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Items: 1 to 50 of 73

1.

Abnormal Eating Patterns Cause Circadian Disruption and Promote Alcohol-Associated Colon Carcinogenesis.

Bishehsari F, Engen PA, Voigt RM, Swanson G, Shaikh M, Wilber S, Naqib A, Green SJ, Shetuni B, Forsyth CB, Saadalla A, Osman A, Hamaker BR, Keshavarzian A, Khazaie K.

Cell Mol Gastroenterol Hepatol. 2019 Nov 2. pii: S2352-345X(19)30147-X. doi: 10.1016/j.jcmgh.2019.10.011. [Epub ahead of print]

2.

Alcohol Effects on Colon Epithelium are Time-Dependent.

Bishehsari F, Zhang L, Voigt RM, Maltby N, Semsarieh B, Zorub E, Shaikh M, Wilber S, Armstrong AR, Mirbagheri SS, Preite NZ, Song P, Stornetta A, Balbo S, Forsyth CB, Keshavarzian A.

Alcohol Clin Exp Res. 2019 Sep;43(9):1898-1908. doi: 10.1111/acer.14141. Epub 2019 Jul 22.

PMID:
31237690
3.

Circadian rhythms: a regulator of gastrointestinal health and dysfunction.

Voigt RM, Forsyth CB, Keshavarzian A.

Expert Rev Gastroenterol Hepatol. 2019 May;13(5):411-424. doi: 10.1080/17474124.2019.1595588. Epub 2019 Mar 25.

PMID:
30874451
4.

Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease.

Dodiya HB, Forsyth CB, Voigt RM, Engen PA, Patel J, Shaikh M, Green SJ, Naqib A, Roy A, Kordower JH, Pahan K, Shannon KM, Keshavarzian A.

Neurobiol Dis. 2018 Dec 21:104352. doi: 10.1016/j.nbd.2018.12.012. [Epub ahead of print] Review.

PMID:
30579705
5.

Role of TLR4 in the gut-brain axis in Parkinson's disease: a translational study from men to mice.

Perez-Pardo P, Dodiya HB, Engen PA, Forsyth CB, Huschens AM, Shaikh M, Voigt RM, Naqib A, Green SJ, Kordower JH, Shannon KM, Garssen J, Kraneveld AD, Keshavarzian A.

Gut. 2019 May;68(5):829-843. doi: 10.1136/gutjnl-2018-316844. Epub 2018 Dec 15.

6.

Wnt signaling in bone, kidney, intestine, and adipose tissue and interorgan interaction in aging.

Chen D, Xie R, Shu B, Landay AL, Wei C, Reiser J, Spagnoli A, Torquati A, Forsyth CB, Keshavarzian A, Sumner DR.

Ann N Y Acad Sci. 2019 Apr;1442(1):48-60. doi: 10.1111/nyas.13945. Epub 2018 Aug 12. Review.

PMID:
30101565
7.

Gut bacterial composition in a mouse model of Parkinson's disease.

Perez-Pardo P, Dodiya HB, Engen PA, Naqib A, Forsyth CB, Green SJ, Garssen J, Keshavarzian A, Kraneveld AD.

Benef Microbes. 2018 Sep 18;9(5):799-814. doi: 10.3920/BM2017.0202. Epub 2018 Aug 13.

PMID:
30099890
8.

Corrigendum to "Pharmacological targeting of the mammalian clock reveals a novel analgesic for osteoarthritis-induced pain" [GENE 655 (2018) 1-12].

Das V, Kc R, Li X, Varma D, Qiu S, Kroin JS, Forsyth CB, Keshavarzian A, van Wijnen AJ, Park TJ, Stein GS, O-Sullivan I, Burris TP, Im HJ.

Gene. 2019 Jan 5;680:105. doi: 10.1016/j.gene.2018.06.013. Epub 2018 Jun 12. No abstract available.

PMID:
29890121
9.

Pharmacological targeting of the mammalian clock reveals a novel analgesic for osteoarthritis-induced pain.

