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Aurora A selective inhibitor LY3295668 leads to dominant mitotic arrest, apoptosis in cancer cells and shows potent preclinical antitumor efficacy.

Du J, Yan L, Torres R, Gong X, Bian H, Marugán C, Boehnke K, Baquero C, Hui YH, Chapman SC, Yang Y, Zeng Y, Bogner SM, Foreman RT, Capen A, Donoho GP, Van Horn RD, Barnard DS, Dempsey JA, Beckmann RP, Marshall MS, Chio LC, Qian Y, Webster YW, Aggarwal A, Chu S, Bhattachar S, Stancato LF, Dowless MS, Iversen PW, Manro JR, Walgren JL, Halstead BW, Dieter MZ, Martinez R, Bhagwat SV, Kreklau EL, Lallena MJ, Ye XS, Patel BKR, Reinhard C, Plowman GD, Barda DA, Henry JR, Buchanan SG, Campbell RM.

Mol Cancer Ther. 2019 Sep 17. pii: molcanther.0529.2018. doi: 10.1158/1535-7163.MCT-18-0529. [Epub ahead of print]


Kīlauea lava fuels phytoplankton bloom in the North Pacific Ocean.

Wilson ST, Hawco NJ, Armbrust EV, Barone B, Björkman KM, Boysen AK, Burgos M, Burrell TJ, Casey JR, DeLong EF, Dugenne M, Dutkiewicz S, Dyhrman ST, Ferrón S, Follows MJ, Foreman RK, Funkey CP, Harke MJ, Henke BA, Hill CN, Hynes AM, Ingalls AE, Jahn O, Kelly RL, Knapp AN, Letelier RM, Ribalet F, Shimabukuro EM, Tabata RKS, Turk-Kubo KA, White AE, Zehr JP, John S, Karl DM.

Science. 2019 Sep 6;365(6457):1040-1044. doi: 10.1126/science.aax4767.


Improving the Monitoring of Cardiac Rehabilitation Delivery and Quality: A Call to Action for Australia.

Thomas E, Astley C, Gallagher R, Foreman R, Mitchell JA, Grace SL, Cadilhac DA, Bunker S, Clark A, O'Neil A.

Heart Lung Circ. 2019 Aug 16. pii: S1443-9506(19)31400-3. doi: 10.1016/j.hlc.2019.07.013. [Epub ahead of print] No abstract available.


Sacral nerve stimulation with appropriate parameters improves constipation in rats by enhancing colon motility mediated via the autonomic-cholinergic mechanisms.

Huang Z, Li S, Foreman RD, Yin J, Dai N, Chen JD.

Am J Physiol Gastrointest Liver Physiol. 2019 Aug 14. doi: 10.1152/ajpgi.00150.2018. [Epub ahead of print]


Variable loss of CD30 expression by immunohistochemistry in recurrent cutaneous CD30+ lymphoid neoplasms treated with brentuximab vedotin.

Goyal A, Patel S, Goyal K, Morgan EA, Foreman RK.

J Cutan Pathol. 2019 Jul 9. doi: 10.1111/cup.13545. [Epub ahead of print]


Autonomically mediated anti-inflammatory effects of electrical stimulation at acupoints in a rodent model of colonic inflammation.

Jin H, Guo J, Liu J, Lyu B, Foreman RD, Shi Z, Yin J, Chen JDZ.

Neurogastroenterol Motil. 2019 Aug;31(8):1-12. doi: 10.1111/nmo.13615. Epub 2019 May 22.


Ameliorating Effects of Electroacupuncture on Dysmotility, Inflammation, and Pain Mediated via the Autonomic Mechanism in a Rat Model of Postoperative Ileus.

Murakami H, Li S, Foreman R, Yin J, Hirai T, Chen JDZ.

J Neurogastroenterol Motil. 2019 Apr 30;25(2):286-299. doi: 10.5056/jnm18094.


Case 2-2019: A 36-Year-Old Man with Rash, Abdominal Pain, and Lymphadenopathy.

Chen ST, Cahalane AM, Ryan ET, Foreman RK.

N Engl J Med. 2019 Jan 17;380(3):275-283. doi: 10.1056/NEJMcpc1810390. No abstract available.


Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models.

