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CRISPR-Cas9 ribonucleoprotein-mediated co-editing and counterselection in the rice blast fungus.

Foster AJ, Martin-Urdiroz M, Yan X, Wright HS, Soanes DM, Talbot NJ.

Sci Rep. 2018 Sep 25;8(1):14355. doi: 10.1038/s41598-018-32702-w.


Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study.

Bell CC, Dankers ACA, Lauschke VM, Sison-Young R, Jenkins R, Rowe C, Goldring CE, Park K, Regan SL, Walker T, Schofield C, Baze A, Foster AJ, Williams DP, van de Ven AWM, Jacobs F, Houdt JV, Lähteenmäki T, Snoeys J, Juhila S, Richert L, Ingelman-Sundberg M.

Toxicol Sci. 2018 Apr 1;162(2):655-666. doi: 10.1093/toxsci/kfx289.


Lipidated Brartemicin Analogues Are Potent Th1-Stimulating Vaccine Adjuvants.

Foster AJ, Nagata M, Lu X, Lynch AT, Omahdi Z, Ishikawa E, Yamasaki S, Timmer MSM, Stocker BL.

J Med Chem. 2018 Feb 8;61(3):1045-1060. doi: 10.1021/acs.jmedchem.7b01468. Epub 2018 Jan 18.


Identification of factors involved in dimorphism and pathogenicity of Zymoseptoria tritici.

Yemelin A, Brauchler A, Jacob S, Laufer J, Heck L, Foster AJ, Antelo L, Andresen K, Thines E.

PLoS One. 2017 Aug 22;12(8):e0183065. doi: 10.1371/journal.pone.0183065. eCollection 2017.


Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury.

Proctor WR, Foster AJ, Vogt J, Summers C, Middleton B, Pilling MA, Shienson D, Kijanska M, Ströbel S, Kelm JM, Morgan P, Messner S, Williams D.

Arch Toxicol. 2017 Aug;91(8):2849-2863. doi: 10.1007/s00204-017-2002-1. Epub 2017 Jun 13.


Central-acting therapeutics alleviate respiratory weakness caused by heart failure-induced ventilatory overdrive.

Foster AJ, Platt MJ, Huber JS, Eadie AL, Arkell AM, Romanova N, Wright DC, Gillis TE, Murrant CL, Brunt KR, Simpson JA.

Sci Transl Med. 2017 May 17;9(390). pii: eaag1303. doi: 10.1126/scitranslmed.aag1303.


The role of glycerol in the pathogenic lifestyle of the rice blast fungus Magnaporthe oryzae.

Foster AJ, Ryder LS, Kershaw MJ, Talbot NJ.

Environ Microbiol. 2017 Mar;19(3):1008-1016. doi: 10.1111/1462-2920.13688. Epub 2017 Mar 1. Review.


Functions of the Magnaporthe oryzae Flb3p and Flb4p transcription factors in the regulation of conidiation.

Matheis S, Yemelin A, Scheps D, Andresen K, Jacob S, Thines E, Foster AJ.

Microbiol Res. 2017 Mar;196:106-117. doi: 10.1016/j.micres.2016.12.010. Epub 2016 Dec 30.


In Memoriam.

Foster AJ, Kelliher R, Mazzaschi AJ, Feiden K.

Public Health Rep. 2017 Jan/Feb;132(1):11-13. doi: 10.1177/0033354916683680. No abstract available.


Unravelling the biosynthesis of pyriculol in the rice blast fungus Magnaporthe oryzae.

Jacob S, Grötsch T, Foster AJ, Schüffler A, Rieger PH, Sandjo LP, Liermann JC, Opatz T, Thines E.

Microbiology. 2017 Apr;163(4):541-553. doi: 10.1099/mic.0.000396. Epub 2017 Apr 6.


Improved hepatic physiology in hepatic cytochrome P450 reductase null (HRN™) mice dosed orally with fenclozic acid.

Akingbasote JA, Foster AJ, Jones HB, David R, Gooderham NJ, Wilson ID, Kenna JG.

Toxicol Res (Camb). 2016 Nov 9;6(1):81-88. doi: 10.1039/c6tx00376a. eCollection 2017 Jan 1.


Cytotoxicity evaluation using cryopreserved primary human hepatocytes in various culture formats.

Richert L, Baze A, Parmentier C, Gerets HHJ, Sison-Young R, Dorau M, Lovatt C, Czich A, Goldring C, Park BK, Juhila S, Foster AJ, Williams DP.

Toxicol Lett. 2016 Sep 6;258:207-215. doi: 10.1016/j.toxlet.2016.06.1127. Epub 2016 Jun 27.


What Patients Really Want: Optimizing the Military Preoperative Evaluation Clinic.

