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Items: 1 to 50 of 154

1.

ATP-Evoked Intracellular Ca2+ Responses in M-CSF Differentiated Human Monocyte-Derived Macrophage are Mediated by P2X4 and P2Y11 Receptor Activation.

Layhadi JA, Fountain SJ.

Int J Mol Sci. 2019 Oct 15;20(20). pii: E5113. doi: 10.3390/ijms20205113.

PMID:
31618941
Free PMC Article

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2.

Sex differences in serial pattern learning in mice.

Kundey SMA, Bajracharya A, Boettger-Tong H, Fountain SB, Rowan JD.

Behav Processes. 2019 Nov;168:103958. doi: 10.1016/j.beproc.2019.103958. Epub 2019 Sep 8.

PMID:
31509770

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3.

Adolescent exposure to fluoxetine impairs serial pattern learning in the serial multiple choice (SMC) task in adult rats.

Sharp JL, Miller-Cahill ME, Renaud SM, Kundey SMA, Kelley BM, Matoushek AW, Dyer KH, Jackman CC, Fountain SB, Rowan JD.

Neurobiol Learn Mem. 2019 Oct;164:107048. doi: 10.1016/j.nlm.2019.107048. Epub 2019 Jul 27.

PMID:
31362058

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4.

Inhibitors of DAG metabolism suppress CCR2 signalling in human monocytes.

Day P, Burrows L, Richards D, Fountain SJ.

Br J Pharmacol. 2019 Aug;176(15):2736-2749. doi: 10.1111/bph.14695. Epub 2019 Jun 17.

PMID:
31032885

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5.

Action of MK-7264 (gefapixant) at human P2X3 and P2X2/3 receptors and in vivo efficacy in models of sensitisation.

Richards D, Gever JR, Ford AP, Fountain SJ.

Br J Pharmacol. 2019 Jul;176(13):2279-2291. doi: 10.1111/bph.14677. Epub 2019 May 11.

PMID:
30927255

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6.

Constitutive P2Y2 receptor activity regulates basal lipolysis in human adipocytes.

Ali SB, Turner JJO, Fountain SJ.

J Cell Sci. 2018 Nov 19;131(22). pii: jcs221994. doi: 10.1242/jcs.221994.

PMID:
30333139
Free Article

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7.

P2Y2 and P2Y6 receptor activation elicits intracellular calcium responses in human adipose-derived mesenchymal stromal cells.

Ali S, Turner J, Fountain SJ.

Purinergic Signal. 2018 Dec;14(4):371-384. doi: 10.1007/s11302-018-9618-3. Epub 2018 Aug 7.

PMID:
30088129
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8.

Serial pattern retention in male and female rats.

Sharp JL, Miller-Cahill ME, Riccio DC, Fountain SB.

Neurobiol Learn Mem. 2018 Nov;155:578-582. doi: 10.1016/j.nlm.2018.05.018. Epub 2018 May 29.

PMID:
29857047

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9.

11th GCC Closed Forum: cumulative stability; matrix stability; immunogenicity assays; laboratory manuals; biosimilars; chiral methods; hybrid LBA/LCMS assays; fit-for-purpose validation; China Food and Drug Administration bioanalytical method validation.

Islam R, Briscoe C, Bower J, Cape S, Arnold M, Hayes R, Warren M, Karnik S, Stouffer B, Xiao YQ, van der Strate B, Sikkema D, Fang X, Tudoroniu A, Tayyem R, Brant A, Spriggs F, Barry C, Khan M, Keyhani A, Zimmer J, Caturla MC, Couerbe P, Khadang A, Bourdage J, Datin J, Zemo J, Hughes N, Fatmi S, Sheldon C, Fountain S, Satterwhite C, Colletti K, Vija J, Yu M, Stamatopoulos J, Lin J, Wilfahrt J, Dinan A, Ohorodnik S, Hulse J, Patel V, Garofolo W, Savoie N, Brown M, Papac D, Buonarati M, Hristopoulos G, Beaver C, Boudreau N, Williard C, Liu Y, Ray G, Warrino D, Xu A, Green R, Hayward-Sewell J, Marcelletti J, Sanchez C, Kennedy M, Charles JS, Bouhajib M, Nehls C, Tabler E, Tu J, Joyce P, Iordachescu A, DuBey I, Lindsay J, Yamashita J, Wells E.

Bioanalysis. 2018 Apr 1;10(7):433-444. doi: 10.4155/bio-2018-0014. Epub 2018 Apr 27.

PMID:
29701066
Free Article

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10.

P2Y12 receptor modulation of ADP-evoked intracellular Ca2+ signalling in THP-1 human monocytic cells.