Brooks HB, Meier TI, Geeganage S, Fales KR, Thrasher KJ, Konicek SA, Spencer CD, Thibodeaux S, Foreman RT, Hui YH, Roth KD, Qian YW, Wang T, Luo S, Torrado A, Si C, Toth JL, Mc Cowan JR, Frimpong K, Lee MR, Dally RD, Shepherd TA, Durham TB, Wang Y, Wu Z, Iversen PW, Njoroge FG.

Sci Rep. 2018 Oct 18;8(1):15458. doi: 10.1038/s41598-018-33453-4.


Intraoperative Vagus Nerve Stimulation Accelerates Postoperative Recovery in Rats.

Murakami H, Li S, Foreman R, Yin J, Hirai T, Chen JDZ.

J Gastrointest Surg. 2019 Feb;23(2):320-330. doi: 10.1007/s11605-018-3969-5. Epub 2018 Sep 27.


Dependence of c-fos Expression on Amplitude of High-Frequency Spinal Cord Stimulation in a Rodent Model.

Li S, Ye F, Farber JP, Linderoth B, Zhang T, Gu JW, Moffitt M, Garrett K, Chen J, Foreman RD.

Neuromodulation. 2019 Feb;22(2):172-178. doi: 10.1111/ner.12852. Epub 2018 Sep 17.


Template-assisted synthesis of adenine-mutagenized cDNA by a retroelement protein complex.

Handa S, Jiang Y, Tao S, Foreman R, Schinazi RF, Miller JF, Ghosh P.

Nucleic Acids Res. 2018 Oct 12;46(18):9711-9725. doi: 10.1093/nar/gky620.


Electroacupuncture via chronically implanted electrodes improves gastric dysmotility mediated by autonomic-cholinergic mechanisms in a rodent model of functional dyspepsia.

Zhang S, Li S, Liu Y, Ye F, Yin J, Foreman RD, Wang D, Chen JDZ.

Neurogastroenterol Motil. 2018 Oct;30(10):e13381. doi: 10.1111/nmo.13381. Epub 2018 Jun 1.


Case 14-2018: A 68-Year-Old Woman with a Rash, Hyponatremia, and Uveitis.

Paras ML, Hyle EP, Foreman RK, Coffey KC.

N Engl J Med. 2018 May 10;378(19):1825-1833. doi: 10.1056/NEJMcpc1800337. No abstract available.


A 92-Year-Old Male with Eosinophilic Asthma Presenting with Recurrent Palpable Purpuric Plaques.

Negbenebor NA, Khalifian S, Foreman RK, Kroshinsky D.

Dermatopathology (Basel). 2018 Mar 16;5(1):44-48. doi: 10.1159/000485969. eCollection 2018 Jan-Mar.


First in situ evidence of wakes in the far field behind offshore wind farms.

Platis A, Siedersleben SK, Bange J, Lampert A, Bärfuss K, Hankers R, Cañadillas B, Foreman R, Schulz-Stellenfleth J, Djath B, Neumann T, Emeis S.

Sci Rep. 2018 Feb 1;8(1):2163. doi: 10.1038/s41598-018-20389-y.


Obituary Prof. Dr. med. D. Sc. h.c. Robert F. Schmidt, Ph.D.

Flor H, Foreman RD, Gebhart GF, Jänig W, Schaible HG.

Pain. 2018 Jan 29. doi: 10.1097/j.pain.0000000000001159. [Epub ahead of print] No abstract available.


An Autologous Anti-Inflammatory Protein Solution Yielded a Favorable Safety Profile and Significant Pain Relief in an Open-Label Pilot Study of Patients with Osteoarthritis.

Hix J, Klaassen M, Foreman R, Cullen E, Toler K, King W, Woodell-May J.

Biores Open Access. 2017 Dec 1;6(1):151-158. doi: 10.1089/biores.2017.0027. eCollection 2017.


Spinal Cord Stimulation With "Conventional Clinical" and Higher Frequencies on Activity and Responses of Spinal Neurons to Noxious Stimuli: An Animal Study.

Li S, Farber JP, Linderoth B, Chen J, Foreman RD.

Neuromodulation. 2018 Jul;21(5):440-447. doi: 10.1111/ner.12725. Epub 2017 Nov 22.


