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Use of Cell Cycle Arrest Biomarkers in Conjunction With Classical Markers of Acute Kidney Injury.

Joannidis M, Forni LG, Haase M, Koyner J, Shi J, Kashani K, Chawla LS, Kellum JA; Sapphire Investigators.

Crit Care Med. 2019 Jul 16. doi: 10.1097/CCM.0000000000003907. [Epub ahead of print]


Quality Improvement Goals for Acute Kidney Injury.

Kashani K, Rosner MH, Haase M, Lewington AJP, O'Donoghue DJ, Wilson FP, Nadim MK, Silver SA, Zarbock A, Ostermann M, Mehta RL, Kane-Gill SL, Ding X, Pickkers P, Bihorac A, Siew ED, Barreto EF, Macedo E, Kellum JA, Palevsky PM, Tolwani AJ, Ronco C, Juncos LA, Rewa OG, Bagshaw SM, Mottes TA, Koyner JL, Liu KD, Forni LG, Heung M, Wu VC.

Clin J Am Soc Nephrol. 2019 Jun 7;14(6):941-953. doi: 10.2215/CJN.01250119. Epub 2019 May 17.


Cytokine removal in human septic shock: Where are we and where are we going?

Honore PM, Hoste E, Molnár Z, Jacobs R, Joannes-Boyau O, Malbrain MLNG, Forni LG.

Ann Intensive Care. 2019 May 14;9(1):56. doi: 10.1186/s13613-019-0530-y. Review.


Understanding Lactatemia in Human Sepsis: Potential Impact for Early Management.

Gattinoni L, Vasques F, Camporota L, Meessen J, Romitti F, Pasticci I, Duscio E, Vassalli F, Forni LG, Payen D, Cressoni M, Zanella A, Latini R, Quintel M, Marini JJ.

Am J Respir Crit Care Med. 2019 Apr 15. doi: 10.1164/rccm.201812-2342OC. [Epub ahead of print]


Time to treat metabolic acidosis in the ICU with sodium bicarbonate?

Joannes-Boyau O, Forni LG.

Anaesth Crit Care Pain Med. 2018 Dec;37(6):493-494. doi: 10.1016/j.accpm.2018.11.004. No abstract available.


IDEAL timing of renal replacement therapy in critical care.

Forni LG, Joannidis M.

Nat Rev Nephrol. 2019 Jan;15(1):5-6. doi: 10.1038/s41581-018-0088-1. No abstract available.


Oliguria in critically ill patients: a narrative review.

Klein SJ, Lehner GF, Forni LG, Joannidis M.

J Nephrol. 2018 Dec;31(6):855-862. doi: 10.1007/s40620-018-0539-6. Epub 2018 Oct 8. Review.


NEWS 2 - too little evidence to implement?

Hodgson LE, Congleton J, Venn R, Forni LG, Roderick PJ.

Clin Med (Lond). 2018 Oct;18(5):371-373. doi: 10.7861/clinmedicine.18-5-371.


Correction: The ICE-AKI study: Impact analysis of a Clinical prediction rule and Electronic AKI alert in general medical patients.

Hodgson LE, Roderick PJ, Venn RM, Yao GL, Dimitrov BD, Forni LG.

PLoS One. 2018 Aug 23;13(8):e0203183. doi: 10.1371/journal.pone.0203183. eCollection 2018.


Manipulating the Microcirculation in Sepsis - the Impact of Vasoactive Medications on Microcirculatory Blood Flow: A Systematic Review.

Potter EK, Hodgson L, Creagh-Brown B, Forni LG.

Shock. 2019 Jul;52(1):5-12. doi: 10.1097/SHK.0000000000001239.


The ICE-AKI study: Impact analysis of a Clinical prediction rule and Electronic AKI alert in general medical patients.

Hodgson LE, Roderick PJ, Venn RM, Yao GL, Dimitrov BD, Forni LG.

PLoS One. 2018 Aug 8;13(8):e0200584. doi: 10.1371/journal.pone.0200584. eCollection 2018. Erratum in: PLoS One. 2018 Aug 23;13(8):e0203183.


Definitions and pathophysiology of vasoplegic shock.

Lambden S, Creagh-Brown BC, Hunt J, Summers C, Forni LG.

Crit Care. 2018 Jul 6;22(1):174. doi: 10.1186/s13054-018-2102-1. Review.


