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Items: 30

1.

Gene Expression in Mammalian Cells Using BacMam, a Modified Baculovirus System.

Fornwald JA, Lu Q, Boyce FM, Ames RS.

Methods Mol Biol. 2016;1350:95-116. doi: 10.1007/978-1-4939-3043-2_5.

PMID:
26820855
2.

High throughput screening identifies ATP-competitive inhibitors of the NLRP1 inflammasome.

Harris PA, Duraiswami C, Fisher DT, Fornwald J, Hoffman SJ, Hofmann G, Jiang M, Lehr R, McCormick PM, Nickels L, Schwartz B, Wu Z, Zhang G, Marquis RW, Bertin J, Gough PJ.

Bioorg Med Chem Lett. 2015 Jul 15;25(14):2739-43. doi: 10.1016/j.bmcl.2015.05.032. Epub 2015 May 19.

PMID:
26022841
3.

Identification and characterization of PERK activators by phenotypic screening and their effects on NRF2 activation.

Xie W, Pariollaud M, Wixted WE, Chitnis N, Fornwald J, Truong M, Pao C, Liu Y, Ames RS, Callahan J, Solari R, Sanchez Y, Diehl A, Li H.

PLoS One. 2015 Mar 17;10(3):e0119738. doi: 10.1371/journal.pone.0119738. eCollection 2015.

4.

Optimized procedures for producing biologically active chemokines.

Lu Q, Burns MC, McDevitt PJ, Graham TL, Sukman AJ, Fornwald JA, Tang X, Gallagher KT, Hunsberger GE, Foley JJ, Schmidt DB, Kerrigan JJ, Lewis TS, Ames RS, Johanson KO.

Protein Expr Purif. 2009 Jun;65(2):251-60.

PMID:
19297698
5.

Rapid expression of recombinant proteins in modified CHO cells using the baculovirus system.

Ramos L, Kopec LA, Sweitzer SM, Fornwald JA, Zhao H, McAllister P, McNulty DE, Trill JJ, Kane JF.

Cytotechnology. 2002 Jan;38(1-3):37-41. doi: 10.1023/A:1021189628274.

6.

Gene expression in mammalian cells using BacMam, a modified baculovirus system.

Fornwald JA, Lu Q, Wang D, Ames RS.

Methods Mol Biol. 2007;388:95-114.

PMID:
17951767
7.

Oxazolidinones as novel human CCR8 antagonists.

Jin J, Wang Y, Wang F, Kerns JK, Vinader VM, Hancock AP, Lindon MJ, Stevenson GI, Morrow DM, Rao P, Nguyen C, Barrett VJ, Browning C, Hartmann G, Andrew DP, Sarau HM, Foley JJ, Jurewicz AJ, Fornwald JA, Harker AJ, Moore ML, Rivero RA, Belmonte KE, Connor HE.

Bioorg Med Chem Lett. 2007 Mar 15;17(6):1722-5. Epub 2006 Dec 24.

PMID:
17267215
8.

Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules.

Briscoe CP, Peat AJ, McKeown SC, Corbett DF, Goetz AS, Littleton TR, McCoy DC, Kenakin TP, Andrews JL, Ammala C, Fornwald JA, Ignar DM, Jenkinson S.

Br J Pharmacol. 2006 Jul;148(5):619-28. Epub 2006 May 15.

9.

The peptidic urotensin-II receptor ligand GSK248451 possesses less intrinsic activity than the low-efficacy partial agonists SB-710411 and urantide in native mammalian tissues and recombinant cell systems.

Behm DJ, Stankus G, Doe CP, Willette RN, Sarau HM, Foley JJ, Schmidt DB, Nuthulaganti P, Fornwald JA, Ames RS, Lambert DG, Calo' G, Camarda V, Aiyar NV, Douglas SA.

Br J Pharmacol. 2006 May;148(2):173-90.

10.

Heterologous expression of G protein-coupled receptors in U-2 OS osteosarcoma cells.

Ames R, Nuthulaganti P, Fornwald J, Shabon U, van-der-Keyl H, Elshourbagy N.

Receptors Channels. 2004;10(3-4):117-24.

PMID:
15512846
11.

BacMam recombinant baculoviruses in G protein-coupled receptor drug discovery.

Ames R, Fornwald J, Nuthulaganti P, Trill J, Foley J, Buckley P, Kost T, Wu Z, Romanos M.

Receptors Channels. 2004;10(3-4):99-107. Review.

PMID:
15512844
12.

A cell-based time-resolved fluorescence assay for selection of antibody reagents for G protein-coupled receptor immunohistochemistry.

Su JL, Fornwald J, Rivers P, Goldsworthy S, Looney NA, Hanvey J, Plumpton C, Parham J, Romanos M, Kost TA, Kull FC Jr.

J Immunol Methods. 2004 Aug;291(1-2):123-35.

PMID:
15345311
13.

A bicistronic expression system for bacterial production of authentic human interleukin-18.

Kirkpatrick RB, McDevitt PJ, Matico RE, Nwagwu S, Trulli SH, Mao J, Moore DD, Yorke AF, McLaughlin MM, Knecht KA, Elefante LC, Calamari AS, Fornwald JA, Trill JJ, Jonak ZL, Kane J, Patel PS, Sathe GM, Shatzman AR, Tapley PM, Johanson KO.

Protein Expr Purif. 2003 Feb;27(2):279-92.

PMID:
12597888
14.

Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542.