Conventional and Novel Spinal Stimulation Algorithms: Hypothetical Mechanisms of Action and Comments on Outcomes.

Linderoth B, Foreman RD.

Neuromodulation. 2017 Aug;20(6):525-533. doi: 10.1111/ner.12624. Epub 2017 May 31. Review.


An Optimized IES Method and Its Inhibitory Effects and Mechanisms on Food Intake and Body Weight in Diet-Induced Obese Rats: IES for Obesity.

Wan X, Yin J, Foreman R, Chen JDZ.

Obes Surg. 2017 Dec;27(12):3215-3222. doi: 10.1007/s11695-017-2743-1.


Anti-inflammatory effects and mechanisms of vagal nerve stimulation combined with electroacupuncture in a rodent model of TNBS-induced colitis.

Jin H, Guo J, Liu J, Lyu B, Foreman RD, Yin J, Shi Z, Chen JDZ.

Am J Physiol Gastrointest Liver Physiol. 2017 Sep 1;313(3):G192-G202. doi: 10.1152/ajpgi.00254.2016. Epub 2017 May 25.


Urotensin-II peptidomimetic incorporating a non-reducible 1,5-triazole disulfide bond reveals a pseudo-irreversible covalent binding mechanism to the urotensin G-protein coupled receptor.

Pacifico S, Kerckhoffs A, Fallow AJ, Foreman RE, Guerrini R, McDonald J, Lambert DG, Jamieson AG.

Org Biomol Chem. 2017 May 31;15(21):4704-4710. doi: 10.1039/c7ob00959c.


Case 15-2017 - A 27-Year-Old Woman with Anemia, Thrombocytosis, and Skin Lesions after Travel Abroad.

Mansour MK, Letourneau AR, Wallace ZS, Fintelmann FJ, Foreman RK.

N Engl J Med. 2017 May 18;376(20):1973-1981. doi: 10.1056/NEJMcpc1616396. No abstract available.


Inhibitory Effects and Mechanisms of Electroacupuncture via Chronically Implanted Electrodes on Stress-Induced Gastric Hypersensitivity in Rats With Neonatal Treatment of Iodoacetamide.

Zhou J, Li S, Wang Y, Foreman RD, Yin J, Zhang S, Chen JDZ.

Neuromodulation. 2017 Dec;20(8):767-773. doi: 10.1111/ner.12602. Epub 2017 Apr 10.


Effects and mechanisms of auricular electroacupuncture on gastric hypersensitivity in a rodent model of functional dyspepsia.

Zhou J, Li S, Wang Y, Lei Y, Foreman RD, Yin J, Chen JD.

PLoS One. 2017 Mar 28;12(3):e0174568. doi: 10.1371/journal.pone.0174568. eCollection 2017.


A case of hypertrichosis lanuginosa acquisita as a sign of malignancy.

Frank JA, Rojek N, Foreman RS.

Eur J Dermatol. 2017 Feb 1;27(1):66-67. doi: 10.1684/ejd.2016.2901. No abstract available.


Translational neurocardiology: preclinical models and cardioneural integrative aspects.

Ardell JL, Andresen MC, Armour JA, Billman GE, Chen PS, Foreman RD, Herring N, O'Leary DS, Sabbah HN, Schultz HD, Sunagawa K, Zucker IH.

J Physiol. 2016 Jul 15;594(14):3877-909. doi: 10.1113/JP271869. Epub 2016 Jun 17. Review.


Recurrent lobular capillary hemangiomas in a patient with neurofibromatosis type 1 (NF1) and von Hippel-Lindau syndrome (VHL).

Haitz K, Mikailov A, Foreman R, Zimarowski MJ, Seo SJ.

JAAD Case Rep. 2015 Oct 17;1(6):368-70. doi: 10.1016/j.jdcr.2015.08.012. eCollection 2015 Nov. No abstract available.


Time to presentation and 12-month health outcomes in patients presenting to the emergency department with symptoms of possible acute coronary syndrome.

Cullen L, Greenslade JH, Menzies L, Leong A, Than M, Pemberton C, Aldous S, Pickering J, Dalton E, Crosling B, Foreman R, Parsonage WA.