Improving clinical prediction rules in acute kidney injury with the use of biomarkers of cell cycle arrest: a pilot study.

Hodgson LE, Venn RM, Short S, Roderick PJ, Hargreaves D, Selby N, Forni LG.

Biomarkers. 2019 Feb;24(1):23-28. doi: 10.1080/1354750X.2018.1493617. Epub 2018 Dec 9.


Acute kidney injury and mild therapeutic hypothermia in patients after cardiopulmonary resuscitation - a post hoc analysis of a prospective observational trial.

Hasslacher J, Barbieri F, Harler U, Ulmer H, Forni LG, Bellmann R, Joannidis M.

Crit Care. 2018 Jun 8;22(1):154. doi: 10.1186/s13054-018-2061-6.


Cardiac and Vascular Surgery-Associated Acute Kidney Injury: The 20th International Consensus Conference of the ADQI (Acute Disease Quality Initiative) Group.

Nadim MK, Forni LG, Bihorac A, Hobson C, Koyner JL, Shaw A, Arnaoutakis GJ, Ding X, Engelman DT, Gasparovic H, Gasparovic V, Herzog CA, Kashani K, Katz N, Liu KD, Mehta RL, Ostermann M, Pannu N, Pickkers P, Price S, Ricci Z, Rich JB, Sajja LR, Weaver FA, Zarbock A, Ronco C, Kellum JA.

J Am Heart Assoc. 2018 Jun 1;7(11). pii: e008834. doi: 10.1161/JAHA.118.008834. No abstract available.


Outcomes in Patients with Vasodilatory Shock and Renal Replacement Therapy Treated with Intravenous Angiotensin II.

Tumlin JA, Murugan R, Deane AM, Ostermann M, Busse LW, Ham KR, Kashani K, Szerlip HM, Prowle JR, Bihorac A, Finkel KW, Zarbock A, Forni LG, Lynch SJ, Jensen J, Kroll S, Chawla LS, Tidmarsh GF, Bellomo R; Angiotensin II for the Treatment of High-Output Shock 3 (ATHOS-3) Investigators.

Crit Care Med. 2018 Jun;46(6):949-957. doi: 10.1097/CCM.0000000000003092.


Acute Kidney Injury Biomarkers: What Do They Tell Us?

Singh R, Dodkins J, Doyle JF, Forni LG.

Contrib Nephrol. 2018;193:21-34. doi: 10.1159/000484960. Epub 2018 Jan 23.


Renal complications of anaesthesia.

McKinlay J, Tyson E, Forni LG.

Anaesthesia. 2018 Jan;73 Suppl 1:85-94. doi: 10.1111/anae.14144. Review.


Pragmatic studies for acute kidney injury: Consensus report of the Acute Disease Quality Initiative (ADQI) 19 Workgroup.

Peng Z, Yu K, Ostermann M, Xi X, Hsu R, Vincent JL, Prowle JR, Du B, Gallagher M, Wang C, Murugan R, Qiu H, Rimmelé T, Li J, Forni LG, Kashani K, Ronco C, Kellum JA; Acute Disease Quality Initiative (ADQI) Workgroup 19.

J Crit Care. 2018 Apr;44:337-344. doi: 10.1016/j.jcrc.2017.12.006. Epub 2017 Dec 12.


Acute kidney injury associated with endurance events-is it a cause for concern? A systematic review.

Hodgson LE, Walter E, Venn RM, Galloway R, Pitsiladis Y, Sardat F, Forni LG.

BMJ Open Sport Exerc Med. 2017 Jun 14;3(1):e000093. doi: 10.1136/bmjsem-2015-000093. eCollection 2017.


Kinetics of Urinary Cell Cycle Arrest Markers for Acute Kidney Injury Following Exposure to Potential Renal Insults.

Ostermann M, McCullough PA, Forni LG, Bagshaw SM, Joannidis M, Shi J, Kashani K, Honore PM, Chawla LS, Kellum JA; all SAPPHIRE Investigators.

Crit Care Med. 2018 Mar;46(3):375-383. doi: 10.1097/CCM.0000000000002847.


Can this patient be safely weaned from RRT?

Klouche K, Gibney RTN, Forni LG.

Intensive Care Med. 2018 May;44(5):639-642. doi: 10.1007/s00134-017-4948-0. Epub 2017 Oct 20. No abstract available.


