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Items: 39


Effect of Polymer Demixed Nanotopographies on Bacterial Adhesion and Biofilm Formation.

Fleming G, Aveyard J, Fothergill JL, McBride F, Raval R, D'Sa RA.

Polymers (Basel). 2019 Nov 21;11(12). pii: E1921. doi: 10.3390/polym11121921.


Reservoirs of resistance: polymyxin resistance in veterinary-associated companion animal isolates of Pseudomonas aeruginosa.

Scott A, Pottenger S, Timofte D, Moore M, Wright L, Kukavica-Ibrulj I, Jeukens J, Levesque RC, Freschi L, Pinchbeck GL, Schmidt VM, McEwan N, Radford AD, Fothergill JL.

Vet Rec. 2019 Aug 17;185(7):206. doi: 10.1136/vr.105075. Epub 2019 Jun 25.


Evolutionary trade-offs associated with loss of PmrB function in host-adapted Pseudomonas aeruginosa.

Bricio-Moreno L, Sheridan VH, Goodhead I, Armstrong S, Wong JKL, Waters EM, Sarsby J, Panagiotou S, Dunn J, Chakraborty A, Fang Y, Griswold KE, Winstanley C, Fothergill JL, Kadioglu A, Neill DR.

Nat Commun. 2018 Jul 6;9(1):2635. doi: 10.1038/s41467-018-04996-x.


Genomic characterisation of an international Pseudomonas aeruginosa reference panel indicates that the two major groups draw upon distinct mobile gene pools.

Freschi L, Bertelli C, Jeukens J, Moore MP, Kukavica-Ibrulj I, Emond-Rheault JG, Hamel J, Fothergill JL, Tucker NP, McClean S, Klockgether J, de Soyza A, Brinkman FSL, Levesque RC, Winstanley C.

FEMS Microbiol Lett. 2018 Jul 1;365(14). doi: 10.1093/femsle/fny120.


Transmission and lineage displacement drive rapid population genomic flux in cystic fibrosis airway infections of a Pseudomonas aeruginosa epidemic strain.

Williams D, Fothergill JL, Evans B, Caples J, Haldenby S, Walshaw MJ, Brockhurst MA, Winstanley C, Paterson S.

Microb Genom. 2018 Mar;4(3). doi: 10.1099/mgen.0.000167. Epub 2018 Mar 16.


Nitric Oxide Releasing Polymeric Coatings for the Prevention of Biofilm Formation.

Fleming G, Aveyard J, Fothergill JL, McBride F, Raval R, D'Sa RA.

Polymers (Basel). 2017 Nov 11;9(11). pii: E601. doi: 10.3390/polym9110601.


The role of multispecies social interactions in shaping Pseudomonas aeruginosa pathogenicity in the cystic fibrosis lung.

O'Brien S, Fothergill JL.

FEMS Microbiol Lett. 2017 Aug 15;364(15). doi: 10.1093/femsle/fnx128. Review.


The contribution of Pseudomonas aeruginosa virulence factors and host factors in the establishment of urinary tract infections.

Newman JW, Floyd RV, Fothergill JL.

FEMS Microbiol Lett. 2017 Aug 15;364(15). doi: 10.1093/femsle/fnx124. Review.


Pseudomonas aeruginosa adaptation and diversification in the non-cystic fibrosis bronchiectasis lung.

Hilliam Y, Moore MP, Lamont IL, Bilton D, Haworth CS, Foweraker J, Walshaw MJ, Williams D, Fothergill JL, De Soyza A, Winstanley C.

Eur Respir J. 2017 Apr 26;49(4). pii: 1602108. doi: 10.1183/13993003.02108-2016. Print 2017 Apr.


High virulence sub-populations in Pseudomonas aeruginosa long-term cystic fibrosis airway infections.

O'Brien S, Williams D, Fothergill JL, Paterson S, Winstanley C, Brockhurst MA.

BMC Microbiol. 2017 Feb 3;17(1):30. doi: 10.1186/s12866-017-0941-6.


Temperate phages both mediate and drive adaptive evolution in pathogen biofilms.

Davies EV, James CE, Williams D, O'Brien S, Fothergill JL, Haldenby S, Paterson S, Winstanley C, Brockhurst MA.

Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8266-71. doi: 10.1073/pnas.1520056113. Epub 2016 Jul 5.


The role of temperate bacteriophages in bacterial infection.

Davies EV, Winstanley C, Fothergill JL, James CE.

FEMS Microbiol Lett. 2016 Mar;363(5):fnw015. doi: 10.1093/femsle/fnw015. Epub 2016 Jan 28. Review.


Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium.

Freschi L, Jeukens J, Kukavica-Ibrulj I, Boyle B, Dupont MJ, Laroche J, Larose S, Maaroufi H, Fothergill JL, Moore M, Winsor GL, Aaron SD, Barbeau J, Bell SC, Burns JL, Camara M, Cantin A, Charette SJ, Dewar K, Déziel É, Grimwood K, Hancock RE, Harrison JJ, Heeb S, Jelsbak L, Jia B, Kenna DT, Kidd TJ, Klockgether J, Lam JS, Lamont IL, Lewenza S, Loman N, Malouin F, Manos J, McArthur AG, McKeown J, Milot J, Naghra H, Nguyen D, Pereira SK, Perron GG, Pirnay JP, Rainey PB, Rousseau S, Santos PM, Stephenson A, Taylor V, Turton JF, Waglechner N, Williams P, Thrane SW, Wright GD, Brinkman FS, Tucker NP, Tümmler B, Winstanley C, Levesque RC.