Micklewright JJ, Layhadi JA, Fountain SJ.

Br J Pharmacol. 2018 Jun;175(12):2483-2491. doi: 10.1111/bph.14218. Epub 2018 Apr 29.

PMID:
29574692
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11.

ATP Evokes Ca2+ Responses and CXCL5 Secretion via P2X4 Receptor Activation in Human Monocyte-Derived Macrophages.

Layhadi JA, Turner J, Crossman D, Fountain SJ.

J Immunol. 2018 Feb 1;200(3):1159-1168. doi: 10.4049/jimmunol.1700965. Epub 2017 Dec 18.

PMID:
29255078
Free PMC Article

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12.

P2X4 Receptor-Dependent Ca2+ Influx in Model Human Monocytes and Macrophages.

Layhadi JA, Fountain SJ.

Int J Mol Sci. 2017 Oct 27;18(11). pii: E2261. doi: 10.3390/ijms18112261.

PMID:
29077063
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13.

P2X4 Receptor Function in the Nervous System and Current Breakthroughs in Pharmacology.

Stokes L, Layhadi JA, Bibic L, Dhuna K, Fountain SJ.

Front Pharmacol. 2017 May 23;8:291. doi: 10.3389/fphar.2017.00291. eCollection 2017. Review.

PMID:
28588493
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14.

Influence of ER leak on resting cytoplasmic Ca2+ and receptor-mediated Ca2+ signalling in human macrophage.

Layhadi JA, Fountain SJ.

Biochem Biophys Res Commun. 2017 Jun 3;487(3):633-639. doi: 10.1016/j.bbrc.2017.04.106. Epub 2017 Apr 20.

PMID:
28435065

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15.

Serial pattern learning in pigeons: Rule-based or associative?

Garlick D, Fountain SB, Blaisdell AP.

J Exp Psychol Anim Learn Cogn. 2017 Jan;43(1):30-47. doi: 10.1037/xan0000109. Epub 2016 Sep 5.

PMID:
27598058
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16.

Transgenerational effects of adolescent nicotine exposure in rats: Evidence for cognitive deficits in adult female offspring.

Renaud SM, Fountain SB.

Neurotoxicol Teratol. 2016 Jul-Aug;56:47-54. doi: 10.1016/j.ntt.2016.06.002. Epub 2016 Jun 7.

PMID:
27286749
Free PMC Article

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17.

Strategy breakdown following muscarinic blockade in rats.

Chenoweth AM, Fountain SB.

Neurobiol Learn Mem. 2016 May;131:83-6. doi: 10.1016/j.nlm.2016.03.005. Epub 2016 Mar 11.

PMID:
26976093

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18.

Concurrent cognitive processes in rat serial pattern learning: II. Discrimination learning, rule learning, chunk length, and multiple-item memories.

Muller MD, Fountain SB.

J Exp Anal Behav. 2016 Jan;105(1):155-75. doi: 10.1002/jeab.186.

PMID:
26781054

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19.

Additional factors to take into account when diagnosing miscarriage.

Fountain SA, Dipper M, Smith H.

BMJ. 2015 Nov 4;351:h5851. doi: 10.1136/bmj.h5851. No abstract available.

PMID:
26537252

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20.

Monitoring Healing Progression and Characterizing the Mechanical Environment in Preclinical Models for Bone Tissue Engineering.

Fountain S, Windolf M, Henkel J, Tavakoli A, Schuetz MA, Hutmacher DW, Epari DR.

Tissue Eng Part B Rev. 2016 Feb;22(1):47-57. doi: 10.1089/ten.TEB.2015.0123. Epub 2015 Dec 15.

PMID:
26507933

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21.

Bladder squamous cell carcinoma in pregnancy.

Alleemudder DI, Alleemudder AI, Harry D, Fountain S.

J Obstet Gynaecol. 2016;36(3):388-9. doi: 10.3109/01443615.2015.1085844. Epub 2015 Oct 14. No abstract available.

PMID:
26467844

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22.

Adolescent exposure to methylphenidate impairs serial pattern learning in the serial multiple choice (SMC) task in adult rats.

Rowan JD, McCarty MK, Kundey SM, Osburn CD, Renaud SM, Kelley BM, Matoushek AW, Fountain SB.

Neurotoxicol Teratol. 2015 Sep-Oct;51:21-6. doi: 10.1016/j.ntt.2015.07.007. Epub 2015 Jul 28.

PMID:
26225921

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23.

Evidence for Extracellular ATP as a Stress Signal in a Single-Celled Organism.

Sivaramakrishnan V, Fountain SJ.