Drug management in acute kidney disease - Report of the Acute Disease Quality Initiative XVI meeting.

Ostermann M, Chawla LS, Forni LG, Kane-Gill SL, Kellum JA, Koyner J, Murray PT, Ronco C, Goldstein SL; ADQI 16 workgroup.

Br J Clin Pharmacol. 2018 Feb;84(2):396-403. doi: 10.1111/bcp.13449. Epub 2017 Dec 1.


Systematic review of prognostic prediction models for acute kidney injury (AKI) in general hospital populations.

Hodgson LE, Sarnowski A, Roderick PJ, Dimitrov BD, Venn RM, Forni LG.

BMJ Open. 2017 Sep 27;7(9):e016591. doi: 10.1136/bmjopen-2017-016591. Review.


Vitamin D levels in critically ill patients with acute kidney injury: a protocol for a prospective cohort study (VID-AKI).

Cameron LK, Lei K, Smith S, Doyle NL, Doyle JF, Flynn K, Purchase N, Smith J, Chan K, Kamara F, Kidane NG, Forni LG, Harrington D, Hampson G, Ostermann M.

BMJ Open. 2017 Jul 12;7(7):e016486. doi: 10.1136/bmjopen-2017-016486.


Prevention of acute kidney injury and protection of renal function in the intensive care unit: update 2017 : Expert opinion of the Working Group on Prevention, AKI section, European Society of Intensive Care Medicine.

Joannidis M, Druml W, Forni LG, Groeneveld ABJ, Honore PM, Hoste E, Ostermann M, Oudemans-van Straaten HM, Schetz M.

Intensive Care Med. 2017 Jun;43(6):730-749. doi: 10.1007/s00134-017-4832-y. Epub 2017 Jun 2. Review.


Blood pressure deficits in acute kidney injury: not all about the mean arterial pressure?

Forni LG, Joannidis M.

Crit Care. 2017 May 4;21(1):102. doi: 10.1186/s13054-017-1683-4.


Renal recovery after acute kidney injury.

Forni LG, Darmon M, Ostermann M, Oudemans-van Straaten HM, Pettilä V, Prowle JR, Schetz M, Joannidis M.

Intensive Care Med. 2017 Jun;43(6):855-866. doi: 10.1007/s00134-017-4809-x. Epub 2017 May 2. Review.


Myocardial stunning occurs during intermittent haemodialysis for acute kidney injury.

Mahmoud H, Forni LG, McIntyre CW, Selby NM.

Intensive Care Med. 2017 Jun;43(6):942-944. doi: 10.1007/s00134-017-4768-2. Epub 2017 Mar 28. No abstract available.


Predicting AKI in emergency admissions: an external validation study of the acute kidney injury prediction score (APS).

Hodgson LE, Dimitrov BD, Roderick PJ, Venn R, Forni LG.

BMJ Open. 2017 Mar 8;7(3):e013511. doi: 10.1136/bmjopen-2016-013511.


Renal replacement in 2050: from renal support to renal replacement?

Forni LG, Darmon M, Schetz M.

Intensive Care Med. 2017 Jul;43(7):1044-1047. doi: 10.1007/s00134-016-4664-1. Epub 2017 Feb 4. No abstract available.


Update on sepsis-associated acute kidney injury: emerging targeted therapies.

Doyle JF, Forni LG.

Biologics. 2016 Nov 7;10:149-156. eCollection 2016. Review.


Oliguria and Biomarkers of Acute Kidney Injury: Star Struck Lovers or Strangers in the Night?

Lehner GF, Forni LG, Joannidis M.

Nephron. 2016;134(3):183-190. Epub 2016 Aug 10.


Precision and improving outcomes in acute kidney injury: Personalizing the approach.

Forni LG, Chawla L, Ronco C.

J Crit Care. 2017 Feb;37:244-245. doi: 10.1016/j.jcrc.2016.08.027. Epub 2016 Sep 13.


A validation of the National Early Warning Score to predict outcome in patients with COPD exacerbation.

Hodgson LE, Dimitrov BD, Congleton J, Venn R, Forni LG, Roderick PJ.

Thorax. 2017 Jan;72(1):23-30. doi: 10.1136/thoraxjnl-2016-208436. Epub 2016 Aug 23.


The two sides of creatinine: both as bad as each other?

