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Items: 26

1.

Investigating the function and possible biological role of an acetylcholine-gated chloride channel subunit (ACC-1) from the parasitic nematode Haemonchus contortus.

Callanan MK, Habibi SA, Law WJ, Nazareth K, Komuniecki RL, Forrester SG.

Int J Parasitol Drugs Drug Resist. 2018 Oct 27. pii: S2211-3207(18)30107-6. doi: 10.1016/j.ijpddr.2018.10.010. [Epub ahead of print]

2.

A mutational and molecular dynamics study of the cys-loop GABA receptor Hco-UNC-49 from Haemonchus contortus: Agonist recognition in the nematode GABA receptor family.

Foster J, Cochrane E, Khatami MH, Habibi SA, de Haan H, Forrester SG.

Int J Parasitol Drugs Drug Resist. 2018 Oct 6. pii: S2211-3207(18)30105-2. doi: 10.1016/j.ijpddr.2018.10.001. [Epub ahead of print]

3.

Molecular and pharmacological characterization of an acetylcholine-gated chloride channel (ACC-2) from the parasitic nematode Haemonchus contortus.

Habibi SA, Callanan M, Forrester SG.

Int J Parasitol Drugs Drug Resist. 2018 Sep 22. pii: S2211-3207(18)30129-5. doi: 10.1016/j.ijpddr.2018.09.004. [Epub ahead of print]

4.

Molecular Characterization of Binding Loop E in the Nematode Cys-Loop GABA Receptor.

Kwaka A, Hassan Khatami M, Foster J, Cochrane E, Habibi SA, de Haan HW, Forrester SG.

Mol Pharmacol. 2018 Nov;94(5):1289-1297. doi: 10.1124/mol.118.112821. Epub 2018 Sep 7.

PMID:
30194106
5.

Evaluating the longevity of surgically extracted Xenopus laevis oocytes for the study of nematode ligand-gated ion channels.

Abdelmassih SA, Cochrane E, Forrester SG.

Invert Neurosci. 2017 Nov 28;18(1):1. doi: 10.1007/s10158-017-0205-z.

PMID:
29185074
6.

Efficient synthesis of the GABAA receptor agonist trans-4-aminocrotonic acid (TACA).

Forrester SG, Foster J, Robert S, Salim L, Desaulniers JP.

Bioorg Med Chem Lett. 2017 Sep 15;27(18):4512-4513. doi: 10.1016/j.bmcl.2017.07.050. Epub 2017 Jul 20.

PMID:
28838689
7.

Recent Duplication and Functional Divergence in Parasitic Nematode Levamisole-Sensitive Acetylcholine Receptors.

Duguet TB, Charvet CL, Forrester SG, Wever CM, Dent JA, Neveu C, Beech RN.

PLoS Negl Trop Dis. 2016 Jul 14;10(7):e0004826. doi: 10.1371/journal.pntd.0004826. eCollection 2016 Jul.

8.

A molecular characterization of the agonist binding site of a nematode cys-loop GABA receptor.

Kaji MD, Kwaka A, Callanan MK, Nusrat H, Desaulniers JP, Forrester SG.

Br J Pharmacol. 2015 Aug;172(15):3737-47. doi: 10.1111/bph.13158. Epub 2015 May 19.

9.

Characterization of cys-loop receptor genes involved in inhibitory amine neurotransmission in parasitic and free living nematodes.

Beech RN, Callanan MK, Rao VT, Dawe GB, Forrester SG.

Parasitol Int. 2013 Dec;62(6):599-605. doi: 10.1016/j.parint.2013.03.010. Epub 2013 Apr 16.

PMID:
23602737
10.

Hco-LGC-38 is novel nematode cys-loop GABA receptor subunit.

Siddiqui SZ, Brown DD, Accardi MV, Forrester SG.

Mol Biochem Parasitol. 2012 Oct;185(2):137-44. doi: 10.1016/j.molbiopara.2012.08.004. Epub 2012 Aug 23.

PMID:
22940478
11.

Nematode cys-loop GABA receptors: biological function, pharmacology and sites of action for anthelmintics.

Accardi MV, Beech RN, Forrester SG.

Invert Neurosci. 2012 Jun;12(1):3-12. doi: 10.1007/s10158-012-0129-6. Epub 2012 Mar 20. Review.