Eukaryot Cell. 2015 Aug;14(8):775-82. doi: 10.1128/EC.00066-15. Epub 2015 Jun 5.

PMID:
26048010
Free PMC Article

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24.

Central muscarinic cholinergic involvement in serial pattern learning: Atropine impairs acquisition and retention in a serial multiple choice (SMC) task in rats.

Chenoweth AM, Fountain SB.

Neurobiol Learn Mem. 2015 Sep;123:18-27. doi: 10.1016/j.nlm.2015.04.003. Epub 2015 Apr 23.

PMID:
25914128

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25.

Paradoxical effects of injection stress and nicotine exposure experienced during adolescence on learning in a serial multiple choice (SMC) task in adult female rats.

Renaud SM, Pickens LR, Fountain SB.

Neurotoxicol Teratol. 2015 Mar-Apr;48:40-8. doi: 10.1016/j.ntt.2014.12.003. Epub 2014 Dec 17.

PMID:
25527003
Free PMC Article

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26.

P2Y₆ receptor inhibition perturbs CCL2-evoked signalling in human monocytic and peripheral blood mononuclear cells.

Campwala H, Sexton DW, Crossman DC, Fountain SJ.

J Cell Sci. 2014 Nov 15;127(Pt 22):4964-73. doi: 10.1242/jcs.159012. Epub 2014 Sep 30.

PMID:
25271060
Free PMC Article

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27.

A comparison of the long-term consequences of vaginal delivery versus caesarean section of the prevalence, severity and bothersomeness of urinary incontinence subtypes: a national cohort study in primiparous women.

Fountain S, Alleemudder D.

BJOG. 2014 Aug;121(9):1175-6. doi: 10.1111/1471-0528.12672. No abstract available.

PMID:
25047491
Free Article

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28.

The 'blended' bioanalytical laboratory: the marriage of antibody- and instrument-based methods and expertise.

Fountain ST.

Bioanalysis. 2014 Mar;6(6):717-9. doi: 10.4155/bio.14.23. No abstract available.

PMID:
24702104
Free Article

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29.

Primitive ATP-activated P2X receptors: discovery, function and pharmacology.

Fountain SJ.

Front Cell Neurosci. 2013 Dec 6;7:247. doi: 10.3389/fncel.2013.00247. Review.

PMID:
24367292
Free PMC Article

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30.

Relationships between depression, anxiety, and pain in a group of university music students.

Wristen BW, Fountain SE.

Med Probl Perform Art. 2013 Sep;28(3):152-8.

PMID:
24013287

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31.

Multiple births following in vitro fertilization treatment: redefining success.

Umranikar A, Parmar D, Davies S, Fountain S.

Eur J Obstet Gynecol Reprod Biol. 2013 Oct;170(2):299-304. doi: 10.1016/j.ejogrb.2013.06.031. Epub 2013 Jul 25. Review.

PMID:
23891391

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32.

Central cholinergic involvement in sequential behavior: impairments of performance by atropine in a serial multiple choice task for rats.

Fountain SB, Rowan JD, Wollan MO.

Neurobiol Learn Mem. 2013 Nov;106:118-26. doi: 10.1016/j.nlm.2013.07.009. Epub 2013 Jul 18.

PMID:
23871743
Free PMC Article

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33.

Constitutive and agonist stimulated ATP secretion in leukocytes.

Campwala H, Fountain SJ.

Commun Integr Biol. 2013 May 1;6(3):e23631. doi: 10.4161/cib.23631. Epub 2013 May 13.

PMID:
23713132
Free PMC Article

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34.

Sex differences in adult cognitive deficits after adolescent nicotine exposure in rats.

Pickens LR, Rowan JD, Bevins RA, Fountain SB.

Neurotoxicol Teratol. 2013 Jul-Aug;38:72-8. doi: 10.1016/j.ntt.2013.05.001. Epub 2013 May 12.

PMID:
23673345
Free PMC Article

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35.

Acute Transverse Myelitis Associated with Buserelin Use during IVF.

Alleemudder DI, Sadek K, Fountain S, Davies S.

Case Rep Obstet Gynecol. 2013;2013:386765. doi: 10.1155/2013/386765. Epub 2013 Mar 28.

PMID:
23607013
Free PMC Article

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36.

Intracellular P2X receptors as novel calcium release channels and modulators of osmoregulation in Dictyostelium: a comparison of two common laboratory strains.

Sivaramakrishnan V, Fountain SJ.

Channels (Austin). 2013 Jan 1;7(1):43-6. doi: 10.4161/chan.22737. Epub 2012 Dec 6.

PMID:
23221467
Free PMC Article

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37.

Tissue bioanalysis of biotherapeutics and drug targets to support PK/PD.