Das V, Kc R, Li X, Varma D, Qiu S, Kroin JS, Forsyth CB, Keshavarzian A, van Wijnen AJ, Park TJ, Stein GS, O-Sullivan I, Burris TP, Im HJ.

Gene. 2018 May 20;655:1-12. doi: 10.1016/j.gene.2018.02.048. Epub 2018 Feb 20. Erratum in: Gene. 2019 Jan 5;680:105.

PMID:
29474860
10.

Dietary Fiber Treatment Corrects the Composition of Gut Microbiota, Promotes SCFA Production, and Suppresses Colon Carcinogenesis.

Bishehsari F, Engen PA, Preite NZ, Tuncil YE, Naqib A, Shaikh M, Rossi M, Wilber S, Green SJ, Hamaker BR, Khazaie K, Voigt RM, Forsyth CB, Keshavarzian A.

Genes (Basel). 2018 Feb 16;9(2). pii: E102. doi: 10.3390/genes9020102.

11.

Circadian Mechanisms in Alcohol Use Disorder and Tissue Injury.

Davis BT 4th, Voigt RM, Shaikh M, Forsyth CB, Keshavarzian A.

Alcohol Clin Exp Res. 2018 Apr;42(4):668-677. doi: 10.1111/acer.13612. Epub 2018 Mar 8. Review.

12.

The Foxo1-Inducible Transcriptional Repressor Zfp125 Causes Hepatic Steatosis and Hypercholesterolemia.

Fernandes GW, Bocco BMLC, Fonseca TL, McAninch EA, Jo S, Lartey LJ, O-Sullivan I, Unterman TG, Preite NZ, Voigt RM, Forsyth CB, Keshavarzian A, Sinkó R, Goldfine AB, Patti ME, Ribeiro MO, Gereben B, Bianco AC.

Cell Rep. 2018 Jan 9;22(2):523-534. doi: 10.1016/j.celrep.2017.12.053.

13.

Colon dysregulation in methamphetamine self-administering HIV-1 transgenic rats.

Persons AL, Bradaric BD, Dodiya HB, Ohene-Nyako M, Forsyth CB, Keshavarzian A, Shaikh M, Napier TC.

PLoS One. 2018 Jan 2;13(1):e0190078. doi: 10.1371/journal.pone.0190078. eCollection 2018.

14.

Diurnal variations in intestinal barrier integrity and liver pathology in mice: implications for alcohol binge.

Voigt RM, Forsyth CB, Shaikh M, Zhang L, Raeisi S, Aloman C, Preite NZ, Donohue TM Jr, Fogg L, Keshavarzian A.

Am J Physiol Gastrointest Liver Physiol. 2018 Jan 1;314(1):G131-G141. doi: 10.1152/ajpgi.00103.2017. Epub 2017 Oct 26.

15.

Alcohol Feeding in Mice Promotes Colonic Hyperpermeability and Changes in Colonic Organoid Stem Cell Fate.

Forsyth CB, Shaikh M, Bishehsari F, Swanson G, Voigt RM, Dodiya H, Wilkinson P, Samelco B, Song S, Keshavarzian A.

Alcohol Clin Exp Res. 2017 Dec;41(12):2100-2113. doi: 10.1111/acer.13519. Epub 2017 Nov 7.

16.

Alcohol and Gut-Derived Inflammation.

Bishehsari F, Magno E, Swanson G, Desai V, Voigt RM, Forsyth CB, Keshavarzian A.

Alcohol Res. 2017;38(2):163-171. Review.

17.

CREB Protein Mediates Alcohol-Induced Circadian Disruption and Intestinal Permeability.

Davis BT 4th, Voigt RM, Shaikh M, Forsyth CB, Keshavarzian A.

Alcohol Clin Exp Res. 2017 Dec;41(12):2007-2014. doi: 10.1111/acer.13513. Epub 2017 Oct 30.

18.

The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy.

