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Items: 1 to 50 of 396

1.

Coordinated program between primary care and sleep unit for the management of obstructive sleep apnea.

Mayos M, Peñacoba P, Pijoan AMP, Santiveri C, Flor X, Juvanteny J, Sampol G, Lloberes P, Aoiz JI, Bayó J, Grau N, Fortuna AM, Plaza V, Llauger MA.

NPJ Prim Care Respir Med. 2019 Nov 8;29(1):39. doi: 10.1038/s41533-019-0151-9.

PMID:
31704942
2.

Sugar-Lowering Drugs for Type 2 Diabetes Mellitus and Metabolic Syndrome-Review of Classical and New Compounds: Part-I.

Vieira R, Souto SB, Sánchez-López E, Machado AL, Severino P, Jose S, Santini A, Fortuna A, García ML, Silva AM, Souto EB.

Pharmaceuticals (Basel). 2019 Oct 10;12(4). pii: E152. doi: 10.3390/ph12040152. Review.

3.

Assessing small airways dysfunction in asthma, asthma remission and healthy controls using particles in exhaled air.

Carpaij OA, Muiser S, Bell AJ, Kerstjens HAM, Galban CJ, Fortuna AB, Siddiqui S, Olin AC, Nawijn MC, van den Berge M.

ERJ Open Res. 2019 Oct 21;5(4). pii: 00202-2019. doi: 10.1183/23120541.00202-2019. eCollection 2019 Oct.

4.

Potential Ad Hoc Markers of Persistence and Virulence in Canadian Listeria monocytogenes Food and Clinical Isolates.

Upham J, Chen S, Boutilier E, Hodges L, Eisebraun M, Croxen MA, Fortuna A, Mallo GV, Garduño RA.

J Food Prot. 2019 Nov;82(11):1909-1921. doi: 10.4315/0362-028X.JFP-19-028.

PMID:
31633427
5.

Impact of direct oral anticoagulants off-label doses on clinical outcomes of atrial fibrillation patients: a systematic review.

Santos J, António N, Rocha M, Fortuna A.

Br J Clin Pharmacol. 2019 Oct 20. doi: 10.1111/bcp.14127. [Epub ahead of print] Review.

PMID:
31631392
6.

Sugar-Lowering Drugs for Type 2 Diabetes Mellitus and Metabolic Syndrome-Strategies for In Vivo Administration: Part-II.

Vieira R, Souto SB, Sánchez-López E, Machado AL, Severino P, Jose S, Santini A, Silva AM, Fortuna A, García ML, Souto EB.

J Clin Med. 2019 Aug 28;8(9). pii: E1332. doi: 10.3390/jcm8091332. Review.

7.

Subtelomeric Rearrangements: Presentation of 21 Probands with Emphasis on Familial Cases.

Soares AR, Soares G, Mota-Freitas M, Oliva-Teles N, Fortuna AM.

Acta Med Port. 2019 Aug 1;32(7-8):529-535. doi: 10.20344/amp.11466. Epub 2019 Aug 1.

8.

Safety and efficacy of edaravone compared to historical controls in patients with amyotrophic lateral sclerosis from North-Eastern Italy.

Fortuna A, Gizzi M, Bello L, Martinelli I, Bertolin C, Pegoraro E, Corbetta M, Sorarù G; Edaravone Study Group.

J Neurol Sci. 2019 Sep 15;404:47-51. doi: 10.1016/j.jns.2019.06.006. Epub 2019 Jun 6.

PMID:
31325668
9.

Comparison of ELISA and HPLC-MS methods for the determination of exenatide in biological and biotechnology-based formulation matrices.

Pinho AR, Fortuna A, Falcão A, Santos AC, Seiça R, Estevens C, Veiga F, Ribeiro AJ.

J Pharm Anal. 2019 Jun;9(3):143-155. doi: 10.1016/j.jpha.2019.02.001. Epub 2019 Feb 26. Review.

10.

Novel bioanalytical method for the quantification of rufinamide in mouse plasma and tissues using HPLC-UV: A tool to support pharmacokinetic studies.

Meirinho S, Rodrigues M, Fortuna A, Falcão A, Alves G.

J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Aug 15;1124:340-348. doi: 10.1016/j.jchromb.2019.06.021. Epub 2019 Jun 19.