Front Microbiol. 2015 Sep 29;6:1036. doi: 10.3389/fmicb.2015.01036. eCollection 2015.


Genes Required for Free Phage Production are Essential for Pseudomonas aeruginosa Chronic Lung Infections.

Lemieux AA, Jeukens J, Kukavica-Ibrulj I, Fothergill JL, Boyle B, Laroche J, Tucker NP, Winstanley C, Levesque RC.

J Infect Dis. 2016 Feb 1;213(3):395-402. doi: 10.1093/infdis/jiv415. Epub 2015 Aug 12.


Lytic activity by temperate phages of Pseudomonas aeruginosa in long-term cystic fibrosis chronic lung infections.

James CE, Davies EV, Fothergill JL, Walshaw MJ, Beale CM, Brockhurst MA, Winstanley C.

ISME J. 2015 Jun;9(6):1391-8. doi: 10.1038/ismej.2014.223. Epub 2014 Dec 2.


Turnover of strains and intraclonal variation amongst Pseudomonas aeruginosa isolates from paediatric CF patients.

Hall AJ, Fothergill JL, McNamara PS, Southern KW, Winstanley C.

Diagn Microbiol Infect Dis. 2014 Dec;80(4):324-6. doi: 10.1016/j.diagmicrobio.2014.09.007. Epub 2014 Sep 16.


Pseudomonas aeruginosa adaptation in the nasopharyngeal reservoir leads to migration and persistence in the lungs.

Fothergill JL, Neill DR, Loman N, Winstanley C, Kadioglu A.

Nat Commun. 2014 Sep 2;5:4780. doi: 10.1038/ncomms5780.


The B lymphocyte differentiation factor (BAFF) is expressed in the airways of children with CF and in lungs of mice infected with Pseudomonas aeruginosa.

Neill DR, Saint GL, Bricio-Moreno L, Fothergill JL, Southern KW, Winstanley C, Christmas SE, Slupsky JR, McNamara PS, Kadioglu A, Flanagan BF.

PLoS One. 2014 May 21;9(5):e95892. doi: 10.1371/journal.pone.0095892. eCollection 2014.


Comparative genomics of isolates of a Pseudomonas aeruginosa epidemic strain associated with chronic lung infections of cystic fibrosis patients.

Jeukens J, Boyle B, Kukavica-Ibrulj I, Ouellet MM, Aaron SD, Charette SJ, Fothergill JL, Tucker NP, Winstanley C, Levesque RC.

PLoS One. 2014 Feb 5;9(2):e87611. doi: 10.1371/journal.pone.0087611. eCollection 2014.


Sub-inhibitory concentrations of some antibiotics can drive diversification of Pseudomonas aeruginosa populations in artificial sputum medium.

Wright EA, Fothergill JL, Paterson S, Brockhurst MA, Winstanley C.

BMC Microbiol. 2013 Jul 23;13:170. doi: 10.1186/1471-2180-13-170.


Comparison of real time diagnostic chemistries to detect Pseudomonas aeruginosa in respiratory samples from cystic fibrosis patients.

Fothergill JL, Ledson MJ, Walshaw MJ, McNamara PS, Southern KW, Winstanley C.

J Cyst Fibros. 2013 Dec;12(6):675-81. doi: 10.1016/j.jcf.2013.04.007. Epub 2013 May 29.


Extensive diversification is a common feature of Pseudomonas aeruginosa populations during respiratory infections in cystic fibrosis.

Ashish A, Paterson S, Mowat E, Fothergill JL, Walshaw MJ, Winstanley C.

J Cyst Fibros. 2013 Dec;12(6):790-3. doi: 10.1016/j.jcf.2013.04.003. Epub 2013 May 1.


Intraclonal genetic diversity amongst cystic fibrosis and keratitis isolates of Pseudomonas aeruginosa.

Hall AJ, Fothergill JL, Kaye SB, Neal TJ, McNamara PS, Southern KW, Winstanley C.

J Med Microbiol. 2013 Feb;62(Pt 2):208-16. doi: 10.1099/jmm.0.048272-0. Epub 2012 Oct 25.


Differential infection properties of three inducible prophages from an epidemic strain of Pseudomonas aeruginosa.

James CE, Fothergill JL, Kalwij H, Hall AJ, Cottell J, Brockhurst MA, Winstanley C.

BMC Microbiol. 2012 Sep 21;12:216. doi: 10.1186/1471-2180-12-216.


Use of artificial sputum medium to test antibiotic efficacy against Pseudomonas aeruginosa in conditions more relevant to the cystic fibrosis lung.

Kirchner S, Fothergill JL, Wright EA, James CE, Mowat E, Winstanley C.

