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Items: 1 to 50 of 83

1.

Structural characterization of a short-chain dehydrogenase/reductase from multi-drug resistant Acinetobacter baumannii.

Cross EM, Aragão D, Smith KM, Shaw KI, Nanson JD, Raidal SR, Forwood JK.

Biochem Biophys Res Commun. 2019 Aug 20. pii: S0006-291X(19)31573-6. doi: 10.1016/j.bbrc.2019.08.056. [Epub ahead of print]

PMID:
31443964
2.

Lysine-Specific Histone Demethylase 1A Regulates Macrophage Polarization and Checkpoint Molecules in the Tumor Microenvironment of Triple-Negative Breast Cancer.

Tan AHY, Tu W, McCuaig R, Hardy K, Donovan T, Tsimbalyuk S, Forwood JK, Rao S.

Front Immunol. 2019 Jun 12;10:1351. doi: 10.3389/fimmu.2019.01351. eCollection 2019.

3.

Structural characterization of β-ketoacyl ACP synthase I bound to platencin and fragment screening molecules at two substrate binding sites.

Patterson EI, Nanson JD, Abendroth J, Bryan C, Sankaran B, Myler PJ, Forwood JK.

Proteins. 2019 Jun 25. doi: 10.1002/prot.25765. [Epub ahead of print]

PMID:
31237717
4.

Pigeon circoviruses from feral pigeons in Australia demonstrate extensive recombination and genetic admixture with other circoviruses.

Sarker S, Das S, Ghorashi SA, Forwood JK, Raidal SR.

Avian Pathol. 2019 Jul 11:1-9. doi: 10.1080/03079457.2019.1629391. [Epub ahead of print]

PMID:
31199167
5.

Novel Flavivirus Antiviral That Targets the Host Nuclear Transport Importin α/β1 Heterodimer.

Yang SNY, Atkinson SC, Fraser JE, Wang C, Maher B, Roman N, Forwood JK, Wagstaff KM, Borg NA, Jans DA.

Cells. 2019 Mar 24;8(3). pii: E281. doi: 10.3390/cells8030281.

6.

Zika Virus NS5 Forms Supramolecular Nuclear Bodies That Sequester Importin-α and Modulate the Host Immune and Pro-Inflammatory Response in Neuronal Cells.

Ng IHW, Chan KW, Tan MJA, Gwee CP, Smith KM, Jeffress SJ, Saw WG, Swarbrick CMD, Watanabe S, Jans DA, Grüber G, Forwood JK, Vasudevan SG.

ACS Infect Dis. 2019 Jun 14;5(6):932-948. doi: 10.1021/acsinfecdis.8b00373. Epub 2019 Mar 19.

PMID:
30848123
7.

Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.

Smith KM, Tsimbalyuk S, Edwards MR, Cross EM, Batra J, Soares da Costa TP, Aragão D, Basler CF, Forwood JK.

Nat Commun. 2018 Sep 12;9(1):3703. doi: 10.1038/s41467-018-05928-5.

8.

Contribution of the residue at position 4 within classical nuclear localization signals to modulating interaction with importins and nuclear targeting.

Smith KM, Di Antonio V, Bellucci L, Thomas DR, Caporuscio F, Ciccarese F, Ghassabian H, Wagstaff KM, Forwood JK, Jans DA, Palù G, Alvisi G.

Biochim Biophys Acta Mol Cell Res. 2018 Aug;1865(8):1114-1129. doi: 10.1016/j.bbamcr.2018.05.006. Epub 2018 May 8.

9.

LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer.

Boulding T, McCuaig RD, Tan A, Hardy K, Wu F, Dunn J, Kalimutho M, Sutton CR, Forwood JK, Bert AG, Goodall GJ, Malik L, Yip D, Dahlstrom JE, Zafar A, Khanna KK, Rao S.

Sci Rep. 2018 Jan 8;8(1):73. doi: 10.1038/s41598-017-17913-x.