PMID:
31279290
11.

Genomic imbalances defining novel intellectual disability associated loci.

Lopes F, Torres F, Soares G, Barbosa M, Silva J, Duque F, Rocha M, Sá J, Oliveira G, Sá MJ, Temudo T, Sousa S, Marques C, Lopes S, Gomes C, Barros G, Jorge A, Rocha F, Martins C, Mesquita S, Loureiro S, Cardoso EM, Cálix MJ, Dias A, Martins C, Mota CR, Antunes D, Dupont J, Figueiredo S, Figueiroa S, Gama-de-Sousa S, Cruz S, Sampaio A, Eijk P, Weiss MM, Ylstra B, Rendeiro P, Tavares P, Reis-Lima M, Pinto-Basto J, Fortuna AM, Maciel P.

Orphanet J Rare Dis. 2019 Jul 5;14(1):164. doi: 10.1186/s13023-019-1135-0.

12.

Development and full validation of an HPLC methodology to quantify atorvastatin and curcumin after their intranasal co-delivery to mice.

Silva J, Basso J, Sousa J, Fortuna A, Vitorino C.

Biomed Chromatogr. 2019 Oct;33(10):e4621. doi: 10.1002/bmc.4621. Epub 2019 Jul 3.

PMID:
31215044
13.

Liquid chromatographic methods for the determination of direct oral anticoagulant drugs in biological samples: A critical review.

Gouveia F, Bicker J, Gonçalves J, Alves G, Falcão A, Fortuna A.

Anal Chim Acta. 2019 Oct 17;1076:18-31. doi: 10.1016/j.aca.2019.03.061. Epub 2019 Apr 8. Review.

PMID:
31203961
14.

Adaption of microarray primers for iron transport and homeostasis gene expression in Pseudomonas fluorescens exposed to nano iron.

Fortuna AM, Sinha S, Das TK, Bezbaruah AN.

MethodsX. 2019 Apr 30;6:1181-1187. doi: 10.1016/j.mex.2019.04.006. eCollection 2019.

15.

Antidepressants and nose-to-brain delivery: drivers, restraints, opportunities and challenges.

Vitorino C, Silva S, Bicker J, Falcão A, Fortuna A.

Drug Discov Today. 2019 Sep;24(9):1911-1923. doi: 10.1016/j.drudis.2019.06.001. Epub 2019 Jun 7. Review.

PMID:
31181188
16.

Understanding gaseous reduction in swine manure resulting from nanoparticle treatments under anaerobic storage conditions.

Sarker NC, Borhan M, Fortuna AM, Rahman S.

J Environ Sci (China). 2019 Aug;82:179-191. doi: 10.1016/j.jes.2019.03.005. Epub 2019 Mar 18.

PMID:
31133263
17.

Eye Drop Instillation of the Rac1 Modulator CNF1 Attenuates Retinal Gliosis and Ameliorates Visual Performance in a Rat Model of Hypertensive Retinopathy.

Matteucci A, Ricceri L, Fabbri A, Fortuna A, Travaglione S, Guidotti M, Martinelli A, Villa M, Pricci F, Maroccia Z, Campana G, Malchiodi-Albedi F, Fiorentini C, Loizzo S.

Neuroscience. 2019 Jul 15;411:119-129. doi: 10.1016/j.neuroscience.2019.05.021. Epub 2019 May 23.

PMID:
31128161
18.

Real-world clinical characterization of subjects with depression treated with antidepressant drugs focused on (non-)genetic factors, pharmacokinetics, and clinical outcomes: GnG-PK/PD-AD study.

Magalhães P, Alves G, Fortuna A, Llerena A, Falcão A.

Exp Clin Psychopharmacol. 2019 May 23. doi: 10.1037/pha0000294. [Epub ahead of print]

PMID:
31120287
19.

ABC transporters in drug-resistant epilepsy: mechanisms of upregulation and therapeutic approaches.

Leandro K, Bicker J, Alves G, Falcão A, Fortuna A.

Pharmacol Res. 2019 Jun;144:357-376. doi: 10.1016/j.phrs.2019.04.031. Epub 2019 Apr 30. Review.

PMID:
31051235
20.

Silymarin as a flavonoid-type P-glycoprotein inhibitor with impact on the pharmacokinetics of carbamazepine, oxcarbazepine and phenytoin in rats.

