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Items: 1 to 50 of 156

1.

Publisher Correction: Targeting hepatic glutaminase activity to ameliorate hyperglycemia.

Miller RA, Shi Y, Lu W, Pirman DA, Jatkar A, Blatnik M, Wu H, Cárdenas C, Wan M, Foskett JK, Park JO, Zhang Y, Holland WL, Rabinowitz JD, Birnbaum MJ.

Nat Med. 2018 Sep;24(9):1482. doi: 10.1038/s41591-018-0047-1.

PMID:
29895835
2.

CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes.

Ma Z, Taruno A, Ohmoto M, Jyotaki M, Lim JC, Miyazaki H, Niisato N, Marunaka Y, Lee RJ, Hoff H, Payne R, Demuro A, Parker I, Mitchell CH, Henao-Mejia J, Tanis JE, Matsumoto I, Tordoff MG, Foskett JK.

Neuron. 2018 May 2;98(3):547-561.e10. doi: 10.1016/j.neuron.2018.03.043. Epub 2018 Apr 19.

3.

Targeting hepatic glutaminase activity to ameliorate hyperglycemia.

Miller RA, Shi Y, Lu W, Pirman DA, Jatkar A, Blatnik M, Wu H, Cárdenas C, Wan M, Foskett JK, Park JO, Zhang Y, Holland WL, Rabinowitz JD, Birnbaum MJ.

Nat Med. 2018 May;24(4):518-524. doi: 10.1038/nm.4514. Epub 2018 Mar 26. Erratum in: Nat Med. 2018 Jun 12;:.

4.

MICU2 Restricts Spatial Crosstalk between InsP3R and MCU Channels by Regulating Threshold and Gain of MICU1-Mediated Inhibition and Activation of MCU.

Payne R, Hoff H, Roskowski A, Foskett JK.

Cell Rep. 2017 Dec 12;21(11):3141-3154. doi: 10.1016/j.celrep.2017.11.064.

5.

Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening.

Arduino DM, Wettmarshausen J, Vais H, Navas-Navarro P, Cheng Y, Leimpek A, Ma Z, Delrio-Lorenzo A, Giordano A, Garcia-Perez C, Médard G, Kuster B, García-Sancho J, Mokranjac D, Foskett JK, Alonso MT, Perocchi F.

Mol Cell. 2017 Aug 17;67(4):711-723.e7. doi: 10.1016/j.molcel.2017.07.019.

6.

The NH2 terminus regulates voltage-dependent gating of CALHM ion channels.

Tanis JE, Ma Z, Foskett JK.

Am J Physiol Cell Physiol. 2017 Aug 1;313(2):C173-C186. doi: 10.1152/ajpcell.00318.2016. Epub 2017 May 17.

7.

Action potentials and ion conductances in wild-type and CALHM1-knockout type II taste cells.

Ma Z, Saung WT, Foskett JK.

J Neurophysiol. 2017 May 1;117(5):1865-1876. doi: 10.1152/jn.00835.2016. Epub 2017 Feb 15.

8.

CFTR nonsense mutations: Therapeutic benefits from clinically approved drugs?

Foskett JK.

J Cyst Fibros. 2017 Jan;16(1):9-10. doi: 10.1016/j.jcf.2016.12.005. Epub 2016 Dec 10. No abstract available.

9.

Ryanodine receptor resolution revolution: Implications for InsP3 receptors?

Mak DD, Foskett JK.

Cell Calcium. 2017 Jan;61:53-56. doi: 10.1016/j.ceca.2016.11.002. Epub 2016 Nov 6. No abstract available.

10.

InsP3R, the calcium whisperer: Maintaining mitochondrial function in cancer.

Lovy A, Foskett JK, Cárdenas C.

Mol Cell Oncol. 2016 May 11;3(4):e1185563. doi: 10.1080/23723556.2016.1185563. eCollection 2016 Jul.

11.

Familial Alzheimer's disease-associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca2+ entry.

Tong BC, Lee CS, Cheng WH, Lai KO, Foskett JK, Cheung KH.

Sci Signal. 2016 Sep 6;9(444):ra89. doi: 10.1126/scisignal.aaf1371.

12.

Selective Vulnerability of Cancer Cells by Inhibition of Ca(2+) Transfer from Endoplasmic Reticulum to Mitochondria.

Cárdenas C, Müller M, McNeal A, Lovy A, Jaňa F, Bustos G, Urra F, Smith N, Molgó J, Diehl JA, Ridky TW, Foskett JK.

Cell Rep. 2016 Apr 5;15(1):219-220. doi: 10.1016/j.celrep.2016.03.045. No abstract available.

13.