Neubert H, Fountain S, King L, Clark T, Weng Y, O'Hara DM, Li W, Leung S, Ray C, Palandra J, Ocaña MF, Chen J, Ji C, Wang M, Long K, Gorovits B, Fluhler E.

Bioanalysis. 2012 Nov;4(21):2589-604. doi: 10.4155/bio.12.234. Review.

PMID:
23173794

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38.

Constitutive lysosome exocytosis releases ATP and engages P2Y receptors in human monocytes.

Sivaramakrishnan V, Bidula S, Campwala H, Katikaneni D, Fountain SJ.

J Cell Sci. 2012 Oct 1;125(Pt 19):4567-75. doi: 10.1242/jcs.107318. Epub 2012 Jul 5.

PMID:
22767503
Free Article

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39.

A mechanism of intracellular P2X receptor activation.

Sivaramakrishnan V, Fountain SJ.

J Biol Chem. 2012 Aug 17;287(34):28315-26. doi: 10.1074/jbc.M112.372565. Epub 2012 Jun 26.

PMID:
22736763
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40.

Fluvastatin suppresses native and recombinant human P2X4 receptor function.

Li J, Fountain SJ.

Purinergic Signal. 2012 Jun;8(2):311-6. doi: 10.1007/s11302-011-9289-9. Epub 2012 Jan 6.

PMID:
22222818
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41.

How current understanding of clearance mechanisms and pharmacodynamics of therapeutic proteins can be applied for evaluation of their drug-drug interaction potential.

Kraynov E, Martin SW, Hurst S, Fahmi OA, Dowty M, Cronenberger C, Loi CM, Kuang B, Fields O, Fountain S, Awwad M, Wang D.

Drug Metab Dispos. 2011 Oct;39(10):1779-83. doi: 10.1124/dmd.111.040808. Epub 2011 Jul 18. Review.

PMID:
21768274

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42.

Irrelevant relations and the active search for pattern structure in rat serial pattern learning.

Kundey SM, Fountain SB.

Anim Cogn. 2011 May;14(3):359-68. doi: 10.1007/s10071-010-0370-5. Epub 2011 Jan 19.

PMID:
21246231
Free PMC Article

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43.

The validation of a simple LC/MS/MS method for determining the level of mevalonic acid in human plasma.

Kindt E, Szekely-Klepser G, Fountain ST.

Biomed Chromatogr. 2011 Mar;25(3):323-9. doi: 10.1002/bmc.1449.

PMID:
21110384

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44.

Concurrent Cognitive Processes in Rat Serial Pattern Learning: Item Memory, Serial Position, and Pattern Structure.

Muller MD, Fountain SB.

Learn Motiv. 2010 Nov;41(4):252-272.

PMID:
22969166
Free PMC Article

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45.

Blocking in rat serial pattern learning.

Kundey SM, Fountain SB.

J Exp Psychol Anim Behav Process. 2010 Apr;36(2):307-12. doi: 10.1037/a0016523.

PMID:
20384409

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46.

Neurotransmitter receptor homologues of Dictyostelium discoideum.

Fountain SJ.

J Mol Neurosci. 2010 Jun;41(2):263-6. doi: 10.1007/s12031-009-9298-0. Epub 2009 Oct 13. Review.

PMID:
19823779

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47.

Diethylation labeling combined with UPLC/MS/MS for simultaneous determination of a panel of monoamine neurotransmitters in rat prefrontal cortex microdialysates.

Ji C, Li W, Ren XD, El-Kattan AF, Kozak R, Fountain S, Lepsy C.

Anal Chem. 2008 Dec 1;80(23):9195-203. doi: 10.1021/ac801339z.

PMID:
19551941

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48.

Medical errors in orthopaedics. Results of an AAOS member survey.

Wong DA, Herndon JH, Canale ST, Brooks RL, Hunt TR, Epps HR, Fountain SS, Albanese SA, Johanson NA.

J Bone Joint Surg Am. 2009 Mar 1;91(3):547-57. doi: 10.2106/JBJS.G.01439.

PMID:
19255214

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49.

An evolutionary history of P2X receptors.

Fountain SJ, Burnstock G.

Purinergic Signal. 2009 Sep;5(3):269-72. doi: 10.1007/s11302-008-9127-x. Epub 2008 Nov 18.

PMID:
19015952
Free PMC Article

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50.

Quantitative rt-PCR methods for investigation of low copy potassium channel gene expression in native murine arteries.

Cheong A, Fountain SJ, Beech DJ.

Methods Mol Biol. 2008;491:19-33. doi: 10.1007/978-1-59745-526-8_2.

PMID:
18998081

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