Ferreira A, Rodrigues M, Meirinho S, Fortuna A, Falcão A, Alves G.

Drug Chem Toxicol. 2019 Apr 25:1-12. doi: 10.1080/01480545.2019.1601736. [Epub ahead of print]

PMID:
31020859
21.

Nose-to-brain delivery of levetiracetam after intranasal administration to mice.

Gonçalves J, Bicker J, Gouveia F, Liberal J, Oliveira RC, Alves G, Falcão A, Fortuna A.

Int J Pharm. 2019 Jun 10;564:329-339. doi: 10.1016/j.ijpharm.2019.04.047. Epub 2019 Apr 20.

PMID:
31015006
22.

First-time oral administration of resveratrol-loaded layer-by-layer nanoparticles to rats - a pharmacokinetics study.

Santos AC, Veiga FJ, Sequeira JAD, Fortuna A, Falcão A, Pereira I, Pattekari P, Fontes-Ribeiro C, Ribeiro AJ.

Analyst. 2019 Mar 21;144(6):2062-2079. doi: 10.1039/c8an01998c. Epub 2019 Feb 6.

PMID:
30724915
23.

Characterization of the microvascular cerebral blood flow response to obstructive apneic events during night sleep.

Zirak P, Gregori-Pla C, Blanco I, Fortuna A, Cotta G, Bramon P, Serra I, Mola A, Solà-Soler J, Giraldo-Giraldo BF, Durduran T, Mayos M.

Neurophotonics. 2018 Oct;5(4):045003. doi: 10.1117/1.NPh.5.4.045003. Epub 2018 Nov 3.

24.

Influence of Inspiratory/Expiratory CT Registration on Quantitative Air Trapping.

Weinheimer O, Hoff BA, Fortuna AB, Fernández-Baldera A, Konietzke P, Wielpütz MO, Robinson TE, Galbán CJ.

Acad Radiol. 2019 Sep;26(9):1202-1214. doi: 10.1016/j.acra.2018.11.001. Epub 2018 Dec 10.

PMID:
30545681
25.

Rethinking carbamazepine oral delivery using polymer-lipid hybrid nanoparticles.

Ana R, Mendes M, Sousa J, Pais A, Falcão A, Fortuna A, Vitorino C.

Int J Pharm. 2019 Jan 10;554:352-365. doi: 10.1016/j.ijpharm.2018.11.028. Epub 2018 Nov 12.

PMID:
30439493
26.

Prevalence of Sleep Disorders in Adults With Down Syndrome: A Comparative Study of Self-Reported, Actigraphic, and Polysomnographic Findings.

Giménez S, Videla L, Romero S, Benejam B, Clos S, Fernández S, Martínez M, Carmona-Iragui M, Antonijoan RM, Mayos M, Fortuna A, Peñacoba P, Plaza V, Osorio RS, Sharma RA, Bardés I, Rebillat AS, Lleó A, Blesa R, Videla S, Fortea J.

J Clin Sleep Med. 2018 Oct 15;14(10):1725-1733. doi: 10.5664/jcsm.7382.

27.

In vitro and in vivo experimental models employed in the discovery and development of antiepileptic drugs for pharmacoresistant epilepsy.

Campos G, Fortuna A, Falcão A, Alves G.

Epilepsy Res. 2018 Oct;146:63-86. doi: 10.1016/j.eplepsyres.2018.07.008. Epub 2018 Jul 21. Review.

PMID:
30086482
28.

Purification of influenza virus-like particles using sulfated cellulose membrane adsorbers.

B Carvalho S, Fortuna AR, Wolff MW, Peixoto C, M Alves P, Reichl U, Jt Carrondo M.

J Chem Technol Biotechnol. 2018 Jul;93(7):1988-1996. doi: 10.1002/jctb.5474. Epub 2017 Dec 16.

29.

Relevance of Breast Cancer Resistance Protein to Brain Distribution and Central Acting Drugs: A Pharmacokinetic Perspective.

Goncalves J, Bicker J, Alves G, Fortuna A, Falcao A.

Curr Drug Metab. 2018;19(12):1021-1041. doi: 10.2174/1389200219666180629121033. Review.

PMID:
29956624
30.