Biphasic regulation of InsP3 receptor gating by dual Ca2+ release channel BH3-like domains mediates Bcl-xL control of cell viability.

Yang J, Vais H, Gu W, Foskett JK.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):E1953-62. doi: 10.1073/pnas.1517935113. Epub 2016 Mar 14.

14.

Selective Vulnerability of Cancer Cells by Inhibition of Ca(2+) Transfer from Endoplasmic Reticulum to Mitochondria.

Cárdenas C, Müller M, McNeal A, Lovy A, Jaňa F, Bustos G, Urra F, Smith N, Molgó J, Diehl JA, Ridky TW, Foskett JK.

Cell Rep. 2016 Mar 15;14(10):2313-24. doi: 10.1016/j.celrep.2016.02.030. Epub 2016 Mar 3. Erratum in: Cell Rep. 2016 Apr 5;15(1):219-20.

15.

EMRE Is a Matrix Ca(2+) Sensor that Governs Gatekeeping of the Mitochondrial Ca(2+) Uniporter.

Vais H, Mallilankaraman K, Mak DD, Hoff H, Payne R, Tanis JE, Foskett JK.

Cell Rep. 2016 Jan 26;14(3):403-410. doi: 10.1016/j.celrep.2015.12.054. Epub 2016 Jan 7.

16.

Calcium homeostasis modulator (CALHM) ion channels.

Ma Z, Tanis JE, Taruno A, Foskett JK.

Pflugers Arch. 2016 Mar;468(3):395-403. doi: 10.1007/s00424-015-1757-6. Epub 2015 Nov 25. Review.

17.

MCUR1, CCDC90A, Is a Regulator of the Mitochondrial Calcium Uniporter.

Vais H, Tanis JE, Müller M, Payne R, Mallilankaraman K, Foskett JK.

Cell Metab. 2015 Oct 6;22(4):533-5. doi: 10.1016/j.cmet.2015.09.015. No abstract available.

18.

Analyzing and Quantifying the Gain-of-Function Enhancement of IP3 Receptor Gating by Familial Alzheimer's Disease-Causing Mutants in Presenilins.

Mak DO, Cheung KH, Toglia P, Foskett JK, Ullah G.

PLoS Comput Biol. 2015 Oct 6;11(10):e1004529. doi: 10.1371/journal.pcbi.1004529. eCollection 2015 Oct.

19.

MCUR1 is an essential component of mitochondrial Ca(2+) uptake that regulates cellular metabolism.

Mallilankaraman K, Cárdenas C, Doonan PJ, Chandramoorthy HC, Irrinki KM, Golenár T, Csordás G, Madireddi P, Yang J, Müller M, Miller R, Kolesar JE, Molgó J, Kaufman B, Hajnóczky G, Foskett JK, Madesh M.

Nat Cell Biol. 2015 Jul;17(7):953. doi: 10.1038/ncb3202. No abstract available.

PMID:
26123113
20.

Normal Taste Acceptance and Preference of PANX1 Knockout Mice.

Tordoff MG, Aleman TR, Ellis HT, Ohmoto M, Matsumoto I, Shestopalov VI, Mitchell CH, Foskett JK, Poole RL.

Chem Senses. 2015 Sep;40(7):453-9. doi: 10.1093/chemse/bjv025. Epub 2015 May 18.

21.

Inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum: A single-channel point of view.

Mak DO, Foskett JK.

Cell Calcium. 2015 Jul;58(1):67-78. doi: 10.1016/j.ceca.2014.12.008. Epub 2014 Dec 18. Review.

22.

The mitochondrial Ca(2+) uniporter complex.

Foskett JK, Philipson B.

J Mol Cell Cardiol. 2015 Jan;78:3-8. doi: 10.1016/j.yjmcc.2014.11.015. Epub 2014 Nov 22. Review.

23.

Effect of the CALHM1 G330D and R154H human variants on the control of cytosolic Ca2+ and Aβ levels.

Vingtdeux V, Tanis JE, Chandakkar P, Zhao H, Dreses-Werringloer U, Campagne F, Foskett JK, Marambaud P.

PLoS One. 2014 Nov 11;9(11):e112484. doi: 10.1371/journal.pone.0112484. eCollection 2014.

24.

LETM1-dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation.

Doonan PJ, Chandramoorthy HC, Hoffman NE, Zhang X, Cárdenas C, Shanmughapriya S, Rajan S, Vallem S, Chen X, Foskett JK, Cheung JY, Houser SR, Madesh M.

FASEB J. 2014 Nov;28(11):4936-49. doi: 10.1096/fj.14-256453. Epub 2014 Jul 30. Erratum in: FASEB J. 2015 Aug;29(8):3593.