10.

Molecular and microscopic characterization of a novel Eastern grey kangaroopox virus genome directly from a clinical sample.

Sarker S, Roberts HK, Tidd N, Ault S, Ladmore G, Peters A, Forwood JK, Helbig K, Raidal SR.

Sci Rep. 2017 Nov 28;7(1):16472. doi: 10.1038/s41598-017-16775-7.

11.

Nuclear import inhibitor N-(4-hydroxyphenyl) retinamide targets Zika virus (ZIKV) nonstructural protein 5 to inhibit ZIKV infection.

Wang C, Yang SNY, Smith K, Forwood JK, Jans DA.

Biochem Biophys Res Commun. 2017 Dec 2;493(4):1555-1559. doi: 10.1016/j.bbrc.2017.10.016. Epub 2017 Oct 4.

PMID:
28988109
12.

Structural insights into GDP-mediated regulation of a bacterial acyl-CoA thioesterase.

Khandokar YB, Srivastava P, Cowieson N, Sarker S, Aragao D, Das S, Smith KM, Raidal SR, Forwood JK.

J Biol Chem. 2017 Dec 15;292(50):20461-20471. doi: 10.1074/jbc.M117.800227. Epub 2017 Oct 2.

13.

Structural Basis for Importin-α Binding of the Human Immunodeficiency Virus Tat.

Smith KM, Himiari Z, Tsimbalyuk S, Forwood JK.

Sci Rep. 2017 May 10;7(1):1650. doi: 10.1038/s41598-017-01853-7.

14.

Mycobacteria Encode Active and Inactive Classes of TesB Fatty-Acyl CoA Thioesterases Revealed through Structural and Functional Analysis.

Swarbrick CM, Bythrow GV, Aragao D, Germain GA, Quadri LE, Forwood JK.

Biochemistry. 2017 Mar 14;56(10):1460-1472. doi: 10.1021/acs.biochem.6b01049. Epub 2017 Mar 2.

PMID:
28156101
15.

A novel pathogenic aviadenovirus from red-bellied parrots (Poicephalus rufiventris) unveils deep recombination events among avian host lineages.

Das S, Fearnside K, Sarker S, Forwood JK, Raidal SR.

Virology. 2017 Feb;502:188-197. doi: 10.1016/j.virol.2016.12.031. Epub 2017 Jan 4.

16.

Structural characterisation of the fatty acid biosynthesis enzyme FabF from the pathogen Listeria monocytogenes.

Soares da Costa TP, Nanson JD, Forwood JK.

Sci Rep. 2017 Jan 3;7:39277. doi: 10.1038/srep39277.

17.

Characterization of Beak and Feather Disease Virus Genomes from Wild Musk Lorikeets (Glossopsitta concinna).

Das S, Subir S, Adriaanse K, Forwood JK, Ghorashi SA, Raidal SR.

Genome Announc. 2016 Oct 6;4(5). pii: e01107-16. doi: 10.1128/genomeA.01107-16.

18.

Molecular Characterization of a Beak and Feather Disease Virus Genome from a Purple Crowned Lorikeet (Glossopsitta porphyrocephala).

Das S, Subir S, Fearnside K, Forwood JK, Ghorashi SA, Raidal SR.

Genome Announc. 2016 Oct 6;4(5). pii: e01102-16. doi: 10.1128/genomeA.01102-16.

19.

Whole-Genome Sequence of a Beak and Feather Disease Virus Isolate from a Fledgling Red-Capped Parrot (Purpureicephalus spurius).

Das S, Subir S, Forwood JK, Ghorashi SA, Raidal SR.

Genome Announc. 2016 Oct 13;4(5). pii: e01108-16. doi: 10.1128/genomeA.01108-16.

20.

Structural insights into the assembly and regulation of distinct viral capsid complexes.

