 31;7(1):6897. doi: 10.1038/s41598-017-07172-1.

9.

PTPN22 and islet-specific autoimmunity: What have the mouse models taught us?

Galvani G, Fousteri G.

World J Diabetes. 2017 Jul 15;8(7):330-336. doi: 10.4239/wjd.v8.i7.330. Review.

10.

Extrinsic Protein Tyrosine Phosphatase Non-Receptor 22 Signals Contribute to CD8 T Cell Exhaustion and Promote Persistence of Chronic Lymphocytic Choriomeningitis Virus Infection.

Jofra T, Galvani G, Kuka M, Di Fonte R, Mfarrej BG, Iannacone M, Salek-Ardakani S, Battaglia M, Fousteri G.

Front Immunol. 2017 Jul 12;8:811. doi: 10.3389/fimmu.2017.00811. eCollection 2017.

11.

Beta2 integrins are required for follicular helper T cell differentiation in humans.

Gerosa J, Lougaris V, Baronio M, Plebani A, Cicalese MP, Fousteri G.

Clin Immunol. 2017 Jul;180:60-62. doi: 10.1016/j.clim.2017.04.002. Epub 2017 Apr 6. No abstract available.

PMID:
28390967
12.

Protein tyrosine phosphatase PTPN22 has dual roles in promoting pathogen versus homeostatic-driven CD8 T-cell responses.

Jofra T, Di Fonte R, Hutchinson TE, Dastmalchi F, Galvani G, Battaglia M, Salek-Ardakani S, Fousteri G.

Immunol Cell Biol. 2017 Feb;95(2):121-128. doi: 10.1038/icb.2016.92. Epub 2016 Oct 11.

PMID:
27725666
13.

Transplant Site Influences the Immune Response After Islet Transplantation: Bone Marrow Versus Liver.

Cantarelli E, Citro A, Pellegrini S, Mercalli A, Melzi R, Dugnani E, Jofra T, Fousteri G, Mondino A, Piemonti L.

Transplantation. 2017 May;101(5):1046-1055. doi: 10.1097/TP.0000000000001462.

PMID:
27575689
14.

Beta-cell Specific Autoantibodies: Are they Just an Indicator of Type 1 Diabetes?

Fousteri G, Ippolito E, Ahmed R, Hamad ARA.

Curr Diabetes Rev. 2017;13(3):322-329. doi: 10.2174/1573399812666160427104157. Review.

15.

B cell-targeted immunotherapy for type 1 diabetes: What can make it work?

Hamad AR, Ahmed R, Donner T, Fousteri G.

Discov Med. 2016 Mar;21(115):213-9. Review.

16.

Reduced germinal center follicular helper T cells but normal follicular regulatory T cells in the tonsils of a patient with a mutation in the PI3KR1 gene.

Di Fonte R, Baronio M, Plebani A, Lougaris V, Fousteri G.

Clin Immunol. 2016 Mar;164:43-4. doi: 10.1016/j.clim.2016.01.016. Epub 2016 Jan 28. No abstract available.

PMID:
26827886
17.

Combination of an Antigen-Specific Therapy and an Immunomodulatory Treatment to Simultaneous Block Recurrent Autoimmunity and Alloreactivity in Non-Obese Diabetic Mice.

Fousteri G, Jofra T, Di Fonte R, Battaglia M.

PLoS One. 2015 Jun 16;10(6):e0127631. doi: 10.1371/journal.pone.0127631. eCollection 2015.

18.

Lack of the protein tyrosine phosphatase PTPN22 strengthens transplant tolerance to pancreatic islets in mice.

Fousteri G, Jofra T, Di Fonte R, Gagliani N, Morsiani C, Stabilini A, Battaglia M.

Diabetologia. 2015 Jun;58(6):1319-28. doi: 10.1007/s00125-015-3540-9. Epub 2015 Mar 7.

PMID:
25748328
19.

PTPN22 controls virally-induced autoimmune diabetes by modulating cytotoxic T lymphocyte responses in an epitope-specific manner.

Fousteri G, Jofra T, Di Fonte R, Kuka M, Iannacone M, Battaglia M.

Clin Immunol. 2015 Feb;156(2):98-108. doi: 10.1016/j.clim.2014.12.002. Epub 2014 Dec 13.

PMID:
25513733
20.

BDC12-4.1 T-cell receptor transgenic insulin-specific CD4 T cells are resistant to in vitro differentiation into functional Foxp3+ T regulatory cells.

Sarikonda G, Fousteri G, Sachithanantham S, Miller JF, Dave A, Juntti T, Coppieters KT, von Herrath M.

PLoS One. 2014 Nov 13;9(11):e112242. doi: 10.1371/journal.pone.0112242. eCollection 2014.

21.

The protein tyrosine phosphatase PTPN22 controls forkhead box protein 3 T regulatory cell induction but is dispensable for T helper type 1 cell polarization.

Fousteri G, Jofra T, Debernardis I, Stanford SM, Laurenzi A, Bottini N, Battaglia M.

Clin Exp Immunol. 2014 Oct;178(1):178-89. doi: 10.1111/cei.12393.

22.

Regulatory T cells control diabetes without compromising acute anti-viral defense.

Jones CB, Pagni PP, Fousteri G, Sachithanantham S, Dave A, Rodriguez-Calvo T, Miller J, von Herrath M.

