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Items: 1 to 50 of 245


Keap1 controls protein S-nitrosation and apoptosis-senescence switch in endothelial cells.

Kopacz A, Klóska D, Proniewski B, Cysewski D, Personnic N, Piechota-Polańczyk A, Kaczara P, Zakrzewska A, Forman HJ, Dulak J, Józkowicz A, Grochot-Przęczek A.

Redox Biol. 2019 Aug 22;28:101304. doi: 10.1016/j.redox.2019.101304. [Epub ahead of print]


Silencing Bach1 alters aging-related changes in the expression of Nrf2-regulated genes in primary human bronchial epithelial cells.

Zhang H, Zhou L, Davies KJA, Forman HJ.

Arch Biochem Biophys. 2019 Sep 15;672:108074. doi: 10.1016/ Epub 2019 Aug 15. Review.


Erythrocyte and plasma oxidative stress appears to be compensated in patients with sickle cell disease during a period of relative health, despite the presence of known oxidative agents.

Detterich JA, Liu H, Suriany S, Kato RM, Chalacheva P, Tedla B, Shah PM, Khoo MC, Wood JC, Coates TD, Milne GL, Oh JY, Patel RP, Forman HJ.

Free Radic Biol Med. 2019 Sep;141:408-415. doi: 10.1016/j.freeradbiomed.2019.07.004. Epub 2019 Jul 3.


Limitations to adaptive homeostasis in an hyperoxia-induced model of accelerated ageing.

Pomatto LCD, Sun PY, Yu K, Gullapalli S, Bwiza CP, Sisliyan C, Wong S, Zhang H, Forman HJ, Oliver PL, Davies KE, Davies KJA.

Redox Biol. 2019 Jun;24:101194. doi: 10.1016/j.redox.2019.101194. Epub 2019 Apr 14.


Surface characterization and chemical speciation of adsorbed iron(iii) on oxidized carbon nanoparticles.

Pattammattel A, Leppert VJ, Forman HJ, O'Day PA.

Environ Sci Process Impacts. 2019 Mar 20;21(3):548-563. doi: 10.1039/c8em00545a.


Does Bach1 & c-Myc dependent redox dysregulation of Nrf2 & adaptive homeostasis decrease cancer risk in ageing?

Davies KJA, Forman HJ.

Free Radic Biol Med. 2019 Apr;134:708-714. doi: 10.1016/j.freeradbiomed.2019.01.028. Epub 2019 Jan 26. Review.


Oxidation of Peroxiredoxin 6 in the Presence of GSH Increases its Phospholipase A₂ Activity at Cytoplasmic pH.

Zhou S, Dodia C, Feinstein SI, Harper S, Forman HJ, Speicher DW, Fisher AB.

Antioxidants (Basel). 2018 Dec 24;8(1). pii: E4. doi: 10.3390/antiox8010004.


Nrf2-related gene expression is impaired during a glucose challenge in type II diabetic rat hearts.

Thorwald MA, Godoy-Lugo JA, Rodriguez GJ, Rodriguez MA, Jamal M, Kinoshita H, Nakano D, Nishiyama A, Forman HJ, Ortiz RM.

Free Radic Biol Med. 2019 Jan;130:306-317. doi: 10.1016/j.freeradbiomed.2018.10.405. Epub 2018 Oct 11.


Rust never sleeps: The continuing story of the Iron Bolt.

van der Vliet A, Dick TP, Aust SD, Koppenol WH, Ursini F, Kettle AJ, Beckman JS, O'Donnell V, Darley-Usmar V, Lancaster J Jr, Hogg N, Davies KJA, Forman HJ, Janssen-Heininger YMW.

Free Radic Biol Med. 2018 Aug 20;124:353-357. doi: 10.1016/j.freeradbiomed.2018.06.017. Epub 2018 Jun 18. Review.


Aging attenuates redox adaptive homeostasis and proteostasis in female mice exposed to traffic-derived nanoparticles ('vehicular smog').

Pomatto LCD, Cline M, Woodward N, Pakbin P, Sioutas C, Morgan TE, Finch CE, Forman HJ, Davies KJA.

Free Radic Biol Med. 2018 Jun;121:86-97. doi: 10.1016/j.freeradbiomed.2018.04.574. Epub 2018 Apr 27.


Redox control of cancer cell destruction.

Hegedűs C, Kovács K, Polgár Z, Regdon Z, Szabó É, Robaszkiewicz A, Forman HJ, Martner A, Virág L.

Redox Biol. 2018 Jun;16:59-74. doi: 10.1016/j.redox.2018.01.015. Epub 2018 Feb 3. Review.


A critical review of assays for hazardous components of air pollution.

Forman HJ, Finch CE.