Emerg Med J. 2016 Jun;33(6):390-5. doi: 10.1136/emermed-2015-204978. Epub 2016 Jan 18.


Electrical neuromodulation at acupoint ST36 normalizes impaired colonic motility induced by rectal distension in dogs.

Jin H, Liu J, Foreman RD, Chen JD, Yin J.

Am J Physiol Gastrointest Liver Physiol. 2015 Sep 1;309(5):G368-76. doi: 10.1152/ajpgi.00467.2014. Epub 2015 Jun 25.


Mechanisms of cardiac pain.

Foreman RD, Garrett KM, Blair RW.

Compr Physiol. 2015 Apr;5(2):929-60. doi: 10.1002/cphy.c140032. Review.


Hyperglycemia-induced small intestinal dysrhythmias attributed to sympathovagal imbalance in normal and diabetic rats.

Ouyang X, Li S, Foreman R, Farber J, Lin L, Yin J, Chen JD.

Neurogastroenterol Motil. 2015 Mar;27(3):406-15. doi: 10.1111/nmo.12506. Epub 2015 Jan 28.


Chronic Electrical Stimulation at Acupoints Reduces Body Weight and Improves Blood Glucose in Obese Rats via Autonomic Pathway.

Liu J, Jin H, Foreman RD, Lei Y, Xu X, Li S, Yin J, Chen JD.

Obes Surg. 2015 Jul;25(7):1209-16. doi: 10.1007/s11695-014-1521-6.


Neurostimulation for the treatment of axial back pain: a review of mechanisms, techniques, outcomes, and future advances.

Deer T, Pope J, Hayek S, Narouze S, Patil P, Foreman R, Sharan A, Levy R.

Neuromodulation. 2014 Oct;17 Suppl 2:52-68. doi: 10.1111/j.1525-1403.2012.00530.x. Review.


An in vitro cord formation assay identifies unique vascular phenotypes associated with angiogenic growth factors.

Falcon BL, Swearingen M, Gough WH, Lee L, Foreman R, Uhlik M, Hanson JC, Lee JA, McClure DB, Chintharlapalli S.

PLoS One. 2014 Sep 11;9(9):e106901. doi: 10.1371/journal.pone.0106901. eCollection 2014.


The appropriate use of neurostimulation: new and evolving neurostimulation therapies and applicable treatment for chronic pain and selected disease states. Neuromodulation Appropriateness Consensus Committee.

Deer TR, Krames E, Mekhail N, Pope J, Leong M, Stanton-Hicks M, Golovac S, Kapural L, Alo K, Anderson J, Foreman RD, Caraway D, Narouze S, Linderoth B, Buvanendran A, Feler C, Poree L, Lynch P, McJunkin T, Swing T, Staats P, Liem L, Williams K; Neuromodulation Appropriateness Consensus Committee.

Neuromodulation. 2014 Aug;17(6):599-615; discussion 615. doi: 10.1111/ner.12204.


The appropriate use of neurostimulation: avoidance and treatment of complications of neurostimulation therapies for the treatment of chronic pain. Neuromodulation Appropriateness Consensus Committee.

Deer TR, Mekhail N, Provenzano D, Pope J, Krames E, Thomson S, Raso L, Burton A, DeAndres J, Buchser E, Buvanendran A, Liem L, Kumar K, Rizvi S, Feler C, Abejon D, Anderson J, Eldabe S, Kim P, Leong M, Hayek S, McDowell G 2nd, Poree L, Brooks ES, McJunkin T, Lynch P, Kapural L, Foreman RD, Caraway D, Alo K, Narouze S, Levy RM, North R; Neuromodulation Appropriateness Consensus Committee.

Neuromodulation. 2014 Aug;17(6):571-97; discussion 597-8. doi: 10.1111/ner.12206.


The appropriate use of neurostimulation of the spinal cord and peripheral nervous system for the treatment of chronic pain and ischemic diseases: the Neuromodulation Appropriateness Consensus Committee.