25.

General anesthetic isoflurane modulates inositol 1,4,5-trisphosphate receptor calcium channel opening.

Joseph JD, Peng Y, Mak DO, Cheung KH, Vais H, Foskett JK, Wei H.

Anesthesiology. 2014 Sep;121(3):528-37. doi: 10.1097/ALN.0000000000000316.

26.

Salty taste deficits in CALHM1 knockout mice.

Tordoff MG, Ellis HT, Aleman TR, Downing A, Marambaud P, Foskett JK, Dana RM, McCaughey SA.

Chem Senses. 2014 Jul;39(6):515-28. doi: 10.1093/chemse/bju020. Epub 2014 May 20.

27.

Suppression of InsP3 receptor-mediated Ca2+ signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis.

Shilling D, Müller M, Takano H, Mak DO, Abel T, Coulter DA, Foskett JK.

J Neurosci. 2014 May 14;34(20):6910-23. doi: 10.1523/JNEUROSCI.5441-13.2014.

28.

Regulation of the mitochondrial Ca(2+) uniporter by MICU1 and MICU2.

Foskett JK, Madesh M.

Biochem Biophys Res Commun. 2014 Jul 11;449(4):377-83. doi: 10.1016/j.bbrc.2014.04.146. Epub 2014 May 1. No abstract available.

29.

Ca²⁺ signaling and fluid secretion by secretory cells of the airway epithelium.

Lee RJ, Foskett JK.

Cell Calcium. 2014 Jun;55(6):325-36. doi: 10.1016/j.ceca.2014.02.001. Epub 2014 Feb 11. Review.

PMID:
24703093
30.

Phosphorylated K-Ras limits cell survival by blocking Bcl-xL sensitization of inositol trisphosphate receptors.

Sung PJ, Tsai FD, Vais H, Court H, Yang J, Fehrenbacher N, Foskett JK, Philips MR.

Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20593-8. doi: 10.1073/pnas.1306431110. Epub 2013 Dec 2.

31.

How do taste cells lacking synapses mediate neurotransmission? CALHM1, a voltage-gated ATP channel.

Taruno A, Matsumoto I, Ma Z, Marambaud P, Foskett JK.

Bioessays. 2013 Dec;35(12):1111-8. doi: 10.1002/bies.201300077. Epub 2013 Sep 17. Review.

32.

Nuclear patch-clamp electrophysiology of Ca2+ channels.

Mak DO, Vais H, Cheung KH, Foskett JK.

Cold Spring Harb Protoc. 2013 Sep 1;2013(9):885-91. doi: 10.1101/pdb.prot073064.

33.

Isolating nuclei from cultured cells for patch-clamp electrophysiology of intracellular Ca(2+) channels.

Mak DO, Vais H, Cheung KH, Foskett JK.

Cold Spring Harb Protoc. 2013 Sep 1;2013(9):880-4. doi: 10.1101/pdb.prot073056.

34.

Patch-clamp electrophysiology of intracellular Ca2+ channels.

Mak DO, Vais H, Cheung KH, Foskett JK.

Cold Spring Harb Protoc. 2013 Sep 1;2013(9):787-97. doi: 10.1101/pdb.top066217.

35.

CLHM-1 is a functionally conserved and conditionally toxic Ca2+-permeable ion channel in Caenorhabditis elegans.

Tanis JE, Ma Z, Krajacic P, He L, Foskett JK, Lamitina T.

J Neurosci. 2013 Jul 24;33(30):12275-86. doi: 10.1523/JNEUROSCI.5919-12.2013.

36.

CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes.

Taruno A, Vingtdeux V, Ohmoto M, Ma Z, Dvoryanchikov G, Li A, Adrien L, Zhao H, Leung S, Abernethy M, Koppel J, Davies P, Civan MM, Chaudhari N, Matsumoto I, Hellekant G, Tordoff MG, Marambaud P, Foskett JK.

Nature. 2013 Mar 14;495(7440):223-6. doi: 10.1038/nature11906. Epub 2013 Mar 6.

37.

A host GPCR signaling network required for the cytolysis of infected cells facilitates release of apicomplexan parasites.

Millholland MG, Mishra S, Dupont CD, Love MS, Patel B, Shilling D, Kazanietz MG, Foskett JK, Hunter CA, Sinnis P, Greenbaum DC.

Cell Host Microbe. 2013 Jan 16;13(1):15-28. doi: 10.1016/j.chom.2012.12.001. Epub 2013 Jan 16.

38.

Structural and functional similarities of calcium homeostasis modulator 1 (CALHM1) ion channel with connexins, pannexins, and innexins.