Stoddard DR, Sebesta JA, Welder MD, Foster AJ, Rush RM.

Mil Med. 2016 Mar;181(3):236-42. doi: 10.7205/MILMED-D-15-00072.


A modular and compact portable mini-endstation for high-precision, high-speed fixed target serial crystallography at FEL and synchrotron sources.

Sherrell DA, Foster AJ, Hudson L, Nutter B, O'Hea J, Nelson S, Paré-Labrosse O, Oghbaey S, Miller RJ, Owen RL.

J Synchrotron Radiat. 2015 Nov;22(6):1372-8. doi: 10.1107/S1600577515016938. Epub 2015 Oct 6.


Transcriptome Analysis of Poplar during Leaf Spot Infection with Sphaerulina spp.

Foster AJ, Pelletier G, Tanguay P, Séguin A.

PLoS One. 2015 Sep 17;10(9):e0138162. doi: 10.1371/journal.pone.0138162. eCollection 2015.


Respiratory muscle weakness in the Zucker diabetic fatty rat.

Allwood MA, Foster AJ, Arkell AM, Beaudoin MS, Snook LA, Romanova N, Murrant CL, Holloway GP, Wright DC, Simpson JA.

Am J Physiol Regul Integr Comp Physiol. 2015 Oct;309(7):R780-7. doi: 10.1152/ajpregu.00447.2014. Epub 2015 Aug 5.


High osmolarity glycerol (HOG) signalling in Magnaporthe oryzae: Identification of MoYPD1 and its role in osmoregulation, fungicide action, and pathogenicity.

Jacob S, Foster AJ, Yemelin A, Thines E.

Fungal Biol. 2015 Jul;119(7):580-94. doi: 10.1016/j.funbio.2015.03.003. Epub 2015 Mar 14.


Hepatic effects of repeated oral administration of diclofenac to hepatic cytochrome P450 reductase null (HRN™) and wild-type mice.

Akingbasote JA, Foster AJ, Wilson I, Sarda S, Jones HB, Kenna JG.

Arch Toxicol. 2016 Apr;90(4):853-62. doi: 10.1007/s00204-015-1505-x. Epub 2015 Mar 28.


Multiple compound-related adverse properties contribute to liver injury caused by endothelin receptor antagonists.

Kenna JG, Stahl SH, Eakins JA, Foster AJ, Andersson LC, Bergare J, Billger M, Elebring M, Elmore CS, Thompson RA.

J Pharmacol Exp Ther. 2015 Feb;352(2):281-90. doi: 10.1124/jpet.114.220491. Epub 2014 Dec 2.


Histidine kinases mediate differentiation, stress response, and pathogenicity in Magnaporthe oryzae.

Jacob S, Foster AJ, Yemelin A, Thines E.

Microbiologyopen. 2014 Oct;3(5):668-87. doi: 10.1002/mbo3.197. Epub 2014 Aug 8.


Discovery of lipids from B. longum subsp. infantis using whole cell MALDI analysis.

Timmer MS, Sauvageau J, Foster AJ, Ryan J, Lagutin K, Shaw O, Harper JL, Sims IM, Stocker BL.

J Org Chem. 2014 Aug 15;79(16):7332-41. doi: 10.1021/jo501016c. Epub 2014 Aug 1.


Design, synthesis, and characterization of a 39 amino acid peptide mimic of the main immunogenic region of the Torpedo acetylcholine receptor.

Trinh VB, Foster AJ, Fairclough RH.

Mol Immunol. 2014 May;59(1):79-90. doi: 10.1016/j.molimm.2014.01.002. Epub 2014 Feb 1.


Prostaglandins induce vasodilatation of the microvasculature during muscle contraction and induce vasodilatation independent of adenosine.

Murrant CL, Dodd JD, Foster AJ, Inch KA, Muckle FR, Ruiz DA, Simpson JA, Scholl JH.

J Physiol. 2014 Mar 15;592(6):1267-81. doi: 10.1113/jphysiol.2013.264259. Epub 2014 Jan 27.


Evaluation of the use of imaging parameters for the detection of compound-induced hepatotoxicity in 384-well cultures of HepG2 cells and cryopreserved primary human hepatocytes.

Garside H, Marcoe KF, Chesnut-Speelman J, Foster AJ, Muthas D, Kenna JG, Warrior U, Bowes J, Baumgartner J.

Toxicol In Vitro. 2014 Mar;28(2):171-81. doi: 10.1016/j.tiv.2013.10.015. Epub 2013 Nov 1.


A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans.

Gustafsson F, Foster AJ, Sarda S, Bridgland-Taylor MH, Kenna JG.

