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Items: 38


The molecular biology of fruity and floral aromas in beer and other alcoholic beverages.

Holt S, Miks MH, de Carvalho BT, Foulquié-Moreno MR, Thevelein JM.

FEMS Microbiol Rev. 2019 May 1;43(3):193-222. doi: 10.1093/femsre/fuy041.


Polygenic Analysis in Absence of Major Effector ATF1 Unveils Novel Components in Yeast Flavor Ester Biosynthesis.

Holt S, Trindade de Carvalho B, Foulquié-Moreno MR, Thevelein JM.

MBio. 2018 Aug 28;9(4). pii: e01279-18. doi: 10.1128/mBio.01279-18.


Identification of Novel Alleles Conferring Superior Production of Rose Flavor Phenylethyl Acetate Using Polygenic Analysis in Yeast.

Trindade de Carvalho B, Holt S, Souffriau B, Lopes Brandão R, Foulquié-Moreno MR, Thevelein JM.

MBio. 2017 Nov 7;8(6). pii: e01173-17. doi: 10.1128/mBio.01173-17.


Strain Breeding Enhanced Heterologous Cellobiohydrolase Secretion by Saccharomyces cerevisiae in a Protein Specific Manner.

Kroukamp H, den Haan R, la Grange DC, Sibanda N, Foulquié-Moreno MR, Thevelein JM, van Zyl WH.

Biotechnol J. 2017 Oct;12(10). doi: 10.1002/biot.201700346. Epub 2017 Sep 15.


Fed-batch production of green coconut hydrolysates for high-gravity second-generation bioethanol fermentation with cellulosic yeast.

Soares J, Demeke MM, Van de Velde M, Foulquié-Moreno MR, Kerstens D, Sels BF, Verplaetse A, Fernandes AAR, Thevelein JM, Fernandes PMB.

Bioresour Technol. 2017 Nov;244(Pt 1):234-242. doi: 10.1016/j.biortech.2017.07.140. Epub 2017 Jul 27.


Engineering tolerance to industrially relevant stress factors in yeast cell factories.

Deparis Q, Claes A, Foulquié-Moreno MR, Thevelein JM.

FEMS Yeast Res. 2017 Jun 1;17(4). doi: 10.1093/femsyr/fox036. Review.


Genomic saturation mutagenesis and polygenic analysis identify novel yeast genes affecting ethyl acetate production, a non-selectable polygenic trait.

Abt TD, Souffriau B, Foulquié-Moreno MR, Duitama J, Thevelein JM.

Microb Cell. 2016 Mar 18;3(4):159-175. doi: 10.15698/mic2016.04.491.


Major sulfonate transporter Soa1 in Saccharomyces cerevisiae and considerable substrate diversity in its fungal family.

Holt S, Kankipati H, De Graeve S, Van Zeebroeck G, Foulquié-Moreno MR, Lindgreen S, Thevelein JM.

Nat Commun. 2017 Feb 6;8:14247. doi: 10.1038/ncomms14247.


Green coconut mesocarp pretreated by an alkaline process as raw material for bioethanol production.

Soares J, Demeke MM, Foulquié-Moreno MR, Van de Velde M, Verplaetse A, Fernandes AA, Thevelein JM, Fernandes PM.

Bioresour Technol. 2016 Sep;216:744-53. doi: 10.1016/j.biortech.2016.05.105. Epub 2016 May 31.


Polygenic analysis and targeted improvement of the complex trait of high acetic acid tolerance in the yeast Saccharomyces cerevisiae.

Meijnen JP, Randazzo P, Foulquié-Moreno MR, van den Brink J, Vandecruys P, Stojiljkovic M, Dumortier F, Zalar P, Boekhout T, Gunde-Cimerman N, Kokošar J, Štajdohar M, Curk T, Petrovič U, Thevelein JM.

Biotechnol Biofuels. 2016 Jan 6;9:5. doi: 10.1186/s13068-015-0421-x. eCollection 2016.


Comparative fluxome and metabolome analysis for overproduction of succinate in Escherichia coli.

Taymaz-Nikerel H, De Mey M, Baart GJ, Maertens J, Foulquié-Moreno MR, Charlier D, Heijnen JJ, van Gulik WM.

Biotechnol Bioeng. 2016 Apr;113(4):817-29. doi: 10.1002/bit.25850. Epub 2015 Oct 18.


Looking beyond Saccharomyces: the potential of non-conventional yeast species for desirable traits in bioethanol fermentation.

Radecka D, Mukherjee V, Mateo RQ, Stojiljkovic M, Foulquié-Moreno MR, Thevelein JM.

FEMS Yeast Res. 2015 Sep;15(6). pii: fov053. doi: 10.1093/femsyr/fov053. Epub 2015 Jun 29. Review.


Auxotrophic Mutations Reduce Tolerance of Saccharomyces cerevisiae to Very High Levels of Ethanol Stress.