Free Radic Biol Med. 2018 Mar;117:202-217. doi: 10.1016/j.freeradbiomed.2018.01.030. Epub 2018 Jan 31. Review.


The Oxygen Paradox, the French Paradox, and age-related diseases.

Davies JMS, Cillard J, Friguet B, Cadenas E, Cadet J, Cayce R, Fishmann A, Liao D, Bulteau AL, Derbré F, Rébillard A, Burstein S, Hirsch E, Kloner RA, Jakowec M, Petzinger G, Sauce D, Sennlaub F, Limon I, Ursini F, Maiorino M, Economides C, Pike CJ, Cohen P, Salvayre AN, Halliday MR, Lundquist AJ, Jakowec NA, Mechta-Grigoriou F, Mericskay M, Mariani J, Li Z, Huang D, Grant E, Forman HJ, Finch CE, Sun PY, Pomatto LCD, Agbulut O, Warburton D, Neri C, Rouis M, Cillard P, Capeau J, Rosenbaum J, Davies KJA.

Geroscience. 2017 Dec;39(5-6):499-550. doi: 10.1007/s11357-017-0002-y. Epub 2017 Dec 21. Review.


Temporal changes in glutathione biosynthesis during the lipopolysaccharide-induced inflammatory response of THP-1 macrophages.

Zhang H, Liu H, Zhou L, Yuen J, Forman HJ.

Free Radic Biol Med. 2017 Dec;113:304-310. doi: 10.1016/j.freeradbiomed.2017.10.010. Epub 2017 Oct 7.


Aging-related decline in the induction of Nrf2-regulated antioxidant genes in human bronchial epithelial cells.

Zhou L, Zhang H, Davies KJA, Forman HJ.

Redox Biol. 2018 Apr;14:35-40. doi: 10.1016/j.redox.2017.08.014. Epub 2017 Aug 24.


Association of GCLM -588C/T and GCLC -129T/C Promoter Polymorphisms of Genes Coding the Subunits of Glutamate Cysteine Ligase with Ischemic Heart Disease Development in Kazakhstan Population.

Skvortsova L, Perfelyeva A, Khussainova E, Mansharipova A, Forman HJ, Djansugurova L.

Dis Markers. 2017;2017:4209257. doi: 10.1155/2017/4209257. Epub 2017 Jul 5.


Low dose inflammatory potential of silica particles in human-derived THP-1 macrophage cell culture studies - Mechanism and effects of particle size and iron.

Premshekharan G, Nguyen K, Zhang H, Forman HJ, Leppert VJ.

Chem Biol Interact. 2017 Jun 25;272:160-171. doi: 10.1016/j.cbi.2017.05.004. Epub 2017 May 13.


Multi-walled carbon nanotubes: A cytotoxicity study in relation to functionalization, dose and dispersion.

Zhou L, Forman HJ, Ge Y, Lunec J.

Toxicol In Vitro. 2017 Aug;42:292-298. doi: 10.1016/j.tiv.2017.04.027. Epub 2017 May 5.


Delayed Nrf2-regulated antioxidant gene induction in response to silica nanoparticles.

Zhang H, Zhou L, Yuen J, Birkner N, Leppert V, O'Day PA, Forman HJ.

Free Radic Biol Med. 2017 Jul;108:311-319. doi: 10.1016/j.freeradbiomed.2017.04.002. Epub 2017 Apr 4.


Introduction for the special issue on the chemistry of redox signaling.

Forman HJ, Koppenol WH.

Arch Biochem Biophys. 2017 Mar 1;617:1-2. doi: 10.1016/ Epub 2017 Jan 11. No abstract available.


4-hydroxynonenal-mediated signaling and aging.

Zhang H, Forman HJ.

Free Radic Biol Med. 2017 Oct;111:219-225. doi: 10.1016/j.freeradbiomed.2016.11.032. Epub 2016 Nov 20. Review.


Signaling by 4-hydroxy-2-nonenal: Exposure protocols, target selectivity and degradation.

Zhang H, Forman HJ.

Arch Biochem Biophys. 2017 Mar 1;617:145-154. doi: 10.1016/ Epub 2016 Nov 10. Review.


Protein cysteine oxidation in redox signaling: Caveats on sulfenic acid detection and quantification.

Forman HJ, Davies MJ, Krämer AC, Miotto G, Zaccarin M, Zhang H, Ursini F.

Arch Biochem Biophys. 2017 Mar 1;617:26-37. doi: 10.1016/ Epub 2016 Sep 28. Review.


Corrigendum to "What is the concentration of hydrogen peroxide in blood and plasma?" [Arch. Biochem. Biophys. 603 (2016) 48-53].

Forman HJ, Bernardo A, Davies KJ.