Engen PA, Dodiya HB, Naqib A, Forsyth CB, Green SJ, Voigt RM, Kordower JH, Mutlu EA, Shannon KM, Keshavarzian A.

J Parkinsons Dis. 2017;7(2):331-346. doi: 10.3233/JPD-160991.

PMID:
28234259
19.

Alcohol Injury Damages Intestinal Stem Cells.

Lu R, Voigt RM, Zhang Y, Kato I, Xia Y, Forsyth CB, Keshavarzian A, Sun J.

Alcohol Clin Exp Res. 2017 Apr;41(4):727-734. doi: 10.1111/acer.13351. Epub 2017 Mar 10.

20.

Circadian Rhythm and the Gut Microbiome.

Voigt RM, Forsyth CB, Green SJ, Engen PA, Keshavarzian A.

Int Rev Neurobiol. 2016;131:193-205. doi: 10.1016/bs.irn.2016.07.002. Epub 2016 Sep 6. Review.

PMID:
27793218
21.

Lower Neighborhood Socioeconomic Status Associated with Reduced Diversity of the Colonic Microbiota in Healthy Adults.

Miller GE, Engen PA, Gillevet PM, Shaikh M, Sikaroodi M, Forsyth CB, Mutlu E, Keshavarzian A.

PLoS One. 2016 Feb 9;11(2):e0148952. doi: 10.1371/journal.pone.0148952. eCollection 2016.

22.

The Circadian Clock Mutation Promotes Intestinal Dysbiosis.

Voigt RM, Summa KC, Forsyth CB, Green SJ, Engen P, Naqib A, Vitaterna MH, Turek FW, Keshavarzian A.

Alcohol Clin Exp Res. 2016 Feb;40(2):335-47. doi: 10.1111/acer.12943.

23.

The Gastrointestinal Microbiome: Alcohol Effects on the Composition of Intestinal Microbiota.

Engen PA, Green SJ, Voigt RM, Forsyth CB, Keshavarzian A.

Alcohol Res. 2015;37(2):223-36. Review.

24.

Osteoarthritis-like pathologic changes in the knee joint induced by environmental disruption of circadian rhythms is potentiated by a high-fat diet.

Kc R, Li X, Forsyth CB, Voigt RM, Summa KC, Vitaterna MH, Tryniszewska B, Keshavarzian A, Turek FW, Meng QJ, Im HJ.

Sci Rep. 2015 Nov 20;5:16896. doi: 10.1038/srep16896.

25.

Alcohol and the Intestine.

Patel S, Behara R, Swanson GR, Forsyth CB, Voigt RM, Keshavarzian A.

Biomolecules. 2015 Oct 15;5(4):2573-88. doi: 10.3390/biom5042573. Review.

26.

Abnormal lipopolysaccharide binding protein as marker of gastrointestinal inflammation in Parkinson disease.

Pal GD, Shaikh M, Forsyth CB, Ouyang B, Keshavarzian A, Shannon KM.

Front Neurosci. 2015 Sep 1;9:306. doi: 10.3389/fnins.2015.00306. eCollection 2015.

27.

Chronic Alcohol Exposure and the Circadian Clock Mutation Exert Tissue-Specific Effects on Gene Expression in Mouse Hippocampus, Liver, and Proximal Colon.

Summa KC, Jiang P, Fitzpatrick K, Voigt RM, Bowers SJ, Forsyth CB, Vitaterna MH, Keshavarzian A, Turek FW.

Alcohol Clin Exp Res. 2015 Oct;39(10):1917-29. doi: 10.1111/acer.12834. Epub 2015 Sep 2.

28.

The Role of miR-212 and iNOS in Alcohol-Induced Intestinal Barrier Dysfunction and Steatohepatitis.

Tang Y, Zhang L, Forsyth CB, Shaikh M, Song S, Keshavarzian A.

Alcohol Clin Exp Res. 2015 Sep;39(9):1632-41. doi: 10.1111/acer.12813. Epub 2015 Jul 24.