RFT1-CDG: Absence of Epilepsy and Deafness in Two Patients with Novel Pathogenic Variants.

Quelhas D, Jaeken J, Fortuna A, Azevedo L, Bandeira A, Matthijs G, Martins E.

JIMD Rep. 2019;43:111-116. doi: 10.1007/8904_2018_112. Epub 2018 Jun 20.

31.

Draft Genome Sequences of Four Clinical Legionella pneumophila Isolates from Ontario, Canada.

Fortuna A, Ramnarine R, Li A, Fittipaldi N, Frantz C, Mallo GV.

Genome Announc. 2018 Apr 12;6(15). pii: e00295-18. doi: 10.1128/genomeA.00295-18.

32.

Development and full validation of an innovative HPLC-diode array detection technique to simultaneously quantify lacosamide, levetiracetam and zonisamide in human plasma.

Gonçalves J, Alves G, Bicker J, Falcão A, Fortuna A.

Bioanalysis. 2018 Apr 1;10(8):541-557. doi: 10.4155/bio-2017-0199. Epub 2018 Mar 21.

PMID:
29561632
33.

Cerebral vasoreactivity in response to a head-of-bed position change is altered in patients with moderate and severe obstructive sleep apnea.

Gregori-Pla C, Cotta G, Blanco I, Zirak P, Giovannella M, Mola A, Fortuna A, Durduran T, Mayos M.

PLoS One. 2018 Mar 14;13(3):e0194204. doi: 10.1371/journal.pone.0194204. eCollection 2018.

34.

Two Novel Pathogenic MID1 Variants and Genotype-Phenotype Correlation Reanalysis in X-Linked Opitz G/BBB Syndrome.

Maia N, Nabais Sá MJ, Tkachenko N, Soares G, Marques I, Rodrigues B, Fortuna AM, Santos R, de Brouwer APM, Jorge P.

Mol Syndromol. 2017 Dec;9(1):45-51. doi: 10.1159/000479177. Epub 2017 Aug 29.

35.

In vitro assessment of the interactions of dopamine β-hydroxylase inhibitors with human P-glycoprotein and Breast Cancer Resistance Protein.

Bicker J, Alves G, Fortuna A, Soares-da-Silva P, Falcão A.

Eur J Pharm Sci. 2018 May 30;117:35-40. doi: 10.1016/j.ejps.2018.02.006. Epub 2018 Feb 8.

PMID:
29428540
36.

Flavonoid compounds as reversing agents of the P-glycoprotein-mediated multidrug resistance: An in vitro evaluation with focus on antiepileptic drugs.

Ferreira A, Rodrigues M, Fortuna A, Falcão A, Alves G.

Food Res Int. 2018 Jan;103:110-120. doi: 10.1016/j.foodres.2017.10.010. Epub 2017 Oct 12.

PMID:
29389596
37.

The contribution of 7q33 copy number variations for intellectual disability.

Lopes F, Torres F, Lynch SA, Jorge A, Sousa S, Silva J, Rendeiro P, Tavares P, Fortuna AM, Maciel P.

Neurogenetics. 2018 Jan;19(1):27-40. doi: 10.1007/s10048-017-0533-5. Epub 2017 Dec 19.

PMID:
29260337
38.

Elucidation of the Impact of P-glycoprotein and Breast Cancer Resistance Protein on the Brain Distribution of Catechol-O-Methyltransferase Inhibitors.

Bicker J, Fortuna A, Alves G, Soares-da-Silva P, Falcão A.

Drug Metab Dispos. 2017 Dec;45(12):1282-1291. doi: 10.1124/dmd.117.077883. Epub 2017 Sep 15.

PMID:
28916530
39.

Screening of pharmacokinetic properties of fifty dihydropyrimidin(thi)one derivatives using a combo of in vitro and in silico assays.

Matias M, Fortuna A, Bicker J, Silvestre S, Falcão A, Alves G.

Eur J Pharm Sci. 2017 Nov 15;109:334-346. doi: 10.1016/j.ejps.2017.08.023. Epub 2017 Aug 24.

PMID:
28842351
40.

Intranasal Delivery of Topically-Acting Levofloxacin to Rats: a Proof-of-Concept Pharmacokinetic Study.

Sousa J, Alves G, Fortuna A, Falcão A.