J Vis Exp. 2012 Jun 5;(64):e3857. doi: 10.3791/3857.


Novel therapeutic strategies to counter Pseudomonas aeruginosa infections.

Fothergill JL, Winstanley C, James CE.

Expert Rev Anti Infect Ther. 2012 Feb;10(2):219-35. doi: 10.1586/eri.11.168. Review.


Transmissible strains of Pseudomonas aeruginosa in cystic fibrosis lung infections.

Fothergill JL, Walshaw MJ, Winstanley C.

Eur Respir J. 2012 Jul;40(1):227-38. doi: 10.1183/09031936.00204411. Epub 2012 Feb 9.


Pseudomonas aeruginosa population diversity and turnover in cystic fibrosis chronic infections.

Mowat E, Paterson S, Fothergill JL, Wright EA, Ledson MJ, Walshaw MJ, Brockhurst MA, Winstanley C.

Am J Respir Crit Care Med. 2011 Jun 15;183(12):1674-9. doi: 10.1164/rccm.201009-1430OC. Epub 2011 Feb 4.


Effect of antibiotic treatment on bacteriophage production by a cystic fibrosis epidemic strain of Pseudomonas aeruginosa.

Fothergill JL, Mowat E, Walshaw MJ, Ledson MJ, James CE, Winstanley C.

Antimicrob Agents Chemother. 2011 Jan;55(1):426-8. doi: 10.1128/AAC.01257-10. Epub 2010 Oct 25.


A subtype of a Pseudomonas aeruginosa cystic fibrosis epidemic strain exhibits enhanced virulence in a murine model of acute respiratory infection.

Carter ME, Fothergill JL, Walshaw MJ, Rajakumar K, Kadioglu A, Winstanley C.

J Infect Dis. 2010 Sep 15;202(6):935-42. doi: 10.1086/655781.


Characterization of N-linked protein glycosylation in Helicobacter pullorum.

Jervis AJ, Langdon R, Hitchen P, Lawson AJ, Wood A, Fothergill JL, Morris HR, Dell A, Wren B, Linton D.

J Bacteriol. 2010 Oct;192(19):5228-36. doi: 10.1128/JB.00211-10. Epub 2010 Jun 25.


Impact of Pseudomonas aeruginosa genomic instability on the application of typing methods for chronic cystic fibrosis infections.

Fothergill JL, White J, Foweraker JE, Walshaw MJ, Ledson MJ, Mahenthiralingam E, Winstanley C.

J Clin Microbiol. 2010 Jun;48(6):2053-9. doi: 10.1128/JCM.00019-10. Epub 2010 Apr 21.


Empyema due to a highly transmissible Pseudomonas aeruginosa strain in an adult cystic fibrosis patient.

Mohan K, Lakshman V, Fothergill JL, Ledson MJ, Winstanley C, Walshaw MJ.

J Med Microbiol. 2010 May;59(Pt 5):614-6. doi: 10.1099/jmm.0.014696-0. Epub 2010 Feb 4.


Fluctuations in phenotypes and genotypes within populations of Pseudomonas aeruginosa in the cystic fibrosis lung during pulmonary exacerbations.

Fothergill JL, Mowat E, Ledson MJ, Walshaw MJ, Winstanley C.

J Med Microbiol. 2010 Apr;59(Pt 4):472-81. doi: 10.1099/jmm.0.015875-0. Epub 2009 Dec 17.


Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa.

Winstanley C, Langille MG, Fothergill JL, Kukavica-Ibrulj I, Paradis-Bleau C, Sanschagrin F, Thomson NR, Winsor GL, Quail MA, Lennard N, Bignell A, Clarke L, Seeger K, Saunders D, Harris D, Parkhill J, Hancock RE, Brinkman FS, Levesque RC.

Genome Res. 2009 Jan;19(1):12-23. doi: 10.1101/gr.086082.108. Epub 2008 Dec 1.


The role of quorum sensing in chronic cystic fibrosis Pseudomonas aeruginosa infections.

Winstanley C, Fothergill JL.

FEMS Microbiol Lett. 2009 Jan;290(1):1-9. doi: 10.1111/j.1574-6968.2008.01394.x. Epub 2008 Oct 29. Review.


Transmission of Pseudomonas aeruginosa epidemic strain from a patient with cystic fibrosis to a pet cat.

Mohan K, Fothergill JL, Storrar J, Ledson MJ, Winstanley C, Walshaw MJ.

Thorax. 2008 Sep;63(9):839-40. doi: 10.1136/thx.2007.092486.


Diagnostic multiplex PCR assay for the identification of the Liverpool, Midlands 1 and Manchester CF epidemic strains of Pseudomonas aeruginosa.

Fothergill JL, Upton AL, Pitt TL, Hart CA, Winstanley C.

J Cyst Fibros. 2008 May;7(3):258-61. Epub 2007 Oct 29.


Widespread pyocyanin over-production among isolates of a cystic fibrosis epidemic strain.

Fothergill JL, Panagea S, Hart CA, Walshaw MJ, Pitt TL, Winstanley C.

BMC Microbiol. 2007 May 23;7:45.

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