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Items: 12


Epigenomics and Single-cell Sequencing Define a Developmental Hierarchy in Langerhans Cell Histiocytosis.

Halbritter F, Farlik M, Schwentner R, Jug G, Fortelny N, Schnoller T, Pisa H, Schuster LC, Reinprecht A, Czech T, Gojo J, Holter W, Minkov M, Bauer WM, Simonitsch-Klupp I, Bock C, Hutter C.

Cancer Discov. 2019 Jul 25. pii: CD-19-0138. doi: 10.1158/2159-8290.CD-19-0138. [Epub ahead of print]


The DNA methylation landscape of glioblastoma disease progression shows extensive heterogeneity in time and space.

Klughammer J, Kiesel B, Roetzer T, Fortelny N, Nemc A, Nenning KH, Furtner J, Sheffield NC, Datlinger P, Peter N, Nowosielski M, Augustin M, Mischkulnig M, Ströbel T, Alpar D, Ergüner B, Senekowitsch M, Moser P, Freyschlag CF, Kerschbaumer J, Thomé C, Grams AE, Stockhammer G, Kitzwoegerer M, Oberndorfer S, Marhold F, Weis S, Trenkler J, Buchroithner J, Pichler J, Haybaeck J, Krassnig S, Mahdy Ali K, von Campe G, Payer F, Sherif C, Preiser J, Hauser T, Winkler PA, Kleindienst W, Würtz F, Brandner-Kokalj T, Stultschnig M, Schweiger S, Dieckmann K, Preusser M, Langs G, Baumann B, Knosp E, Widhalm G, Marosi C, Hainfellner JA, Woehrer A, Bock C.

Nat Med. 2018 Oct;24(10):1611-1624. doi: 10.1038/s41591-018-0156-x. Epub 2018 Aug 27.


C-terminal truncation of IFN-γ inhibits proinflammatory macrophage responses and is deficient in autoimmune disease.

Dufour A, Bellac CL, Eckhard U, Solis N, Klein T, Kappelhoff R, Fortelny N, Jobin P, Rozmus J, Mark J, Pavlidis P, Dive V, Barbour SJ, Overall CM.

Nat Commun. 2018 Jun 20;9(1):2416. doi: 10.1038/s41467-018-04717-4.


Can we predict protein from mRNA levels?

Fortelny N, Overall CM, Pavlidis P, Freue GVC.

Nature. 2017 Jul 26;547(7664):E19-E20. doi: 10.1038/nature22293. No abstract available.


Protease-Inhibitor Interaction Predictions: Lessons on the Complexity of Protein-Protein Interactions.

Fortelny N, Butler GS, Overall CM, Pavlidis P.

Mol Cell Proteomics. 2017 Jun;16(6):1038-1051. doi: 10.1074/mcp.M116.065706. Epub 2017 Apr 6.


Interactome disassembly during apoptosis occurs independent of caspase cleavage.

Scott NE, Rogers LD, Prudova A, Brown NF, Fortelny N, Overall CM, Foster LJ.

Mol Syst Biol. 2017 Jan 12;13(1):906. doi: 10.15252/msb.20167067.


TAILS N-Terminomics and Proteomics Show Protein Degradation Dominates over Proteolytic Processing by Cathepsins in Pancreatic Tumors.

Prudova A, Gocheva V, Auf dem Keller U, Eckhard U, Olson OC, Akkari L, Butler GS, Fortelny N, Lange PF, Mark JC, Joyce JA, Overall CM.

Cell Rep. 2016 Aug 9;16(6):1762-1773. doi: 10.1016/j.celrep.2016.06.086. Epub 2016 Jul 28.


Uncovering a Dual Regulatory Role for Caspases During Endoplasmic Reticulum Stress-induced Cell Death.

Anania VG, Yu K, Gnad F, Pferdehirt RR, Li H, Ma TP, Jeon D, Fortelny N, Forrest W, Ashkenazi A, Overall CM, Lill JR.

Mol Cell Proteomics. 2016 Jul;15(7):2293-307. doi: 10.1074/mcp.M115.055376. Epub 2016 Apr 28.


The path of no return--Truncated protein N-termini and current ignorance of their genesis.

Fortelny N, Pavlidis P, Overall CM.

Proteomics. 2015 Jul;15(14):2547-52. doi: 10.1002/pmic.201500043. Epub 2015 Jun 15.


Proteome TopFIND 3.0 with TopFINDer and PathFINDer: database and analysis tools for the association of protein termini to pre- and post-translational events.

Fortelny N, Yang S, Pavlidis P, Lange PF, Overall CM.

Nucleic Acids Res. 2015 Jan;43(Database issue):D290-7. doi: 10.1093/nar/gku1012. Epub 2014 Oct 20.


TAILS N-terminomics of human platelets reveals pervasive metalloproteinase-dependent proteolytic processing in storage.

Prudova A, Serrano K, Eckhard U, Fortelny N, Devine DV, Overall CM.

Blood. 2014 Dec 18;124(26):e49-60. doi: 10.1182/blood-2014-04-569640. Epub 2014 Oct 20.


Network analyses reveal pervasive functional regulation between proteases in the human protease web.

Fortelny N, Cox JH, Kappelhoff R, Starr AE, Lange PF, Pavlidis P, Overall CM.

PLoS Biol. 2014 May 27;12(5):e1001869. doi: 10.1371/journal.pbio.1001869. eCollection 2014 May.

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