29.

Colonic bacterial composition in Parkinson's disease.

Keshavarzian A, Green SJ, Engen PA, Voigt RM, Naqib A, Forsyth CB, Mutlu E, Shannon KM.

Mov Disord. 2015 Sep;30(10):1351-60. doi: 10.1002/mds.26307. Epub 2015 Jul 16.

PMID:
26179554
30.

Alcohol induced alterations to the human fecal VOC metabolome.

Couch RD, Dailey A, Zaidi F, Navarro K, Forsyth CB, Mutlu E, Engen PA, Keshavarzian A.

PLoS One. 2015 Mar 9;10(3):e0119362. doi: 10.1371/journal.pone.0119362. eCollection 2015.

31.

Induction of Osteoarthritis-like Pathologic Changes by Chronic Alcohol Consumption in an Experimental Mouse Model.

Kc R, Voigt R, Li X, Forsyth CB, Ellman MB, Summa KC, Turek FW, Keshavarzian A, Kim JS, Im HJ.

Arthritis Rheumatol. 2015 Jun;67(6):1678-80. doi: 10.1002/art.39090. No abstract available.

32.

Environmental disruption of circadian rhythm predisposes mice to osteoarthritis-like changes in knee joint.

Kc R, Li X, Voigt RM, Ellman MB, Summa KC, Vitaterna MH, Keshavarizian A, Turek FW, Meng QJ, Stein GS, van Wijnen AJ, Chen D, Forsyth CB, Im HJ.

J Cell Physiol. 2015 Sep;230(9):2174-2183. doi: 10.1002/jcp.24946.

33.

Simultaneous gas-chromatographic urinary measurement of sugar probes to assess intestinal permeability: use of time course analysis to optimize its use to assess regional gut permeability.

Shaikh M, Rajan K, Forsyth CB, Voigt RM, Keshavarzian A.

Clin Chim Acta. 2015 Mar 10;442:24-32. doi: 10.1016/j.cca.2014.12.040. Epub 2015 Jan 12.

34.

HIV-associated mucosal gene expression: region-specific alterations.

Voigt RM, Keshavarzian A, Losurdo J, Swanson G, Siewe B, Forsyth CB, French AL, Demarais P, Engen P, Raeisi S, Mutlu E, Landay AL.

AIDS. 2015 Mar 13;29(5):537-46. doi: 10.1097/QAD.0000000000000569.

35.

Circadian rhythms, alcohol and gut interactions.

Forsyth CB, Voigt RM, Burgess HJ, Swanson GR, Keshavarzian A.

Alcohol. 2015 Jun;49(4):389-98. doi: 10.1016/j.alcohol.2014.07.021. Epub 2014 Nov 14. Review.

36.

Intestinal CYP2E1: A mediator of alcohol-induced gut leakiness.

Forsyth CB, Voigt RM, Keshavarzian A.

Redox Biol. 2014;3:40-6. doi: 10.1016/j.redox.2014.10.002. Epub 2014 Oct 19. Review.

37.

The role of miRNAs in alcohol-induced endotoxemia, dysfunction of mucosal immunity, and gut leakiness.

Tang Y, Forsyth CB, Keshavarzian A.

Alcohol Clin Exp Res. 2014 Sep;38(9):2331-4. doi: 10.1111/acer.12551. Review. No abstract available.

PMID:
25257284
38.

In vitro evaluation of intestinal epithelial TLR activation in preventing food allergic responses.

de Kivit S, Tobin MC, DeMeo MT, Fox S, Garssen J, Forsyth CB, Keshavarzian A, Landay AL.

Clin Immunol. 2014 Oct;154(2):91-9. doi: 10.1016/j.clim.2014.07.002. Epub 2014 Jul 21.

PMID:
25058467
39.

Circadian disorganization alters intestinal microbiota.

Voigt RM, Forsyth CB, Green SJ, Mutlu E, Engen P, Vitaterna MH, Turek FW, Keshavarzian A.