Ostermann M, Kashani K, Forni LG.

J Thorac Dis. 2016 Jul;8(7):E628-30. doi: 10.21037/jtd.2016.05.36. No abstract available.


Acute kidney injury: short-term and long-term effects.

Doyle JF, Forni LG.

Crit Care. 2016 Jul 4;20(1):188. doi: 10.1186/s13054-016-1353-y. Review.


Goal-directed therapy and acute kidney injury: as good as it gets?

Doyle JF, Ostermann M, Forni LG.

Crit Care. 2016 Jun 25;20(1):174. doi: 10.1186/s13054-016-1346-x.


Measuring the cardiac output in acute emergency admissions: use of the non-invasive ultrasonic cardiac output monitor (USCOM) with determination of the learning curve and inter-rater reliability.

Hodgson LE, Venn R, Forni LG, Samuels TL, Wakeling HG.

J Intensive Care Soc. 2016 May;17(2):122-128. doi: 10.1177/1751143715619186. Epub 2015 Dec 10.


A comparison of the non-invasive ultrasonic cardiac output monitor (USCOM) with the oesophageal Doppler monitor during major abdominal surgery.

Hodgson LE, Forni LG, Venn R, Samuels TL, Wakeling HG.

J Intensive Care Soc. 2016 May;17(2):103-110. doi: 10.1177/1751143715610785. Epub 2015 Oct 14.


Treating Acute Kidney Injury. One Less Weapon in the Armamentarium?

Hoste EA, De Loor J, Forni LG.

Am J Respir Crit Care Med. 2016 Feb 1;193(3):232-3. doi: 10.1164/rccm.201509-1900ED. No abstract available.


Fluid overload and acute kidney injury: cause or consequence?

Ostermann M, Straaten HM, Forni LG.

Crit Care. 2015 Dec 27;19:443. doi: 10.1186/s13054-015-1163-7.


Does this patient with AKI need RRT?

Schetz M, Forni LG, Joannidis M.

Intensive Care Med. 2016 Jul;42(7):1155-8. doi: 10.1007/s00134-015-4186-2. Epub 2015 Dec 21. No abstract available.


Peri-operative renal dysfunction: prevention and management.

Golden D, Corbett J, Forni LG.

Anaesthesia. 2016 Jan;71 Suppl 1:51-7. doi: 10.1111/anae.13313. Review.


Acute kidney injury: Buffered crystalloids or saline in the ICU--a SPLIT decision.

Joannidis M, Forni LG.

Nat Rev Nephrol. 2016 Jan;12(1):6-8. doi: 10.1038/nrneph.2015.190. Epub 2015 Nov 23. No abstract available.


Bioelectrical impedance vector analysis in the critically ill: cool tool or just another 'toy'?

Forni LG, Hasslacher J, Joannidis M.

Crit Care. 2015 Nov 11;19:387. doi: 10.1186/s13054-015-1110-7.


Long-Term Follow-up of Acute Kidney Injury.

Doyle JF, Forni LG.

Crit Care Clin. 2015 Oct;31(4):763-72. doi: 10.1016/j.ccc.2015.06.017. Review.


An external validation study of a clinical prediction rule for medical patients with suspected bacteraemia.

Hodgson LE, Dragolea N, Venn R, Dimitrov BD, Forni LG.

Emerg Med J. 2016 Feb;33(2):124-9. doi: 10.1136/emermed-2015-204926. Epub 2015 Aug 5.


Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study.

Hoste EA, Bagshaw SM, Bellomo R, Cely CM, Colman R, Cruz DN, Edipidis K, Forni LG, Gomersall CD, Govil D, Honoré PM, Joannes-Boyau O, Joannidis M, Korhonen AM, Lavrentieva A, Mehta RL, Palevsky P, Roessler E, Ronco C, Uchino S, Vazquez JA, Vidal Andrade E, Webb S, Kellum JA.

Intensive Care Med. 2015 Aug;41(8):1411-23. doi: 10.1007/s00134-015-3934-7. Epub 2015 Jul 11.


Balancing the "humors" in severe sepsis: still a role for extracorporeal therapies?

Darmon M, Bagshaw SM, Forni LG.

Intensive Care Med. 2015 Jun;41(6):1132-4. doi: 10.1007/s00134-015-3801-6. Epub 2015 May 14. No abstract available.


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