PMID:
22430311
12.

Pharmacological characterization of the Haemonchus contortus GABA-gated chloride channel, Hco-UNC-49: modulation by macrocyclic lactone anthelmintics and a receptor for piperazine.

Brown DD, Siddiqui SZ, Kaji MD, Forrester SG.

Vet Parasitol. 2012 Apr 30;185(2-4):201-9. doi: 10.1016/j.vetpar.2011.10.006. Epub 2011 Oct 15.

PMID:
22075040
13.

The Haemonchus contortus UNC-49B subunit possesses the residues required for GABA sensitivity in homomeric and heteromeric channels.

Accardi MV, Forrester SG.

Mol Biochem Parasitol. 2011 Jul-Aug;178(1-2):15-22. doi: 10.1016/j.molbiopara.2011.04.002. Epub 2011 Apr 16.

PMID:
21524670
14.

Localisation of serotonin and dopamine in Haemonchus contortus.

Rao VT, Forrester SG, Keller K, Prichard RK.

Int J Parasitol. 2011 Feb;41(2):249-54. doi: 10.1016/j.ijpara.2010.09.002. Epub 2010 Sep 29.

PMID:
20887725
15.

Characterization of a novel tyramine-gated chloride channel from Haemonchus contortus.

Rao VT, Accardi MV, Siddiqui SZ, Beech RN, Prichard RK, Forrester SG.

Mol Biochem Parasitol. 2010 Oct;173(2):64-8. doi: 10.1016/j.molbiopara.2010.05.005. Epub 2010 May 13.

PMID:
20471431
16.

Association of ion-channel genotype and macrocyclic lactone sensitivity traits in Haemonchus contortus.

Beech R, Levitt N, Cambos M, Zhou S, Forrester SG.

Mol Biochem Parasitol. 2010 Jun;171(2):74-80. doi: 10.1016/j.molbiopara.2010.02.004. Epub 2010 Mar 6.

PMID:
20211658
17.

An UNC-49 GABA receptor subunit from the parasitic nematode Haemonchus contortus is associated with enhanced GABA sensitivity in nematode heteromeric channels.

Siddiqui SZ, Brown DD, Rao VT, Forrester SG.

J Neurochem. 2010 Jun;113(5):1113-22. doi: 10.1111/j.1471-4159.2010.06651.x. Epub 2010 Feb 23.

18.

A dopamine-gated ion channel (HcGGR3*) from Haemonchus contortus is expressed in the cervical papillae and is associated with macrocyclic lactone resistance.

Rao VT, Siddiqui SZ, Prichard RK, Forrester SG.

Mol Biochem Parasitol. 2009 Jul;166(1):54-61. doi: 10.1016/j.molbiopara.2009.02.011. Epub 2009 Mar 4.

PMID:
19428673
19.

A novel member of the ligand-gated chloride channel gene family from Haemonchus contortus.

Forrester SG, Siddiqui SZ.

Parasitology. 2008 Apr;135(4):539-45. Epub 2007 Dec 20.

PMID:
18093350
20.

Tegumental expression of a novel type II receptor serine/threonine kinase (SmRK2) in Schistosoma mansoni.

Forrester SG, Warfel PW, Pearce EJ.

Mol Biochem Parasitol. 2004 Aug;136(2):149-56.

PMID:
15478794
21.

Agonist enhacement of macrocyclic lactone activity at a glutamate-gated chloride channel subunit from Haemonchus contortus.

Forrester SG, Beech RN, Prichard RK.

Biochem Pharmacol. 2004 Mar 15;67(6):1019-24.

PMID:
15006538
22.
24.

Cloning, sequencing, and developmental expression levels of a novel glutamate-gated chloride channel homologue in the parasitic nematode Haemonchus contortus.

Forrester SG, Hamdan FF, Prichard RK, Beech RN.

Biochem Biophys Res Commun. 1999 Jan 27;254(3):529-34.

PMID:
9920773
25.

Extracting Protostrongylus spp. larvae from bighorn sheep feces.

Forrester SG, Lankester MW.

J Wildl Dis. 1997 Oct;33(4):868-72.

PMID:
9391973
26.

Extracting protostrongylid nematode larvae from ungulate feces.

Forrester SG, Lankester MW.

J Wildl Dis. 1997 Jul;33(3):511-6.

PMID:
9249697

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