PLoS One. 2014 May 21;9(5):e97500. doi: 10.1371/journal.pone.0097500. eCollection 2014.

40.

Regulation of Intestinal Immune Responses through TLR Activation: Implications for Pro- and Prebiotics.

de Kivit S, Tobin MC, Forsyth CB, Keshavarzian A, Landay AL.

Front Immunol. 2014 Feb 18;5:60. doi: 10.3389/fimmu.2014.00060. eCollection 2014. Review.

41.
42.

The approach to sample acquisition and its impact on the derived human fecal microbiome and VOC metabolome.

Couch RD, Navarro K, Sikaroodi M, Gillevet P, Forsyth CB, Mutlu E, Engen PA, Keshavarzian A.

PLoS One. 2013 Nov 18;8(11):e81163. doi: 10.1371/journal.pone.0081163. eCollection 2013.

43.

Disruption of the Circadian Clock in Mice Increases Intestinal Permeability and Promotes Alcohol-Induced Hepatic Pathology and Inflammation.

Summa KC, Voigt RM, Forsyth CB, Shaikh M, Cavanaugh K, Tang Y, Vitaterna MH, Song S, Turek FW, Keshavarzian A.

PLoS One. 2013 Jun 18;8(6):e67102. doi: 10.1371/journal.pone.0067102. Print 2013.

44.

Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability.

Forsyth CB, Voigt RM, Shaikh M, Tang Y, Cederbaum AI, Turek FW, Keshavarzian A.

Am J Physiol Gastrointest Liver Physiol. 2013 Jul 15;305(2):G185-95. doi: 10.1152/ajpgi.00354.2012. Epub 2013 May 9.

45.

Ethanol-induced mast cell-mediated inflammation leads to increased susceptibility of intestinal tumorigenesis in the APC Δ468 min mouse model of colon cancer.

Wimberly AL, Forsyth CB, Khan MW, Pemberton A, Khazaie K, Keshavarzian A.

Alcohol Clin Exp Res. 2013 Jan;37 Suppl 1:E199-208. doi: 10.1111/j.1530-0277.2012.01894.x.

46.

Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease.

Forsyth CB, Shannon KM, Kordower JH, Voigt RM, Shaikh M, Jaglin JA, Estes JD, Dodiya HB, Keshavarzian A.

PLoS One. 2011;6(12):e28032. doi: 10.1371/journal.pone.0028032. Epub 2011 Dec 1.

47.

New molecular insights into inflammatory bowel disease-induced diarrhea.

Tang Y, Forsyth CB, Keshavarzian A.

Expert Rev Gastroenterol Hepatol. 2011 Oct;5(5):615-25. doi: 10.1586/egh.11.64. Review.

48.

Particulate matter air pollution causes oxidant-mediated increase in gut permeability in mice.

Mutlu EA, Engen PA, Soberanes S, Urich D, Forsyth CB, Nigdelioglu R, Chiarella SE, Radigan KA, Gonzalez A, Jakate S, Keshavarzian A, Budinger GR, Mutlu GM.

Part Fibre Toxicol. 2011 Jun 9;8:19. doi: 10.1186/1743-8977-8-19.

49.

Loss of p120 catenin upregulates transcription of pro-inflammatory adhesion molecules in human endothelial cells.

O'Donnell JJ 3rd, Zhuge Y, Holian O, Cheng F, Thomas LL, Forsyth CB, Lum H.

Microvasc Res. 2011 Sep;82(2):105-12. doi: 10.1016/j.mvr.2011.04.008. Epub 2011 Apr 30.

50.

Role of snail activation in alcohol-induced iNOS-mediated disruption of intestinal epithelial cell permeability.

Forsyth CB, Tang Y, Shaikh M, Zhang L, Keshavarzian A.

Alcohol Clin Exp Res. 2011 Sep;35(9):1635-43. doi: 10.1111/j.1530-0277.2011.01510.x. Epub 2011 Apr 27.

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