Sarker S, Terrón MC, Khandokar Y, Aragão D, Hardy JM, Radjainia M, Jiménez-Zaragoza M, de Pablo PJ, Coulibaly F, Luque D, Raidal SR, Forwood JK.

Nat Commun. 2016 Oct 4;7:13014. doi: 10.1038/ncomms13014.

21.

The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production.

Tay MY, Smith K, Ng IH, Chan KW, Zhao Y, Ooi EE, Lescar J, Luo D, Jans DA, Forwood JK, Vasudevan SG.

PLoS Pathog. 2016 Sep 13;12(9):e1005886. doi: 10.1371/journal.ppat.1005886. eCollection 2016 Sep.

22.

A comparison of PCR assays for beak and feather disease virus and high resolution melt (HRM) curve analysis of replicase associated protein and capsid genes.

Das S, Sarker S, Ghorashi SA, Forwood JK, Raidal SR.

J Virol Methods. 2016 Nov;237:47-57. doi: 10.1016/j.jviromet.2016.08.015. Epub 2016 Aug 23.

PMID:
27565820
23.

Evolution of circoviruses in lorikeets lags behind its hosts.

Das S, Sarker S, Peters A, Ghorashi SA, Phalen D, Forwood JK, Raidal SR.

Mol Phylogenet Evol. 2016 Jul;100:281-291. doi: 10.1016/j.ympev.2016.04.024. Epub 2016 Apr 23.

PMID:
27118178
24.

Characterization of a beta-catenin nuclear localization defect in MCF-7 breast cancer cells.

Jamieson C, Mills KM, Lui C, Semaan C, Molloy MP, Sharma M, Forwood JK, Henderson BR.

Exp Cell Res. 2016 Feb 15;341(2):196-206. doi: 10.1016/j.yexcr.2016.01.020. Epub 2016 Feb 1.

PMID:
26844628
25.

Beak and feather disease virus genotypes in Australian parrots reveal flexible host-switching.

Sarker S, Forwood JK, Ghorashi SA, Peters A, Raidal SR.

Aust Vet J. 2015 Dec;93(12):471-5. doi: 10.1111/avj.12389.

PMID:
26769073
26.

Structural Characterisation of FabG from Yersinia pestis, a Key Component of Bacterial Fatty Acid Synthesis.

Nanson JD, Forwood JK.

PLoS One. 2015 Nov 5;10(11):e0141543. doi: 10.1371/journal.pone.0141543. eCollection 2015.

27.

Structural and Functional Characterization of the PaaI Thioesterase from Streptococcus pneumoniae Reveals a Dual Specificity for Phenylacetyl-CoA and Medium-chain Fatty Acyl-CoAs and a Novel CoA-induced Fit Mechanism.

Khandokar YB, Srivastava P, Sarker S, Swarbrick CM, Aragao D, Cowieson N, Forwood JK.

J Biol Chem. 2016 Jan 22;291(4):1866-76. doi: 10.1074/jbc.M115.677484. Epub 2015 Nov 4.

28.

Structural Biology and Regulation of Protein Import into the Nucleus.

Christie M, Chang CW, Róna G, Smith KM, Stewart AG, Takeda AA, Fontes MR, Stewart M, Vértessy BG, Forwood JK, Kobe B.

J Mol Biol. 2016 May 22;428(10 Pt A):2060-90. doi: 10.1016/j.jmb.2015.10.023. Epub 2015 Oct 30. Review.

PMID:
26523678
29.

Structural Characterisation of the Beta-Ketoacyl-Acyl Carrier Protein Synthases, FabF and FabH, of Yersinia pestis.

Nanson JD, Himiari Z, Swarbrick CM, Forwood JK.

Sci Rep. 2015 Oct 15;5:14797. doi: 10.1038/srep14797.

30.

Evidence of a deep viral host switch event with beak and feather disease virus infection in rainbow bee-eaters (Merops ornatus).

Sarker S, Moylan KG, Ghorashi SA, Forwood JK, Peters A, Raidal SR.