Toxicol Sci. 2014 Jan;137(1):189-211. doi: 10.1093/toxsci/kft223. Epub 2013 Oct 1.


Antiretroviral solid drug nanoparticles with enhanced oral bioavailability: production, characterization, and in vitro-in vivo correlation.

McDonald TO, Giardiello M, Martin P, Siccardi M, Liptrott NJ, Smith D, Roberts P, Curley P, Schipani A, Khoo SH, Long J, Foster AJ, Rannard SP, Owen A.

Adv Healthc Mater. 2014 Mar;3(3):400-11. doi: 10.1002/adhm.201300280. Epub 2013 Sep 1.


The role of the Tra1p transcription factor of Magnaporthe oryzae in spore adhesion and pathogenic development.

Breth B, Odenbach D, Yemelin A, Schlinck N, Schröder M, Bode M, Antelo L, Andresen K, Thines E, Foster AJ.

Fungal Genet Biol. 2013 Aug;57:11-22. doi: 10.1016/j.fgb.2013.05.008. Epub 2013 May 31.


Glutathione metabolism modeling: a mechanism for liver drug-robustness and a new biomarker strategy.

Geenen S, du Preez FB, Snoep JL, Foster AJ, Sarda S, Kenna JG, Wilson ID, Westerhoff HV.

Biochim Biophys Acta. 2013 Oct;1830(10):4943-59. doi: 10.1016/j.bbagen.2013.04.014. Epub 2013 Apr 30.


Identification of genes in Thuja plicata foliar terpenoid defenses.

Foster AJ, Hall DE, Mortimer L, Abercromby S, Gries R, Gries G, Bohlmann J, Russell J, Mattsson J.

Plant Physiol. 2013 Apr;161(4):1993-2004. doi: 10.1104/pp.112.206383. Epub 2013 Feb 6.


Bioactivation of the cannabinoid receptor antagonist rimonabant to a cytotoxic iminium ion metabolite.

Foster AJ, Prime LH, Gustafsson F, Temesi DG, Isin EM, Midlöv J, Castagnoli N Jr, Kenna JG.

Chem Res Toxicol. 2013 Jan 18;26(1):124-35. doi: 10.1021/tx300418w. Epub 2012 Dec 12.


Synthesis and biological activity of the lipoteichoic acid anchor from Streptococcus sp. DSM 8747.

Sauvageau J, Foster AJ, Khan AA, Chee SH, Sims IM, Timmer MS, Stocker BL.

Chembiochem. 2012 Nov 5;13(16):2416-24. doi: 10.1002/cbic.201200468. Epub 2012 Oct 11.


Characterization of THLE-cytochrome P450 (P450) cell lines: gene expression background and relationship to P450-enzyme activity.

Soltanpour Y, Hilgendorf C, Ahlström MM, Foster AJ, Kenna JG, Petersen A, Ungell AL.

Drug Metab Dispos. 2012 Nov;40(11):2054-8. doi: 10.1124/dmd.112.045815. Epub 2012 Jul 30.


In vitro approach to assess the potential for risk of idiosyncratic adverse reactions caused by candidate drugs.

Thompson RA, Isin EM, Li Y, Weidolf L, Page K, Wilson I, Swallow S, Middleton B, Stahl S, Foster AJ, Dolgos H, Weaver R, Kenna JG.

Chem Res Toxicol. 2012 Aug 20;25(8):1616-32. doi: 10.1021/tx300091x. Epub 2012 May 31.


Finished genome of the fungal wheat pathogen Mycosphaerella graminicola reveals dispensome structure, chromosome plasticity, and stealth pathogenesis.

Goodwin SB, M'barek SB, Dhillon B, Wittenberg AH, Crane CF, Hane JK, Foster AJ, Van der Lee TA, Grimwood J, Aerts A, Antoniw J, Bailey A, Bluhm B, Bowler J, Bristow J, van der Burgt A, Canto-Canché B, Churchill AC, Conde-Ferràez L, Cools HJ, Coutinho PM, Csukai M, Dehal P, De Wit P, Donzelli B, van de Geest HC, van Ham RC, Hammond-Kosack KE, Henrissat B, Kilian A, Kobayashi AK, Koopmann E, Kourmpetis Y, Kuzniar A, Lindquist E, Lombard V, Maliepaard C, Martins N, Mehrabi R, Nap JP, Ponomarenko A, Rudd JJ, Salamov A, Schmutz J, Schouten HJ, Shapiro H, Stergiopoulos I, Torriani SF, Tu H, de Vries RP, Waalwijk C, Ware SB, Wiebenga A, Zwiers LH, Oliver RP, Grigoriev IV, Kema GH.

PLoS Genet. 2011 Jun;7(6):e1002070. doi: 10.1371/journal.pgen.1002070. Epub 2011 Jun 9.