Laping NJ, Grygielko E, Mathur A, Butter S, Bomberger J, Tweed C, Martin W, Fornwald J, Lehr R, Harling J, Gaster L, Callahan JF, Olson BA.

Mol Pharmacol. 2002 Jul;62(1):58-64.

PMID:
12065755
15.

Identification of novel inhibitors of the transforming growth factor beta1 (TGF-beta1) type 1 receptor (ALK5).

Callahan JF, Burgess JL, Fornwald JA, Gaster LM, Harling JD, Harrington FP, Heer J, Kwon C, Lehr R, Mathur A, Olson BA, Weinstock J, Laping NJ.

J Med Chem. 2002 Feb 28;45(5):999-1001.

PMID:
11855979
16.

The human polo-like kinase, PLK, regulates cdc2/cyclin B through phosphorylation and activation of the cdc25C phosphatase.

Roshak AK, Capper EA, Imburgia C, Fornwald J, Scott G, Marshall LA.

Cell Signal. 2000 Jun;12(6):405-11.

PMID:
11202906
17.

Identification of potent, selective non-peptide CC chemokine receptor-3 antagonist that inhibits eotaxin-, eotaxin-2-, and monocyte chemotactic protein-4-induced eosinophil migration.

White JR, Lee JM, Dede K, Imburgia CS, Jurewicz AJ, Chan G, Fornwald JA, Dhanak D, Christmann LT, Darcy MG, Widdowson KL, Foley JJ, Schmidt DB, Sarau HM.

J Biol Chem. 2000 Nov 24;275(47):36626-31.

18.

Identification of a truncated form of the CC chemokine CK beta-8 demonstrating greatly enhanced biological activity.

Macphee CH, Appelbaum ER, Johanson K, Moores KE, Imburgia CS, Fornwald J, Berkhout T, Brawner M, Groot PH, O'Donnell K, O'Shannessy D, Scott G, White JR.

J Immunol. 1998 Dec 1;161(11):6273-9.

19.

Cloning and functional characterization of a novel human CC chemokine that binds to the CCR3 receptor and activates human eosinophils.

White JR, Imburgia C, Dul E, Appelbaum E, O'Donnell K, O'Shannessy DJ, Brawner M, Fornwald J, Adamou J, Elshourbagy NA, Kaiser K, Foley JJ, Schmidt DB, Johanson K, Macphee C, Moores K, McNulty D, Scott GF, Schleimer RP, Sarau HM.

J Leukoc Biol. 1997 Nov;62(5):667-75.

PMID:
9365122
20.

Native complex formation between apolipoprotein E isoforms and the Alzheimer's disease peptide A beta.

Chan W, Fornwald J, Brawner M, Wetzel R.

Biochemistry. 1996 Jun 4;35(22):7123-30.

PMID:
8679539
21.

Soluble forms of the human T cell receptor CD4 are efficiently expressed by Streptomyces lividans.

Fornwald JA, Donovan MJ, Gerber R, Keller J, Taylor DP, Arcuri EJ, Brawner ME.

Biotechnology (N Y). 1993 Sep;11(9):1031-6.

PMID:
7764928
22.

Two novel Streptomyces protein protease inhibitors. Purification, activity, cloning, and expression.

Strickler JE, Berka TR, Gorniak J, Fornwald J, Keys R, Rowland JJ, Rosenberg M, Taylor DP.

J Biol Chem. 1992 Feb 15;267(5):3236-41.

23.

Identification of the residues in human CD4 critical for the binding of HIV.

Arthos J, Deen KC, Chaikin MA, Fornwald JA, Sathe G, Sattentau QJ, Clapham PR, Weiss RA, McDougal JS, Pietropaolo C, et al.

Cell. 1989 May 5;57(3):469-81.

PMID:
2541915
24.

Gene organization and structure of the Streptomyces lividans gal operon.

Adams CW, Fornwald JA, Schmidt FJ, Rosenberg M, Brawner ME.

J Bacteriol. 1988 Jan;170(1):203-12.

25.

Two promoters, one inducible and one constitutive, control transcription of the Streptomyces lividans galactose operon.

Fornwald JA, Schmidt FJ, Adams CW, Rosenberg M, Brawner ME.

Proc Natl Acad Sci U S A. 1987 Apr;84(8):2130-4.

26.

Characterization of Streptomyces promoter sequences using the Escherichia coli galactokinase gene.

Brawner ME, Auerbach JI, Fornwald JA, Rosenberg M, Taylor DP.

Gene. 1985;40(2-3):191-201.

PMID:
3913624
27.

The complete nucleotide sequence of the chick a-actin gene and its evolutionary relationship to the actin gene family.

Fornwald JA, Kuncio G, Peng I, Ordahl CP.

Nucleic Acids Res. 1982 Jul 10;10(13):3861-76.

28.

Structure and developmental expression of the chick alpha-actin gene.

Ordahl CP, Tilghman SM, Ovitt C, Fornwald J, Largen MT.

Nucleic Acids Res. 1980 Nov 11;8(21):4989-5005.

29.

Molecular cloning of developmentally regulated, low-abundance mRNA sequences from embryonic muscle.

Ordahl CP, Kioussis D, Tilghman SM, Ovitt CE, Fornwald J.

Proc Natl Acad Sci U S A. 1980 Aug;77(8):4519-23.

30.

Nitrosation and mutagenicity of some amine drugs.

Andrews AW, Fornwald JA, Lijinsky W.

Toxicol Appl Pharmacol. 1980 Feb;52(2):237-44. No abstract available.

PMID:
6987779

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