Sci Rep. 2015 Sep 28;5:14511. doi: 10.1038/srep14511.

31.

Structural and functional characterization of TesB from Yersinia pestis reveals a unique octameric arrangement of hotdog domains.

Swarbrick CM, Perugini MA, Cowieson N, Forwood JK.

Acta Crystallogr D Biol Crystallogr. 2015 Apr;71(Pt 4):986-95. doi: 10.1107/S1399004715002527. Epub 2015 Mar 27.

32.

An efficient approach for recombinant expression and purification of the viral capsid protein from beak and feather disease virus (BFDV) in Escherichia coli.

Sarker S, Ghorashi SA, Swarbrick CM, Khandokar YB, Himiari Z, Forwood JK, Raidal SR.

J Virol Methods. 2015 Apr;215-216:1-8. doi: 10.1016/j.jviromet.2015.02.005. Epub 2015 Feb 16.

PMID:
25698466
33.

Erratum for Sarker et al., Molecular Characterization of Genome Sequences of Beak and Feather Disease Virus from the Australian Twenty-Eight Parrot (Barnardius zonarius semitorquatus).

Sarker S, Das S, Ghorashi SA, Forwood JK, Raidal SR.

Genome Announc. 2015 Jan 22;3(1). pii: e01546-14. doi: 10.1128/genomeA.01546-14. No abstract available.

34.

The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replication.

Tay MY, Saw WG, Zhao Y, Chan KW, Singh D, Chong Y, Forwood JK, Ooi EE, Grüber G, Lescar J, Luo D, Vasudevan SG.

J Biol Chem. 2015 Jan 23;290(4):2379-94. doi: 10.1074/jbc.M114.607341. Epub 2014 Dec 8.

35.

Molecular Characterization of Genome Sequences of Beak and Feather Disease Virus from the Australian Twenty-Eight Parrot (Barnardius zonarius semitorquatus).

Sarker S, Das S, Ghorashi SA, Forwood JK, Raidal SR.

Genome Announc. 2014 Dec 4;2(6). pii: e01255-14. doi: 10.1128/genomeA.01255-14. Erratum in: Genome Announc. 2015 Jan 22;3(1):.

36.

Structural characterization of a Gcn5-related N-acetyltransferase from Staphylococcus aureus.

Srivastava P, Khandokar YB, Swarbrick CM, Roman N, Himiari Z, Sarker S, Raidal SR, Forwood JK.

PLoS One. 2014 Aug 13;9(8):e102348. doi: 10.1371/journal.pone.0102348. eCollection 2014.

37.

Rapid genotyping of beak and feather disease virus using high-resolution DNA melt curve analysis.

Sarker S, Ghorashi SA, Forwood JK, Raidal SR.

J Virol Methods. 2014 Nov;208:47-55. doi: 10.1016/j.jviromet.2014.07.031. Epub 2014 Aug 4.

PMID:
25102431
38.

Characterization of the Whole-Genome Sequence of a Beak and Feather Disease Virus Isolate from a Mallee Ringneck Parrot (Barnardius zonarius barnardi).

Das S, Sarker S, Forwood JK, Ghorashi SA, Raidal SR.

Genome Announc. 2014 Jul 24;2(4). pii: e00708-14. doi: 10.1128/genomeA.00708-14.

39.

Phylogeny of beak and feather disease virus in cockatoos demonstrates host generalism and multiple-variant infections within Psittaciformes.

Sarker S, Ghorashi SA, Forwood JK, Bent SJ, Peters A, Raidal SR.

Virology. 2014 Jul;460-461:72-82. doi: 10.1016/j.virol.2014.04.021. Epub 2014 May 29.

40.

Structural basis for regulation of the human acetyl-CoA thioesterase 12 and interactions with the steroidogenic acute regulatory protein-related lipid transfer (START) domain.