Identifying reaction intermediates and catalytic active sites through in situ characterization techniques.

Foster AJ, Lobo RF.

Chem Soc Rev. 2010 Dec;39(12):4783-93. doi: 10.1039/c0cs00016g. Epub 2010 Nov 1.


MAP kinase signalling pathway components and targets conserved between the distantly related plant pathogenic fungi Mycosphaerella graminicola and Magnaporthe grisea.

Kramer B, Thines E, Foster AJ.

Fungal Genet Biol. 2009 Sep;46(9):667-81. doi: 10.1016/j.fgb.2009.06.001. Epub 2009 Jun 9.


Siderophore synthesis in Magnaporthe grisea is essential for vegetative growth, conidiation and resistance to oxidative stress.

Hof C, Eisfeld K, Antelo L, Foster AJ, Anke H.

Fungal Genet Biol. 2009 Apr;46(4):321-32. doi: 10.1016/j.fgb.2008.12.004. Epub 2008 Dec 31.


The Magnaporthe grisea class VII chitin synthase is required for normal appressorial development and function.

Odenbach D, Thines E, Anke H, Foster AJ.

Mol Plant Pathol. 2009 Jan;10(1):81-94. doi: 10.1111/j.1364-3703.2008.00515.x.


Formation and enhanced biocidal activity of water-dispersable organic nanoparticles.

Zhang H, Wang D, Butler R, Campbell NL, Long J, Tan B, Duncalf DJ, Foster AJ, Hopkinson A, Taylor D, Angus D, Cooper AI, Rannard SP.

Nat Nanotechnol. 2008 Aug;3(8):506-11. doi: 10.1038/nnano.2008.188. Epub 2008 Jul 6.


Microprobe XRF mapping and XAS investigations of the intracellular metabolism of arsenic for understanding arsenic-induced toxicity.

Munro KL, Mariana A, Klavins AI, Foster AJ, Lai B, Vogt S, Cai Z, Harris HH, Dillon CT.

Chem Res Toxicol. 2008 Sep;21(9):1760-9. doi: 10.1021/tx800128d. Epub 2008 Jul 3.


Biotinylation and characterization of Cryptococcus neoformans cell surface proteins.

Foster AJ, Bird RA, Smith SN.

J Appl Microbiol. 2007 Aug;103(2):390-9.


The Partners in Information Access for the Public Health Workforce: a collaboration to improve and protect the public's health, 1995-2006.

Cahn MA, Auston I, Selden CR, Cogdill K, Baker S, Cavanaugh D, Elliott S, Foster AJ, Leep CJ, Perez DJ, Pomietto BR.

J Med Libr Assoc. 2007 Jul;95(3):301-9.


The transcription factor Con7p is a central regulator of infection-related morphogenesis in the rice blast fungus Magnaporthe grisea.

Odenbach D, Breth B, Thines E, Weber RW, Anke H, Foster AJ.

Mol Microbiol. 2007 Apr;64(2):293-307. Epub 2007 Mar 23.


Ferricrocin synthesis in Magnaporthe grisea and its role in pathogenicity in rice.

Hof C, Eisfeld K, Welzel K, Antelo L, Foster AJ, Anke H.

Mol Plant Pathol. 2007 Mar;8(2):163-72. doi: 10.1111/j.1364-3703.2007.00380.x.


The results of immediate re-repair of zone 1 and 2 primary flexor tendon repairs which rupture.

Dowd MB, Figus A, Harris SB, Southgate CM, Foster AJ, Elliot D.

J Hand Surg Br. 2006 Oct;31(5):507-13. Epub 2006 Aug 22.


Genotoxicity and transmission electron microscopy studies of molybdocene dichloride.

Campbell KS, Foster AJ, Dillon CT, Harding MM.

J Inorg Biochem. 2006 Jul;100(7):1194-8. Epub 2006 Mar 9.


Immediate repair and early mobilization of the extensor pollicis longus tendon in zones 1 to 4.

Khandwala AR, Blair J, Harris SB, Foster AJ, Elliot D.

J Hand Surg Br. 2004 Jun;29(3):250-8.


FITC-lectin avidity of Cryptococcus neoformans cell wall and capsular components.

Foster AJ, Bird RA, Kelly SL, Nishimura K, Poyner D, Taylor S, Smith SN.

Mycologia. 2004 Jan-Feb;96(1):1-8.


A comparison of dynamic extension splinting and controlled active mobilization of complete divisions of extensor tendons in zones 5 and 6.

Khandwala AR, Webb J, Harris SB, Foster AJ, Elliot D.

J Hand Surg Br. 2000 Apr;25(2):140-6.


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