Deer TR, Mekhail N, Provenzano D, Pope J, Krames E, Leong M, Levy RM, Abejon D, Buchser E, Burton A, Buvanendran A, Candido K, Caraway D, Cousins M, DeJongste M, Diwan S, Eldabe S, Gatzinsky K, Foreman RD, Hayek S, Kim P, Kinfe T, Kloth D, Kumar K, Rizvi S, Lad SP, Liem L, Linderoth B, Mackey S, McDowell G, McRoberts P, Poree L, Prager J, Raso L, Rauck R, Russo M, Simpson B, Slavin K, Staats P, Stanton-Hicks M, Verrills P, Wellington J, Williams K, North R; Neuromodulation Appropriateness Consensus Committee.

Neuromodulation. 2014 Aug;17(6):515-50; discussion 550. doi: 10.1111/ner.12208.


A novel CDK9 inhibitor shows potent antitumor efficacy in preclinical hematologic tumor models.

Yin T, Lallena MJ, Kreklau EL, Fales KR, Carballares S, Torrres R, Wishart GN, Ajamie RT, Cronier DM, Iversen PW, Meier TI, Foreman RT, Zeckner D, Sissons SE, Halstead BW, Lin AB, Donoho GP, Qian Y, Li S, Wu S, Aggarwal A, Ye XS, Starling JJ, Gaynor RB, de Dios A, Du J.

Mol Cancer Ther. 2014 Jun;13(6):1442-56. doi: 10.1158/1535-7163.MCT-13-0849. Epub 2014 Mar 31.


Comparison of burst and tonic spinal cord stimulation on spinal neural processing in an animal model.

Tang R, Martinez M, Goodman-Keiser M, Farber JP, Qin C, Foreman RD.

Neuromodulation. 2014 Feb;17(2):143-51. doi: 10.1111/ner.12117. Epub 2013 Sep 24.


Therapeutic potential of spinal cord stimulation for gastrointestinal motility disorders: a preliminary rodent study.

Song GQ, Sun Y, Foreman RD, Chen JD.

Neurogastroenterol Motil. 2014 Mar;26(3):377-84. doi: 10.1111/nmo.12273. Epub 2013 Dec 17.


Oral glycopyrrolate for refractory pediatric and adolescent hyperhidrosis.

Kumar MG, Foreman RS, Berk DR, Bayliss SJ.

Pediatr Dermatol. 2014 Jan-Feb;31(1):e28-30. doi: 10.1111/pde.12236. Epub 2013 Nov 25.


Testicular infarction after angioembolization of an ipsilateral renal angiomyolipoma.

Cummings CT, Foreman R, Killoran TP, Krane JF, O'Leary M.

Urology. 2013 Nov;82(5):995-7. doi: 10.1016/j.urology.2013.04.034. Epub 2013 Aug 23. No abstract available.


Skin blood flow response to locally applied mechanical and thermal stresses in the diabetic foot.

Jan YK, Shen S, Foreman RD, Ennis WJ.

Microvasc Res. 2013 Sep;89:40-6. doi: 10.1016/j.mvr.2013.05.004. Epub 2013 May 30.


The Brucella abortus general stress response system regulates chronic mammalian infection and is controlled by phosphorylation and proteolysis.

Kim HS, Caswell CC, Foreman R, Roop RM 2nd, Crosson S.

J Biol Chem. 2013 May 10;288(19):13906-16. doi: 10.1074/jbc.M113.459305. Epub 2013 Apr 1.


Post-disaster Gulf Coast recovery using telehealth.

Kim TJ, Arrieta MI, Eastburn SL, Icenogle ML, Slagle M, Nuriddin AH, Brantley KM, Foreman RD, Buckner AV.

Telemed J E Health. 2013 Mar;19(3):200-10. doi: 10.1089/tmj.2012.0100. Epub 2013 Feb 21.


Neural mechanisms of spinal cord stimulation.

Foreman RD, Linderoth B.

Int Rev Neurobiol. 2012;107:87-119. doi: 10.1016/B978-0-12-404706-8.00006-1. Review.


Differential effects of intravesical resiniferatoxin on excitability of bladder spinal neurons upon colon-bladder cross-sensitization.

Malykhina AP, Qin C, Lei Q, Pan XQ, Greenwood-Van Meerveld B, Foreman RD.

Brain Res. 2013 Jan 23;1491:213-24. doi: 10.1016/j.brainres.2012.11.003. Epub 2012 Nov 9.

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