Swinnen S, Goovaerts A, Schaerlaekens K, Dumortier F, Verdyck P, Souvereyns K, Van Zeebroeck G, Foulquié-Moreno MR, Thevelein JM.

Eukaryot Cell. 2015 Sep;14(9):884-97. doi: 10.1128/EC.00053-15. Epub 2015 Jun 26.


Rapid evolution of recombinant Saccharomyces cerevisiae for Xylose fermentation through formation of extra-chromosomal circular DNA.

Demeke MM, Foulquié-Moreno MR, Dumortier F, Thevelein JM.

PLoS Genet. 2015 Mar 4;11(3):e1005010. doi: 10.1371/journal.pgen.1005010. eCollection 2015 Mar.


Re-assessment of YAP1 and MCR1 contributions to inhibitor tolerance in robust engineered Saccharomyces cerevisiae fermenting undetoxified lignocellulosic hydrolysate.

Wallace-Salinas V, Signori L, Li YY, Ask M, Bettiga M, Porro D, Thevelein JM, Branduardi P, Foulquié-Moreno MR, Gorwa-Grauslund M.

AMB Express. 2014 Jul 22;4:56. doi: 10.1186/s13568-014-0056-5. eCollection 2014.


QTL mapping by pooled-segregant whole-genome sequencing in yeast.

Pais TM, Foulquié-Moreno MR, Thevelein JM.

Methods Mol Biol. 2014;1152:251-66. doi: 10.1007/978-1-4939-0563-8_15.


Improved linkage analysis of Quantitative Trait Loci using bulk segregants unveils a novel determinant of high ethanol tolerance in yeast.

Duitama J, Sánchez-Rodríguez A, Goovaerts A, Pulido-Tamayo S, Hubmann G, Foulquié-Moreno MR, Thevelein JM, Verstrepen KJ, Marchal K.

BMC Genomics. 2014 Mar 19;15:207. doi: 10.1186/1471-2164-15-207.


An integrated framework for discovery and genotyping of genomic variants from high-throughput sequencing experiments.

Duitama J, Quintero JC, Cruz DF, Quintero C, Hubmann G, Foulquié-Moreno MR, Verstrepen KJ, Thevelein JM, Tohme J.

Nucleic Acids Res. 2014 Apr;42(6):e44. doi: 10.1093/nar/gkt1381. Epub 2014 Jan 11.


Combining inhibitor tolerance and D-xylose fermentation in industrial Saccharomyces cerevisiae for efficient lignocellulose-based bioethanol production.

Demeke MM, Dumortier F, Li Y, Broeckx T, Foulquié-Moreno MR, Thevelein JM.

Biotechnol Biofuels. 2013 Aug 26;6(1):120. doi: 10.1186/1754-6834-6-120.


QTL analysis of high thermotolerance with superior and downgraded parental yeast strains reveals new minor QTLs and converges on novel causative alleles involved in RNA processing.

Yang Y, Foulquié-Moreno MR, Clement L, Erdei E, Tanghe A, Schaerlaekens K, Dumortier F, Thevelein JM.

PLoS Genet. 2013;9(8):e1003693. doi: 10.1371/journal.pgen.1003693. Epub 2013 Aug 15.


Development of a D-xylose fermenting and inhibitor tolerant industrial Saccharomyces cerevisiae strain with high performance in lignocellulose hydrolysates using metabolic and evolutionary engineering.

Demeke MM, Dietz H, Li Y, Foulquié-Moreno MR, Mutturi S, Deprez S, Den Abt T, Bonini BM, Liden G, Dumortier F, Verplaetse A, Boles E, Thevelein JM.

Biotechnol Biofuels. 2013 Jun 21;6(1):89. doi: 10.1186/1754-6834-6-89.


Identification of multiple interacting alleles conferring low glycerol and high ethanol yield in Saccharomyces cerevisiae ethanolic fermentation.

Hubmann G, Mathé L, Foulquié-Moreno MR, Duitama J, Nevoigt E, Thevelein JM.

Biotechnol Biofuels. 2013 Jun 11;6(1):87. doi: 10.1186/1754-6834-6-87.


Comparative polygenic analysis of maximal ethanol accumulation capacity and tolerance to high ethanol levels of cell proliferation in yeast.

Pais TM, Foulquié-Moreno MR, Hubmann G, Duitama J, Swinnen S, Goovaerts A, Yang Y, Dumortier F, Thevelein JM.

PLoS Genet. 2013 Jun;9(6):e1003548. doi: 10.1371/journal.pgen.1003548. Epub 2013 Jun 6.


Metabolic engineering for high yielding L(-)-carnitine production in Escherichia coli.

Arense P, Bernal V, Charlier D, Iborra JL, Foulquié-Moreno MR, Cánovas M.

Microb Cell Fact. 2013 May 29;12:56. doi: 10.1186/1475-2859-12-56.


Quantitative trait analysis of yeast biodiversity yields novel gene tools for metabolic engineering.