Clin Immunol. 2014 Aug;153(2):298-307. doi: 10.1016/j.clim.2014.05.006. Epub 2014 May 22.

23.

CD4⁺ T cells from IPEX patients convert into functional and stable regulatory T cells by FOXP3 gene transfer.

Passerini L, Rossi Mel E, Sartirana C, Fousteri G, Bondanza A, Naldini L, Roncarolo MG, Bacchetta R.

Sci Transl Med. 2013 Dec 11;5(215):215ra174. doi: 10.1126/scitranslmed.3007320.

24.

Roles of the protein tyrosine phosphatase PTPN22 in immunity and autoimmunity.

Fousteri G, Liossis SN, Battaglia M.

Clin Immunol. 2013 Dec;149(3):556-65. doi: 10.1016/j.clim.2013.10.006. Epub 2013 Oct 21. Review.

PMID:
24269925
25.

Enforced IL-10 expression confers type 1 regulatory T cell (Tr1) phenotype and function to human CD4(+) T cells.

Andolfi G, Fousteri G, Rossetti M, Magnani CF, Jofra T, Locafaro G, Bondanza A, Gregori S, Roncarolo MG.

Mol Ther. 2012 Sep;20(9):1778-90. doi: 10.1038/mt.2012.71. Epub 2012 Jun 12.

26.

Following the fate of one insulin-reactive CD4 T cell: conversion into Teffs and Tregs in the periphery controls diabetes in NOD mice.

Fousteri G, Jasinski J, Dave A, Nakayama M, Pagni P, Lambolez F, Juntti T, Sarikonda G, Cheng Y, Croft M, Cheroutre H, Eisenbarth G, von Herrath M.

Diabetes. 2012 May;61(5):1169-79. doi: 10.2337/db11-0671. Epub 2012 Mar 8.

27.

Antigen-specific prevention of type 1 diabetes in NOD mice is ameliorated by OX40 agonist treatment.

Bresson D, Fousteri G, Manenkova Y, Croft M, von Herrath M.

J Autoimmun. 2011 Dec;37(4):342-51. doi: 10.1016/j.jaut.2011.10.001. Epub 2011 Nov 6.

28.

Nasal cardiac myosin peptide treatment and OX40 blockade protect mice from acute and chronic virally-induced myocarditis.

Fousteri G, Dave A, Morin B, Omid S, Croft M, von Herrath MG.

J Autoimmun. 2011 May;36(3-4):210-20. doi: 10.1016/j.jaut.2011.01.006. Epub 2011 Feb 17.

29.

Increased memory conversion of naïve CD8 T cells activated during late phases of acute virus infection due to decreased cumulative antigen exposure.

Fousteri G, Dave A, Juedes A, Juntti T, Morin B, Togher L, Farber DL, von Herrath M.

PLoS One. 2011 Jan 6;6(1):e14502. doi: 10.1371/journal.pone.0014502.

30.

Virtual optimization of nasal insulin therapy predicts immunization frequency to be crucial for diabetes protection.

Fousteri G, Chan JR, Zheng Y, Whiting C, Dave A, Bresson D, Croft M, von Herrath M.

Diabetes. 2010 Dec;59(12):3148-58. doi: 10.2337/db10-0561. Epub 2010 Sep 23.

31.

Minimal effect of CD103 expression on the control of a chronic antiviral immune response.

Fousteri G, Dave A, Juntti T, Morin B, McClure M, Von Herrath M.

Viral Immunol. 2010 Jun;23(3):285-94. doi: 10.1089/vim.2009.0110.

32.

Subcutaneous insulin B:9-23/IFA immunisation induces Tregs that control late-stage prediabetes in NOD mice through IL-10 and IFNgamma.

Fousteri G, Dave A, Bot A, Juntti T, Omid S, von Herrath M.

Diabetologia. 2010 Sep;53(9):1958-70. doi: 10.1007/s00125-010-1777-x. Epub 2010 May 20.

33.

CD103 is dispensable for anti-viral immunity and autoimmunity in a mouse model of virally-induced autoimmune diabetes.

Fousteri G, Dave A, Juntti T, von Herrath M.

J Autoimmun. 2009 Feb;32(1):70-7. doi: 10.1016/j.jaut.2008.12.001. Epub 2009 Jan 21.

34.

First-trimester human fetal pancreas transplantation for type 1 diabetes treatment: an alternative approach for achieving long-term graft survival?

Fousteri G, von Herrath M.

Diabetes. 2008 Mar;57(3):525-6. doi: 10.2337/db07-1409. No abstract available.

35.

Stopping diabetes in its tracks: autologous non-myeloablative stem cell transplantation.

Fousteri G, Hayek A, von Herrath M.

Regen Med. 2007 Sep;2(5):845-51.

PMID:
17907936
36.

Rational development of antigen-specific therapies for type 1 diabetes.

Fousteri G, Bresson D, von Herrath M.

Adv Exp Med Biol. 2007;601:313-9. Review.

PMID:
17713020
37.

An essential role for TNF in modulating thresholds for survival, activation, and tolerance of CD8+ T cells.

Chatzidakis I, Fousteri G, Tsoukatou D, Kollias G, Mamalaki C.

J Immunol. 2007 Jun 1;178(11):6735-45.

38.

Mucosal exposure to antigen: cause or cure of type 1 diabetes?

Fousteri G, von Herrath M, Bresson D.

Curr Diab Rep. 2007 Apr;7(2):91-8. Review.

PMID:
17425912

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