Arch Biochem Biophys. 2016 Oct 1;607:7. doi: 10.1016/ Epub 2016 Aug 20. No abstract available.


Redox signaling: An evolution from free radicals to aging.

Forman HJ.

Free Radic Biol Med. 2016 Aug;97:398-407. doi: 10.1016/j.freeradbiomed.2016.07.003. Epub 2016 Jul 5. Review.


Nanoscale Particulate Matter from Urban Traffic Rapidly Induces Oxidative Stress and Inflammation in Olfactory Epithelium with Concomitant Effects on Brain.

Cheng H, Saffari A, Sioutas C, Forman HJ, Morgan TE, Finch CE.

Environ Health Perspect. 2016 Oct;124(10):1537-1546. Epub 2016 May 17.


What is the concentration of hydrogen peroxide in blood and plasma?

Forman HJ, Bernardo A, Davies KJ.

Arch Biochem Biophys. 2016 Aug 1;603:48-53. doi: 10.1016/ Epub 2016 May 9. Review.


Glutathione - From antioxidant to post-translational modifier.

Forman HJ.

Arch Biochem Biophys. 2016 Apr 1;595:64-7. doi: 10.1016/


Tribute issue: Helmut Sies and oxidative stress: Venit, vidit, vicit.

Forman HJ, Toyokuni S.

Arch Biochem Biophys. 2016 Apr 1;595:2. doi: 10.1016/ No abstract available.


Transit of H2O2 across the endoplasmic reticulum membrane is not sluggish.

Appenzeller-Herzog C, Bánhegyi G, Bogeski I, Davies KJ, Delaunay-Moisan A, Forman HJ, Görlach A, Kietzmann T, Laurindo F, Margittai E, Meyer AJ, Riemer J, Rützler M, Simmen T, Sitia R, Toledano MB, Touw IP.

Free Radic Biol Med. 2016 May;94:157-60. doi: 10.1016/j.freeradbiomed.2016.02.030. Epub 2016 Feb 27.


Redox homeostasis: The Golden Mean of healthy living.

Ursini F, Maiorino M, Forman HJ.

Redox Biol. 2016 Aug;8:205-15. doi: 10.1016/j.redox.2016.01.010. Epub 2016 Jan 19.


Commentary on "Bach1 differentially regulates distinct Nrf2-dependent genes in human venous and coronary artery endothelial cells adapted to physiological oxygen levels" by Chapple et al.

Forman HJ, Davies KJA.

Free Radic Biol Med. 2016 Mar;92:163-164. doi: 10.1016/j.freeradbiomed.2016.01.013. Epub 2016 Jan 21. No abstract available.


TGFβ1 rapidly activates Src through a non-canonical redox mechanism.

Zhang H, Forman HJ.

Free Radic Biol Med. 2014 Oct;75 Suppl 1:S4. doi: 10.1016/j.freeradbiomed.2014.10.831. Epub 2014 Dec 10.


4-Hydroxynonenal activates Src through a non-canonical pathway that involves EGFR/PTP1B.

Zhang H, Forman HJ.

Free Radic Biol Med. 2015 Dec;89:701-7. doi: 10.1016/j.freeradbiomed.2015.08.025. Epub 2015 Oct 8.


Introduction to Special Issue on 'Nrf2 Regulated Redox Signaling and Metabolism in Physiology and Medicine.

Mann GE, Forman HJ.

Free Radic Biol Med. 2015 Nov;88(Pt B):91-92. doi: 10.1016/j.freeradbiomed.2015.08.002. Epub 2015 Aug 21. No abstract available.


Impaired enzymatic defensive activity, mitochondrial dysfunction and proteasome activation are involved in RTT cell oxidative damage.

Cervellati C, Sticozzi C, Romani A, Belmonte G, De Rasmo D, Signorile A, Cervellati F, Milanese C, Mastroberardino PG, Pecorelli A, Savelli V, Forman HJ, Hayek J, Valacchi G.

Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2066-74. doi: 10.1016/j.bbadis.2015.07.014. Epub 2015 Jul 17.


Oxidative stress response and Nrf2 signaling in aging.

Zhang H, Davies KJA, Forman HJ.

Free Radic Biol Med. 2015 Nov;88(Pt B):314-336. doi: 10.1016/j.freeradbiomed.2015.05.036. Epub 2015 Jun 9. Review.


TGFβ1 rapidly activates Src through a non-canonical redox signaling mechanism.

Zhang H, Davies KJ, Forman HJ.

Arch Biochem Biophys. 2015 Feb 15;568:1-7. doi: 10.1016/ Epub 2015 Jan 10.


Glutathione peroxidase 8 is transcriptionally regulated by HIFα and modulates growth factor signaling in HeLa cells.