Swarbrick CM, Roman N, Cowieson N, Patterson EI, Nanson J, Siponen MI, Berglund H, Lehtiö L, Forwood JK.

J Biol Chem. 2014 Aug 29;289(35):24263-74. doi: 10.1074/jbc.M114.589408. Epub 2014 Jul 7.

41.

Functional disruption of yeast metacaspase, Mca1, leads to miltefosine resistance and inability to mediate miltefosine-induced apoptotic effects.

Biswas C, Zuo X, Chen SC, Schibeci SD, Forwood JK, Jolliffe KA, Sorrell TC, Djordjevic JT.

Fungal Genet Biol. 2014 Jun;67:71-81. doi: 10.1016/j.fgb.2014.04.003. Epub 2014 Apr 13.

PMID:
24731805
42.

Expression, purification, crystallization and preliminary X-ray analysis of the PaaI-like thioesterase SAV0944 from Staphylococcus aureus.

Khandokar YB, Roman N, Smith KM, Srivastava P, Forwood JK.

Acta Crystallogr F Struct Biol Commun. 2014 Feb;70(Pt 2):244-7. doi: 10.1107/S2053230X14000338. Epub 2014 Jan 22.

43.

Purification, crystallization and preliminary X-ray diffraction analysis of the N-acetyltransferase SAV0826 from Staphylococcus aureus.

Srivastava P, Khandokar YB, Forwood JK.

Acta Crystallogr F Struct Biol Commun. 2014 Feb;70(Pt 2):211-4. doi: 10.1107/S2053230X13034493. Epub 2014 Jan 21.

44.

Whole-Genome Sequence Characterization of a Beak and Feather Disease Virus in a Wild Regent Parrot (Polytelis anthopeplus monarchoides).

Sarker S, Forwood JK, Ghorashi SA, McLelland D, Peters A, Raidal SR.

Genome Announc. 2014 Jan 30;2(1). pii: e01243-13. doi: 10.1128/genomeA.01243-13.

45.

Crystallization and preliminary X-ray diffraction analysis of FabG from Yersinia pestis.

Nanson JD, Forwood JK.

Acta Crystallogr F Struct Biol Commun. 2014 Jan;70(Pt 1):101-4. doi: 10.1107/S2053230X13033402. Epub 2013 Dec 24.

46.

Mutability dynamics of an emergent single stranded DNA virus in a naïve host.

Sarker S, Patterson EI, Peters A, Baker GB, Forwood JK, Ghorashi SA, Holdsworth M, Baker R, Murray N, Raidal SR.

PLoS One. 2014 Jan 8;9(1):e85370. doi: 10.1371/journal.pone.0085370. eCollection 2014.

47.

Structural characterisation of the nuclear import receptor importin alpha in complex with the bipartite NLS of Prp20.

Roman N, Christie M, Swarbrick CM, Kobe B, Forwood JK.

PLoS One. 2013 Dec 10;8(12):e82038. doi: 10.1371/journal.pone.0082038. eCollection 2013.

48.

Characterization of the Complete Genome Sequence of a Beak and Feather Disease Virus from a Moluccan Red Lory (Eos bornea).

Sarker S, Ghorashi SA, Forwood JK, Metz S, Raidal SR.

Genome Announc. 2013 Nov 27;1(6). pii: e00844-13. doi: 10.1128/genomeA.00844-13.

49.

Whole-Genome Sequences of Two Beak and Feather Disease Viruses in the Endangered Swift Parrot (Lathamus discolor).

Sarker S, Ghorashi SA, Forwood JK, Raidal SR.

Genome Announc. 2013 Nov 27;1(6). pii: e00842-13. doi: 10.1128/genomeA.00842-13.

50.

Expression, purification and crystallization of acetyl-CoA hydrolase from Neisseria meningitidis.

Khandokar YB, Londhe A, Patil S, Forwood JK.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Nov;69(Pt 11):1303-6. doi: 10.1107/S1744309113028042. Epub 2013 Oct 30.

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