Hubmann G, Foulquié-Moreno MR, Nevoigt E, Duitama J, Meurens N, Pais TM, Mathé L, Saerens S, Nguyen HT, Swinnen S, Verstrepen KJ, Concilio L, de Troostembergh JC, Thevelein JM.

Metab Eng. 2013 May;17:68-81. doi: 10.1016/j.ymben.2013.02.006. Epub 2013 Mar 18.


Simultaneous mapping of multiple gene loci with pooled segregants.

Claesen J, Clement L, Shkedy Z, Foulquié-Moreno MR, Burzykowski T.

PLoS One. 2013;8(2):e55133. doi: 10.1371/journal.pone.0055133. Epub 2013 Feb 18.


Identification of novel causative genes determining the complex trait of high ethanol tolerance in yeast using pooled-segregant whole-genome sequence analysis.

Swinnen S, Schaerlaekens K, Pais T, Claesen J, Hubmann G, Yang Y, Demeke M, Foulquié-Moreno MR, Goovaerts A, Souvereyns K, Clement L, Dumortier F, Thevelein JM.

Genome Res. 2012 May;22(5):975-84. doi: 10.1101/gr.131698.111. Epub 2012 Mar 7.


Effect of iclR and arcA knockouts on biomass formation and metabolic fluxes in Escherichia coli K12 and its implications on understanding the metabolism of Escherichia coli BL21 (DE3).

Waegeman H, Beauprez J, Moens H, Maertens J, De Mey M, Foulquié-Moreno MR, Heijnen JJ, Charlier D, Soetaert W.

BMC Microbiol. 2011 Apr 11;11:70. doi: 10.1186/1471-2180-11-70.


Validation study of 24 deepwell microtiterplates to screen libraries of strains in metabolic engineering.

Waegeman H, Beauprez J, Maertens J, De Mey M, Demolder L, Foulquié-Moreno MR, Boon N, Charlier D, Soetaert W.

J Biosci Bioeng. 2010 Dec;110(6):646-52. doi: 10.1016/j.jbiosc.2010.07.008. Epub 2010 Aug 8.


Transient metabolic modeling of Escherichia coli MG1655 and MG1655 DeltaackA-pta, DeltapoxB Deltapppc ppc-p37 for recombinant beta-galactosidase production.

De Mey M, Lequeux GJ, Beauprez JJ, Maertens J, Waegeman HJ, Van Bogaert IN, Foulquié-Moreno MR, Charlier D, Soetaert WK, Vanrolleghem PA, Vandamme EJ.

J Ind Microbiol Biotechnol. 2010 Aug;37(8):793-803. doi: 10.1007/s10295-010-0724-7. Epub 2010 May 4.


Promoter knock-in: a novel rational method for the fine tuning of genes.

De Mey M, Maertens J, Boogmans S, Soetaert WK, Vandamme EJ, Cunin R, Foulquié-Moreno MR.

BMC Biotechnol. 2010 Mar 24;10:26. doi: 10.1186/1472-6750-10-26.


Diversity of heteropolysaccharide-producing lactic acid bacterium strains and their biopolymers.

Mozzi F, Vaningelgem F, Hébert EM, Van der Meulen R, Foulquié Moreno MR, Font de Valdez G, De Vuyst L.

Appl Environ Microbiol. 2006 Jun;72(6):4431-5.


The role and application of enterococci in food and health.

Foulquié Moreno MR, Sarantinopoulos P, Tsakalidou E, De Vuyst L.

Int J Food Microbiol. 2006 Jan 15;106(1):1-24. Epub 2005 Oct 10. Review.


Enterococcus faecium RZS C5, an interesting bacteriocin producer to be used as a co-culture in food fermentation.

Leroy F, Foulquié Moreno MR, De Vuyst L.

Int J Food Microbiol. 2003 Dec 1;88(2-3):235-40. Review.


Screening for enterocins and detection of hemolysin and vancomycin resistance in enterococci of different origins.

De Vuyst L, Foulquié Moreno MR, Revets H.

Int J Food Microbiol. 2003 Aug 1;84(3):299-318.


Isolation and biochemical characterisation of enterocins produced by enterococci from different sources.

Foulquié Moreno MR, Callewaert R, Devreese B, Van Beeumen J, De Vuyst L.

J Appl Microbiol. 2003;94(2):214-29.


Applicability of a bacteriocin-producing Enterococcus faecium as a co-culture in Cheddar cheese manufacture.

Foulquié Moreno MR, Rea MC, Cogan TM, De Vuyst L.

Int J Food Microbiol. 2003 Feb 25;81(1):73-84.


Intraspecies genomic groups in Enterococcus faecium and their correlation with origin and pathogenicity.

Vancanneyt M, Lombardi A, Andrighetto C, Knijff E, Torriani S, Björkroth KJ, Franz CM, Foulquié Moreno MR, Revets H, De Vuyst L, Swings J, Kersters K, Dellaglio F, Holzapfel WH.

Appl Environ Microbiol. 2002 Mar;68(3):1381-91.

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