Bosello-Travain V, Forman HJ, Roveri A, Toppo S, Ursini F, Venerando R, Warnecke C, Zaccarin M, Maiorino M.

Free Radic Biol Med. 2015 Apr;81:58-68. doi: 10.1016/j.freeradbiomed.2014.12.020. Epub 2015 Jan 1.


Even free radicals should follow some rules: a guide to free radical research terminology and methodology.

Forman HJ, Augusto O, Brigelius-Flohe R, Dennery PA, Kalyanaraman B, Ischiropoulos H, Mann GE, Radi R, Roberts LJ 2nd, Vina J, Davies KJ.

Free Radic Biol Med. 2015 Jan;78:233-5. doi: 10.1016/j.freeradbiomed.2014.10.504. Epub 2014 Oct 23.


NADPH oxidase activation and 4-hydroxy-2-nonenal/aquaporin-4 adducts as possible new players in oxidative neuronal damage presents in drug-resistant epilepsy.

Pecorelli A, Natrella F, Belmonte G, Miracco C, Cervellati F, Ciccoli L, Mariottini A, Rocchi R, Vatti G, Bua A, Canitano R, Hayek J, Forman HJ, Valacchi G.

Biochim Biophys Acta. 2015 Mar;1852(3):507-19. doi: 10.1016/j.bbadis.2014.11.016. Epub 2014 Nov 22.


The 'mitoflash' probe cpYFP does not respond to superoxide.

Schwarzländer M, Wagner S, Ermakova YG, Belousov VV, Radi R, Beckman JS, Buettner GR, Demaurex N, Duchen MR, Forman HJ, Fricker MD, Gems D, Halestrap AP, Halliwell B, Jakob U, Johnston IG, Jones NS, Logan DC, Morgan B, Müller FL, Nicholls DG, Remington SJ, Schumacker PT, Winterbourn CC, Sweetlove LJ, Meyer AJ, Dick TP, Murphy MP.

Nature. 2014 Oct 23;514(7523):E12-4. doi: 10.1038/nature13858. No abstract available.


Comparative effects between electronic and cigarette smoke in human keratinocytes and epithelial lung cells.

Cervellati F, Muresan XM, Sticozzi C, Gambari R, Montagner G, Forman HJ, Torricelli C, Maioli E, Valacchi G.

Toxicol In Vitro. 2014 Aug;28(5):999-1005. doi: 10.1016/j.tiv.2014.04.012. Epub 2014 May 5.


Antioxidants in the intensive care unit.

Fisher AB, Forman HJ.

Am J Respir Crit Care Med. 2014 Apr 15;189(8):1007-8. doi: 10.1164/rccm.201401-0156LE. No abstract available.


Arginine starvation impairs mitochondrial respiratory function in ASS1-deficient breast cancer cells.

Qiu F, Chen YR, Liu X, Chu CY, Shen LJ, Xu J, Gaur S, Forman HJ, Zhang H, Zheng S, Yen Y, Huang J, Kung HJ, Ann DK.

Sci Signal. 2014 Apr 1;7(319):ra31. doi: 10.1126/scisignal.2004761.


An overview of mechanisms of redox signaling.

Forman HJ, Ursini F, Maiorino M.

J Mol Cell Cardiol. 2014 Aug;73:2-9. doi: 10.1016/j.yjmcc.2014.01.018. Epub 2014 Feb 8. Review.


Resveratrol protects SR-B1 levels in keratinocytes exposed to cigarette smoke.

Sticozzi C, Belmonte G, Cervellati F, Muresan XM, Pessina F, Lim Y, Forman HJ, Valacchi G.

Free Radic Biol Med. 2014 Apr;69:50-7. doi: 10.1016/j.freeradbiomed.2014.01.007. Epub 2014 Jan 12.


Antioxidants: GRABbing new headlines.

Forman HJ, Traber M, Ursini F.

Free Radic Biol Med. 2014 Jan;66:1-2. doi: 10.1016/j.freeradbiomed.2013.10.808. Epub 2013 Oct 17. No abstract available.


Competition of nuclear factor-erythroid 2 factors related transcription factor isoforms, Nrf1 and Nrf2, in antioxidant enzyme induction.

Chepelev NL, Zhang H, Liu H, McBride S, Seal AJ, Morgan TE, Finch CE, Willmore WG, Davies KJ, Forman HJ.

Redox Biol. 2013 Jan 19;1:183-9. doi: 10.1016/j.redox.2013.01.005. eCollection 2013.


Reactive oxygen and nitrogen species in neurodegeneration.

Andersen JK, Davies KJA, Forman HJ.

Free Radic Biol Med. 2013 Sep;62:1-3. doi: 10.1016/j.freeradbiomed.2013.06.001. No abstract available.


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