Pharm Res. 2017 Nov;34(11):2260-2269. doi: 10.1007/s11095-017-2232-1. Epub 2017 Jul 26.

PMID:
28748398
41.

A single- and multiple-dose study to investigate the pharmacokinetics and pharmacodynamics of opicapone, a novel COMT inhibitor, in rat.

Gonçalves D, Alves G, Fortuna A, Bonifácio MJ, Soares-da-Silva P, Falcão A.

Neuropharmacology. 2017 Oct;125:146-155. doi: 10.1016/j.neuropharm.2017.07.019. Epub 2017 Jul 19.

PMID:
28734868
42.

A randomized controlled trial: branched-chain amino acid levels and glucose metabolism in patients with obesity and sleep apnea.

Barceló A, Morell-Garcia D, Salord N, Esquinas C, Pérez G, Pérez A, Monasterio C, Gasa M, Fortuna AM, Montserrat JM, Mayos M.

J Sleep Res. 2017 Dec;26(6):773-781. doi: 10.1111/jsr.12551. Epub 2017 May 17.

43.

Probability Models Based on Soil Properties for Predicting Presence-Absence of Pythium in Soybean Roots.

Zitnick-Anderson KK, Norland JE, Del Río Mendoza LE, Fortuna AM, Nelson BD Jr.

Microb Ecol. 2017 Oct;74(3):550-560. doi: 10.1007/s00248-017-0958-2. Epub 2017 Apr 6.

PMID:
28386770
44.

Quantitative Effects of Biochar Oxidation and Pyrolysis Temperature on the Transport of Pathogenic and Nonpathogenic Escherichia coli in Biochar-Amended Sand Columns.

Suliman W, Harsh JB, Fortuna AM, Garcia-Pérez M, Abu-Lail NI.

Environ Sci Technol. 2017 May 2;51(9):5071-5081. doi: 10.1021/acs.est.6b04535. Epub 2017 Apr 11.

PMID:
28358986
45.

Pharmacokinetics of opicapone, a third-generation COMT inhibitor, after single and multiple oral administration: A comparative study in the rat.

Gonçalves D, Alves G, Fortuna A, Soares-da-Silva P, Falcão A.

Toxicol Appl Pharmacol. 2017 May 15;323:9-15. doi: 10.1016/j.taap.2017.03.013. Epub 2017 Mar 16.

PMID:
28322896
46.

Determination of catecholamines and endogenous related compounds in rat brain tissue exploring their native fluorescence and liquid chromatography.

Fonseca BM, Rodrigues M, Cristóvão AC, Gonçalves D, Fortuna A, Bernardino L, Falcão A, Alves G.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Apr 1;1049-1050:51-59. doi: 10.1016/j.jchromb.2017.02.028. Epub 2017 Feb 27.

PMID:
28273522
47.

Intranasal delivery of ciprofloxacin to rats: A topical approach using a thermoreversible in situ gel.

Sousa J, Alves G, Oliveira P, Fortuna A, Falcão A.

Eur J Pharm Sci. 2017 Jan 15;97:30-37. doi: 10.1016/j.ejps.2016.10.033. Epub 2016 Nov 1.

PMID:
27810560
48.

The role of biochar porosity and surface functionality in augmenting hydrologic properties of a sandy soil.

Suliman W, Harsh JB, Abu-Lail NI, Fortuna AM, Dallmeyer I, Garcia-Pérez M.

Sci Total Environ. 2017 Jan 1;574:139-147. doi: 10.1016/j.scitotenv.2016.09.025. Epub 2016 Sep 12.

PMID:
27627689
49.

Characterization of zinc oxide nanoparticle (nZnO) alginate beads in reducing gaseous emission from swine manure.

Gautam DP, Rahman S, Fortuna AM, Borhan MS, Saini-Eidukat B, Bezbaruah AN.

Environ Technol. 2017 May;38(9):1061-1074. doi: 10.1080/09593330.2016.1217056. Epub 2016 Aug 11.

PMID:
27457209
50.

P-glycoprotein Mediated Efflux Modulators of Plant Origin: A Short Review.

Silva N, Salgueiro L, Fortuna A, Cavaleiro C.

Nat Prod Commun. 2016 May;11(5):699-704. Review.

PMID:
27319155

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