Siebert AP, Ma Z, Grevet JD, Demuro A, Parker I, Foskett JK.

J Biol Chem. 2013 Mar 1;288(9):6140-53. doi: 10.1074/jbc.M112.409789. Epub 2013 Jan 8.

39.

MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism.

Mallilankaraman K, Cárdenas C, Doonan PJ, Chandramoorthy HC, Irrinki KM, Golenár T, Csordás G, Madireddi P, Yang J, Müller M, Miller R, Kolesar JE, Molgó J, Kaufman B, Hajnóczky G, Foskett JK, Madesh M.

Nat Cell Biol. 2012 Dec;14(12):1336-43. doi: 10.1038/ncb2622. Epub 2012 Nov 25. Erratum in: Nat Cell Biol. 2013 Jan;15(1):123. Nat Cell Biol. 2015 Jul;17(7):953.

40.

Permeant calcium ion feed-through regulation of single inositol 1,4,5-trisphosphate receptor channel gating.

Vais H, Foskett JK, Ullah G, Pearson JE, Mak DO.

J Gen Physiol. 2012 Dec;140(6):697-716. doi: 10.1085/jgp.201210804. Epub 2012 Nov 12.

41.

MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival.

Mallilankaraman K, Doonan P, Cárdenas C, Chandramoorthy HC, Müller M, Miller R, Hoffman NE, Gandhirajan RK, Molgó J, Birnbaum MJ, Rothberg BS, Mak DO, Foskett JK, Madesh M.

Cell. 2012 Oct 26;151(3):630-44. doi: 10.1016/j.cell.2012.10.011.

42.

Why mouse airway submucosal gland serous cells do not secrete fluid in response to cAMP stimulation.

Lee RJ, Foskett JK.

J Biol Chem. 2012 Nov 2;287(45):38316-26. doi: 10.1074/jbc.M112.412817. Epub 2012 Sep 18.

43.

Role of binding and nucleoside diphosphate kinase A in the regulation of the cystic fibrosis transmembrane conductance regulator by AMP-activated protein kinase.

King JD Jr, Lee J, Riemen CE, Neumann D, Xiong S, Foskett JK, Mehta A, Muimo R, Hallows KR.

J Biol Chem. 2012 Sep 28;287(40):33389-400. Epub 2012 Aug 6.

44.

Calpain-cleaved type 1 inositol 1,4,5-trisphosphate receptor impairs ER Ca(2+) buffering and causes neurodegeneration in primary cortical neurons.

Kopil CM, Siebert AP, Foskett JK, Neumar RW.

J Neurochem. 2012 Oct;123(1):147-58. doi: 10.1111/j.1471-4159.2012.07859.x. Epub 2012 Aug 14.

45.

Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability.

Ma Z, Siebert AP, Cheung KH, Lee RJ, Johnson B, Cohen AS, Vingtdeux V, Marambaud P, Foskett JK.

Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):E1963-71. doi: 10.1073/pnas.1204023109. Epub 2012 Jun 18.

46.

Mitochondrial Ca(2+) signals in autophagy.

Cárdenas C, Foskett JK.

Cell Calcium. 2012 Jul;52(1):44-51. doi: 10.1016/j.ceca.2012.03.001. Epub 2012 Mar 28. Review.

47.

Lack of evidence for presenilins as endoplasmic reticulum Ca2+ leak channels.

Shilling D, Mak DO, Kang DE, Foskett JK.

J Biol Chem. 2012 Mar 30;287(14):10933-44. doi: 10.1074/jbc.M111.300491. Epub 2012 Feb 6.

48.

InsP3R channel gating altered by clustering?

Vais H, Foskett JK, Mak DO.

Nature. 2011 Oct 12;478(7368):E1-2; discussion E2-3. doi: 10.1038/nature10493. No abstract available.

49.

Calpain-cleaved type 1 inositol 1,4,5-trisphosphate receptor (InsP(3)R1) has InsP(3)-independent gating and disrupts intracellular Ca(2+) homeostasis.

Kopil CM, Vais H, Cheung KH, Siebert AP, Mak DO, Foskett JK, Neumar RW.

J Biol Chem. 2011 Oct 14;286(41):35998-6010. doi: 10.1074/jbc.M111.254177. Epub 2011 Aug 22.

50.

Constitutive cAMP response element binding protein (CREB) activation by Alzheimer's disease presenilin-driven inositol trisphosphate receptor (InsP3R) Ca2+ signaling.

Müller M, Cárdenas C, Mei L, Cheung KH, Foskett JK.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13293-8. doi: 10.1073/pnas.1109297108. Epub 2011 Jul 22.

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